Leu-M1 antigen expression in advanced (tumor) stage mycosis fungoides.

abstract：:With the new screening and treatment guidelines and the prospect of human papillomavirus vaccination for adolescents, the current total volume of Papanicolaou (Pap) tests will be significantly reduced. We used available data to assess the current supply and demand in the cytotechnology labor market and how an expected...

journal_title：American journal of clinical pathology

authors： Eltoum IA,Roberson J

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVES:To review various anticoagulation therapies and related laboratory monitoring issues, with a focus on factor X-related chromogenic assays. METHODS:A case-based approach is used to review pertinent published literatures and product inserts of anticoagulation drugs and to look back on clinical use of factor X...

journal_title：American journal of clinical pathology

authors： Wool GD,Lu CM,Education Committee of the Academy of Clinical Laboratory Physicians and Scientists.

更新日期：2013-11-01 00:00:00

abstract：:In the differential diagnosis of Spitz nevus vs malignant melanoma, patient age provides a critical piece of clinical information, because Spitz nevi occur mostly in children and melanomas occur mostly in adults. Nevertheless, there is overlap in the age distributions of Spitz nevus and melanoma. The issue to consider...

journal_title：American journal of clinical pathology

authors： Vollmer RT

更新日期：2004-06-01 00:00:00

abstract：:Serum bicarbonate testing has been reported to be inaccurate in several clinical studies. This prompted a search for systemic errors in bicarbonate testing devices, which has been inconclusive. The effect on serum bicarbonate level measurement of partially filling plain red-top (clot) vacutainer tubes was studied in h...

journal_title：American journal of clinical pathology

authors： Herr RD,Swanson T

更新日期：1992-02-01 00:00:00

abstract：:Two radioimmunoassay procedures (RIA-1 and RIA-2) were evaluated for the quantitation of prostatic acid phosphatase in serum and compared with the enzymatic method and counter immunoelectrophoresis method for their specificity and sensitivity. Sera from 168 patients were analyzed and these included: normals, 27; untre...

journal_title：American journal of clinical pathology

authors： Gupta MK,Rajaraman S,Gupta SK,Hewitt CB,Deodhar SD

更新日期：1981-10-01 00:00:00

abstract：:We evaluated a more efficient method of processing liquid-based cervical cytology specimens for human papillomavirus (HPV) DNA testing by Hybrid Capture II (HCII). Aliquots were made from 701 specimens in the following sequence: 4.0, 2.0, 1.0, 0.5, and 1.5 mL. The 4.0-mL aliquot was processed by the standard method (S...

journal_title：American journal of clinical pathology

authors： Castle PE,Garcia-Meijide M,Holladay EB,Chuke R,Payne J,Long A,Siefers H,Demuth F,Lorincz AT

更新日期：2005-02-01 00:00:00

abstract：:The reliability of "standard" plasmas used by clinical laboratories to assay factor VIII concentrations of patients' plasmas was studied by assessing the credibility of their reference values. Two of three commercial reference plasmas were considered to be unreliable. The third commercial reference plasma appeared to ...

journal_title：American journal of clinical pathology

authors： Harper TA,Bailey EL,Chauhan K

更新日期：1981-02-01 00:00:00

abstract：:Heterogeneous expression or amplification is a challenge to HER2 diagnostics. A guideline defines heterogeneity as the presence of between 5% and 50% cells with HER2/CEP17 ratios of more than 2.20. We audited the frequency of such cells and their clinical impact in the results from 2 pathology laboratories combined wi...

journal_title：American journal of clinical pathology

authors： Bartlett AI,Starcyznski J,Robson T,Maclellan A,Campbell FM,van de Velde CJ,Hasenburg A,Markopoulos C,Seynaeve C,Rea D,Bartlett JM

更新日期：2011-08-01 00:00:00

abstract：:In a case of secondary syphilis with gastric involvement, the clinical history and roentgenographic and gastroscopic examiniations initially suggested an infiltrative malignant neoplasm. However, macroscopic and histologic examination of the partial gastrectomy specimen demonstrated an erosive, inflammatory lesion. Su...

journal_title：American journal of clinical pathology

authors： Butz WC,Watts JC,Rosales-Wuintana S,Hicklin MD

更新日期：1975-06-01 00:00:00

abstract：:Under carefully controlled conditions in a clinical research ward, conjugated primary bile-acid concentrations were measured by a 125I-radioimmunoassay every eight hours for four days in seven healthy control subjects and ten patients with hepatic disease (five with cirrhosis, three with primary biliary cirrhosis and ...

