Proteomic evaluation of archival cytologic material using SELDI affinity mass spectrometry: potential for diagnostic applications.

abstract：:Fine-needle aspiration (FNA) is the standard of care for the initial workup of thyroid nodules, but there is no consensus algorithm to manage patients with benign results. We examined performance characteristics of initial and repeat satisfactory FNAs for all 402 patients who underwent thyroid surgery during a recent ...

journal_title：American journal of clinical pathology

authors： Flanagan MB,Ohori NP,Carty SE,Hunt JL

更新日期：2006-05-01 00:00:00

abstract：:The ability of the cervical Papanicolaou (Pap) smear to detect cervicitis associated with Chlamydia trachomatis was investigated. Cultures and cervical cytology samples were obtained from 487 women seen at the Mayo Clinic Department of Obstetrics and Gynecology and at the Sexually Transmitted Disease clinic of the Olm...

journal_title：American journal of clinical pathology

authors： Dorman SA,Danos LM,Wilson DJ,Noller KL,Malkasian GD,Goellner JR,Smith TF

更新日期：1983-04-01 00:00:00

abstract：:The reactivity of eight preferential B-cell (L26, 4KB5, and KiB3) and T-cell (polyclonal CD3, Leu22, MT-1, UCHL-1, and OPD4) antibodies which detect paraffin-resistant antigens was examined by a three-step immunoperoxidase technique in 111 formalin-fixed, paraffin-embedded diffuse aggressive non-Hodgkin's lymphomas (N...

journal_title：American journal of clinical pathology

authors： Chadburn A,Knowles DM

更新日期：1994-09-01 00:00:00

abstract：:The May-Hegglin anomaly is one of the rare forms of heriditary thrombocytopenia. Since fewer than 100 cases of May-Hegglin anomaly have been described to date, major controversies regarding the adequacy of hemostasis in vivo and abnormalities of platelet function in vitro continue to prevail. This report describes the...

journal_title：American journal of clinical pathology

authors： Hamilton RW,Shaikh BS,Ottie JN,Storch AE,Saleem A,White JG

更新日期：1980-11-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection may be complicated by non-Hodgkin's lymphoma. We describe eight cases of B-cell extranodal non-Hodgkin's lymphoma occurring during the course of chronic HCV-related hepatic disease (low-grade of mucosa-associated lymphoid tissue [MALT]-type; diffuse large cell; Burkitt; diffuse small ...

journal_title：American journal of clinical pathology

authors： Ascoli V,Lo Coco F,Artini M,Levrero M,Martelli M,Negro F

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVES:The National Cancer Institute (NCI) National Clinical Trials Network performs phase II and III clinical trials, which increasingly rely on the submission of diagnostic formalin-fixed, paraffin-embedded tissue blocks for biomarker assessment. Simultaneously, advances in precision oncology require that clinica...

journal_title：American journal of clinical pathology

authors： Makhlouf H,Watson MA,Lankes HA,Weil C,Dickler M,Birrer M,Moskaluk C,Ramirez NC,Okby N,Alonsozana E,Barnes M,Goldman EB,Enos R,Lubensky I

更新日期：2020-01-02 00:00:00

abstract：:A 26-year-old woman who had undergone orthotopic heart transplantation because of dilative cardiomyopathy received a triple-drug immunosuppressive regimen (cyclosporine A, azathioprine, and prednisolone). During her relatively frequent episodes of acute rejection, she was treated with methylprednisolone and repeated a...

journal_title：American journal of clinical pathology

authors： Kemnitz J,Cremer J,Gebel M,Uysal A,Haverich A,Georgii A

更新日期：1990-07-01 00:00:00

abstract：:A 30-year-old previously healthy man developed cervical adenopathy associated with mild constitutional symptoms. Corynebacterium ovis was isolated in pure culture from lymph node tissue on two separate occasions, and small gram positive organisms were identified in both lymph nodes with tissue gram stain. Histopatholo...

journal_title：American journal of clinical pathology

authors： Goldberger AC,Lipsky BA,Plorde JJ

更新日期：1981-10-01 00:00:00

abstract：:The authors analyzed the frequency of immunophenotypic abnormalities in 1,474 cases of routinely fixed, paraffin-embedded B-lineage non-Hodgkin's lymphomas. B-lineage was determined by immunoreactivity for CD20 (L26, 92%); CD45RA (4KB5, an additional 3%) or immunoglobulin (Ig) light chain restriction (remaining 5%). C...

journal_title：American journal of clinical pathology

authors： Gelb AB,Rouse RV,Dorfman RF,Warnke RA

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVES:The 2014 Bethesda System (TBS 2014) guidelines for reporting cervical cytology revised the age for reporting benign endometrial cells (BECs) from 40 years or older to age 45 years or older. We evaluated this change and further investigated if extending the reporting age to 50 years or older may be acceptable...

journal_title：American journal of clinical pathology

authors： Hernandez A,Schatz-Siemers N,Zhou F,Brandler TC,Negron R,Modi L,Elgert PA,Simsir A

