Evaluation of real-time clinical decision support systems for platelet and cryoprecipitate orders.

abstract：:Diffuse alveolar damage (DAD) is usually considered a generalized lung process. During five years the authors observed 83 patients with generalized DAD in 827 adult autopsies (10.1%) and 10 patients with identical, but localized, lesions. The authors propose the term regional alveolar damage (RAD) to designate localiz...

journal_title：American journal of clinical pathology

authors： Yazdy AM,Tomashefski JF Jr,Yagan R,Kleinerman J

更新日期：1989-07-01 00:00:00

abstract：:Seventeen tubular carcinomas occurred among 211 consecutive mastectomies (7.6%). The relative frequencies of multicentric involvement in the ipsilateral breast (56%), history of bilateral mammary cancer (38%) (P less than .01), and family history of mammary cancer in a first-degree relative (40%) (P less than .05) wer...

journal_title：American journal of clinical pathology

authors： Lagios MD,Rose MR,Margolin FR

更新日期：1980-01-01 00:00:00

abstract：:This study evaluates the sensitivity and detection time of a new radiometric broth (BACTEC 13A medium, Johnston Laboratories, Towson, MD) designed for direct blood culturing for Mycobacteria. A total of 1,848 blood specimens were cultured in parallel by a new method in which blood was directly inoculated into 13A medi...

journal_title：American journal of clinical pathology

authors： Strand CL,Epstein C,Verzosa S,Effatt E,Hormozi P,Siddiqi SH

更新日期：1989-03-01 00:00:00

abstract：:Oxidized low-density lipoprotein (oxLDL)/beta(2)-glycoprotein I (beta2GPI) complexes have been implicated in atherogenesis. oxLDL/beta2GPI complexes were measured in 339 patients with suspected acute coronary syndromes. Approximately 68% had angiographically documented coronary artery disease (CAD) and significantly h...

journal_title：American journal of clinical pathology

authors： Greco TP,Conti-Kelly AM,Anthony JR,Greco T Jr,Doyle R,Boisen M,Kojima K,Matsuura E,Lopez LR

更新日期：2010-05-01 00:00:00

abstract：:Examination of kidneys of ten patients with uremia and severe hypertension treated by chronic intermittent hemodialysis revealed a deposition of glycogen within interstitial cells of the renal medulla. This is unlike any described renal distribution of glycogen. Electron microscopic studies performed in one case demon...

journal_title：American journal of clinical pathology

authors： Hughson MD,McManus JF,Fitts CT,Williams AV

更新日期：1979-09-01 00:00:00

abstract：:Our purpose was to determine whether the in vitro (or "spiked curve") method for the therapeutic heparin range is an accurate and valid method for heparin monitoring. Many laboratories use the in vitro method for determining the activated partial thromboplastin time (APTT)-based unfractionated heparin (UFH) therapeuti...

journal_title：American journal of clinical pathology

authors： Gausman JN,Marlar RA

更新日期：2011-06-01 00:00:00

abstract：:We optimized fluorogenic thrombin-generation assays with regard to sample volume, calibration, analytic corrections, and activation reagents. Lower sample volumes (40 vs 80 microL) were associated with better recovery of thrombin activity, lower interference due to absorbance of light, and higher total thrombin genera...

journal_title：American journal of clinical pathology

authors： Chandler WL,Roshal M

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:To investigate the clinicopathologic features of extranodal natural killer/T-cell lymphoma (ENKTL) not preceded by another Epstein-Barr virus (EBV)-related disorder in children and adolescents. METHODS:A series of 17 cases of ENKTL not preceded by another EBV-related disorder in children and adolescents in ...

journal_title：American journal of clinical pathology

authors： Huang Y,Xie J,Ding Y,Zhou X

更新日期：2016-01-01 00:00:00

abstract：:Uterine tumors with histologic resemblances to ovarian sex-cord tumors were encountered in 14 women in the fourth to sixth decades of life, most of whom had abnormal vaginal bleeding and enlarged uteri suggesting leiomyomas. The tumors in six cases (Group I) were identical to one or another form of well-recognized end...

journal_title：American journal of clinical pathology

authors： Clement PB,Scully RE

更新日期：1976-09-01 00:00:00

abstract：:Although the hematopoietic origin of mast cells is very probable, the cell from which they originate is still a matter of speculation. The description of "transitional basophil/mast cells" in myeloproliferative disorders has suggested a common origin for basophils and mast cells. In a case of mast cell transformation ...