journal_title：American journal of clinical pathology

authors： Engelking LR,Dasher CA,Hirschowitz BI

更新日期：1980-02-01 00:00:00

abstract：:Two monoclonal antibodies, UCD/AB 6.11 and UCD/PR 10.11, were evaluated for their patterns of immunohistochemical reactivity in a survey of paraffin-embedded human tissues by the avidin-biotin-immunoperoxidase technique. By two-dimensional immunoblotting, UCD/AB 6.11 reacts with keratin number 18 and UCD/PR 10.11 iden...

journal_title：American journal of clinical pathology

authors： Chan R,Edwards BF,Hu R,Rossitto PV,Min BH,Lund JK,Cardiff RD

更新日期：1988-04-01 00:00:00

abstract：OBJECTIVES:Human epidermal growth factor receptor 2 (HER2, ERBB2) testing is an important prognostic/predictive marker in breast cancer management, especially in selecting HER2-targeted treatment. American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP) guidelines address HER2 status and were...

journal_title：American journal of clinical pathology

authors： Long TH,Lawce H,Durum C,Moore SR,Olson SB,Gatter K,Troxell ML

更新日期：2015-08-01 00:00:00

abstract：:Anatomic pathology service is judged by accuracy of diagnosis and rapidity of reporting of that diagnosis to clinicians. Turnaround times have been used in anatomic pathology to show how long it take to produce a tissue report. Rapid tissue diagnosis is important to patients, clinicians, administrators, and anatomic p...

journal_title：American journal of clinical pathology

authors： Smith MT,Garvin AJ

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVES:Mesothelin (MSLN) is a differentiation antigen found to be overexpressed in intraductal papillary mucinous neoplasms (IPMNs) and is a potential treatment target in pancreatic ductal adenocarcinoma. METHODS:From institutional archives, 114 cases of resected pancreatic mucinous cysts were identified, includin...

journal_title：American journal of clinical pathology

authors： Frank R,Li S,Ahmad NA,Sepulveda AR,Jhala NC

更新日期：2014-09-01 00:00:00

abstract：:A patient with an acute burn was noticed to have spuriously elevated platelet counts on an automated system. The major factor accounting for this discrepancy was the presence of numerous microspherocytes which were in the same size range of platelets. It is thus important to add microspherocytosis as an additional cau...

journal_title：American journal of clinical pathology

authors： Akwari AM,Ross DW,Stass SA

更新日期：1982-02-01 00:00:00

abstract：:We studied the antigen expression profiles of 19 anaplastic large cell lymphoma (ALCL) cases by multiparameter flow cytometry. The neoplastic cells expressed CD45, HLA-DR, and CD30 in all cases. At least 1 T cell-associated antigen was expressed in each case (CD2, 12/17 [71%]; CD4, 12/19 [63%]; CD3, 6/19 [32%]; CD7, 6...

journal_title：American journal of clinical pathology

authors： Juco J,Holden JT,Mann KP,Kelley LG,Li S

更新日期：2003-02-01 00:00:00

abstract：:Seventy-nine mycelial-form stock cultures of Blastomyces dermatitidis, Coccidioides immitis, Histoplasma capsulatum, and morphologically similar fungi were extracted and tested by using commercial macroimmunodiffusion exoantigen test kits and the Centers for Disease Control (CDC) reference system for identifying funga...

journal_title：American journal of clinical pathology

authors： Denys GA,Newman MA,Standard PG

更新日期：1983-03-01 00:00:00

abstract：:In diagnostic pathology, decision-making skills are used to match the facts of a particular case to a diagnostic category. Ideally the diagnosis is established with "beyond a reasonable doubt" certainty, but substantial uncertainty orfrank diagnostic error can afflict the diagnostic process for a variety of reasons. M...

journal_title：American journal of clinical pathology

authors： Foucar E

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVES:Bone marrow (BM) biopsy specimens involved by systemic mastocytosis (SM) typically show multifocal, compact, dense aggregates of spindled mast cells (MCs). However, some cases lack aggregate formation and fulfill the World Health Organization 2008 criteria for SM, based on minor criteria. METHODS:We identif...

journal_title：American journal of clinical pathology

authors： Reichard KK,Chen D,Pardanani A,McClure RF,Howard MT,Kurtin PJ,Wood AJ,Ketterling RP,King RL,He R,Morice WG,Hanson CA

更新日期：2015-09-01 00:00:00

abstract：:Clq precipitins were assayed in a model system by absorption nephelometry. Polyethylene glycol was used to extract immune complexes so that sufficient sensitivity with minimal interference could be achieved. Using a double beam spectrophotometer, we found that the reaction of immune complexes with Clq occurred rapidly...

journal_title：American journal of clinical pathology

authors： Levinson SS,Goldman J

更新日期：1983-04-01 00:00:00

abstract：:Proper collection, handling, and storage of the blood alcohol specimen are essential in medicolegal cases involving the question of sobriety. A standard operating procedure is necessary to ensure maximum reliability. Comments are offered on the advantages of using blood specimens in preference to urine or tissue speci...

