Effects of chemotherapy on pathologic and biologic characteristics of locally advanced breast cancer.

abstract：:Complete hydatidiform moles (CHM) and partial hydatidiform moles (PHM) represent different clinicopathologic entities. To obtain prognostic and therapeutic information about both entities, it is important that pathologic classification be as accurate as possible. The distinction of molar pregnancy and an abortus with ...

journal_title：American journal of clinical pathology

authors： Ostrzega N,Phillipson J,Liu P

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVES:To review various anticoagulation therapies and related laboratory monitoring issues, with a focus on factor X-related chromogenic assays. METHODS:A case-based approach is used to review pertinent published literatures and product inserts of anticoagulation drugs and to look back on clinical use of factor X...

journal_title：American journal of clinical pathology

authors： Wool GD,Lu CM,Education Committee of the Academy of Clinical Laboratory Physicians and Scientists.

更新日期：2013-11-01 00:00:00

abstract：:A patient receiving antihypertensive therapy developed acute intravascular hemolysis and died. Hemolysis was due to an immune process associated with antibody to thiazide. Only two other cases have been reported. Thiazide-induced hemolysis appears to be confined to those patients treated concommitantly with methyldopa...

journal_title：American journal of clinical pathology

authors： Beck ML,Cline JF,Hardman JT,Racela LS,Davis JW

更新日期：1984-06-01 00:00:00

abstract：:Although the relationship between pathologic features and clinical outcome is well established in adult adrenocortical neoplasms, the prognostic value of these features in pediatric adrenocortical neoplasms (PACN) is unclear. In a series of PACNs from 54 Brazilian children, the authors retrospectively investigated the...

journal_title：American journal of clinical pathology

authors： Bugg MF,Ribeiro RC,Roberson PK,Lloyd RV,Sandrini R,Silva JB,Epelman S,Shapiro DN,Parham DM

更新日期：1994-05-01 00:00:00

abstract：:We compared a rapid, point-of-care multimarker protocol with a single and serial troponin I (TnI)-only protocol in 5,244 patients admitted to the emergency department with chest pain. The diagnosis of acute myocardial infarction (AMI) was based on a doubling myoglobin level accompanied by at least a 50% increase in th...

journal_title：American journal of clinical pathology

authors： Straface AL,Myers JH,Kirchick HJ,Blick KE

更新日期：2008-05-01 00:00:00

abstract：:To facilitate the differential diagnosis of poorly differentiated metastatic carcinomas of unknown primary site, we evaluated p63 and cytokeratin (CK) 5/6 as immunohistochemical markers for squamous cell carcinomas. The study cases were as follows: squamous cell carcinoma of the lungs, head/neck, esophagus, cervix ute...

journal_title：American journal of clinical pathology

authors： Kaufmann O,Fietze E,Mengs J,Dietel M

更新日期：2001-12-01 00:00:00

abstract：:Twenty cases of inflammatory myofibroblastic tumor (IMT) were studied; 19 involved the lung and 1 the esophagus only. The patients' ages ranged from 3 to 72 years. There were 9 males and 11 females. Involvement of a bronchus was seen in one case and of mediastinal structures in four. Chest pain and dyspnea were common...

journal_title：American journal of clinical pathology

authors： Pettinato G,Manivel JC,De Rosa N,Dehner LP

更新日期：1990-11-01 00:00:00

abstract：:The authors describe 11 patients with non-Hodgkin's lymphoma arising in the nasal cavity or paranasal sinuses. Seven were men and four were women. The median age of the women was 76 years; the median age of the men was 45 years. The most common presenting symptoms were nasal obstruction and unilateral facial swelling....

journal_title：American journal of clinical pathology

authors： Frierson HF Jr,Mills SE,Innes DJ Jr

更新日期：1984-06-01 00:00:00

abstract：:Protease inhibitor serpin-B2 (plasminogen activator inhibitor-2 [PAI-2]) protects pRb from degradation in human papillomavirus (HPV)-18+ HeLa cells. Our objective was to assess whether the pRb-mediated HPV-suppressive effect of PAI-2 in cancer cell lines has implications in the outcome of HPV infections. Cervical biop...

journal_title：American journal of clinical pathology

authors： Syrjänen S,Naud P,Sarian L,Derchain S,Roteli-Martins C,Longatto-Filho A,Tatti S,Branca M,Erzen M,Hammes LS,Costa S,Syrjänen K

更新日期：2009-12-01 00:00:00

abstract：:p53 protein expression was evaluated in a series of 204 primary colorectal adenocarcinomas by immunohistochemistry using frozen tissue sections and monoclonal antibody DO-7. Nuclear staining of more than 5% of neoplastic cells was observed in 124 (60.8%) adenocarcinomas, which were classified as p53 positive. p53 immu...

