DNA analysis (ploidy) of molar pregnancies with image analysis on paraffin tissue sections.

abstract：:Three brands of blood collection tubes were studied for their influence on the prothrombin time (PT) and international sensitivity index (ISI) for 5 commercial thromboplastin reagents. With all reagents, PTs were shorter in Vacutainer (Becton Dickinson Vacutainer Systems, Plymouth, England) samples than in S-Monovette...

journal_title：American journal of clinical pathology

authors： van den Besselaar AM,Hoekstra MM,Witteveen E,Didden JH,van der Meer FJ

更新日期：2007-05-01 00:00:00

abstract：:Uterine tumors with histologic resemblances to ovarian sex-cord tumors were encountered in 14 women in the fourth to sixth decades of life, most of whom had abnormal vaginal bleeding and enlarged uteri suggesting leiomyomas. The tumors in six cases (Group I) were identical to one or another form of well-recognized end...

journal_title：American journal of clinical pathology

authors： Clement PB,Scully RE

更新日期：1976-09-01 00:00:00

abstract：:Human papillomaviruses (HPVs) are associated with benign and malignant neoplasms of the cervix. One of the criteria for their etiologic role requires an assessment of whether virtually all or only a small fraction of lesions contain viral genomes. DNA preparations from colposcopically directed punch biopsies of cervic...

journal_title：American journal of clinical pathology

authors： Tham KM,Chow VT,Singh P,Tock EP,Ching KC,Lim-Tan SK,Sng IT,Bernard HU

更新日期：1991-05-01 00:00:00

abstract：:One of the functions of von Willebrand factor (vWF) is to serve as a carrier of clotting factor VIII (FVIII). Deficiency of this function results in the von Willebrand disease (vWD) variant type 2N, which resembles hemophilia A. We describe a new sandwich enzyme-linked immunosorbent assay (ELISA) to study the ability ...

journal_title：American journal of clinical pathology

authors： Casonato A,Pontara E,Zerbinati P,Zucchetto A,Girolami A

更新日期：1998-03-01 00:00:00

abstract：:A practical acidimetric assay for penicillinase production using penicillin and phenol red impregnated in paper discs was developed. Blank discs were first impregnated with buffered penicillin G and, after drying, with 1% phenol red. For use, a disc was added to a bacterial suspension made in saline solution. A yellow...

journal_title：American journal of clinical pathology

authors： Tu KK,Jorgensen JH,Stratton CW

更新日期：1981-04-01 00:00:00

abstract：:Determination of breast cancer estrogen receptor (ER) status as a predictor of tumor response to adjuvant endocrine therapy remains a mainstay of breast cancer management. Recent second generation anti-ER antibodies and new epitope retrieval methods have produced paraffin-based immunohistochemical results that correla...

journal_title：American journal of clinical pathology

authors： Nichols GE,Frierson HF Jr,Boyd JC,Hanigan MH

更新日期：1996-09-01 00:00:00

abstract：:Pathologists are expected to accurately diagnose increasingly smaller breast carcinomas. Correct classification (ie, lobular vs ductal or in situ vs invasive) directly affects subsequent management, especially when the focus is near a surgical margin or present in a needle core biopsy and is further challenging if the...

journal_title：American journal of clinical pathology

authors： Ross DS,Liu YF,Pipa J,Shin SJ

更新日期：2013-01-01 00:00:00

abstract：:An unusual case of acute myelomonocytic leukemia (AMML) in an 81-year-old man is described. Ultrastructural examination revealed the presence of distinct Auer bodies, which commonly are found in acute promyelocytic leukemia (APL). The Auer bodies had a splinterlike appearance with a distinct tubular substructure. The ...

journal_title：American journal of clinical pathology

authors： Payne CM,Harrow EJ

更新日期：1983-08-01 00:00:00

abstract：OBJECTIVES:Certain laboratory tests are critical for patient care and must be communicated rapidly. Professional societies have developed guidelines for reporting of "critical values" and significant or unexpected surgical pathology findings. Urgent diagnoses requiring rapid reporting include new or unexpected diagnose...

journal_title：American journal of clinical pathology

authors： Layfield LJ,Schnabel JL

更新日期：2014-12-01 00:00:00

abstract：:Antiphospholipid antibodies (aPLs) have been implicated in atherogenesis. We studied 344 patients with acute coronary syndromes; approximately 40% were aPL+ in 1 or more tests and 60% aPL-. In 215 patients, coronary artery disease (CAD) was angiographically documented, with 43.7% positive for aPL vs 34.9% of patients ...

journal_title：American journal of clinical pathology

authors： Greco TP,Conti-Kelly AM,Greco T Jr,Doyle R,Matsuura E,Anthony JR,Lopez LR

