The usefulness of flow cytometric CD10 detection in the differential diagnosis of peripheral T-cell lymphomas.

abstract：:A series of 138 patients seen consecutively in an adult allergy clinic were studied to determine serum alpha1-antitrypsin (alpha1-AT) levels and protease inhibitor (Pi) phenotypes. These were compared with a control group of 700 healthy young adult blood donors. Both total serum trypsin inhibitory capacity (STIC) and ...

journal_title：American journal of clinical pathology

authors： Ihrig J,Schwartz HJ,Rynbrandt DJ,Kleinerman J

更新日期：1975-09-01 00:00:00

abstract：:A patient with a polymicrobial bacteremia due to Nocardia asteroides and Escherichia coli is presented. Rapid overgrowth of all cultures with the E. coli necessitated the use of selective media containing antimicrobial agents to which the E. coli was sensitive. Only five previous cases of N. asteroides bacteremia have...

journal_title：American journal of clinical pathology

authors： Ruebush TK 2nd,Goodman JS

更新日期：1975-10-01 00:00:00

abstract：:Coronary artery disease (CAD) is the leading cause of death in the United States. Increasing evidence suggests involvement of inflammation in the atherosclerotic process. We examined cytokines and other inflammatory markers in 865 patients with chest pain in whom coronary angiography revealed no evidence of CAD or CAD...

journal_title：American journal of clinical pathology

authors： Martins TB,Anderson JL,Muhlestein JB,Horne BD,Carlquist JF,Roberts WL,Carlquist JF

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVES:The coronavirus disease 2019 pandemic has halted in-person medical student education in many large academic centers, including the University of Washington. We identified a unique opportunity to bring comprehensive and targeted anatomic pathology training to large numbers of medical students who would not re...

journal_title：American journal of clinical pathology

authors： Parker EU,Chang O,Koch L

更新日期：2020-10-13 00:00:00

abstract：:Mechanical release of single cell suspensions from solid tumors for DNA analysis by flow cytometry has been shown to be optimal for adenocarcinomas in general. In the breast, many adenocarcinomas are fibrotic or scirrhous, creating difficulty in separating the neoplastic cells from the stroma. The authors have conduct...

journal_title：American journal of clinical pathology

authors： Torres FX,Mackowiak PG,Brown RD,Linden MD,Zarbo RJ

更新日期：1995-01-01 00:00:00

abstract：:Protease inhibitor serpin-B2 (plasminogen activator inhibitor-2 [PAI-2]) protects pRb from degradation in human papillomavirus (HPV)-18+ HeLa cells. Our objective was to assess whether the pRb-mediated HPV-suppressive effect of PAI-2 in cancer cell lines has implications in the outcome of HPV infections. Cervical biop...

journal_title：American journal of clinical pathology

authors： Syrjänen S,Naud P,Sarian L,Derchain S,Roteli-Martins C,Longatto-Filho A,Tatti S,Branca M,Erzen M,Hammes LS,Costa S,Syrjänen K

更新日期：2009-12-01 00:00:00

abstract：:Immunophenotypic analysis of acute leukemias is time consuming and often requires flow cytometric analysis. A 1-hour alkaline phosphatase-labeled streptavidin-biotin immunocytochemical procedure was evaluated as an alternative. Seventeen cases of acute leukemia, including 10 acute lymphocytic (ALL) and 7 acute nonlymp...

journal_title：American journal of clinical pathology

authors： Hammer RD,Collins RD,Ebrahimi S,Casey TT

更新日期：1992-06-01 00:00:00

abstract：:Fatty acid synthase is an enzyme that catalyzes the synthesis of long-chain fatty acids. The enzyme expression is minimal in adult tissues and very high in many cancers. Ulcerative colitis is a chronic inflammatory bowel disease that, when long-standing, is associated with an increased risk of colon cancer. The aim of...

journal_title：American journal of clinical pathology

authors： Consolazio A,Alò PL,Rivera M,Iacopini F,Paoluzi OA,Crispino P,Pica R,Paoluzi P

更新日期：2006-07-01 00:00:00

abstract：:To study the usefulness of calretinin as an immunohistochemistry marker in the diagnosis of cardiac myxoma (CM) and the origin of myxoma cells, we examined 24 CMs and 9 fetal hearts with immunohistochemical methods on formalin-fixed paraffin-embedded tissues. We compared 24 CMs with 10 mural thrombi, 6 jaw myxomas, an...

journal_title：American journal of clinical pathology

authors： Terracciano LM,Mhawech P,Suess K,D'Armiento M,Lehmann FS,Jundt G,Moch H,Sauter G,Mihatsch MJ

