Abstract:
:Three cases of pulmonary squamous cell carcinoma (SCC) are described displaying a prominent microcystic pattern closely resembling microcystic adnexal carcinoma of the skin (MAC). The patients were 2 women and 1 man aged 72 to 83 years. Histologically, in addition to conventional SCC, all tumors showed striking microcystic changes characterized by nests and strands of basaloid squamous cells with central cystic spaces, peripheral palisading, and cytoplasmic clearing of the central tumor portions. Follow-up available for 2 patients revealed that 1 was alive at 76 months and 1 had died 38 months after diagnosis. Microcystic SCC is an unusual variant of SCC of the lung histologically mimicking tumors with glandular or adnexal differentiation and a particularly striking resemblance to MAC of the skin. The importance of the recognition of this growth pattern lies in the separation from other often less aggressive pulmonary neoplasms or metastatic disease from a cutaneous tumor.
journal_name
Am J Clin Patholjournal_title
American journal of clinical pathologyauthors
Weissferdt A,Moran CAdoi
10.1309/AJCP61QPWAZSPJAOsubject
Has Abstractpub_date
2011-09-01 00:00:00pages
436-41issue
3eissn
0002-9173issn
1943-7722pii
136/3/436journal_volume
136pub_type
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journal_title:American journal of clinical pathology
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更新日期:2019-09-09 00:00:00
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更新日期:2002-06-01 00:00:00
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journal_title:American journal of clinical pathology
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更新日期:1981-06-01 00:00:00
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更新日期:2005-01-01 00:00:00
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更新日期:1979-12-01 00:00:00
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更新日期:2009-08-01 00:00:00
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journal_title:American journal of clinical pathology
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更新日期:2013-11-01 00:00:00
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更新日期:2002-08-01 00:00:00
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journal_title:American journal of clinical pathology
pub_type: 杂志文章
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更新日期:1980-02-01 00:00:00
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更新日期:1991-05-01 00:00:00
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更新日期:2001-01-01 00:00:00
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更新日期:2011-03-01 00:00:00