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVES:Universal screening of upper tract urothelial carcinoma (UTUC) for Lynch syndrome by mismatch repair (MMR) protein immunohistochemistry (IHC) has been recommended by some investigators. Herein, we assess this recommendation retrospectively by simulating its performance on a retrospective, unselected cohort o...

journal_title：American journal of clinical pathology

authors： Gayhart MG,Johnson N,Paul A,Quillin JM,Hampton LJ,Idowu MO,Smith SC

更新日期：2020-11-04 00:00:00

abstract：:Bleeding problems are symptomatic of platelet delta-storage pool diseases (SPDs) such as Hermansky-Pudlak syndrome. Although at present no cure is available for delta-SPD, early diagnosis is of great importance for prophylactic and supportive treatment. This study tested the usefulness of a flow cytometric assay for p...

journal_title：American journal of clinical pathology

authors： Maurer-Spurej E,Pittendreigh C,Wu JK

更新日期：2007-04-01 00:00:00

abstract：:The professional activities of anatomic and clinical pathologists involve, to a large extent, management issues. To evaluate the management training received by pathology residents, the authors surveyed pathology residency training programs in the United States. Responses were collected from 138 of 187 programs (73.8%...

journal_title：American journal of clinical pathology

authors： Brugnara C,Fenton T,Winkelman JW

更新日期：1994-05-01 00:00:00

abstract：:Twenty-four cases of a lesion characterized by unlined spaces in the colorectal lamina propria are presented. While lesions such as this have been reported previously as "lipomatosis" of the colon, histochemical and ultrastructural examination reveals that they are not, in fact, composed of adipocytes. It appears that...

journal_title：American journal of clinical pathology

authors： Snover DC,Sandstad J,Hutton S

更新日期：1985-11-01 00:00:00

abstract：:Four acid hydrolases, acid phosphatase (AP), alpha-naphthyl acetate esterase (ANAE), beta-glucuronidase, and N-acetyl-beta-glucosaminidase, were determined cytochemically in peripheral blood lymphocytes from 50 patients with B and T chronic lymphocytic and prolymphocytic leukemias (CLL, PLL) and related disorders. Str...

journal_title：American journal of clinical pathology

authors： Crockard A,Chalmers D,Matutes E,Catovsky D

更新日期：1982-10-01 00:00:00

abstract：:Platelet-derived growth factors (PDGFs) exert their biologic function by binding to 3 different tyrosine kinase receptor isoforms. Especially the PDGF-alpha alpha receptor binds PDGF proteins with high specificity, which results in growth stimulation. The expression of the receptor and its ligand was studied in human ...

journal_title：American journal of clinical pathology

authors： Sulzbacher I,Birner P,Träxler M,Marberger M,Haitel A

更新日期：2003-07-01 00:00:00

abstract：:We evaluated a more efficient method of processing liquid-based cervical cytology specimens for human papillomavirus (HPV) DNA testing by Hybrid Capture II (HCII). Aliquots were made from 701 specimens in the following sequence: 4.0, 2.0, 1.0, 0.5, and 1.5 mL. The 4.0-mL aliquot was processed by the standard method (S...

journal_title：American journal of clinical pathology

authors： Castle PE,Garcia-Meijide M,Holladay EB,Chuke R,Payne J,Long A,Siefers H,Demuth F,Lorincz AT

更新日期：2005-02-01 00:00:00

abstract：:Specific radioimmunoassays, sensitive to plasma levels of less than 1% of normal, were developed for protein C and Factor X. In 31 normal subjects, mean plasma antigen levels were as follows: protein C, 3.23 +/- 0.79 microgram/mL (2 SD); Factor X, 7.74 +/- 1.81 microgram/mL. In patient son chronic warfarin therapy, pr...

journal_title：American journal of clinical pathology

authors： Epstein DJ,Bergum PW,Bajaj SP,Rapaport SI

更新日期：1984-11-01 00:00:00

abstract：:A case of fetal demise and maternal recovery after acetaminophen overdose is presented, to our knowledge the first reported. Fetal liver and maternal serum concentrations indicate overdose to be the cause of fetal death. Maternal disseminated intravascular coagulation (DIC) may have been related to maternal acetaminop...

journal_title：American journal of clinical pathology

authors： Haibach H,Akhter JE,Muscato MS,Cary PL,Hoffmann MF

更新日期：1984-08-01 00:00:00

abstract：:We compared the morphologic findings of different types of marginal zone B-cell lymphoma (MZL) involving the bone marrow (BM), including 18 splenic (SMZL), 6 extranodal (mucosa-associated lymphoid tissue lymphoma), and 6 nodal cases. The median percentage of BM involvement was 15%, and multiple overlapping patterns of...