更新日期：2000-11-01 00:00:00

abstract：:A case of a patient with otherwise typical multiple myeloma whose myeloma cells were phagocytic is described. Phagocytosis of erythrocytes, erythrocytic precursors, lymphocytes, and platelets was found. Ingestion of latex particles by myeloma cells was demonstrated in vitro. ...

journal_title：American journal of clinical pathology

authors： Fitchen JH,Lee S

更新日期：1979-06-01 00:00:00

abstract：:Although the hematopoietic origin of mast cells is very probable, the cell from which they originate is still a matter of speculation. The description of "transitional basophil/mast cells" in myeloproliferative disorders has suggested a common origin for basophils and mast cells. In a case of mast cell transformation ...

journal_title：American journal of clinical pathology

authors： Gabriel LC,Escribano LM,Marie JP,Zittoun R,Navarro JL

更新日期：1986-08-01 00:00:00

abstract：:The aim of this study was to evaluate the histopathologic features and the expression of angiogenesis-related markers in primary tumors and metastatic lymph nodes of oral squamous cell carcinomas (SCCs) with multiple lymph node involvement in comparison with oral SCCs without nodal metastasis. The protein levels of th...

journal_title：American journal of clinical pathology

authors： Nikitakis NG,Rivera H,Lopes MA,Siavash H,Reynolds MA,Ord RA,Sauk JJ

更新日期：2003-04-01 00:00:00

abstract：:In five patients with eosinophilia and myeloproliferative disorders, the IgE levels were normal, and immune complexes were not detected. In contrast, in six patients with reactive eosinophilia accompanying immunologic diseases, the IgE levels were elevated in five, and immune complexes were elevated in two. Five of si...

journal_title：American journal of clinical pathology

authors： Crowley JP,Myers TJ

更新日期：1983-03-01 00:00:00

abstract：:An immunohistochemical study was conducted of 108 papillary carcinoma cases, including 48 cases with intratumoral heterotopic ossification (IHO). In 48 cases, papillary carcinoma with IHO was accompanied by nodular fibrosis. Cases of papillary carcinoma with IHO or nodular fibrosis showed higher incidences of lymph no...

journal_title：American journal of clinical pathology

authors： Takeda M,Mikami T,Numata Y,Okamoto M,Okayasu I

更新日期：2013-05-01 00:00:00

abstract：:A case of metastatic ameloblastoma of the maxilla with secondary hypercalcemia in a 54-year-old man is presented. After treatment with surgery, chemotherapy, and radiotherapy, the patient was found to have multiple metastases and severe hypercalcemia associated with high levels of parathormone-like substance in the pe...

journal_title：American journal of clinical pathology

authors： Madiedo G,Choi H,Kleinman JG

更新日期：1981-04-01 00:00:00

abstract：:A 3-year-old girl of Navajo heritage had intractable diarrhea beginning at 4 days of age and resulting in long-term hyperalimentation. Investigation before multivisceral transplantation included biopsies of the rectum, stomach, duodenum, and liver. The diagnosis of microvillus inclusion disease was established by docu...

journal_title：American journal of clinical pathology

authors： Schofield DE,Agostini RM Jr,Yunis EJ

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVES:Nucleic acid amplification tests on formalin-fixed, paraffin-embedded (FFPE) tissue specimens enable Mycobacterium tuberculosis complex (MTB) detection and rapid tuberculosis diagnosis in the absence of microbiologic culture tests. We aimed to evaluate the efficacy of different polymerase chain reaction (PCR...

journal_title：American journal of clinical pathology

authors： Seo AN,Park HJ,Lee HS,Park JO,Chang HE,Nam KH,Choe G,Park KU

更新日期：2014-09-01 00:00:00

abstract：:Twenty-eight resected primary non-small cell lung carcinomas were studied for intratumoral DNA variability by flow cytometry (FCM). Three separate tissue specimens from each resected tumor were divided equally for FCM analysis and histologic evaluation. FCM analysis also was performed on fine-needle aspirates (FNAs) f...

journal_title：American journal of clinical pathology

authors： Sara A,el-Naggar AK

更新日期：1991-09-01 00:00:00

abstract：:Trends in surgical practice suggest that pathologists will encounter increased numbers of patients with small invasive ductal adenocarcinomas; small, if any, metastatic deposits in axillary lymph nodes (ALNs); and possibly fewer ALN specimens to examine. New prognostic histologic features may be needed in this environ...

journal_title：American journal of clinical pathology

authors： Goldstein NS,Mani A,Vicini F,Ingold J

更新日期：1999-01-01 00:00:00

abstract：:Three cases of pulmonary squamous cell carcinoma (SCC) are described displaying a prominent microcystic pattern closely resembling microcystic adnexal carcinoma of the skin (MAC). The patients were 2 women and 1 man aged 72 to 83 years. Histologically, in addition to conventional SCC, all tumors showed striking microc...

