Image cytometric measurement of nuclear proliferation markers (MIB-1, PCNA) in astrocytomas. Prognostic significance.

abstract：:Two unusual cases of acute lymphoblastic leukemia-hand mirror variant (ALL-HMV) are presented. One patient demonstrated a mixed immunophenotype with HLA-DR, My7, transferrin receptor surface markers, and terminal deoxynucleotidyl transferase positivity. To the authors' knowledge, this is the first ALL-HMV reported wit...

journal_title：American journal of clinical pathology

authors： Schumacher HR,Desai SN,McClain KL,Domenico DR,Dizikes GJ,Bird ML

更新日期：1989-04-01 00:00:00

abstract：OBJECTIVES:Nucleic acid amplification tests on formalin-fixed, paraffin-embedded (FFPE) tissue specimens enable Mycobacterium tuberculosis complex (MTB) detection and rapid tuberculosis diagnosis in the absence of microbiologic culture tests. We aimed to evaluate the efficacy of different polymerase chain reaction (PCR...

journal_title：American journal of clinical pathology

authors： Seo AN,Park HJ,Lee HS,Park JO,Chang HE,Nam KH,Choe G,Park KU

更新日期：2014-09-01 00:00:00

abstract：:Mycobacterium leprae causes leprosy. M leprae strains collected worldwide have been genetically clonal, which poorly explains the varying severity and clinical features of the disease. We discovered a new Mycobacterium species from 2 patients who died of diffuse lepromatous leprosy (DLL). The Mycobacterium was purifie...

journal_title：American journal of clinical pathology

authors： Han XY,Seo YH,Sizer KC,Schoberle T,May GS,Spencer JS,Li W,Nair RG

更新日期：2008-12-01 00:00:00

abstract：:Workload recording as designed by the College of American Pathologists has proven to be an invaluable aid in the assessment of overall laboratory operation. The administrative information derived from the compilation of these workload statistics is utilized to provide effective and these workload statistics is utilize...

journal_title：American journal of clinical pathology

authors： Norbut AM,Foulis PR,Mendelow H

更新日期：1980-10-01 00:00:00

abstract：:Diffuse alveolar damage (DAD) is usually considered a generalized lung process. During five years the authors observed 83 patients with generalized DAD in 827 adult autopsies (10.1%) and 10 patients with identical, but localized, lesions. The authors propose the term regional alveolar damage (RAD) to designate localiz...

journal_title：American journal of clinical pathology

authors： Yazdy AM,Tomashefski JF Jr,Yagan R,Kleinerman J

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVES:We aimed to find descriptors to identify chronic lymphocytic leukemia (CLL), Sézary, granular, and villous lymphocytes among normal and abnormal lymphocytes in peripheral blood. METHODS:Image analysis was applied to 768 images from 15 different types of lymphoid cells and monocytes to determine four discrim...

journal_title：American journal of clinical pathology

authors： Puigví L,Merino A,Alférez S,Boldú L,Acevedo A,Rodellar J

更新日期：2019-06-05 00:00:00

abstract：:Urine myoglobin concentrations are measured clinically to assess rhabdomyolysis and the related risk of renal damage. We studied urine myoglobin concentrations in vitro to explore the factors affecting stability. Myoglobin was very unstable in urine specimens, especially below pH 6.5, and its immunoreactivity deterior...

journal_title：American journal of clinical pathology

authors： Chen-Levy Z,Wener MH,Toivola B,Daum P,Reyes M,Fine JS

更新日期：2005-03-01 00:00:00

abstract：:We surveyed 271 laboratories participating in a quality assessment program to ascertain whether the use of a calibration curve for determining the international normalized ratio (INR) would improve interlaboratory accuracy and precision. Lyophilized warfarinized samples with INR values assigned through manual calibrat...

journal_title：American journal of clinical pathology

authors： Brien WF,Baskerville JC,Taberner DA,Crawford L

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVES:Mantle cell lymphoma (MCL) may present de novo or undergo progression to a clinically aggressive variant, known as a blastoid or pleomorphic variant. We report an unusual case of classic MCL in a 78-year-old man with a typical immunophenotype, including CD5 positivity, who subsequently relapsed with CD5-nega...

journal_title：American journal of clinical pathology

authors： Miao Y,Lin P,Wang W,Jeffrey Medeiros L,Lu X

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:Our aim was to investigate the frequency of steatohepatitic morphology in hepatocellular adenoma (HCA) and correlate with its clinical parameters and risk factors underlying nonalcoholic fatty liver disease (NAFLD) or nonalcoholic steatohepatitis (NASH). METHODS:We examined a series of 41 liver resection sp...

