Comparison of an enzyme immunoassay to an indirect fluorescent immunoassay for the detection of antinuclear antibodies.

abstract：:For quality-control purposes, federal regulations require cytology laboratories to compare Papanicolaou smear and cervical biopsy reports, if available, and determine the cause of any discrepancies. The authors reviewed 56,497 cervicovaginal smears, of which 1,582 (2.8%) had a subsequent cervical biopsy or endocervica...

journal_title：American journal of clinical pathology

authors： Joste NE,Crum CP,Cibas ES

更新日期：1995-01-01 00:00:00

abstract：:This study assessed the value of argyrophilic nucleolar organizer region (AgNOR) staining as a potential technique for the estimation of cell kinetics in conventional histology sections, in benign and malignant breast lesions. Using a silver staining technique and immunohistochemistry, the authors correlated the numbe...

journal_title：American journal of clinical pathology

authors： Dervan PA,Gilmartin LG,Loftus BM,Carney DN

更新日期：1989-10-01 00:00:00

abstract：:This review summarizes our experience using blinded review as a method to measure quality in surgical pathology. It details the specifics about how the review is performed, the weaknesses in the method, and then summarizes our results so far. These results suggest that error rates correlate with the individual patholo...

journal_title：American journal of clinical pathology

authors： Renshaw AA,Gould EW

更新日期：2007-01-01 00:00:00

abstract：:We describe the development and testing of a novel pre-sign-out quality assurance tool for case diagnoses that allows for the random review of a percentage of cases by a second pathologist before case verification and release of the final report. The tool incorporates the ability to record and report levels of diagnos...

journal_title：American journal of clinical pathology

authors： Owens SR,Dhir R,Yousem SA,Kelly SM,Piccoli A,Wiehagen L,Lassige K,Parwani AV

更新日期：2010-06-01 00:00:00

abstract：:In a preliminary attempt to distinguish random intrinsic and methodologic variations of blood lipid levels from any that have possibly been induced by ingestion of vitamin E, blood samples were analyzed in duplicate for lipids several times before and during oral vitamin E administration. Three of eight subjects showe...

journal_title：American journal of clinical pathology

authors： Muckle TJ,Nazir DJ

更新日期：1989-02-01 00:00:00

abstract：:This article deals with and formalizes 2 notions common to the practice of pathology. The first is that the number of lymph nodes found positive for metastasis relates directly to the total number of lymph nodes examined. The second is that for any patient, there is a chance that the absence of lymph node metastases i...

journal_title：American journal of clinical pathology

authors： Vollmer RT

更新日期：2005-05-01 00:00:00

abstract：:Mucocele-like tumors of the breast originally were reported by Rosen in 1986 as benign lesions that histologically resembled colloid carcinoma of the breast. The authors document two cases of mucocele-like tumors to illustrate the difficulty in separating these lesions from colloid carcinoma on the basis of fine-needl...

journal_title：American journal of clinical pathology

authors： Bhargava V,Miller TR,Cohen MB

更新日期：1991-06-01 00:00:00

abstract：:Quantitative morphometry was used to evaluate the homogeneity of lymphoid cell populations in fine-needle aspiration cytology smears of lymph nodes from eight non-Hodgkin's lymphomas and four benign lymphoid proliferations. Using the standard deviation of log-transformed nuclear areas as the measure of lymphoid cell h...

journal_title：American journal of clinical pathology

authors： Dawsey SM,Korn EL,Layfield LJ

更新日期：1989-10-01 00:00:00

abstract：:Hairy cell populations of greater than 90 purity were prepared from six samples obtained from four patients with leukemic reticuloendotheliosis (LRE). These then were analyzed for surface immunoglobulin (SIg) and antigens specified by a panel of monoclonal antibodies. The hairy cells from all patients displayed SIg an...

journal_title：American journal of clinical pathology

authors： Janckila AJ,Stelzer GT,Wallace JH,Yam LT

更新日期：1983-04-01 00:00:00

abstract：:The thickness of eosinophilic band in collagenous colitis (CC) was assessed by 3 methods: histologic estimates (22 observers), conventional measurements using a calibrated micrometric scale (1 observer), and semiautomatic micrometric measurements (1 observer). By the histologic estimate technique, 7.4% of the results ...

journal_title：American journal of clinical pathology

authors： Rubio CA,Orrego A,Höög A,Porwitz A,Petersson F,Elmberger G,Glaessgen A,Eriksson E,Kanter L,Jaremko G,Egevad L,Laforga J,Liljefors M,Löfdahl B,Norman P,Larsson O,Wanat R,Wejde J,Zickert P,Björk J,Caini S,Palli D