journal_title：American journal of clinical pathology

authors： Lanza G Jr,Maestri I,Dubini A,Gafa R,Santini A,Ferretti S,Cavazzini L

更新日期：1996-05-01 00:00:00

abstract：:We sought to determine the sensitivity and specificity of immunohistochemistry using the TORDJI-22 MoAb (BioGenex, San Ramon, Calif), which is specific for the C-100 protein of the hepatitis C virus, compared with reverse transcriptase-polymerase chain reaction (RT-PCR) of tissue for viral RNA. RT-PCR had been perform...

journal_title：American journal of clinical pathology

authors： Brody RI,Eng S,Melamed J,Mizrachi H,Schneider RJ,Tobias H,Teperman LW,Theise ND

更新日期：1998-07-01 00:00:00

abstract：:Four cases of acute myelofibrosis are contrasted to three cases of acute megakaryocytic leukemia. The cases were clinically indistinguishable. Light microscopic examination of hematoxylin and eosin-stained bone marrow biopsy specimens from the cases of acute myelofibrosis showed a trilinear proliferation of mature and...

journal_title：American journal of clinical pathology

authors： Hruban RH,Kuhajda FP,Mann RB

更新日期：1987-11-01 00:00:00

abstract：:Estrogen receptor (ER), progesterone receptor (PR), and c-ERBB2 (HER2/neu) are therapeutically and prognostically important markers in the management of breast carcinoma. They are not always analyzed in distant metastatic and locally recurrent breast cancers. We compared immunohistochemical expression in a series of p...

journal_title：American journal of clinical pathology

authors： Idirisinghe PK,Thike AA,Cheok PY,Tse GM,Lui PC,Fook-Chong S,Wong NS,Tan PH

更新日期：2010-03-01 00:00:00

abstract：:There are few studies that examine prevalence, quantity, and cellular proclivity of latent human herpesvirus 6 (HHV-6) in healthy populations. We examined 69 tonsils with paired blood specimens from children without evidence of acute infection. By polymerase chain reaction (PCR), HHV-6 was detected at low levels in 10...

journal_title：American journal of clinical pathology

authors： Roush KS,Domiati-Saad RK,Margraf LR,Krisher K,Scheuermann RH,Rogers BB,Dawson DB

更新日期：2001-11-01 00:00:00

abstract：:In a computerized case registry, containing 220 cases of sinus histiocytosis with massive lymphadenopathy (SHML), 23 patients were identified with clinical or routine laboratory findings suggestive or diagnostic of immune dysfunction. We divided the abnormalities into hematologic autoantibodies (nine patients), glomer...

journal_title：American journal of clinical pathology

authors： Foucar E,Rosai J,Dorfman RF,Eyman JM

更新日期：1984-11-01 00:00:00

abstract：:CD45/side scatter (SS) gating is widely used for isolating blasts by flow cytometry (FC). However, other cells contaminate the "blast gate" (BG); CD45/SS gating is thus imprecise, particularly when there are few blasts. We studied the BG contents in 21 myelodysplastic syndromes (MDSs), 14 myeloproliferative neoplasms ...

journal_title：American journal of clinical pathology

authors： Harrington AM,Olteanu H,Kroft SH

更新日期：2012-05-01 00:00:00

abstract：:Cellular proliferation is being evaluated as an independent prognostic indicator in a variety of tumors, including non-Hodgkin's lymphomas (NHL). Although the labeling index (LI), using either tritiated thymidine or monoclonal antibodies to bromodeoxyuridine, is considered to be the gold standard of cell kinetic measu...

journal_title：American journal of clinical pathology

authors： Sebo TJ,Roche PC,Witzig TE,Kurtin PJ

更新日期：1993-06-01 00:00:00

abstract：:An acquired circulating inhibitor to Factor VIII:C was found in a 27-year-old postpartum woman who presented with ecchymoses and hematomas. Postpartum Factor VIII:C inhibitors can clinically manifest with signs and symptoms not unlike those in a classic hemophiliac. The natural history of this inhibitor is typically o...

journal_title：American journal of clinical pathology

authors： Shitamoto BS,Leslie KO,Galloway WB

更新日期：1982-11-01 00:00:00

abstract：:The international sensitivity index (ISI) calibration of point-of-care-test (POCT) prothrombin time (PT) whole blood monitors is complex, requiring manual PT testing of 60 patients' and 20 healthy subjects' plasma samples. The possibility of reducing these numbers was studied by a Monte Carlo Bootstrap study for 2 POC...

journal_title：American journal of clinical pathology

authors： Poller L,Keown M,Chauhan N,van den Besselaar AM,Tripodi A,Jespersen J,Shiach C