journal_title：American journal of clinical pathology

authors： Inamdar KV,Medeiros LJ,Jorgensen JL,Amin HM,Schlette EJ

更新日期：2008-05-01 00:00:00

abstract：:Seven monoclonal antibodies of rat origin were generated against human epidermal keratins and were assayed by immunoblot and by immunoperoxidase staining of frozen sections from various human epithelial tissues. By immunoblotting, the antibodies recognized two different subsets of high molecular weight cytokeratin pol...

journal_title：American journal of clinical pathology

authors： Chin NW,Lai BT,Lanks KW

更新日期：1988-03-01 00:00:00

abstract：:By application of combined structural and functional analyses, most lymphoid neoplasms may be categorized as of T- or B-cell origin. T lymphocyte neoplasms include types of acute and chronic lymphocytic leukemias, certain cutaneous and node-based lymphomas, and lymphomas of thymocytes (convoluted lymphocytic lymphomas...

journal_title：American journal of clinical pathology

authors： Collins RD,Waldron JA,Glick AD

更新日期：1979-10-01 00:00:00

abstract：:Reported is a case of lymphoma which was preceded for nine years by an apparently reactive lymphadenopathy. Original slides of the multiple lymphoid tissue samples are reviewed, with emphasis on the gradually increasing numbers of mitoses, atypical histiocytes, and eosinophils, suggestive of malignant transformation. ...

journal_title：American journal of clinical pathology

authors： Hyland CH,Murad TM,Dismukes WE

更新日期：1977-11-01 00:00:00

abstract：:Neoplastic transformation of epithelial cell sis commonly associated with altered synthesis of mucin glycoproteins. Few studies have been performed on the correlation between MUC 1 expression and pancreatic carcinoma using immunohistochemical methods. We compared the patterns of MUC 1 expression in normal pancreatic t...

journal_title：American journal of clinical pathology

authors： Monges GM,Mathoulin-Portier MP,Acres RB,Houvenaeghel GF,Giovannini MF,Seitz JF,Bardou VJ,Payan MJ,Olive D

更新日期：1999-11-01 00:00:00

abstract：:The authors studied the effect of averaging replicated assays of Factor IX coagulation activity and Factor IX antigen on each plasma specimen in improving the ability to detect carriers of hemophilia B. The improvement resulting from this procedure is particularly marked in tests depending on the linear regression of ...

journal_title：American journal of clinical pathology

authors： Lipworth L,Tiarks CY,Rice CA,Pechet L

更新日期：1979-12-01 00:00:00

abstract：:After several transfusions with D-negative blood, an O Rh-negative women was apparently sensitized to the C and D antigens. In her prenatal workup, it became evident that she had in fact not been sensitized to D but to G, which initially appeared as anti-D plus anti-C. This sensitization pattern is an unusual occurren...

journal_title：American journal of clinical pathology

authors： Yesus YW,Akhter JE

更新日期：1985-12-01 00:00:00

abstract：:A single oral dose of tetracycline deposits in bone and is readily identified with fluorescence microscopy. Two such time-spaced labels can be used to determine bone dynamic features. This is as accurate as conventional three-day labeling periods. The simplicity, improved compliance, and substantial reduction in time ...

journal_title：American journal of clinical pathology

authors： Sherrard DJ,Maloney NA

更新日期：1989-06-01 00:00:00

abstract：:Myxomatous degeneration of the mitral valve is a disease of unknown etiology that is associated with many ominous complications. A case in which non-bacterial thrombotic endocarditis, superimposed on a myxomatous mitral valve, resulted in systemic embolization to the brain, heart, and kidney is presented. The purpose ...

journal_title：American journal of clinical pathology

authors： Geyer SJ,Franzini DA

更新日期：1979-09-01 00:00:00

abstract：:Mycobacteriology results of the CAP proficiency testing programs are reviewed for the years 1975-1981. Survey participants have shown a continuing and improving ability to isolate and identify Mycobacterium tuberculosis, nontuberculous mycobacteria, and to identify acid-fast bacteria in stain preparations. ...

journal_title：American journal of clinical pathology

authors： Dreskin RB,Sommers HM,Edson D

更新日期：1982-10-01 00:00:00

abstract：:A patient with prolymphocytic leukemia was immunophenotyped by whole blood and Ficoll-Hypaque methods. Discordance was noted between the two methods, especially for the HLE1, B1, I2, and T1B monoclonal markers. The disparity in results reflected the use of 15 X 10(6) cells versus 1 X 10(6) cells per reaction tube. Thi...

journal_title：American journal of clinical pathology

authors： Warzynski MJ,Podgurski AE,Boldt DM,Hetzel PC

更新日期：1989-02-01 00:00:00