更新日期：2008-09-01 00:00:00

abstract：:This study was undertaken to compare several methods of evaluating the common assumption that laboratory data may be treated as if they had been drawn from an underlying Gaussian distribution. As had been described earlier, the usual Kolmogorov-Smirnov test was found to be unsatisfactory due to its sensitivity to roun...

journal_title：American journal of clinical pathology

authors： Rossing RG,Hillis A,Chou DY

更新日期：1985-05-01 00:00:00

abstract：:We conducted this study to ascertain the prevalence of erb-b2 gene amplification in breast cancer specimens read as 2+ in immunohistochemical analysis. Slides from patients with metastatic or recurrent breast cancer were eligible for fluorescent in situ hybridization (FISH) study if they were read as 2+ immunohistoche...

journal_title：American journal of clinical pathology

authors： Lan C,Liu JM,Liu TW,Hsu DH,Liang S,Chen JR,Peng JW

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVES:To assess the ability of flow cytometry (FC) to detect putative neoplastic T-cell subsets on skin shave biopsy (SSB) specimens from patients with mycosis fungoides (MF) and to study the immunophenotype of skin-infiltrating tumor cells in MF. METHODS:SSB specimens from patients with suspected MF were bisecte...

journal_title：American journal of clinical pathology

authors： Horna P,Kurant D,Sokol L,Sotomayor EM,Moscinski L,Glass LF

更新日期：2015-06-01 00:00:00

abstract：:We compared prothrombin times (PTs) and international normalized ratios (INRs) for blood samples drawn into plastic vs glass collection tubes. We collected 60 venous blood samples into 4.5-mL glass and 2 plastic tubes (2.7 and 3.5 mL). An additional 153 samples, including 63 from warfarin-anticoagulated patients, were...

journal_title：American journal of clinical pathology

authors： Fiebig EW,Etzell JE,Ng VL

更新日期：2005-12-01 00:00:00

abstract：:Four acid hydrolases, acid phosphatase (AP), alpha-naphthyl acetate esterase (ANAE), beta-glucuronidase, and N-acetyl-beta-glucosaminidase, were determined cytochemically in peripheral blood lymphocytes from 50 patients with B and T chronic lymphocytic and prolymphocytic leukemias (CLL, PLL) and related disorders. Str...

journal_title：American journal of clinical pathology

authors： Crockard A,Chalmers D,Matutes E,Catovsky D

更新日期：1982-10-01 00:00:00

abstract：:Infusible platelet membranes (IPMs) prepared from fresh or outdated human platelets have been shown to correct prolonged bleeding times in thrombocytopenic rabbits. In previous trials, IPMs did not seem to be immunogenic and lacked dose-limiting toxicity. The present study was undertaken to explore whether the platele...

journal_title：American journal of clinical pathology

authors： Graham SS,Gonchoroff NJ,Miller JL

更新日期：2001-01-01 00:00:00

abstract：:A primary hepatic tumor with histologic features suggestive of carcinoid tumor is reported, and six previously reported cases reviewed. Tumor cells contained electron dense secretory granules with an average diameter 150-200 nm which demonstrated positive argyrophilic reactions. On immunohistochemistry, chromogranin A...

journal_title：American journal of clinical pathology

authors： Miura K,Shirasawa H

更新日期：1988-04-01 00:00:00

abstract：:An unusual case of acute myelomonocytic leukemia (AMML) in an 81-year-old man is described. Ultrastructural examination revealed the presence of distinct Auer bodies, which commonly are found in acute promyelocytic leukemia (APL). The Auer bodies had a splinterlike appearance with a distinct tubular substructure. The ...

journal_title：American journal of clinical pathology

authors： Payne CM,Harrow EJ

更新日期：1983-08-01 00:00:00

abstract：:Cytogenetic studies of bone marrow were performed in 230 consecutive cases of patients with chronic granulocytic leukemia (CGL) admitted to the National Cancer Institute since 1961. Twenty patients lacked the Philadelphia (Ph1) chromosome. All were previously untreated. When compared with Ph1-positive patients, CGL pa...

journal_title：American journal of clinical pathology

authors： Canellos GP,Whang-Peng J,DeVita VT

更新日期：1976-04-01 00:00:00

abstract：:Adenocarcinomas of the sigmoid colon and rectum were studied for the presence of blood group substances of the A, B, H system using the method of specific erythrocytic adherence. Of 17 adenocarcinomas studied, eight were found to have reactivity for blood group substances. All eight tumours showing reactivity for bloo...

