Abstract:
Objectives:To determine non-American Society for Clinical Pathology pathology- and laboratory-related Choosing Wisely recommendations that drive effective test utilization in the laboratory. Methods:Data were collected via a two-part web-based survey distributed to a broad sample of pathologists and laboratory professionals from a variety of institutions. Results:Pathologists' most relevant recommendation: "Do not transfuse more units of blood than absolutely necessary"; highest priority: "Do not transfuse more than the minimum number of RBC units necessary to relieve symptoms of anemia or to return a patient to a safe hemoglobin range (7-8 g/dL in stable, noncardiac inpatients)." Laboratory professionals' most relevant recommendation: "Avoid testing for a Clostridium difficile infection in the absence of diarrhea"; highest priority: "Do not routinely transfuse stable, asymptomatic hospitalized patients with a hemoglobin level greater than 7 to 8 g/dL." Conclusions:Most of the highest priority, most relevant recommendations among those surveyed concerned utilization of blood products and transfusion management.
journal_name
Am J Clin Patholjournal_title
American journal of clinical pathologyauthors
Waibel E,Garcia E,Kelly M,Soles R,Hilborne Ldoi
10.1093/ajcp/aqx159subject
Has Abstractpub_date
2018-02-17 00:00:00pages
267-274issue
3eissn
0002-9173issn
1943-7722pii
4841631journal_volume
149pub_type
杂志文章,评审abstract::We studied the histologic and multiparameter flow cytometry (MFC) features of 12 cases of angioimmunoblastic T-cell lymphoma (AITL), 13 of mature T-cell lymphoma, and 25 control cases of reactive lymphoid hyperplasia to evaluate the role of CD10 in the differential diagnosis of peripheral T-cell lymphomas (PTCLs). A c...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/MC7QRGPTV0LRR98X
更新日期:2007-11-01 00:00:00
abstract::In 42 patients with locally advanced breast cancer treated with neoadjuvant chemotherapy followed by surgery and radiation therapy, the effects of chemotherapy on tumor architecture, morphometric nuclear and nucleolar characteristics, DNA ploidy, proliferation index measured by mitotic activity index, expression of di...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/107.2.211
更新日期:1997-02-01 00:00:00
abstract::Pancreatic adenocarcinoma is believed to develop from histologically identifiable intraductal lesions known as pancreatic intraepithelial neoplasias (PanINs) that undergo a series of architectural, cytologic, and genetic changes, a progression model similar to the adenoma-carcinoma sequence in the colon. The apomucin ...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/7Y7N-M1WM-R0YK-M2VA
更新日期:2002-05-01 00:00:00
abstract:OBJECTIVES:Human epidermal growth factor receptor 2 (HER2, ERBB2) testing is an important prognostic/predictive marker in breast cancer management, especially in selecting HER2-targeted treatment. American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP) guidelines address HER2 status and were...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/AJCP3Q9WFOQTKUVV
更新日期:2015-08-01 00:00:00
abstract::To assess their applied clinical utility, viral cultures and serological tests for cytomegalovirus (CMV) were reviewed at Duke University Medical Center (DUMC), a 1,125-bed tertiary-care hospital. Less than 1% (3 of 1,216) of CMV cultures were positive, and 8% of serum samples (45 of 587) were positive by single sera ...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/106.2.180
更新日期:1996-08-01 00:00:00
abstract::A two-sample plot is often used to display test results in clinical chemistry external quality control programs. The use of control materials at different concentrations calls for a re-evaluation of the two-sample plot. A modification of the two-sample plot is presented. The axes of the graph are graduated in units of...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/67.1.91
更新日期:1977-01-01 00:00:00
abstract::Measuring HER-2 is important for selecting optimal therapy and predicting prognosis in breast cancer patients. Current methods for evaluating HER-2 include measuring protein overexpression by immunohistochemistry (IHC), measuring gene copy number by fluorescent in situ hybridization (FISH), and measuring shed antigen ...
