Flow cytometric measurement of antiplatelet antibodies.

Abstract:

:A flow cytometric technic was developed to detect platelet surface-bound immunoglobulin in patients with thrombocytopenia. Elevated platelet surface IgG and/or IgM was detected in 90.9% of patients with immune thrombocytopenia purpura (ITP). False positive results occurred in 9.3% of patients with nonimmune thrombocytopenia usually associated with sepsis. False negatives occurred most frequently in adults with chronic ITP. Measurement of platelet surface immunoglobulin with this flow cytometric technic helps differentiate immune from nonimmune thrombocytopenia.

journal_name

Am J Clin Pathol

authors

Rosenfeld CS,Nichols G,Bodensteiner DC

doi

10.1093/ajcp/87.4.518

subject

Has Abstract

pub_date

1987-04-01 00:00:00

pages

518-22

issue

4

eissn

0002-9173

issn

1943-7722

journal_volume

87

pub_type

杂志文章
  • Epstein-Barr Virus-Positive Extranodal Marginal Zone Lymphoma of Bronchial-Associated Lymphoid Tissue in the Posttransplant Setting: An Immunodeficiency-Related (Posttransplant) Lymphoproliferative Disorder?

    abstract:Objectives:Posttransplant lymphoproliferative disorders (PTLDs) are a heterogeneous group of hematolymphoid proliferations arising in the context of chronic immunosuppression. The common and indolent B-cell lymphomas, including extranodal marginal zone lymphomas (ENMZLs) of mucosa-associated lymphoid tissue (MALT), are...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章,评审

    doi:10.1093/ajcp/aqx134

    authors: Cassidy DP,Vega F,Chapman JR

    更新日期:2017-12-20 00:00:00

  • Rat antikeratin monoclonal antibodies are specific for stratified squamous epithelia.

    abstract::Seven monoclonal antibodies of rat origin were generated against human epidermal keratins and were assayed by immunoblot and by immunoperoxidase staining of frozen sections from various human epithelial tissues. By immunoblotting, the antibodies recognized two different subsets of high molecular weight cytokeratin pol...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/89.3.315

    authors: Chin NW,Lai BT,Lanks KW

    更新日期:1988-03-01 00:00:00

  • Quality school: an innovative approach to laboratory quality practices training.

    abstract::The quality management program in the Division of Transfusion Medicine at our institution had evolved to the point that the program generally was perceived to be the sole responsibility of our Quality Unit (which was administratively independent of day-to-day operations). It became clear that this administrative model...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/UHKMFRFTDRJ7MJ58

    authors: Foss ML,Moore SB

    更新日期:2005-10-01 00:00:00

  • Effects of time, platelet concentration, and sex on the human platelet aggregation response.

    abstract::The platelet aggregation responses induced by adenosine diphosphate (ADP) and collagen were characterized by parameters defining rate and extent of reaction. Values were compared on the basis of platelet concentration, time elapsed between sample collection and test performance, and sex of donors. Rate and extent of a...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/71.3.263

    authors: Roper P,Drewinko B,Hasler D,Johnston D,Hester J,Freireich EJ

    更新日期:1979-03-01 00:00:00

  • Cytologic/histologic correlation for quality control in cervicovaginal cytology. Experience with 1,582 paired cases.

    abstract::For quality-control purposes, federal regulations require cytology laboratories to compare Papanicolaou smear and cervical biopsy reports, if available, and determine the cause of any discrepancies. The authors reviewed 56,497 cervicovaginal smears, of which 1,582 (2.8%) had a subsequent cervical biopsy or endocervica...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/103.1.32

    authors: Joste NE,Crum CP,Cibas ES

    更新日期:1995-01-01 00:00:00

  • High-density lipoprotein cholesterol. Significant bias between methods.

    abstract::Cholesterol content of the high-density lipoproteins has become of interest in evaluating the risk of development of coronary heart disease. There is an inverse relationship between high-density lipoprotein cholesterol and risk. The authors found a significant bias (11.1 mg/dl; 0.289 mmol/l) in a comparison of a rapid...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/71.5.564

    authors: Gerson B,Dean L,Copeland BE

    更新日期:1979-05-01 00:00:00

  • Pathology archive: evaluation of integrity, regulatory compliance, and construction of searchable database from print reports.