journal_title：American journal of clinical pathology

authors： Weissferdt A,Moran CA

更新日期：2011-09-01 00:00:00

abstract：:The most common differentiated renal tumor of early childhood is the congenital mesoblastic neophroma. Well-differentiated forms of Wilms' tumor may present a difficult differential diagnosis from these benign neoplasms. The cases of two patients found to have well-differentiated renal neoplasms after being treated fo...

journal_title：American journal of clinical pathology

authors： Hughson MD,Hennigar GR,Othersen HB Jr

更新日期：1976-08-01 00:00:00

abstract：:Patients with chronic renal failure (CRF) are at increased risk for myocardial events that are difficult to evaluate due to atypical symptoms and chronically elevated protein markers of cardiac damage. This study evaluated cardiac troponin T (cTnT), a sensitive marker of cardiac injury, in patients with CRF without my...

journal_title：American journal of clinical pathology

authors： Frankel WL,Herold DA,Ziegler TW,Fitzgerald RL

更新日期：1996-07-01 00:00:00

abstract：Objectives:To analyze the economic impact of testing for activated protein C resistance (APC-R) due to factor V Leiden (FVL) mutation with APC-R with reflexive FVL genotyping (algorithmic approach) or genotyping alone. Methods:OptumLabs Data Warehouse (OLDW) data were used to assess testing approaches. Insurance claim...

journal_title：American journal of clinical pathology

authors： Perez Botero J,Majerus JA,Strege AK,Johnson RD,Chen D,Pruthi RK

更新日期：2017-06-01 00:00:00

abstract：:The availability of automated anti-Xa heparin assays provides the opportunity to manage patient unfractionated heparin levels directly, rather than by the activated partial thromboplastin time. Because critically ill patients can acquire an antithrombin deficiency, we compared the performance of 3 anti-Xa heparin assa...

journal_title：American journal of clinical pathology

authors： Lehman CM,Rettmann JA,Wilson LW,Markewitz BA

更新日期：2006-09-01 00:00:00

abstract：:This report describes the selective staining of lysosomes in cells of neutrophilic granulocytic origin by the azo textile dye basic blue 93. Used as a single agent aqueous stain after fixation, the dye stained lysosomes black. Stained in this way, lysosomes were sharply delimited and easily visualized. Large numbers o...

journal_title：American journal of clinical pathology

authors： Kass L

更新日期：1988-02-01 00:00:00

abstract：:The development and general concepts of the Système International d'Unités (SI units) are discussed. The basic and derived quantities and units of the SI used for clinical laboratory data are reviewed. Ranges of normal values for a number of body fluid constituents are given in the units in current general use and in ...

journal_title：American journal of clinical pathology

authors： Lehmann HP

更新日期：1976-01-01 00:00:00

abstract：:We report 8 cases of hepatosplenic T-cell lymphoma (HSTCL) involving bone marrow and correlate histologic findings with disease progression. Immunophenotypic analysis demonstrated mature, aberrant gamma/delta T-cell immunophenotypes. Isochromosome 7q was identified in 4 cases; 1 case showed the t(7;14)(q34;q13). Seven...

journal_title：American journal of clinical pathology

authors： Vega F,Medeiros LJ,Bueso-Ramos C,Jones D,Lai R,Luthra R,Abruzzo LV

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVES:Certain laboratory tests are critical for patient care and must be communicated rapidly. Professional societies have developed guidelines for reporting of "critical values" and significant or unexpected surgical pathology findings. Urgent diagnoses requiring rapid reporting include new or unexpected diagnose...

journal_title：American journal of clinical pathology

authors： Layfield LJ,Schnabel JL

更新日期：2014-12-01 00:00:00

abstract：:In the differential diagnosis of Spitz nevus vs malignant melanoma, patient age provides a critical piece of clinical information, because Spitz nevi occur mostly in children and melanomas occur mostly in adults. Nevertheless, there is overlap in the age distributions of Spitz nevus and melanoma. The issue to consider...

journal_title：American journal of clinical pathology

authors： Vollmer RT

更新日期：2004-06-01 00:00:00

abstract：:Lymphocyte populations with abnormal kappa/lambda ratios have been described previously in B-cell non-Hodgkin's lymphomas and in lymphoid hyperplasia. The authors studied 12 patients in whom lymph nodes diagnostic of Hodgkin's disease contained evidence of monoclonal lymphocyte proliferation. One patient subsequently ...

journal_title：American journal of clinical pathology

authors： Bain GO,Bain VG

更新日期：1984-12-01 00:00:00