journal_title：American journal of clinical pathology

authors： Liu Y,Zen Y,Yeh MM

更新日期：2020-09-08 00:00:00

abstract：OBJECTIVES:Bladder cancers invading the muscularis mucosae (MM) are treated differently from those invading the muscularis propria (MP). However, it may be difficult to determine the type of smooth muscle in transurethral resection (TUR) or biopsy specimens. We aimed to investigate the clinicopathologic features of bla...

journal_title：American journal of clinical pathology

authors： Hwang MJ,Kamat AM,Dinney CP,Czerniak B,Guo CC

更新日期：2020-07-07 00:00:00

abstract：:The authors quantified creatine kinase MB (CK-MB) isoenzyme activity and mass in the serum of 81 uremic and 20 nonuremic (control) patients who had no clinical or electrocardiographic evidence of acute myocardial infarction. CK-MB was quantified by three methods: electrophoresis, the QuiCK-MB (International Immunoassa...

journal_title：American journal of clinical pathology

authors： Medeiros LJ,Schotte D,Gerson B

更新日期：1987-01-01 00:00:00

abstract：:This, to authors' knowledge, is the first report in the United States of Tinea pedis caused by Trichophyton violaceum in a recent Southeast Asian immigrant. Because of the recent entry into this country of refugees from an area of the world where T. violaceum is endemic, this anthropophilic dermatophyte may become a s...

journal_title：American journal of clinical pathology

authors： Fusaro RM,Miller NG,Kelly D

更新日期：1983-07-01 00:00:00

abstract：:The primary role of the surgical pathologist is to diagnose, and then to transmit this information effectively so that it can be used to guide patient management; therefore, the dual roles of the surgical pathologist as a diagnostician and consultant are inextricable. The diagnostic pathologist determines the nature, ...

journal_title：American journal of clinical pathology

authors： Hutter RV

更新日期：1981-03-01 00:00:00

abstract：:The authors describe an unusual variant of alkaline phosphatase (ALP) discovered in a patient with a 90-fold increase in serum ALP. The variant ALP was indistinguishable from the bone isoenzyme when subjected to chemical inhibition, heat inactivation, lectin precipitation, and routine electrophoresis. However, treatme...

journal_title：American journal of clinical pathology

authors： Schreiber WE,Gorecki T,Bernstein V

更新日期：1991-05-01 00:00:00

abstract：OBJECTIVES:The objective of this research was to determine test intervals between intraoperator case reviews to minimize the impact of recall. METHODS:Three pathologists were presented with a group of 120 slides and subsequently challenged with a study set of 120 slides after 2-week and 4-week intervals. The challenge...

journal_title：American journal of clinical pathology

authors： Campbell WS,Talmon GA,Foster KW,Baker JJ,Smith LM,Hinrichs SH

更新日期：2015-03-01 00:00:00

abstract：:Cytopathologic smears and/or imprints of human adrenal cortex (9 cases) and its disorders were examined, including adrenocortical nodule (3 cases), adrenocortical adenoma (23 cases), carcinoma (8 cases), and renal cell carcinoma (6 cases). Immunocytochemistry directed against 3 beta-hydroxysteroid dehydrogenase and ad...

journal_title：American journal of clinical pathology

authors： Sasano H,Shizawa S,Nagura H

更新日期：1995-08-01 00:00:00

abstract：:Clinical data and histologic sections of the liver, including immunohistochemical studies for hepatitis B surface and core antigens, were reviewed in 42 autopsy cases of the acquired immune deficiency syndrome (AIDS). Hepatomegaly, elevation of serum transaminases, and mild elevation of alkaline phosphatase were commo...

journal_title：American journal of clinical pathology

authors： Glasgow BJ,Anders K,Layfield LJ,Steinsapir KD,Gitnick GL,Lewin KJ

更新日期：1985-05-01 00:00:00

abstract：:In 10 cases of Barrett adenocarcinoma, samples from 8 tumor areas (including superficial and deep from peripheral and central areas) and a regional lymph node metastasis were studied for amplification of c-myc, c-erbB-2, and EGFR. We analyzed loss of heterozygosity (LOH) at 3 loci (APC, MCC, and RB) and 2 anonymous mi...

journal_title：American journal of clinical pathology

authors： Owonikoko T,Rees M,Gabbert HE,Sarbia M

更新日期：2002-04-01 00:00:00

abstract：:New federal regulations require review of all available negative gynecologic smears within the previous 5 years for each patient with a current high grade squamous intraepithelial lesion (HGSIL) or above. Two university hospitals retrospectively reviewed all patients who had HGSIL or above and who had prior negative s...

