Laboratory prediction of the carrier state in hemophilia B: role of replication of assays.

abstract：:Specific esterase activity, a property generally ascribed to cells of granulocytic origin, was found in abnormal erythroid precursors obtained from the bone marrows of six patients with untreated erythroleukemia. These erythroblasts also showed nonspecific esterase activity. Neither specific nor nonspecific esterase a...

journal_title：American journal of clinical pathology

authors： Kass L

更新日期：1977-04-01 00:00:00

abstract：:A unilateral multicystic mass in the connective tissue adjacent to the vas deferens in a 46-year-old man is reported. Anatomically, it was distinct from the epididymis and vas and contained no sperm. The epithelial lining was simple, ciliated, and cuboidal to columnar. The cysts were surrounded by connective tissue co...

journal_title：American journal of clinical pathology

authors： Schned AR,Seremetis GM,Rous SN

更新日期：1994-04-01 00:00:00

abstract：:The authors report a case of primary Ki-1 lymphoma of the brain. The patient was a 4 1/2-year-old black girl who presented with a 4- and 5-day history of headaches, nausea, vomiting, neck stiffness, and difficulty in walking. Computed tomography (CT) scan of the brain showed two discrete densities in the left occipita...

journal_title：American journal of clinical pathology

authors： Havlioglu N,Manepalli A,Galindo L,Sotelo-Avila C,Grosso L

更新日期：1995-04-01 00:00:00

abstract：:Acute toxic hepatic necrosis is common and may be fatal. Predicting clinical outcome may be aided by following serum markers that could indicate recovery or may signify massive (substantial) destruction of functional liver mass. Previously, in a published case of chloroform poisoning, we serially assayed serum biomark...

journal_title：American journal of clinical pathology

authors： Horn KD,Wax P,Schneider SM,Martin TG,Nine JS,Moraca MA,Virji MA,Aronica PA,Rao KN

更新日期：1999-09-01 00:00:00

abstract：:We investigated the pathologic significance of ductular reactions in chronic liver diseases with respect to cellular senescence. The expression of senescence-associated markers (p16(INK4a) and p21(WAF1/Cip1)), cell proliferation, cell cycle markers (cyclin D and cyclin A), and neural cell adhesion molecule (NCAM) was ...

journal_title：American journal of clinical pathology

authors： Sasaki M,Ikeda H,Yamaguchi J,Miyakoshi M,Sato Y,Nakanuma Y

更新日期：2010-02-01 00:00:00

abstract：:Reported is a case of lymphoma which was preceded for nine years by an apparently reactive lymphadenopathy. Original slides of the multiple lymphoid tissue samples are reviewed, with emphasis on the gradually increasing numbers of mitoses, atypical histiocytes, and eosinophils, suggestive of malignant transformation. ...

journal_title：American journal of clinical pathology

authors： Hyland CH,Murad TM,Dismukes WE

更新日期：1977-11-01 00:00:00

abstract：:In view of their reported reciprocal effects on apoptosis, the expression of p53 and bcl-2 proteins was studied in 46 cases of Hodgkin's disease by immunocytochemical labeling. We found p53 protein in Reed-Sternberg cells and their mononuclear variants in 16 of the 46 cases (34.7%) of Hodgkin's disease, mainly in a nu...

journal_title：American journal of clinical pathology

authors： Doussis IA,Pezzella F,Lane DP,Gatter KC,Mason DY

更新日期：1993-06-01 00:00:00

abstract：:Two patients with sporadic primary hyperparathyroidism were found to harbor tiny medullary thyroid carcinomas. In addition, parafollicular-cell hyperplasia was recognized in one of these thyroids by the use of immunoperoxidase stain to localize calcitonin. The possible relationships between these lesions are discussed...

journal_title：American journal of clinical pathology

authors： Livolsi VA,Feind CR

更新日期：1979-05-01 00:00:00

abstract：:In 10 cases of Barrett adenocarcinoma, samples from 8 tumor areas (including superficial and deep from peripheral and central areas) and a regional lymph node metastasis were studied for amplification of c-myc, c-erbB-2, and EGFR. We analyzed loss of heterozygosity (LOH) at 3 loci (APC, MCC, and RB) and 2 anonymous mi...

journal_title：American journal of clinical pathology

authors： Owonikoko T,Rees M,Gabbert HE,Sarbia M

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVES:Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) is a heterogeneous disorder defined by morphologic, genetic, or clinical features. Genetic abnormalities associated with AML-MRC are often associated with adverse prognostic features, and many cases are preceded by a myelodysplastic syndrom...