journal_title:American journal of clinical pathology
pub_type: 杂志文章,评审
doi:10.1309/D76M-QEGU-62BT-HKER
更新日期:2002-06-01 00:00:00
abstract::A structure resembling a sulfur granule found in histologic sections of endometrium from patients with intrauterine contraceptive devices is described. It is distinguished from a true sulfur granule on morphologic grounds and is further characterized as a foreign substance, most probably fragments of the synthetic con...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/75.6.822
更新日期:1981-06-01 00:00:00
abstract::Several adulterants are used to mask tests for abused drugs in urine. Adulterants such as "Klear" and "Whizzies" contain potassium nitrite, and "Urine Luck" contains pyridinium chlorochromate (PCC). The presence of these adulterants cannot be detected by routine specimen integrity checks (pH, specific gravity, and tem...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/9Q2G-6CTH-XT16-HCCC
更新日期:2002-02-01 00:00:00
abstract::Few cases of secondary CD5+ diffuse large B-cell lymphoma (DLBCL) that are not Richter syndrome have been reported previously. We report 9 cases of non-Richter syndrome secondary CD5+ DLBCL. Among 529 cases of DLBCL, 38 (7.2%) were CD5+ DLBCL, including 9 of secondary CD5+ DLBCL. Five cases gained CD5 expression durin...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/AJCP58FETFGLCKKW
更新日期:2009-03-01 00:00:00
abstract::Mantle cell lymphoma (MCL) is characterized by typical morphologic features and the CD5+, CD23-immunophenotype. However, some morphologically typical MCLs are CD23+. A t(11;14)(q13;q32) translocation is frequently found in MCL, leading to overexpression of cyclin D1. We studied the expression of cyclin D1 in 50 small ...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/R2BC-2H7T-7KB6-0YG8
更新日期:2002-02-01 00:00:00
abstract::Borrelia burgdorferi is difficult to detect in routine biopsy material from patients with skin lesions of borreliosis. In this study, a new immunohistochemical method, focus floating microscopy (FFM), was developed to detect B burgdorferi in tissue sections and was compared with polymerase chain reaction (PCR). By usi...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/3369XXFPEQUNEP5C
更新日期:2007-02-01 00:00:00
abstract::The authors report two cases of vernix caseosa peritonitis, an infrequent complication of cesarean section with distinctive histopathologic findings. Both patients underwent exploratory laparotomy for unexplained abdominal pain after cesarean section. Histopathologic evaluation of surgically removed tissue revealed an...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/103.6.681
更新日期:1995-06-01 00:00:00
abstract:OBJECTIVES:To determine the public health surveillance severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing volume needed, both for acute infection and seroprevalence. METHODS:Required testing volumes were developed using standard statistical methods based on test analytical performance, disease preval...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/aqaa099
更新日期:2020-07-07 00:00:00
abstract::We evaluated the performance (ie, imprecision, inaccuracy, and analytic sensitivity) of the Sysmex SE-9000 commercial hematology analyzer (TOA Medical Electronics, Kobe, Japan) on differential leukocyte counts according to the National Committee for Clinical Laboratory Standards H20-A protocol. The results obtained we...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/108.6.674
更新日期:1997-12-01 00:00:00
abstract::Reported is a case of a rare lymphoepithelial cyst of the tail of the pancreas that developed in a young man with no symptoms. To the authors' knowledge, it is the first case described to be entirely situated within the pancreas, thus confirming its pancreatic origin. Biologic behavior appears to be entirely benign, a...