journal_title：American journal of clinical pathology

authors： Gabriel LC,Escribano LM,Marie JP,Zittoun R,Navarro JL

更新日期：1986-08-01 00:00:00

abstract：Objectives:To determine whether V H family usage in B-cell lymphoproliferative disorders can be deduced from polymerase chain reaction (PCR) product-length information obtained through the BIOMED-2 (Invivoscribe, San Diego, CA) clonality assay. Methods:We develop an algorithm that uses the sizing information of the BI...

journal_title：American journal of clinical pathology

authors： McDonald TJ,Kuo L,Kuo FC

更新日期：2017-06-01 00:00:00

abstract：:Borrelia burgdorferi is difficult to detect in routine biopsy material from patients with skin lesions of borreliosis. In this study, a new immunohistochemical method, focus floating microscopy (FFM), was developed to detect B burgdorferi in tissue sections and was compared with polymerase chain reaction (PCR). By usi...

journal_title：American journal of clinical pathology

authors： Eisendle K,Grabner T,Zelger B

更新日期：2007-02-01 00:00:00

abstract：:Acute myeloid leukemia (AML) with isolated trisomy 4 is rare. Associations with KIT mutations on chromosome 4q12 have been documented. The clinicopathologic features and mutational status of KIT, FLT3, NPM1, CEBPA, and RAS were assessed in 13 AML cases with isolated trisomy 4. There were 9 men and 4 women with a media...

journal_title：American journal of clinical pathology

authors： Bains A,Lu G,Yao H,Luthra R,Medeiros LJ,Sargent RL

更新日期：2012-03-01 00:00:00

abstract：:To compare the Affirm VPIII molecular test (Becton Dickinson, Burlington, NC) with morphologic identification used in routine Papanicolaou (Pap) test screening in the detection and identification of Candida species, Trichomonas vaginalis, and Gardnerella vaginalis, we identified 431 cases with a concomitant Pap test a...

journal_title：American journal of clinical pathology

authors： Levi AW,Harigopal M,Hui P,Schofield K,Chhieng DC

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVES:To describe four cases of an uncommon type of acalculous cholecystitis/cholangitis characterized by increased intraepithelial lymphocytes within the biliary epithelium. METHODS:Cases were prospectively compiled during regular surgical pathology sign-out. Clinical information was obtained from the electronic...

journal_title：American journal of clinical pathology

authors： Jessurun J

更新日期：2015-01-01 00:00:00

abstract：:Mantle cell lymphoma (MCL) is characterized by typical morphologic features and the CD5+, CD23-immunophenotype. However, some morphologically typical MCLs are CD23+. A t(11;14)(q13;q32) translocation is frequently found in MCL, leading to overexpression of cyclin D1. We studied the expression of cyclin D1 in 50 small ...

journal_title：American journal of clinical pathology

authors： Peghini PE,Fehr J

更新日期：2002-02-01 00:00:00

abstract：:Immunohistochemical analysis, the most efficient way of assaying for HER-2/neu overexpression in patients with invasive breast cancer, is subject to variation in sensitivity and evaluation when used in multiple laboratories. Cell lines with differing but constant levels of HER-2/neu expression have been advocated as s...

journal_title：American journal of clinical pathology

authors： Rhodes A,Borthwick D,Sykes R,Al-Sam S,Paradiso A

更新日期：2004-07-01 00:00:00

abstract：:The visible absorption spectra of dilutions of commercially prepared chemistry control sera closely mimic those of jaundiced amniotic fluids in cases of fetal rhesus isoimmunization. The authors have assessed the use of these materials for the quality control of net absorbance measurements at 450 nm on amniotic fluids...

journal_title：American journal of clinical pathology

authors： McDonald OL,Watts MT

更新日期：1985-10-01 00:00:00

abstract：:After several transfusions with D-negative blood, an O Rh-negative women was apparently sensitized to the C and D antigens. In her prenatal workup, it became evident that she had in fact not been sensitized to D but to G, which initially appeared as anti-D plus anti-C. This sensitization pattern is an unusual occurren...

journal_title：American journal of clinical pathology

authors： Yesus YW,Akhter JE

更新日期：1985-12-01 00:00:00

abstract：:Fine-needle aspiration (FNA) is the standard of care for the initial workup of thyroid nodules, but there is no consensus algorithm to manage patients with benign results. We examined performance characteristics of initial and repeat satisfactory FNAs for all 402 patients who underwent thyroid surgery during a recent ...

journal_title：American journal of clinical pathology

authors： Flanagan MB,Ohori NP,Carty SE,Hunt JL

更新日期：2006-05-01 00:00:00

abstract：:The combined experience of four university medical centers with fine-needle aspiration biopsy (FNAB) of the mediastinum is reviewed. This series includes 189 cases, with 100 males and 89 females, 6 months to 86 years of age. The majority (71%) of diagnoses were neoplastic with the remainder equally distributed between...