journal_title：American journal of clinical pathology

authors： Vardiman J,Reichard K

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVES:To correlate human herpesvirus 6 (HHV-6) viral load with pathologic features in graft acute hepatitis of unknown origin. METHODS:Liver frozen samples from 26 patients with graft hepatitis of unknown origin were available for HHV-6 DNA quantification. RESULTS:In 10 (38.5%) of 26 liver samples, HHV-6 DNA was...

journal_title：American journal of clinical pathology

authors： Buyse S,Roque-Afonso AM,Vaghefi P,Gigou M,Dussaix E,Duclos-Vallée JC,Samuel D,Guettier C

更新日期：2013-09-01 00:00:00

abstract：:Five hundred consecutive isolates of viridans streptococci were identified to the species level in an effort to determine their distribution and incidence in routine clinical specimens. Viridans streptococci accounted for significant percentages of streptococcal isolates from urine, wounds, body fluids, and blood. The...

journal_title：American journal of clinical pathology

authors： Ruoff KL,Fishman JA,Calderwood SB,Kunz LJ

更新日期：1983-12-01 00:00:00

abstract：:Fine-needle cytology (FNC) of 292 palpable orbital and eyelid tumors was performed with a 25-gauge (0.5-mm), 3-cm needle and compared with the histopathologic findings in 286 cases. Among these 286 cases, a concordant diagnosis of malignancy and type was achieved in 249 cases (87%). False positive diagnoses were made ...

journal_title：American journal of clinical pathology

authors： Zajdela A,Vielh P,Schlienger P,Haye C

更新日期：1990-01-01 00:00:00

abstract：:A case is presented of an anterior mediastinal mass arising in a 64-year-old woman that showed on histologic, immunopathologic, and ultra-structural examination features of a poorly differentiated (insular) thyroid carcinoma. The tumor in this patient most likely arose from ectopically displaced thyroid tissue on the ...

journal_title：American journal of clinical pathology

authors： Dominguez-Malagon H,Guerrero-Medrano J,Suster S

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVES:To evaluate the clinical utility of and demand for the creatine kinase (CK)-MB assay. METHODS:We examined the number of CK-MB tests from 2007 through 2013 while we progressively deemphasized their use. We first removed CK-MB from the acute coronary syndrome (ACS) panel and then from the main menu and observ...

journal_title：American journal of clinical pathology

authors： Singh G,Baweja PS

更新日期：2014-03-01 00:00:00

abstract：:A method using the RNA polymerase chain reaction technique to diagnose infection retrospectively using single-stranded RNA enteroviruses in paraffin-embedded tissue blocks is reported. This method takes advantage of extreme sequence conservation in the 5' untranslated region of the enteroviral genome and uses two roun...

journal_title：American journal of clinical pathology

authors： Redline RW,Genest DR,Tycko B

更新日期：1991-11-01 00:00:00

abstract：:High-performance liquid chromatography (HPLC) is replacing electrophoresis for identification of hemoglobin variants. Our objective was to identify unknown tall peaks with elution times and shapes of hemoglobin Barts found on hemoglobin chromatograms that could not be confirmed by alkaline and acid gel electrophoresis...

journal_title：American journal of clinical pathology

authors： Howanitz PJ,Kozarski TB,Howanitz JH,Chauhan YS

更新日期：2006-04-01 00:00:00

abstract：:Results of a comparison of the diagnostic efficacy of percutaneous needle biopsy of the parietal pleura with that of cytologic examination of pleural fluid sediment obtained concurrently from 166 patients with benign or cancerous pleural disorders are reported. Of 44 patients with confirmatory evidence of cancer invol...

journal_title：American journal of clinical pathology

authors： Frist B,Kahan AV,Koss LG

更新日期：1979-07-01 00:00:00

abstract：:This is apparently the second report of a case of human meningoencephalitis caused by the nematode Micronema deletrix. The patient had severe granulomatous meningoencephalitis with numerous foci of hemorrhage and encephalomalacia. Numerous adult female and larval M. deletrix were in the brain. The organisms probably i...

journal_title：American journal of clinical pathology

authors： Shadduck JA,Ubelaker J,Telford VQ

更新日期：1979-10-01 00:00:00

abstract：:This paper presents the first comprehensive morphometry analysis of normal thyroid, adenomas, and follicular and papillary carcinomas. The mean nuclear volume and the mean nuclear surface increased, while the volume densities of rough endoplasmic reticulum and dense bodies decreased from normal thyroid through adenoma...