    abstract::Tissue repositories maintained by pathology departments represent an abundant resource of clinically annotated human specimens. The storage expenses associated with pathology archives are known to administrators of most pathology departments. However, such basic repository characteristics as the quality of stored mate...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/AJCP3CVA2NAVUUVU

    authors: Smith MA,Barnes EL,Chiosea SI

    更新日期:2011-05-01 00:00:00

  • Duplicate prealbumin bands in urine. Association with hepatorenal failure.

    abstract::By electrophoresis, prealbumin is seen as a discrete band anodic to the albumin fraction. Cases of duplicate bands in the prealbumin region have been described previously in serum, cerebrospinal fluid, and urine, and have had an association with varied clinical entities. The authors describe a novel association of sev...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/101.4.475

    authors: Castañeda L,Ruiz P

    更新日期:1994-04-01 00:00:00

  • Hepatitis B (surface) antigen testing by radioimmunoassaymexperience in a very large volunteer donor population.

    abstract::The results of hepatitis B surface antigen (HBs-Ag) testing in a large volunteer blood donor population are described. Counterelectrophoresis and three versions of solid-phase radioimmunoassay technic are compared and evaluated. Initial results suggested that the radioimmunoassay technic are compared and evaluated. In...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/63.6.847

    authors: Dodd RY,Ni LY,Mallin WS,Greenwalt TJ

    更新日期:1975-06-01 00:00:00

  • MUC4 expression increases progressively in pancreatic intraepithelial neoplasia.

    abstract::Pancreatic adenocarcinoma is believed to develop from histologically identifiable intraductal lesions known as pancreatic intraepithelial neoplasias (PanINs) that undergo a series of architectural, cytologic, and genetic changes, a progression model similar to the adenoma-carcinoma sequence in the colon. The apomucin ...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/7Y7N-M1WM-R0YK-M2VA

    authors: Swartz MJ,Batra SK,Varshney GC,Hollingsworth MA,Yeo CJ,Cameron JL,Wilentz RE,Hruban RH,Argani P

    更新日期:2002-05-01 00:00:00

  • Repeat thyroid nodule fine-needle aspiration in patients with initial benign cytologic results.

    abstract::Fine-needle aspiration (FNA) is the standard of care for the initial workup of thyroid nodules, but there is no consensus algorithm to manage patients with benign results. We examined performance characteristics of initial and repeat satisfactory FNAs for all 402 patients who underwent thyroid surgery during a recent ...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/4AXL-DMN1-JRPM-TX5P

    authors: Flanagan MB,Ohori NP,Carty SE,Hunt JL

    更新日期:2006-05-01 00:00:00

  • Liquid-based Papanicolaou tests in endometrial carcinoma diagnosis. Performance, error root cause analysis, and quality improvement.

    abstract::Recent reports show that the sensitivity of endometrial carcinoma detection on liquid-based Papanicolaou (Pap) tests (88%) is considerably higher than that reported on conventional Pap smears (20%-30%), although few laboratories have corroborated these results. We performed a 5-year retrospective review of all liquid-...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/AJCPLFBK1A2XJDQI

    authors: Sams SB,Currens HS,Raab SS

    更新日期:2012-02-01 00:00:00

  • Influence of blood collection systems on the prothrombin time and international sensitivity index determined with human and rabbit thromboplastin reagents.

    abstract::Three brands of blood collection tubes were studied for their influence on the prothrombin time (PT) and international sensitivity index (ISI) for 5 commercial thromboplastin reagents. With all reagents, PTs were shorter in Vacutainer (Becton Dickinson Vacutainer Systems, Plymouth, England) samples than in S-Monovette...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/NW194EAMD4WMEHJD

    authors: van den Besselaar AM,Hoekstra MM,Witteveen E,Didden JH,van der Meer FJ

    更新日期:2007-05-01 00:00:00

  • Incidence of diagnostic change in colorectal polyp specimens after deeper sectioning at 2 different laboratories staffed by the same pathologists.

    abstract:OBJECTIVES:To calculate the incidence of nondiagnostic (ND) colorectal (CR) polyp cases in which deeper tissue sectioning rendered new diagnostic information--particularly adenomas--in 2 laboratories staffed by the same pathologists. METHODS:After initial diagnosis, 100 ND CR polyps from each laboratory were reexamine...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/AJCPPXU66QZAZNYN

    authors: Nielsen JA,Lager DJ,Lewin M,Weber JJ,Roberts CA

    更新日期:2013-08-01 00:00:00

  • Soft agar culture of human transitional cell carcinoma colonies from urine.

