New developments in prenatal screening for Down syndrome.

abstract：:A tumor of the larynx composed of a small infiltrating and well-differentiated squamous cell carcinoma and a large polypoid sarcomatous mass showing the histologic features of the malignant giant cell tumor of soft parts (MGCT) is reported. Other types of sarcomatous components have been described with squamous cell c...

journal_title：American journal of clinical pathology

authors： Alguacil-Garcia A,Alonso A,Pettigrew NM

更新日期：1984-09-01 00:00:00

abstract：:The quality management program in the Division of Transfusion Medicine at our institution had evolved to the point that the program generally was perceived to be the sole responsibility of our Quality Unit (which was administratively independent of day-to-day operations). It became clear that this administrative model...

journal_title：American journal of clinical pathology

authors： Foss ML,Moore SB

更新日期：2005-10-01 00:00:00

abstract：:Five patterns of bone marrow infiltration by non-Hodgkin lymphoma or Hodgkin lymphoma are currently recognized, but a true follicular pattern of bone marrow involvement by follicular lymphoma has not been described. In 260 bone marrow trephine biopsy specimens involved by follicular lymphoma, we identified 12 cases wi...

journal_title：American journal of clinical pathology

authors： Torlakovic E,Torlakovic G,Brunning RD

更新日期：2002-11-01 00:00:00

abstract：:The probabilities of low transferrin saturation, folic acid, or vitamin B12 levels in association with various erythrocyte indices was determined from the prevalences of these abnormalities and the distributions of the indices among 206 hospitalized and 1,000 ambulatory anemic patients. At mean corpuscular hemoglobin ...

journal_title：American journal of clinical pathology

authors： Griner PF,Oranburg PR

更新日期：1978-11-01 00:00:00

abstract：:Cytologic features of the cell-stroma interface are useful in distinguishing between monomorphic adenomas of the basal cell type and adenoid cystic carcinoma. In basal cell adenomas, the collagenous stroma interdigitates with adjacent cells, whereas in adenoid cystic carcinoma, the two are separated by a sharp smooth ...

journal_title：American journal of clinical pathology

authors： Stanley MW,Horwitz CA,Rollins SD,Powers CN,Bardales RH,Korourain S,Stern SJ

更新日期：1996-07-01 00:00:00

abstract：:The role of fine-needle aspiration (FNA) in the diagnosis of breast carcinoma is established. We evaluated whether the degree of cellular dyscohesion and the nuclear grade in FNA material of breast carcinomas are reliable prognostic predictors for ipsilateral axillary lymph node metastasis. FNA specimens from 98 women...

journal_title：American journal of clinical pathology

authors： Schiller AB,Tadros TS,Birdsong GG,Grossl NA

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVES:To compare next-generation sequencing (NGS) platforms with mutation-specific analysis platforms in a clinical setting, in terms of sensitivity, mutation specificity, costs, capacity, and ease of use. METHODS:We analyzed 25 formalin-fixed, paraffin-embedded lung cancer samples of different size and tumor per...

journal_title：American journal of clinical pathology

authors： Hinrichs JW,van Blokland WT,Moons MJ,Radersma RD,Radersma-van Loon JH,de Voijs CM,Rappel SB,Koudijs MJ,Besselink NJ,Willems SM,de Weger RA

更新日期：2015-04-01 00:00:00

abstract：:Using digital cell image analysis performed on Feulgen-stained nuclei, the nuclear characteristics of prostatic neoplasia, ranging from benign (benign prostatic hyperplasia [BPH]), through dysplastic (prostatic intraepithelial neoplasia [PIN] 1-3), to carcinoma were studied. Four histopathologic groups were studied: g...

journal_title：American journal of clinical pathology

authors： Petein M,Michel P,van Velthoven R,Pasteels JL,Brawer MK,Davis JR,Nagle RB,Kiss R

更新日期：1991-11-01 00:00:00

abstract：:Neoplastic transformation of epithelial cell sis commonly associated with altered synthesis of mucin glycoproteins. Few studies have been performed on the correlation between MUC 1 expression and pancreatic carcinoma using immunohistochemical methods. We compared the patterns of MUC 1 expression in normal pancreatic t...

journal_title：American journal of clinical pathology

authors： Monges GM,Mathoulin-Portier MP,Acres RB,Houvenaeghel GF,Giovannini MF,Seitz JF,Bardou VJ,Payan MJ,Olive D

更新日期：1999-11-01 00:00:00

abstract：:We studied the expression of cytokeratin (CK) 7, CK20, CDX-2, and p16 in 119 cervical adenocarcinomas (65 usual type [50 invasive; 15 in situ], 37 intestinal type [21 invasive; 16 in situ], 10 endometrioid, 5 adenosquamous, and 2 signet-ring carcinomas) in comparison with 55 cases of rectal adenocarcinomas. The percen...