journal_title：American journal of clinical pathology

authors： Johannessen JV,Sobrinho-Simóes M,Finseth I,Pilström L

更新日期：1983-02-01 00:00:00

abstract：:To study the distribution and thromboembolic effect of Ultrafluid Lipiodol, 15 surgically removed hepatocellular carcinomas with selective intraarterial Lipiodol injection 7 to 10 days before surgery and 15 noninjected controls were studied radiologically and histologically. Tissue blocks were processed with an en blo...

journal_title：American journal of clinical pathology

authors： Arnold MM,Kreel L,Wallace AC,Li AK

更新日期：1992-03-01 00:00:00

abstract：:A case of epithelioid sarcoma in a 39-year-old woman who had metastatic lesions in her lung from a primary arm tumor is presented. A review of the literature and analysis of this case did not identify any specific light microscopic or immunohistochemical way to separate definitively the lung cytologic smear in this ca...

journal_title：American journal of clinical pathology

authors： Niemann TH,Bottles K

更新日期：1993-08-01 00:00:00

abstract：:The authors describe two patients with clinically and histopathologically documented advanced (tumor) stage mycosis fungoides. In each case the large, pleomorphic neoplastic cells lacked the monoclonal antibody-defined cell surface antigens commonly associated with immature and mature T-cells, i.e., T11, Leu-1, T3, T4...

journal_title：American journal of clinical pathology

authors： Wieczorek R,Suhrland M,Ramsay D,Reed ML,Knowles DM 2nd

更新日期：1986-07-01 00:00:00

abstract：:We report an unusual case of acinar cell cystadenoma of the pancreas in a 52-year-old man treated for pulmonary adenocarcinoma. The lesion, located in the body of the pancreas, was revealed incidentally by abdominal computed tomography during follow-up for a pulmonary neoplasm. A left pancreatectomy was performed. The...

journal_title：American journal of clinical pathology

authors： Chatelain D,Paye F,Mourra N,Scoazec JY,Baudrimont M,Parc R,Flejou JF

更新日期：2002-08-01 00:00:00

abstract：:Acute exacerbations of idiopathic pulmonary fibrosis/cryptogenic fibrosing alveolitis (IPF/CFA) are rare and typically terminal events, but their relationship to underlying patterns of idiopathic interstitial pneumonias is unknown. We reviewed autopsy material from patients who died of diffuse alveolar damage in the c...

journal_title：American journal of clinical pathology

authors： Rice AJ,Wells AU,Bouros D,du Bois RM,Hansell DM,Polychronopoulos V,Vassilakis D,Kerr JR,Evans TW,Nicholson AG

更新日期：2003-05-01 00:00:00

abstract：Objectives:Fibromatosis of the breast is an uncommon neoplasm with potential for local recurrence. Treatment has traditionally been surgical excision with current trends toward conservative management. Given the option of observation after diagnosis by core needle biopsy (CNB), we sought to evaluate the accuracy of CNB...

journal_title：American journal of clinical pathology

authors： Kuba MG,Lester SC,Giess CS,Bertagnolli MM,Wieczorek TJ,Brock JE

更新日期：2017-09-01 00:00:00

abstract：:The results obtained with eight pregnancy kits on 735 urines were compared. Overall accuracies were similar and fairly high (93.4 to 95.37%), although only 78.28% of all pregnancies were simultaneously detected by all eight kits. It is suggested that the different performances of each kit could be accounted for not on...

journal_title：American journal of clinical pathology

authors： Porres JM,D'Ambra C,Lord D,Garrity F

更新日期：1975-10-01 00:00:00

abstract：:Using Venn diagrams derived from set theory, a mathematic model is presented that allows triple-label immunophenotypic analysis of cells based upon double-label measurements. Practical applications of this method are illustrated and discussed. Using this model, triple-label data concerning Leu-8 and Leu-9 (CD7) antige...

journal_title：American journal of clinical pathology

authors： Wood GS

更新日期：1989-07-01 00:00:00

abstract：:Utilization of nonconventional bacterial strains and electron microscopy occasionally may aid in the recognition of unusual microorganisms which fail to be demonstrated by more conventional bacterial stains. We report an unusual case of recurrent vaginal polyps, initially thought by physical examination to represent a...

journal_title：American journal of clinical pathology

authors： Strate SM,Taylor WE,Forney JP,Silva FG

更新日期：1983-05-01 00:00:00

abstract：:Mechanical release of single cell suspensions from solid tumors for DNA analysis by flow cytometry has been shown to be optimal for adenocarcinomas in general. In the breast, many adenocarcinomas are fibrotic or scirrhous, creating difficulty in separating the neoplastic cells from the stroma. The authors have conduct...

journal_title：American journal of clinical pathology

authors： Torres FX,Mackowiak PG,Brown RD,Linden MD,Zarbo RJ

更新日期：1995-01-01 00:00:00