更新日期：2002-06-01 00:00:00

abstract：:Blood glucose results for 2,601 specimens obtained at multiphasic health examination, divided into three age groups, were analyzed using probability plot paper. Two straight lines could be fitted to each distribution. The assumption was made that the lower lines correspond to "normal-healthy" persons, whereas the uppe...

journal_title：American journal of clinical pathology

authors： Morgenstern NL,Shearn MA

更新日期：1981-08-01 00:00:00

abstract：:Eosinophils are normally absent from the urine. Their presence has been associated with a variety of clinical conditions affecting the kidney or urinary tract. The authors examined the clinical significance and eosinophils, in particular, for acute interstitial nephritis. ...

journal_title：American journal of clinical pathology

authors： Corwin HL,Haber MH

更新日期：1987-10-01 00:00:00

abstract：:Mucocele-like tumors of the breast originally were reported by Rosen in 1986 as benign lesions that histologically resembled colloid carcinoma of the breast. The authors document two cases of mucocele-like tumors to illustrate the difficulty in separating these lesions from colloid carcinoma on the basis of fine-needl...

journal_title：American journal of clinical pathology

authors： Bhargava V,Miller TR,Cohen MB

更新日期：1991-06-01 00:00:00

abstract：:Cell counter-based formulas have been used in the differential diagnosis of microcytic anemia. The measurement of RBC subpopulations is now available on the Sysmex XE 5000 analyzer (Sysmex, Kobe, Japan). We describe the new formulas: % microcytic - % hypochromic; and % microcytic - % hypochromic - red cell distributio...

journal_title：American journal of clinical pathology

authors： Urrechaga E,Borque L,Escanero JF

更新日期：2011-03-01 00:00:00

abstract：:Peripheral blood mononuclear cells from pemphigus vulgaris and bullous pemphigoid patients produced antiepithelial antibodies in a pokeweed mitogen-stimulated in vitro cell culture system. Antiintercellular substance (ICS) antibodies were detected in supernatants of cell cultures from four of four pemphigus vulgaris p...

journal_title：American journal of clinical pathology

authors： Fitzmaurice M,Deodhar SD

更新日期：1984-05-01 00:00:00

abstract：:A flow cytometric technic was developed to detect platelet surface-bound immunoglobulin in patients with thrombocytopenia. Elevated platelet surface IgG and/or IgM was detected in 90.9% of patients with immune thrombocytopenia purpura (ITP). False positive results occurred in 9.3% of patients with nonimmune thrombocyt...

journal_title：American journal of clinical pathology

authors： Rosenfeld CS,Nichols G,Bodensteiner DC

更新日期：1987-04-01 00:00:00

abstract：:The measurement of beta-thromboglobulin (BTG) and platelet lactic dehydrogenase (LDH) as markers for alpha-granule release and platelet lysis, respectively, has been reported to correlate with the amount of damage incurred during the preparation and storage of platelet concentrates. We compared the concentrations of t...

journal_title：American journal of clinical pathology

authors： Kalmin ND,Wilson MJ,Liles BA

更新日期：1983-06-01 00:00:00

abstract：:In a university-affiliated community hospital, medical records of 58 patients on whom the intact parathyroid hormone immunoassay (I-PTH) and 29 patients on whom both the carboxyl terminal PTH(C-PTH) and I-PTH ordered by physicians were reviewed to determine the reasons for requesting these tests. Reasons for ordering ...

journal_title：American journal of clinical pathology

authors： Juan D,Wehrmeister J

更新日期：1982-06-01 00:00:00

abstract：:In-situ and microinvasive adenocarcinoma of the uterine cervix. A clinical, cytologic and histologic study of 14 cases. Am J Clin Pathol 64: 155-70, 1975. The clinicopathologic features of 14 cases of in-situ and microinvasive adenocarcinoma of the cervix, encountered during the period 1961-1974, form the basis of thi...

journal_title：American journal of clinical pathology

authors： Qizilbash AH

更新日期：1975-08-01 00:00:00

abstract：:Platelet-derived growth factors (PDGFs) exert their biologic function by binding to 3 different tyrosine kinase receptor isoforms. Especially the PDGF-alpha alpha receptor binds PDGF proteins with high specificity, which results in growth stimulation. The expression of the receptor and its ligand was studied in human ...

journal_title：American journal of clinical pathology

authors： Sulzbacher I,Birner P,Träxler M,Marberger M,Haitel A

更新日期：2003-07-01 00:00:00

abstract：:Hemizygous TP53 gene deletion is the most important adverse risk factor in chronic lymphocytic leukemia (CLL), but its relationship with p53 protein expression is unclear. We investigated 110 CLL cases and correlated nuclear p53 protein immunoreactivity with TP53 gene deletion status and other CLL-associated genetic r...

journal_title：American journal of clinical pathology

authors： Chang H,Jiang AM,Qi CX

更新日期：2010-01-01 00:00:00