journal_title：American journal of clinical pathology

authors： Saad RS,Ismiil N,Dubé V,Nofech-Mozes S,Khalifa MA

更新日期：2009-10-01 00:00:00

abstract：:Carumonam, a new monobactam, was found to have an anti-microbial spectrum similar to aztreonam. Its spectrum includes Enterobacteriaceae, Haemophilus influenzae, pathogenic Neisseria species, Pseudomonas aeruginosa, and some streptococci. Staphylococcus species, enterococci, and many other nonenteric gram-negative bac...

journal_title：American journal of clinical pathology

authors： Jones RN,Barry AL,Thornsberry C,Fuchs PC,Packer RR

更新日期：1986-11-01 00:00:00

abstract：:Because of the demonstrated efficacy of Leu-M1 as a discriminant between malignant epithelioid mesothelioma (MEM) and adenocarcinomas involving the serosal surfaces (ACSs), the authors assessed the reactivities of related "myelomonocytic" antigens in this context. Paraffin sections from 41 MEMs and 43 ACSs (pulmonary,...

journal_title：American journal of clinical pathology

authors： Wick MR,Mills SE,Swanson PE

更新日期：1990-07-01 00:00:00

abstract：:Serologic testing shows that hepatitis C virus (HCV) may have a role in the pathogenesis of B-cell non-Hodgkin lymphomas (B-cell NHLs). We tried to demonstrate HCV RNA sequences in paraffin-embedded tissue from B-cell NHLs by reverse-transcription double polymerase chain reaction (RT-PCR) and Southern blotting. We stu...

journal_title：American journal of clinical pathology

authors： Karavattathayyil SJ,Kalkeri G,Liu HJ,Gaglio P,Garry RF,Krause JR,Dash S

更新日期：2000-03-01 00:00:00

abstract：:The thymus was the site of a true histiocytic lymphoma. Immunohistochemical demonstration of lysozyme and alpha-1-antitrypsin in the tumor cells indicated the histiocytic nature of the tumor. Five fetal and five adult thymus glands were studied for the presence and distribution of true histiocytic cells. Histiocytes w...

journal_title：American journal of clinical pathology

authors： Szporn AH,Dikman S,Jagirdar J

更新日期：1984-12-01 00:00:00

abstract：:Soft-agar culture of transitional cell carcinoma colonies from urine, bladder irrigation fluid, and transurethral resection solid tumor specimens demonstrate generally better growth of tumor cell colonies from urine than from irrigation fluid. Growth of tumor colonies from urine was adequate to evaluate presence of tu...

journal_title：American journal of clinical pathology

authors： Kirkels WJ,Pelgrim OE,Debruyne FM,Vooijs GP,Herman CJ

更新日期：1982-11-01 00:00:00

abstract：:Platelet aggregation studies are usually performed in either electrical impedance or optical systems and the release reaction assessed by quantitating adenosine triphosphate (ATP) from luminesence produced by the firefly luciferin-luciferase system. In evaluating the results of such studies, attention is paid to a var...

journal_title：American journal of clinical pathology

authors： Sweeney JD,Labuzetta JW,Fitzpatrick JE

更新日期：1988-05-01 00:00:00

abstract：:Worldwide, infection with hepatitis viruses remains a major clinical and public heath concern. The laboratory is an integral part of the diagnosis of these infections since many of the manifestations are nonspecific, and the various hepatitis viruses show overlapping symptomatology. In this article, we discuss the lab...

journal_title：American journal of clinical pathology

authors： Harris KR,Dighe AS

更新日期：2002-12-01 00:00:00

abstract：:Using Venn diagrams derived from set theory, a mathematic model is presented that allows triple-label immunophenotypic analysis of cells based upon double-label measurements. Practical applications of this method are illustrated and discussed. Using this model, triple-label data concerning Leu-8 and Leu-9 (CD7) antige...

journal_title：American journal of clinical pathology

authors： Wood GS

更新日期：1989-07-01 00:00:00

abstract：:Staphylococcus epidermidis is among the most common organisms isolated from blood cultures. Conversely, it is rarely a well-documented cause of natural-valve endocarditis. However, several authors have reported series of patients with the clinical picture of endocarditis and S. epidermidis bacteremia. Most of these ca...

journal_title：American journal of clinical pathology

authors： Littenberg B,Cooper B,Levitz R

更新日期：1987-03-01 00:00:00

abstract：:Two atypical human non-Hodgkin's lymphomas (NHLs) that exhibited unusual genotypic and in situ immunophenotypic abnormalities are described. Immunophenotypically, both NHLs lacked surface Ig heavy chains. With the exception of the MB2 B-cell-associated antigen, no B- and T-cell differentiation antigen was detected in ...