journal_title:American journal of clinical pathology
pub_type: 杂志文章,评审
doi:10.1093/ajcp/98.2.188
更新日期:1992-08-01 00:00:00
abstract::The standard method for detecting antinuclear antibodies (ANAs) is by immunofluorescence assay (IFA), a method that is labor intensive and subjective. In an attempt to overcome these limitations, several commercial enzyme immunoassays (EIAs) have been developed. We report the results of our evaluation of the ANA Micro...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/111.4.503
更新日期:1999-04-01 00:00:00
abstract::Thirty-five consecutive renal biopsy specimens were evaluated by light histology using paraffin and glycol methacrylate embedding. The clarity of the renal structures was found to be much better, and the renal lesions better defined, using glycol methyacrylate embedding. ...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/64.5.655
更新日期:1975-11-01 00:00:00
abstract::The Sysmex R-3000 (TOA Medical Electronics, Kobe, Japan) evaluates maturation of reticulocytes by quantitating the fraction of reticulocytes within low-, middle-, and high-fluorescence intensity regions. We defined the immature reticulocyte fraction (IRF) as the sum of the fraction of high-fluorescence intensity regio...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVES:Cytogenetics defines disease entities and predicts prognosis in acute myeloid leukemia (AML). Conventional karyotyping provides a comprehensive view of the genome, while fluorescence in situ hybridization (FISH) detects targeted abnormalities. The aim of this study was to compare the utility of karyotyping a...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/AJCPP6LVMQG4LNCK
更新日期:2015-06-01 00:00:00
abstract::We analyzed the value in cervical cytology of a recently developed technique by which it is possible to remove thick tissue specimens, called microbiopsies, from cervical smears and to process them for histologic examination. In 12 (48%) of 25 cervical smears in which microbiopsies were found, the histologic sections ...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/108.2.191
更新日期:1997-08-01 00:00:00
abstract::We determined whether there were additional diagnostic findings in additional level sections performed on polyps with no pathologic diagnosis (NPD) or those in which only lymphoid aggregates (LAs) were seen initially and determined the level at which findings were identified. All colorectal biopsy specimens submitted ...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/27NQ-A1R2-DQ41-20Y7
更新日期:2002-03-01 00:00:00
abstract:OBJECTIVES:To demonstrate the impact of genetics specialists on identifying test order errors and improving reimbursement for genetic testing. METHODS:Forty-four cases in which whole exome sequencing (WES) was performed but not reimbursed were reviewed by a genetic counselor through simulated prospective and retrospec...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/aqz188
更新日期:2020-03-09 00:00:00
abstract::Primary massive ovarian edema is uncommon, particularly when it involves both ovaries before puberty. Ovarian edema secondary to a preexisting ovarian lesion is one of the postulated mechanisms. A prepubertal girl presented with bilateral massive ovarian edema with stromal hyperthecosis, which may have predisposed bot...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/91.5.597
更新日期:1989-05-01 00:00:00
abstract::Two hundred forty-three patients who had pathologically verified primary osteosarcomas of bone, treated at The University of Texas System Cancer Center, M. D. Anderson Hospital and Tumor Institute over a 24-year period, form the basis of this study. These cases provide a basis for comparison of those patients currentl...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/67.5.427
更新日期:1977-05-01 00:00:00
abstract::An automated calcium method based on o-cresolphthalein complexone chemistry and designed to be used in conjunction with the Beckman ASTRA systems (Beckman Instruments, Inc., Brea, CA) was evaluated. Day-to-day reproducibility studies yielded coefficients of variation ranging from 1.2 to 3.1%. Linearity was 5.0-15.5 mg...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/82.2.182
更新日期:1984-08-01 00:00:00
abstract::Histologic follow-up of patients with the Bethesda system cervical-vaginal diagnosis of atypical glandular cells of undetermined significance (AGUS), "favor endocervical origin", or "not otherwise specified" (NOS) shows a high percentage of clinically significant (neoplastic or preneoplastic) lesions. Using the criter...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/107.3.299
更新日期:1997-03-01 00:00:00
abstract::A study was made of quantitative urine cultures in bacteremic patients with urinary tract infection as the only identifiable source. These patients represent the most serious form of urinary tract infection and should be recognized as significant by the criteria used for interpreting quantitative urine cultures. In 83...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/85.5.616
更新日期:1986-05-01 00:00:00
abstract::Proteomic studies of cells via surface-enhanced laser desorption/ionization spectrometry (SELDI) analysis have enabled rapid, reproducible protein profiling directly from crude samples. We applied this technique to archival cytology material to determine whether distinct, reproducible protein fingerprints could be ide...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/EJKL-7328-KFPR-56WA
更新日期:2002-12-01 00:00:00
abstract::Adenomatous polyps are common neoplastic lesions of the large intestine. The risk of carcinoma increases with polyp size. Small polyps are typically totally embedded for histologic examination, but no standard method for sampling large, grossly benign polyps has been established. We reviewed grossly noninvasive adenom...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/804U-LHU1-TJ00-UGAU
更新日期:2001-09-01 00:00:00