HER2 protein expression and gene amplification in androgen-independent prostate cancer.

abstract：OBJECTIVES:Fundic gland polyps (FGPs) occur in two clinical settings, sporadic and syndromic. Epithelial dysplasia is rare in sporadic FGPs, and progression data from large series are lacking. The aim of this study was to evaluate the clinical, morphologic, and immunohistochemical features in a large series of sporadic...

journal_title：American journal of clinical pathology

authors： Levy MD,Bhattacharya B

更新日期：2015-10-01 00:00:00

abstract：:DRC (dendritic reticulum cell) antigen expression was studied in 38 cases of B-cell lymphomas including follicular lymphoma. The results of this study showed DRC-1 to be expressed in 1/3 of small lymphocytic; 3/3 of mantle zone lymphoma (MZL); 10/10 of follicular, small cleaved; 6/7 of follicular, mixed; 1/2 of follic...

journal_title：American journal of clinical pathology

authors： Mori N,Oka K,Kojima M

更新日期：1988-04-01 00:00:00

abstract：:Adenomatous polyps are common neoplastic lesions of the large intestine. The risk of carcinoma increases with polyp size. Small polyps are typically totally embedded for histologic examination, but no standard method for sampling large, grossly benign polyps has been established. We reviewed grossly noninvasive adenom...

journal_title：American journal of clinical pathology

authors： Euscher ED,Niemann TH,Lucas JG,Kurokawa AM,Frankel WL

更新日期：2001-09-01 00:00:00

abstract：:To compare the Affirm VPIII molecular test (Becton Dickinson, Burlington, NC) with morphologic identification used in routine Papanicolaou (Pap) test screening in the detection and identification of Candida species, Trichomonas vaginalis, and Gardnerella vaginalis, we identified 431 cases with a concomitant Pap test a...

journal_title：American journal of clinical pathology

authors： Levi AW,Harigopal M,Hui P,Schofield K,Chhieng DC

更新日期：2011-03-01 00:00:00

abstract：:We studied the role of ischemia-modified albumin (IMA) with standard biomarkers (myoglobin, creatine kinase-MB [CK-MB], troponin I [TnI]) in assessment of 200 patients with suspected myocardial ischemia admitted to the emergency department. Every case was reviewed by a cardiologist. A clinical diagnosis of ischemia wa...

journal_title：American journal of clinical pathology

authors： Anwaruddin S,Januzzi JL Jr,Baggish AL,Lewandrowski EL,Lewandrowski KB

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES:GATA3 is a transcription factor regulating luminal cell differentiation in the mammary glands and has been implicated in the luminal types of breast carcinoma. The prognostic significance of GATA3 in breast cancer remains controversial. METHODS:In this study, we assessed the prognostic value of the molecule...

journal_title：American journal of clinical pathology

authors： McCleskey BC,Penedo TL,Zhang K,Hameed O,Siegal GP,Wei S

更新日期：2015-11-01 00:00:00

abstract：:Oxidized low-density lipoprotein (oxLDL)/beta(2)-glycoprotein I (beta2GPI) complexes have been implicated in atherogenesis. oxLDL/beta2GPI complexes were measured in 339 patients with suspected acute coronary syndromes. Approximately 68% had angiographically documented coronary artery disease (CAD) and significantly h...

journal_title：American journal of clinical pathology

authors： Greco TP,Conti-Kelly AM,Anthony JR,Greco T Jr,Doyle R,Boisen M,Kojima K,Matsuura E,Lopez LR

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVES:The National Cancer Institute (NCI) National Clinical Trials Network performs phase II and III clinical trials, which increasingly rely on the submission of diagnostic formalin-fixed, paraffin-embedded tissue blocks for biomarker assessment. Simultaneously, advances in precision oncology require that clinica...

journal_title：American journal of clinical pathology

authors： Makhlouf H,Watson MA,Lankes HA,Weil C,Dickler M,Birrer M,Moskaluk C,Ramirez NC,Okby N,Alonsozana E,Barnes M,Goldman EB,Enos R,Lubensky I

更新日期：2020-01-02 00:00:00

abstract：:Pseudo-Pelger-Huët anomaly (PPHA) has been documented in association with transplant medications and other drugs. This iatrogenic neutrophilic dysplasia is reversible with cessation or adjustment of medications but is frequently confused with myelodysplastic syndrome (MDS) based on the conventional concept that PPHA i...

journal_title：American journal of clinical pathology

authors： Wang E,Boswell E,Siddiqi I,Lu CM,Sebastian S,Rehder C,Huang Q

更新日期：2011-02-01 00:00:00

abstract：:One of the functions of von Willebrand factor (vWF) is to serve as a carrier of clotting factor VIII (FVIII). Deficiency of this function results in the von Willebrand disease (vWD) variant type 2N, which resembles hemophilia A. We describe a new sandwich enzyme-linked immunosorbent assay (ELISA) to study the ability ...