journal_title：American journal of clinical pathology

authors： Allen KA,Zaleski S,Cohen MB

更新日期：1994-01-01 00:00:00

abstract：:Absolute lymphocytosis after nonsurgical trauma was investigated in three patient groups at an acute-care tertiary referral hospital. The first group, with mild-to-moderate trauma, consisted of 64 patients who survived knife wounds to the chest and abdomen. Thirteen of the 64 patients had admission lymphocyte counts g...

journal_title：American journal of clinical pathology

authors： Thommasen HV,Boyko WJ,Montaner JS,Russell JA,Johnson DR,Hogg JC

更新日期：1986-10-01 00:00:00

abstract：:A column chromatographic method for the simultaneous single-eluate isolation of CPK-MB and LDH 1,2 has been evaluated. The method is rapid in that the entire isolation is completed in less than an hour and subsequent analysis can be performed using presently available spectrophotometric methods and reagents without th...

journal_title：American journal of clinical pathology

authors： Lederer WH,Gerstbrein HL,McClintock WC

更新日期：1976-08-01 00:00:00

abstract：:Histiocytosis-X cells were obtained at autopsy from the lungs and lymph nodes of a patient who died of the disseminated infantile form of this disease (Letterer-Siwe disease). The ability of these cells to synthesize and release prostaglandins was investigated in culture, by prelabeling the cell lipids with [14C] arac...

journal_title：American journal of clinical pathology

authors： Gonzalez-Crussi F,Hsueh W,Wiederhold MD

更新日期：1981-02-01 00:00:00

abstract：:Minimal inhibitory concentrations (MICs) of clindamycin, cefoxitin, imipenem, and metronidazole were determined by the E-Test and a reference agar dilution method for 92 gram-negative anaerobic organisms. For 335 MIC pairs, the agreement between the two systems was 80.1%; 60 (17.9%) differed by two or more twofold dil...

journal_title：American journal of clinical pathology

authors： Couroux PR,Massey VE,Schieven BC,Lannigan R,Hussain Z

更新日期：1993-09-01 00:00:00

abstract：:A number of reports have highlighted discrepancies between the DuPont aca and fibrometer-based methods for quantitating plasma fibrinogen levels. Although many authors have suggested that the presence of fibrin(ogen) degradation products are in some way responsible for the discrepancies, no direct test of this hypothe...

journal_title：American journal of clinical pathology

authors： Hoffman M,Greenberg CS

更新日期：1987-10-01 00:00:00

abstract：OBJECTIVES:Preanalytical factors, such as hemolysis, affect many components of a test panel. Machine learning can be used to recognize these patterns, alerting clinicians and laboratories to potentially erroneous results. In particular, machine learning might identify which cases of elevated potassium from a point-of-c...

journal_title：American journal of clinical pathology

authors： Benirschke RC,Gniadek TJ

更新日期：2020-07-07 00:00:00

abstract：:Screening sera for streptococcal antibodies is a useful clinical procedure when recent streptococcal infection requires verification. Presently there are two test kits available that detect five (or more) of the antibodies that may be present. These two screening tests were compared using antistreptolysin O (ASO) and ...

journal_title：American journal of clinical pathology

authors： Tolliver PR,Roe MH

更新日期：1979-08-01 00:00:00

abstract：:Double immunostaining of tissue sections by monoclonal antibodies has been performed using, in immunofluorescence, combinations of reagents conjugated with different fluorochromes. These were monoclonal antibodies directly labeled with phycoerythrin (a new red fluorochrome) and haptenated monoclonal antibodies detecte...

journal_title：American journal of clinical pathology

authors： Pizzolo G,Chilosi M

更新日期：1984-07-01 00:00:00

abstract：:The authors investigated the blast cells obtained from two patients with acute myelofibrosis with the use of recently developed immunochemical and ultrastructural markers. They intended to examine the expression of megakaryoblastic, erythroblastic, myeloblastic, and monoblastic properties in these cells. Respectively,...

journal_title：American journal of clinical pathology

authors： Schreeder MT,Prchal JT,Parmley RT,Carroll AJ,Gewirtz AM,Hoffman R

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study is to determine if the diagnosis of nephrogenic adenoma (NA) can be made on cytologic criteria alone and if pair box gene transcription factor 8 (PAX8) is useful in the diagnosis of NA in daily cytology practice. METHODS:Cytologic features of NA previously described in a literature wer...

journal_title：American journal of clinical pathology

authors： McCroskey Z,Pambuccian SE,Wojcik EM,Barkan GA

更新日期：2016-03-01 00:00:00