    abstract::Soft-agar culture of transitional cell carcinoma colonies from urine, bladder irrigation fluid, and transurethral resection solid tumor specimens demonstrate generally better growth of tumor cell colonies from urine than from irrigation fluid. Growth of tumor colonies from urine was adequate to evaluate presence of tu...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/78.5.690

    authors: Kirkels WJ,Pelgrim OE,Debruyne FM,Vooijs GP,Herman CJ

    更新日期:1982-11-01 00:00:00

  • Early monitoring of serum cardiac troponin I for assessment of coronary reperfusion following thrombolytic therapy.

    abstract::The authors report the use of cardiac troponin I (cTnI) for the early, noninvasive determination of coronary reperfusion following thrombolytic therapy. Cardiac troponin I, creatine kinase (CK)-MB, and myoglobin concentrations were measured in early serum specimens at 30, 60, and 90 minutes after initiation of therapy...

    journal_title:American journal of clinical pathology

    pub_type: 临床试验,杂志文章

    doi:10.1093/ajcp/105.1.6

    authors: Apple FS,Henry TD,Berger CR,Landt YA

    更新日期:1996-01-01 00:00:00

  • Prospective double-blind clinical trial of bovine, human, and rabbit thromboplastins in monitoring long-term oral anticoagulation.

    abstract::A prospective double-blind trial was performed to investigate the safety of long-term oral anticoagulant control when dosaged adjustment depends on the prothrombin times assessed with one type of thromboplastin being calculated as if assayed by another type. The three main types of thromboplastin, i.e., bovine (Thromb...

    journal_title:American journal of clinical pathology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/ajcp/75.3.297

    authors: Boekhout-Mussert MJ,van der Kolk-Schaap PJ,Hermans J,Loeliger EA

    更新日期:1981-03-01 00:00:00

  • Touch Preps of Products of Conception for Rule-Out Ectopic Pregnancy:  A Viable Alternative to Frozen Section.

    abstract:OBJECTIVES:Tissue confirmation of the intrauterine location of a pregnancy can be difficult grossly, necessitating a frozen section diagnosis. First-trimester tissue is often scant and can be exhausted by frozen section. We examined 39 endometrial curettings performed for rule-out ectopic pregnancy by touch prep to exa...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/aqw048

    authors: Chen AL,Tambouret RH,Roberts DJ

    更新日期:2016-06-01 00:00:00

  • Tubal and tubo-endometrioid metaplasia of the uterine cervix. Unemphasized features that may cause problems in differential diagnosis: a report of 25 cases.

    abstract::Twenty-five cases of tubal or tubo-endometrioid metaplasia that occurred in patients from 21 to 51 years of age (mean 39 years) are described. The majority of the cases were seen in consultation. They were referred because of diagnostic problems resulting from features that have received little emphasis. The metaplasi...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/103.5.618

    authors: Oliva E,Clement PB,Young RH

    更新日期:1995-05-01 00:00:00

  • Identification of monoclonal immunoglobulins and quantitative immunoglobulin abnormalities in hairy cell leukemia and chronic lymphocytic leukemia.

    abstract::Serum and urine samples from 161 cases of hairy cell leukemia (HCL) and 50 cases of chronic lymphocytic leukemia (CLL) were analyzed for monoclonal immunoglobulin (MIg) by using a combination of high-resolution protein electrophoresis, immunoelectrophoresis, and immunofixation. Quantitative immunoglobulin analysis als...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/102.5.580

    authors: Hansen DA,Robbins BA,Bylund DJ,Piro LD,Saven A,Ellison DJ

    更新日期:1994-11-01 00:00:00

  • Strict vs lenient criteria for elution testing: comparison of yields between two tertiary care medical centers.

    abstract::In this study, 2 patient populations, using different elution strategies, were compared to evaluate eluate yields under more and less restrictive conditions. An informative eluate was defined as one in which an antibody that could be clinically significant was detected in the eluate but was not detectable in the plasm...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/AJCPRVDCKI5CE2CH

    authors: Veeraputhiran MK,Pesek GA,Blackall DP

    更新日期:2011-09-01 00:00:00

  • Hepatic ALECT-2 amyloidosis causing portal hypertension and recurrent variceal bleeding: a case report and review of the literature.

    abstract:OBJECTIVES:To examine laser microdissection and mass spectrometry (LMD-MS), which has emerged as a new tool to aid in typing amyloid proteins. RESULTS:ALECT-2 is a potential cause of hepatic amyloidosis best detected by LMD-MS. METHODS:One of the more recently reported proteins is ALECT-2 (leukocyte cell-derived chem...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章,评审

    doi:10.1309/AJCPCLK54RKXTRDI

    authors: Damlaj M,Amre R,Wong P,How J

    更新日期:2014-02-01 00:00:00

  • The immunochemical characterization of the light chains in the mesangial IgA deposits in IgA nephropathy.