journal_title：American journal of clinical pathology

authors： Powers CN,Silverman JF,Geisinger KR,Frable WJ

更新日期：1996-02-01 00:00:00

abstract：:During a three-year period, Staphylococcus aureus and Pseudomonas aeruginosa were the organisms most commonly isolated from blood cultures of burned children. Microorganisms were considered to contribute to the cause of death in 17 of 20 patients who died from various complications of thermal injuries. Pseudomonas aer...

journal_title：American journal of clinical pathology

authors： Smith RF,Linares HA,Jorgensen JH

更新日期：1975-04-01 00:00:00

abstract：OBJECTIVES:Universal screening of upper tract urothelial carcinoma (UTUC) for Lynch syndrome by mismatch repair (MMR) protein immunohistochemistry (IHC) has been recommended by some investigators. Herein, we assess this recommendation retrospectively by simulating its performance on a retrospective, unselected cohort o...

journal_title：American journal of clinical pathology

authors： Gayhart MG,Johnson N,Paul A,Quillin JM,Hampton LJ,Idowu MO,Smith SC

更新日期：2020-11-04 00:00:00

abstract：OBJECTIVES:To evaluate the predictive value of growth patterns in patients undergoing sorafenib treatment for metastatic clear cell renal cell carcinomas (CCRCCs). METHODS:Forty-eight patients were analyzed, each of whom underwent nephrectomy and received sorafenib treatment for metastatic CCRCC. Progression-free surv...

journal_title：American journal of clinical pathology

authors： Araki H,Tsuzuki T,Kimura T,Tanaka K,Yamada S,Sassa N,Yoshino Y,Hattori R,Gotoh M

更新日期：2015-04-01 00:00:00

abstract：:The role of the HER2 receptor remains uncertain in the pathogenesis and progression of human prostate cancer. Previous studies have reported widely divergent rates for HER2 expression in primary prostate tumors, probably owing to significant methodologic differences in the studies. Few data exist about the frequency o...

journal_title：American journal of clinical pathology

authors： Reese DM,Small EJ,Magrane G,Waldman FM,Chew K,Sudilovsky D

更新日期：2001-08-01 00:00:00

abstract：:The diagnostic expert system for colonic lesions (DESCL) was designed to discriminate colonic adenoma and adenocarcinoma from normal colonic tissue. Although it was originally developed for use in conjunction with a machine vision analytic system, the DESCL has evolved into a teaching tool and a model for conceptual m...

journal_title：American journal of clinical pathology

authors： Graham AR,Paplanus SH,Bartels PH

更新日期：1990-10-01 00:00:00

abstract：:We compared the anti-estrogen receptors (ER) SP1, 6F11, and 1D5 antibodies in breast carcinoma cases with different ranges of positive cells to evaluate whether this could generate different therapies for patients. We selected 66 cases of breast cancer, each of which was immunostained with the 3 antibodies. 1D5 was le...

journal_title：American journal of clinical pathology

authors： Bogina G,Zamboni G,Sapino A,Bortesi L,Marconi M,Lunardi G,Coati F,Massocco A,Molinaro L,Pegoraro C,Venturini M

更新日期：2012-11-01 00:00:00

abstract：:Apocrine carcinoma (AC) is an uncommon, poorly characterized type of breast tumor. In this review, 55 patients with intraductal (ID) AC and 17 patients with infiltrating (IF) AC were analyzed retrospectively to define the histologic features and clinical course of this neoplasm. Recurrences in the breast occurred in 3...

journal_title：American journal of clinical pathology

authors： Abati AD,Kimmel M,Rosen PP

更新日期：1990-10-01 00:00:00

abstract：:Breast cancer is the result of a multistage carcinogenic process. Initiation, promotion, dependency and autonomy make up a sequence of experimentally distinguishable phases of this process. Progression--the transition from dependency on hormonal support to autonomy--is demonstrable clinically. High-affinity saturatabl...

journal_title：American journal of clinical pathology

authors： Brennan MJ

更新日期：1975-12-01 00:00:00

abstract：OBJECTIVES:To assess physicians' and nurses' satisfaction with the service provided by the laboratory at Gondar University Hospital. METHODS:We conducted a cross-sectional study involving 196 nurses and physicians. RESULTS:Overall level of satisfaction was 51.1% for nurses and 51.5% for physicians. Lack of consistenc...

journal_title：American journal of clinical pathology

authors： Addis Z,Birhan W,Derseh D,Sahle B,Gizaw N

更新日期：2013-09-01 00:00:00