journal_title：American journal of clinical pathology

authors： Cooper HS,Haesler WE Jr

更新日期：1978-06-01 00:00:00

abstract：:Proliferative activity in astrocytomas, measured by image cytometry, was related to prognosis. Fifty-eight astrocytic neoplasms (grade 1 or 2, 11; grade 3, 31; glioblastoma multiforme, 16) were immunostained for Ki-67 (MIB-1; 1:50) and proliferating cell nuclear antigen (PCNA; prediluted). Proliferative activity (nucl...

journal_title：American journal of clinical pathology

authors： Kirkegaard LJ,DeRose PB,Yao B,Cohen C

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVES:We evaluated efficacy of two dual immunohistochemistry (IHC) staining assays in assessing hairy cell leukemia (HCL) involvement in core biopsies and compared the results with concurrently collected flow cytometric data. METHODS:Overall, 148 patients with HCL (123 male, 25 female; mean age: 59.8 years; range...

journal_title：American journal of clinical pathology

authors： Gupta GK,Sun X,Yuan CM,Stetler-Stevenson M,Kreitman RJ,Maric I

更新日期：2020-02-08 00:00:00

abstract：:Progression of follicular lymphoma (FL) to a higher-grade lymphoma occurs in 25% to 60% of cases and frequently indicates a poor prognosis. The transformation is accompanied by alteration in morphologic features and clinical behaviors. Herein, we report a case of FL occurring in a 59-year-old woman with the developmen...

journal_title：American journal of clinical pathology

authors： Young KH,Xie Q,Zhou G,Eickhoff JC,Sanger WG,Aoun P,Chan WC

更新日期：2008-01-01 00:00:00

abstract：:To assess the observation that blood type B might be a marker for longevity, we reviewed the records and determined the ABO blood types of all patients who died in our hospital in 2004. Age was stratified by decade of death, and linear regressions were calculated by ABO percentage. ABO survival curves were compared. I...

journal_title：American journal of clinical pathology

authors： Brecher ME,Hay SN

更新日期：2011-01-01 00:00:00

abstract：:We describe 2 male patients in whom hepatosplenic gamma/delta T-cell lymphoma (HSTL) developed 6 and 10 years after renal transplantation. The onset was abrupt with systemic symptoms, cytopenia, and hepatosplenomegaly. The histologic examination of the spleen (case 1), liver, and bone marrow revealed sinusoidal infilt...

journal_title：American journal of clinical pathology

authors： Khan WA,Yu L,Eisenbrey AB,Crisan D,al Saadi A,Davis BH,Hankin RC,Mattson JC

更新日期：2001-07-01 00:00:00

abstract：:The defined antigen substrate sphere system is a simple method for detecting antigen or antibody in the circulation. The technic is based on the coupling of antigen or antibody with Sepharose 4B beads that have been activated by cyanogen bromide. In this study the activated beads were exposed to dengue antigen in the ...

journal_title：American journal of clinical pathology

authors： Boonpucknavig S,Bunnag C,Vuttiviroj O,Nimmannitya S

更新日期：1978-09-01 00:00:00

abstract：:The DNA of Borrelia burgdorferi spirochetes extracted by ammonium hydroxide was used as the template for nested polymerase chain reaction (PCR) amplification of the species-specific 16S ribosomal DNA (rDNA). The primers were those well known to be specific for signature sequence amplification of the B burgdorferi sens...

journal_title：American journal of clinical pathology

authors： Lee SH,Vigliotti VS,Vigliotti JS,Jones W,Pappu S

更新日期：2010-04-01 00:00:00

abstract：:Diffuse alveolar damage (DAD) is usually considered a generalized lung process. During five years the authors observed 83 patients with generalized DAD in 827 adult autopsies (10.1%) and 10 patients with identical, but localized, lesions. The authors propose the term regional alveolar damage (RAD) to designate localiz...

journal_title：American journal of clinical pathology

authors： Yazdy AM,Tomashefski JF Jr,Yagan R,Kleinerman J

更新日期：1989-07-01 00:00:00

abstract：:In 1985 Harvard Medical School initiated an experimental curriculum that incorporated many of the recommendations of the report on the General Professional Education of the Physician (GPEP). Key features are problem-based small group tutorials that emphasize active learning, with increased independent study time and a...

journal_title：American journal of clinical pathology

authors： Colvin RB,Wetzel MS

更新日期：1989-10-01 00:00:00

abstract：:Increasingly, all automated blood counts are not accompanied by a microscopic white blood cell differential. A popular strategy is to obtain a manual differential if any part of the automated blood count and differential is outside specified limits (the "diff-if" strategy). The authors compared two sets of criteria to...

journal_title：American journal of clinical pathology

authors： McClure S,Bates JE,Harrison R,Gilmer PR,Bessman JD

更新日期：1988-08-01 00:00:00