journal_title：American journal of clinical pathology

authors： De Re V,Carbone A,Dolcetti R,Tirelli U,Folegotto C,Boiocchi M

更新日期：1990-10-01 00:00:00

abstract：:The professional activities of anatomic and clinical pathologists involve, to a large extent, management issues. To evaluate the management training received by pathology residents, the authors surveyed pathology residency training programs in the United States. Responses were collected from 138 of 187 programs (73.8%...

journal_title：American journal of clinical pathology

authors： Brugnara C,Fenton T,Winkelman JW

更新日期：1994-05-01 00:00:00

abstract：:The cases of 20 patients, each of whom has a positive lupus erythematosus cell preparation and a negative antinuclear factor test, are presented. The concept of a false-positive lupus erythematosus preparation is suggested. Five common mechanisms causing a false-negative antinuclear factor test are discussed and evalu...

journal_title：American journal of clinical pathology

authors： Koller SR,Johnston CL Jr,Moncure CW

更新日期：1976-09-01 00:00:00

abstract：:Fresh open lung biopsy material from 57 patients was incubated with fluoresceinated complement and immunoglobulin antisera. An indirect immunofluorescent assay using neonatal lung as substrate was conducted as well. Direct immunofluorescent patterns could be categorized into interalveolar septal capillary deposition, ...

journal_title：American journal of clinical pathology

authors： Magro CM,Morrison C,Pope-Harman A,Rothrauff SK,Ross P Jr

更新日期：2003-02-01 00:00:00

abstract：:Possible increased activation of the coagulation pathway was measured in a group of patients with neoplastic diseases. In addition to standard tests, the thromboplastin generation test, thrombin generation test and immunologic and coagulant activities of both Factor VIII and antithrombin III were utilized in the evalu...

journal_title：American journal of clinical pathology

authors： Losito R,Beaudry P,Valderrama JC,Cousineau L,Longpré B

更新日期：1977-08-01 00:00:00

abstract：:The evaluation of quality control (QC) practices from the College of American Pathologists (CAP) Microbiology Surveys demonstrates a trend away from daily controls similar to that first noted in 1980. Previous recommendations for more relevant cost-containment oriented weekly QC procedures are discussed, and the 1982 ...

journal_title：American journal of clinical pathology

authors： Jones RN,Edson DC,Gilmore BF

更新日期：1983-10-01 00:00:00

abstract：:Uterine tumors with histologic resemblances to ovarian sex-cord tumors were encountered in 14 women in the fourth to sixth decades of life, most of whom had abnormal vaginal bleeding and enlarged uteri suggesting leiomyomas. The tumors in six cases (Group I) were identical to one or another form of well-recognized end...

journal_title：American journal of clinical pathology

authors： Clement PB,Scully RE

更新日期：1976-09-01 00:00:00

abstract：:A critical limit protocol requiring that all point of care glucose meter readings > 22.2 mmol/L (400 mg/dL) and < 2.2 mmol/L (40 mg/dL) be immediately confirmed by the laboratory was assessed. A total of 193 (2%) of 9,523 glucose meter determinations (63 patients) were > 22.2 or < 2.2 mmol/L. One hundred twenty-two (6...

journal_title：American journal of clinical pathology

authors： Lum G

更新日期：1996-09-01 00:00:00

abstract：:The cytodiagnosis of Pneumocystis carinii (PC) in bronchoalveolar lavage (BAL) fluids has traditionally required a special stain such as Gomori's methenamine silver (GMS) stain. Recent reports indicate that identification of foamy alveolar casts (FACs) with Papanicolaou's (Pap) stain may provide a sensitive and less c...

journal_title：American journal of clinical pathology

authors： Schumann GB,Swensen JJ

更新日期：1991-04-01 00:00:00

abstract：:Fifteen cases of low-grade B-cell lymphoma involving unusual extranodal sites have been studied in comparison to cases reported or observed arising in typical mucosa-associated lymphoid tissues. In every case, histopathologic features conformed to those characteristic for lymphomas of mucosa-associated lymphoid tissue...

journal_title：American journal of clinical pathology

authors： Pelstring RJ,Essell JH,Kurtin PJ,Cohen AR,Banks PM

更新日期：1991-12-01 00:00:00

abstract：:Proliferative lesions, which include collagen, elastic fibers and abnormally oriented muscle fibers, were found to develop in intramyocardial arteries more rapidly with age in cigarette smokers than in nonsmokers. The study attempted to determine whether these lesions reduce perfusion pressures in the subendocardial z...

journal_title：American journal of clinical pathology

authors： Naeye RL,Truong LD

更新日期：1977-10-01 00:00:00