更新日期：2020-08-05 00:00:00

abstract：:Human serum contains 2 isoforms of type-5 tartrate-resistant acid phosphatase (TRACP): 5a and 5b. TRACP-5b is osteoclastic. Our goal was to determine if serum TRACP-5a could originate from inflammatory macrophages (MPhi). We stained 246 paraffin-embedded tissue samples for TRACP using monoclonal antibody 9C5 (mab9C5) ...

journal_title：American journal of clinical pathology

authors： Janckila AJ,Slone SP,Lear SC,Martin A,Yam LT

更新日期：2007-04-01 00:00:00

abstract：:We aimed to establish whether morphologic parameters were prognostically important in a large series of breast phyllodes tumors in Asian women. Of 335 phyllodes tumors diagnosed at the Department of Pathology, Singapore General Hospital, Singapore, between January 1992 and December 2002, 250 (74.6%) were benign, 54 (1...

journal_title：American journal of clinical pathology

authors： Tan PH,Jayabaskar T,Chuah KL,Lee HY,Tan Y,Hilmy M,Hung H,Selvarajan S,Bay BH

更新日期：2005-04-01 00:00:00

abstract：:The pattern of spurious red blood cell parameters caused by serum cold agglutinins has been well characterized for the Coulter counters but not the Ortho ELT-8. The pattern consists of a spurious increase in mean corpuscular volume (MCV), a discrepancy between the hemoglobin and the hematocrit, the latter falsely redu...

journal_title：American journal of clinical pathology

authors： Solanki DL,Blackburn BC

更新日期：1985-02-01 00:00:00

abstract：:The international sensitivity index (ISI) calibration of point-of-care-test (POCT) prothrombin time (PT) whole blood monitors is complex, requiring manual PT testing of 60 patients' and 20 healthy subjects' plasma samples. The possibility of reducing these numbers was studied by a Monte Carlo Bootstrap study for 2 POC...

journal_title：American journal of clinical pathology

authors： Poller L,Keown M,Chauhan N,van den Besselaar AM,Tripodi A,Jespersen J,Shiach C

更新日期：2002-06-01 00:00:00

abstract：:A 3-year-old girl of Navajo heritage had intractable diarrhea beginning at 4 days of age and resulting in long-term hyperalimentation. Investigation before multivisceral transplantation included biopsies of the rectum, stomach, duodenum, and liver. The diagnosis of microvillus inclusion disease was established by docu...

journal_title：American journal of clinical pathology

authors： Schofield DE,Agostini RM Jr,Yunis EJ

更新日期：1992-07-01 00:00:00

abstract：:The Department of Laboratory Medicine, University of Washington, has explored various management of organizational approaches over the past seven years. The Centralized Processing Area supported by a computerized information system has evolved from these efforts. Despite a decrease in U.W. hospital usage since 1968-69...

journal_title：American journal of clinical pathology

authors： Nussbaum B,Minckler T,Roby R,Ackerman E

更新日期：1977-02-01 00:00:00

abstract：:Three cases of pulmonary squamous cell carcinoma (SCC) are described displaying a prominent microcystic pattern closely resembling microcystic adnexal carcinoma of the skin (MAC). The patients were 2 women and 1 man aged 72 to 83 years. Histologically, in addition to conventional SCC, all tumors showed striking microc...

journal_title：American journal of clinical pathology

authors： Weissferdt A,Moran CA

更新日期：2011-09-01 00:00:00

abstract：:Protease inhibitor serpin-B2 (plasminogen activator inhibitor-2 [PAI-2]) protects pRb from degradation in human papillomavirus (HPV)-18+ HeLa cells. Our objective was to assess whether the pRb-mediated HPV-suppressive effect of PAI-2 in cancer cell lines has implications in the outcome of HPV infections. Cervical biop...

journal_title：American journal of clinical pathology

authors： Syrjänen S,Naud P,Sarian L,Derchain S,Roteli-Martins C,Longatto-Filho A,Tatti S,Branca M,Erzen M,Hammes LS,Costa S,Syrjänen K

更新日期：2009-12-01 00:00:00

abstract：:The Auto Microbic System (AMS) is an almost completely automated system, capable of identifying Enterobacteriaceae after 8 hours, and some glucose nonfermenters after 13 hours of incubation. The Autobac ID system is a mechanized, computer-assisted system capable of identifying Enterobacteriaceae and many nonfermentati...

journal_title：American journal of clinical pathology

authors： Barry AL,Gavan TL,Badal RE,Telenson MJ

更新日期：1982-10-01 00:00:00

abstract：:In a computerized case registry, containing 220 cases of sinus histiocytosis with massive lymphadenopathy (SHML), 23 patients were identified with clinical or routine laboratory findings suggestive or diagnostic of immune dysfunction. We divided the abnormalities into hematologic autoantibodies (nine patients), glomer...

