Meningorectal fistula as a cause of polymicrobial anaerobic meningitis.

Abstract:

:A 49-year-old diabetic woman developed polymicrobial anaerobic meningitis secondary to a meningorectal fistula one year after receiving neutron beam therapy for a rectal adenocarcinoma. The meningitis was refractory to chloramphenicol and penicillin but responded to oral metronidazole. Sustained eradication of meningitis was achieved with continued metronidazole for 51/2 months, despite persistence of the fistula. Metronidazole may be a superior antimicrobial agent for polymicrobial anaerobic meningitis, especially when caused by a large or continuing bacterial inoculum. This meningorectal fistula is the first of its kind to our knowledge to be demonstrated by microbiologic, radiologic, and pathologic studies.

journal_name

Am J Clin Pathol

authors

Walsh TJ,Weinstein RA,Malinoff H,Breyer MD,Berelowitz BA

doi

10.1093/ajcp/78.1.127

subject

Has Abstract

pub_date

1982-07-01 00:00:00

pages

127-30

issue

1

eissn

0002-9173

issn

1943-7722

journal_volume

78

pub_type

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