journal_title：American journal of clinical pathology

authors： Casonato A,Pontara E,Zerbinati P,Zucchetto A,Girolami A

更新日期：1998-03-01 00:00:00

abstract：:A clinically and histopathologically well-documented case of malignant carcinoid tumor (with carcinoid syndrome) is described. The presence of numerous psammoma bodies in metastatic carcinoid tumor deposits, confirmed by histochemical and ultrastructural analyses, represents a heretofore unreported finding. ...

journal_title：American journal of clinical pathology

authors： Caya JG,Tieu TM,Wollenberg NJ,Soergel K,Anderson T

更新日期：1984-03-01 00:00:00

abstract：:We sought to determine the sensitivity and specificity of immunohistochemistry using the TORDJI-22 MoAb (BioGenex, San Ramon, Calif), which is specific for the C-100 protein of the hepatitis C virus, compared with reverse transcriptase-polymerase chain reaction (RT-PCR) of tissue for viral RNA. RT-PCR had been perform...

journal_title：American journal of clinical pathology

authors： Brody RI,Eng S,Melamed J,Mizrachi H,Schneider RJ,Tobias H,Teperman LW,Theise ND

更新日期：1998-07-01 00:00:00

abstract：:The major histocompatibility complex probably plays a crucial role in the efficacy of the cellular immune response against virally infected cervical diseases. Therefore, the allele-specific histocompatibility-related leukocyte antigens (HLA) class I and II expression on normal (n = 10), premalignant (n = 25), and mali...

journal_title：American journal of clinical pathology

authors： Hilders CG,Houbiers JG,Krul EJ,Fleuren GJ

更新日期：1994-01-01 00:00:00

abstract：:Studies from Africa have demonstrated that black people have higher vitamin B12 (cobalamin) levels than do white people. The authors compared healthy white people, black people, and Latin-Americans in the United States. Their study is also the largest in which the effect of race and sex on the cobalamin levels has bee...

journal_title：American journal of clinical pathology

authors： Saxena S,Carmel R

更新日期：1987-07-01 00:00:00

abstract：:We compared the differential counts of normal and abnormal bone marrow from touch imprints with those from aspirate smears to determine whether the touch imprint was reliable for independent routine use in the examination of bone marrow and the classification of hematologic abnormalities. Normocellular bone marrow spe...

journal_title：American journal of clinical pathology

authors： Aboul-Nasr R,Estey EH,Kantarjian HM,Freireich EJ,Andreeff M,Johnson BJ,Albitar M

更新日期：1999-06-01 00:00:00

abstract：:Infusible platelet membranes (IPMs) prepared from fresh or outdated human platelets have been shown to correct prolonged bleeding times in thrombocytopenic rabbits. In previous trials, IPMs did not seem to be immunogenic and lacked dose-limiting toxicity. The present study was undertaken to explore whether the platele...

journal_title：American journal of clinical pathology

authors： Graham SS,Gonchoroff NJ,Miller JL

更新日期：2001-01-01 00:00:00

abstract：:The Laboratory Proficiency Testing Program has been in effect for 20 years. During the past 6 years, samples were distributed for screening, investigation, and identification of hemoglobinopathies to test laboratory proficiency. Six samples for hemoglobin (Hb) S screening were distributed to from 37 to 163 laboratorie...

journal_title：American journal of clinical pathology

authors： Lafferty J,Ali MA,Carstairs K,Crawford L

更新日期：1997-05-01 00:00:00

abstract：:The expression of human E-cadherin in normal tissues and in benign and malignant tumors of female genital organs was examined immunohistochemically with a monoclonal antibody, HECD-1, specific for human E-cadherin. The normal tissues included the ovary, fallopian tube, uterine endometrium, uterine cervix, and vagina. ...

journal_title：American journal of clinical pathology

authors： Inoue M,Ogawa H,Miyata M,Shiozaki H,Tanizawa O

更新日期：1992-07-01 00:00:00

abstract：:The evaluation of quality control (QC) practices from the College of American Pathologists (CAP) Microbiology Surveys demonstrates a trend away from daily controls similar to that first noted in 1980. Previous recommendations for more relevant cost-containment oriented weekly QC procedures are discussed, and the 1982 ...

journal_title：American journal of clinical pathology

authors： Jones RN,Edson DC,Gilmore BF

更新日期：1983-10-01 00:00:00

abstract：:The authors have examined the cellular distribution of lipocortin-1 (L-1) in the normal and diseased central nervous system (CNS) using the peroxidase-antiperoxidase (PAP) technique with a polyclonal antibody specific for L-1. L-1 immunoreactivity was evaluated in the frontal cortex, parahippocampal gyrus/lateral vent...