journal_title：American journal of clinical pathology

authors： Foucar E,Rosai J,Dorfman RF,Eyman JM

更新日期：1984-11-01 00:00:00

abstract：:Endometrial vascular changes similar to atherosclerosis of toxemia of pregnancy were described and graded in 217 consecutive endometrial biopsies of known early intrauterine pregnancy. Severe vascular changes were found in 23.5% of cases. Control material consisting of endometrial biopsies of patients with known cases...

journal_title：American journal of clinical pathology

authors： Lichtig C,Korat A,Deutch M,Brandes JM

更新日期：1988-09-01 00:00:00

abstract：:Chronic myeloproliferative diseases (MPDs) are not associated with consistent cytogenetic or molecular abnormalities. Demonstration of clonal cell growth by analysis of X-chromosome inactivation (XCI) patterns in females provides a promising tool for diagnosis. However, this technique can be complicated by excessive l...

journal_title：American journal of clinical pathology

authors： Mitterbauer G,Winkler K,Gisslinger H,Geissler K,Lechner K,Mannhalter C

更新日期：1999-07-01 00:00:00

abstract：:Platelet factor 4 (PF4)/heparin antibody, typically associated with heparin therapy, is reported in some heparin-naive people. Seroprevalence in the general population, however, remains unclear. We prospectively evaluated PF4/heparin antibody in approximately 4,000 blood bank donors using a commercial enzyme-linked im...

journal_title：American journal of clinical pathology

authors： Hursting MJ,Pai PJ,McCracken JE,Hwang F,Suvarna S,Lokhnygina Y,Bandarenko N,Arepally GM

更新日期：2010-11-01 00:00:00

abstract：:In patients infected with HIV, high-grade B-cell non-Hodgkin's lymphomas (NHL), including the small noncleaved cell (SNCC) category, exhibit pleomorphic features, which makes precise definition difficult. Sixty-nine pathologic specimens with HIV-related systemic lymphomas, including 42 SNCC, 20 immunoblastic lymphomas...

journal_title：American journal of clinical pathology

authors： Carbone A,Gloghini A,Gaidano G,Cilia AM,Bassi P,Polito P,Vaccher E,Saglio G,Tirelli U

更新日期：1995-05-01 00:00:00

abstract：:Specific esterase activity, a property generally ascribed to cells of granulocytic origin, was found in abnormal erythroid precursors obtained from the bone marrows of six patients with untreated erythroleukemia. These erythroblasts also showed nonspecific esterase activity. Neither specific nor nonspecific esterase a...

journal_title：American journal of clinical pathology

authors： Kass L

更新日期：1977-04-01 00:00:00

abstract：:Tumors and pseudotumors of the liver account for fewer than 2% of the tumors in children and vary considerably in incidence throughout the pediatric age range, with hepatoblastoma, infantile hemangioendothelioma, and mesenchymal hamartoma seen most frequently in the first 2 years of life and hepatocellular carcinoma, ...

journal_title：American journal of clinical pathology

authors： Stocker JT

更新日期：1998-04-01 00:00:00

abstract：:Anaplastic large cell lymphoma (ALCL) is recognized as 2 distinct diseases: anaplastic lymphoma kinase (ALK)+ ALCL and ALK- ALCL. ALK+ ALCL occurs in younger patients and has a better prognosis. Human T-cell lymphotropic virus (HTLV-1) is linked to the development of adult T-cell leukemia/lymphoma (ATLL), which freque...

journal_title：American journal of clinical pathology

authors： Gualco G,Chioato L,Weiss LM,Harrington WJ Jr,Bacchi CE

更新日期：2009-07-01 00:00:00

abstract：:The role of viruses in several renal diseases is not documented clearly. The authors attempted to localize envelope glycoproteins of Hantaan virus in biopsy specimens from patients with Korean hemorrhagic fever (KHF) as evidence of direct viral invasion of renal tissues. The authors studied sequential sections of kidn...

journal_title：American journal of clinical pathology

authors： Kim S,Kang ET,Kim YG,Han JS,Lee JS,Kim YI,Hall WC,Dalrymple JM,Peters CJ

更新日期：1993-10-01 00:00:00

abstract：:This article describes the occurrence of a coenurus, the encysted larval stage of a cestode of the genus Multiceps, within the axilla of a 40-year-old Nigerian woman. The patient had a history of intraductal carcinoma of the breast two years prior to the finding of an ipsilateral axillary mass. Pathologic evaluation o...

journal_title：American journal of clinical pathology

authors： Kurtycz DF,Alt B,Mack E

更新日期：1983-11-01 00:00:00

abstract：:By application of combined structural and functional analyses, most lymphoid neoplasms may be categorized as of T- or B-cell origin. T lymphocyte neoplasms include types of acute and chronic lymphocytic leukemias, certain cutaneous and node-based lymphomas, and lymphomas of thymocytes (convoluted lymphocytic lymphomas...

journal_title：American journal of clinical pathology

authors： Collins RD,Waldron JA,Glick AD

更新日期：1979-10-01 00:00:00