    abstract::The immunochemical characterization of the light chains of the mesangial immunoglobulin A (IgA) deposits were studied in 45 patients with IgA nephropathy. Kappa and lambda light chains were detected with direct immunofluorescence (IF) method, using monospecific rabbit anti-human anti-kappa and anti-lambda anti-sera. T...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/85.5.548

    authors: Lai KN,Chan KW,Mac-Moune F,Ho CP,Yan KW,Lam CW,Vallance-Owen J

    更新日期:1986-05-01 00:00:00

  • Vitamin E does not modify HDL-cholesterol.

    abstract::Vitamin E has been reported to increase serum high-density lipoprotein (HDL) cholesterol. Given the known inverse relationship between HDL-cholesterol and risk of developing coronary artery disease, these preliminary results require verification or refutation. In the present study, 39 volunteers were given 600 U of vi...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/77.1.86

    authors: Howard DR,Rundell CA,Batsakis JG

    更新日期:1982-01-01 00:00:00

  • American Burkitt's lymphoma-hand-mirror variant. A detailed investigation of cytologic, ultrastructural, and immunologic features.

    abstract::Previous studies of patients with lymphoid malignancies have suggested a relationship between survival and the presence of more than 40% hard-mirror cells in the bone marrow. This report represents the first detailed study of a patient with American Burkitt's lymphoma with numerous hand-mirror cells in the bone marrow...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/70.6.937

    authors: Schumacher HR,Rainey T,Davidson L,Simon D,Strong M,Creegan WJ,Holloway ML,Stass SA

    更新日期:1978-12-01 00:00:00

  • Spindle and histiocytoid (epithelioid) hemangioendothelioma. Primary in lymph node.

    abstract::A 52-year-old woman presented with a solid spindle cell primary tumor of the lymph node. On light microscopic examination, mitoses and cellular atypia were absent. Electron-microscopic studies showed endothelial cell differentiation. Intracytoplasmic localization of Factor VIII-related antigen was demonstrated by the ...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/85.6.731

    authors: Silva EG,Phillips MJ,Langer B,Ordonez NG

    更新日期:1986-06-01 00:00:00

  • Phenotype of the hairy cells of leukemic reticuloendotheliosis defined by monoclonal antibodies.

    abstract::Hairy cell populations of greater than 90 purity were prepared from six samples obtained from four patients with leukemic reticuloendotheliosis (LRE). These then were analyzed for surface immunoglobulin (SIg) and antigens specified by a panel of monoclonal antibodies. The hairy cells from all patients displayed SIg an...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/79.4.431

    authors: Janckila AJ,Stelzer GT,Wallace JH,Yam LT

    更新日期:1983-04-01 00:00:00

  • Prognostic factors in primary mucinous breast carcinoma.

    abstract::Two hundred seven mucinous breast carcinomas were morphologically classified into two different groups: pure mucinous carcinomas consisting only of areas with small epithelial islands of solid tumor floating in abundant extracellular mucin, and mixed carcinomas where the tumor contains large areas of mucin, as well as...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/87.2.155

    authors: Rasmussen BB,Rose C,Christensen IB

    更新日期:1987-02-01 00:00:00

  • Susceptibility testing with anaerobic blood culture isolates. Comparison of a rapid, direct methods with standardized method.

    abstract::The results of a direct anaerobic susceptibility testing method were compared with those of a standardized method. Seventy-three blood culture isolates and eight antimicrobial agents were used. The results of the direct and standardized testing methods were within one two-fold dilution for 95.2% of the 584 anaerobe-an...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/73.4.558

    authors: Murray PR,Christman JL

    更新日期:1980-04-01 00:00:00

  • The usefulness of immunohistochemistry in the diagnosis of follicular lymphoma in bone marrow biopsy specimens.

    abstract::We used a panel of paraffin antibodies to determine whether neoplastic and nonneoplastic lymphoid aggregates in the bone marrow can be distinguished reliably. Formalin-fixed, paraffin-embedded bone marrow core biopsy specimens with lymphoid aggregates were stained using primary antibodies directed against bcl-2, bcl-6...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/W3QX-WJ1C-WG2K-225V

    authors: West RB,Warnke RA,Natkunam Y

    更新日期:2002-04-01 00:00:00