journal_title：American journal of clinical pathology

authors： Johnson MD,Kamso-Pratt JM,Whetsell WO Jr,Pepinsky RB

更新日期：1989-10-01 00:00:00

abstract：:The authors studied the effect of averaging replicated assays of Factor IX coagulation activity and Factor IX antigen on each plasma specimen in improving the ability to detect carriers of hemophilia B. The improvement resulting from this procedure is particularly marked in tests depending on the linear regression of ...

journal_title：American journal of clinical pathology

authors： Lipworth L,Tiarks CY,Rice CA,Pechet L

更新日期：1979-12-01 00:00:00

abstract：:An anti-serum against human neuron-specific enolase (NSE), raised in sheep, has been characterized and used for immunocytochemical localization of NSE in paraffin sections of normal tissues and lung cancers. Of the small cell carcinomas (SCC), 69 out of 99 (70%) cases stained with the anti-serum. Maltreated biopsies s...

journal_title：American journal of clinical pathology

authors： Bergh J,Esscher T,Steinholtz L,Nilsson K,Påhlman S

更新日期：1985-07-01 00:00:00

abstract：:The uptake and storage of 5-hydroxytryptamine by human platelets from normal donors and patients with the carcinoid syndrome are reported. When platelets were incubated in the presence of 3H-5-hydroxytryptamine (50 microM), an initial phase of rapid uptake was observed until 5-hydroxytryptamine levels of 1--2 microgra...

journal_title：American journal of clinical pathology

authors： Lewis JC,Moertel CG

更新日期：1978-10-01 00:00:00

abstract：:The use of rapid, simple tests to detect antibodies to human immunodeficiency virus (HIV) in urine could be valuable for several testing situations, such as in private offices, for epidemiologic surveys, and in developing countries. The authors evaluated the performance of the SUDS HIV type 1 test to detect antibody t...

journal_title：American journal of clinical pathology

authors： Constantine NT,Zhang X,Li L,Bansal J,Hyams KC,Smialek JE

更新日期：1994-02-01 00:00:00

abstract：OBJECTIVES:In 2001, the University of New Mexico Hospitals implemented a rapid screening tool for the triage of suspected hantavirus cardiopulmonary syndrome based on peripheral blood smear morphology. Five criteria guided clinical decisions: thrombocytopenia, hemoconcentration, granulocytic left shift, absence of toxi...

journal_title：American journal of clinical pathology

authors： Dvorscak L,Czuchlewski DR

更新日期：2014-08-01 00:00:00

abstract：:Hemizygous TP53 gene deletion is the most important adverse risk factor in chronic lymphocytic leukemia (CLL), but its relationship with p53 protein expression is unclear. We investigated 110 CLL cases and correlated nuclear p53 protein immunoreactivity with TP53 gene deletion status and other CLL-associated genetic r...

journal_title：American journal of clinical pathology

authors： Chang H,Jiang AM,Qi CX

更新日期：2010-01-01 00:00:00

abstract：:Transbronchoscopic biopsies of lung (transbronchial) or bronchus (endobronchial) have a high diagnostic of yield when performed by a single expert bronchoscopist or a small group of expert bronchoscopists. This procedure's diagnostic yield was evaluated in a general hospital where biopsies are performed by a diverse g...

journal_title：American journal of clinical pathology

authors： Jenkins R,Myerowitz RL,Kavic T,Slasky S

更新日期：1979-12-01 00:00:00

abstract：:Minimal inhibitory concentrations (MICs) of clindamycin, cefoxitin, imipenem, and metronidazole were determined by the E-Test and a reference agar dilution method for 92 gram-negative anaerobic organisms. For 335 MIC pairs, the agreement between the two systems was 80.1%; 60 (17.9%) differed by two or more twofold dil...

journal_title：American journal of clinical pathology

authors： Couroux PR,Massey VE,Schieven BC,Lannigan R,Hussain Z

更新日期：1993-09-01 00:00:00

abstract：:Terminal deoxynucleotidyl transferase (TdT) is a marker of lymphoblastic disorders. Previously, the technique for determining TdT on smears was by indirect immunofluorescence. An immunoperoxidase procedure for detecting TdT on smears is reported. Results are in a comparable range with the indirect immunofluorescent te...

journal_title：American journal of clinical pathology

authors： Stass SA,Dean L,Peiper SC,Bollum FJ

更新日期：1982-02-01 00:00:00

abstract：:Utilization of nonconventional bacterial strains and electron microscopy occasionally may aid in the recognition of unusual microorganisms which fail to be demonstrated by more conventional bacterial stains. We report an unusual case of recurrent vaginal polyps, initially thought by physical examination to represent a...

journal_title：American journal of clinical pathology

authors： Strate SM,Taylor WE,Forney JP,Silva FG

更新日期：1983-05-01 00:00:00