journal_title：American journal of clinical pathology

authors： Kaye S

更新日期：1980-11-01 00:00:00

abstract：:Peripheral blood samples of 23 patients who had hairy cell leukemia were examined for leukocyte alkaline phosphatase scores. Leukocyte alkaline phosphatase levels were elevated in seventeen patients (74%), were normal in six (26%), and were not decreased in any patient. The mean leukocyte alkaline phosphatase score wa...

journal_title：American journal of clinical pathology

authors： Aiba M,Raffa PP,Katayama I

更新日期：1980-09-01 00:00:00

abstract：OBJECTIVES:Sclerosing pneumocytomas are rare pulmonary neoplasms that are typically benign. However, rare patients experience progressive disease, and therapy targeting specific genetic underpinnings could be an attractive therapeutic option. Recent studies have found recurrent AKT 1 mutations in sclerosing pneumocytom...

journal_title：American journal of clinical pathology

authors： Boland JM,Lee HE,Barr Fritcher EG,Voss JS,Jessen E,Davila JI,Kipp BR,Graham RP,Maleszewski JJ,Yi ES

更新日期：2020-11-04 00:00:00

abstract：:Anaplastic thyroid carcinomas usually pose no problems in histologic diagnosis because of the obvious invasive growth, high cellularity, and frank anaplasia. Two cases of a variant of anaplastic thyroid carcinoma with peculiar gross and histologic features closely mimicking those of Riedel's thyroiditis are described ...

journal_title：American journal of clinical pathology

authors： Wan SK,Chan JK,Tang SK

更新日期：1996-04-01 00:00:00

abstract：:Tumors and pseudotumors of the liver account for fewer than 2% of the tumors in children and vary considerably in incidence throughout the pediatric age range, with hepatoblastoma, infantile hemangioendothelioma, and mesenchymal hamartoma seen most frequently in the first 2 years of life and hepatocellular carcinoma, ...

journal_title：American journal of clinical pathology

authors： Stocker JT

更新日期：1998-04-01 00:00:00

abstract：:Estrogen receptor (ER), progesterone receptor (PR), and c-ERBB2 (HER2/neu) are therapeutically and prognostically important markers in the management of breast carcinoma. They are not always analyzed in distant metastatic and locally recurrent breast cancers. We compared immunohistochemical expression in a series of p...

journal_title：American journal of clinical pathology

authors： Idirisinghe PK,Thike AA,Cheok PY,Tse GM,Lui PC,Fook-Chong S,Wong NS,Tan PH

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVES:Myeloid and lymphoid neoplasms with abnormalities of fibroblast growth factor receptor 1 gene (FGFR1) are a rare and aggressive disease group that harbors translocations of FGFR1 with at least 14 recognized partner genes. We report a case of a patient with a novel t(17;21)(p13;q22) with RUNX1 rearrangement a...

journal_title：American journal of clinical pathology

authors： Kumar KR,Chen W,Koduru PR,Luu HS

更新日期：2015-05-01 00:00:00

abstract：:Immunoperoxidase strains for prostate-specific antigen (PSA), prostatic acid phosphatase (PAcP), epithelial membrane antigen (EMA), and cytokeratins (MAK 6 and CK-KES) were performed on 1 case of squamous cell carcinoma of the prostate and on 13 cases of squamous metaplasia of prostatic epithelium in an effort to demo...

journal_title：American journal of clinical pathology

authors： Lager DJ,Goeken JA,Kemp JD,Robinson RA

更新日期：1988-11-01 00:00:00

abstract：:Remarkable improvements have been made in blood safety since the onset of the HIV epidemic. However, the current paradigm does not prevent all transfusion-transmitted infections and is reactive to new agents, thus accepting that some patients may be harmed before preventive measures are introduced. Several methods are...

journal_title：American journal of clinical pathology

authors： McCullough J

更新日期：2007-12-01 00:00:00

abstract：:Few cases of secondary CD5+ diffuse large B-cell lymphoma (DLBCL) that are not Richter syndrome have been reported previously. We report 9 cases of non-Richter syndrome secondary CD5+ DLBCL. Among 529 cases of DLBCL, 38 (7.2%) were CD5+ DLBCL, including 9 of secondary CD5+ DLBCL. Five cases gained CD5 expression durin...

journal_title：American journal of clinical pathology

authors： Maeshima AM,Taniguchi H,Nomoto J,Maruyama D,Kim SW,Watanabe T,Kobayashi Y,Tobinai K,Matsuno Y

更新日期：2009-03-01 00:00:00