CD5+ follicle center lymphoma. Immunophenotyping detects a unique subset of "floral" follicular lymphoma.

abstract：:Extramammary Paget disease (EPD) is an uncommon cutaneous malignant neoplasm that arises in areas rich in apocrine glands (perineum, vulva, and axilla). Apocrine gland origin or apocrine differentiation of cells of EPD has been suggested. Estrongen, progesterone, and androgen hormone receptors have been reported to ex...

journal_title：American journal of clinical pathology

authors： Diaz de Leon E,Carcangiu ML,Prieto VG,McCue PA,Burchette JL,To G,Norris BA,Kovatich AJ,Sanchez RL,Krigman HR,Gatalica Z

更新日期：2000-04-01 00:00:00

abstract：:An automated fluorescent immunoassay system (FIAX) was compared with complement fixation (CF) for measuring antibodies to cytomegalovirus (CMV) and herpes simplex virus (HSV) in clinical specimens. Compared with CF the specificity of FIAX (ability to detect a negative titer) was 95% for CMV and 92% for HSV. The sensit...

journal_title：American journal of clinical pathology

authors： Friedman HM,Tustin NB,Hitchings MM,Plotkin SA

更新日期：1981-09-01 00:00:00

abstract：:We report 8 cases of hepatosplenic T-cell lymphoma (HSTCL) involving bone marrow and correlate histologic findings with disease progression. Immunophenotypic analysis demonstrated mature, aberrant gamma/delta T-cell immunophenotypes. Isochromosome 7q was identified in 4 cases; 1 case showed the t(7;14)(q34;q13). Seven...

journal_title：American journal of clinical pathology

authors： Vega F,Medeiros LJ,Bueso-Ramos C,Jones D,Lai R,Luthra R,Abruzzo LV

更新日期：2001-09-01 00:00:00

abstract：:Mucocele-like lesion (MLL) is a rare mucinous lesion of the breast with highly variable upgrade rates to atypia or malignancy on excision. This spectrum of data has led to differing opinions on the need for surgical excision. We evaluated 50 core biopsy specimens diagnosed as having MLLs and correlated the findings wi...

journal_title：American journal of clinical pathology

authors： Sutton B,Davion S,Feldman M,Siziopikou K,Mendelson E,Sullivan M

更新日期：2012-12-01 00:00:00

abstract：:An anti-serum against human neuron-specific enolase (NSE), raised in sheep, has been characterized and used for immunocytochemical localization of NSE in paraffin sections of normal tissues and lung cancers. Of the small cell carcinomas (SCC), 69 out of 99 (70%) cases stained with the anti-serum. Maltreated biopsies s...

journal_title：American journal of clinical pathology

authors： Bergh J,Esscher T,Steinholtz L,Nilsson K,Påhlman S

更新日期：1985-07-01 00:00:00

abstract：:Four cases of acute myelofibrosis are contrasted to three cases of acute megakaryocytic leukemia. The cases were clinically indistinguishable. Light microscopic examination of hematoxylin and eosin-stained bone marrow biopsy specimens from the cases of acute myelofibrosis showed a trilinear proliferation of mature and...

journal_title：American journal of clinical pathology

authors： Hruban RH,Kuhajda FP,Mann RB

更新日期：1987-11-01 00:00:00

abstract：:Venography was performed on fifty-six patients suspected of having deep venous thrombosis (DVT) of the legs. The accuracy of the D-dimer measurement in plasma using two latex tests and an enzyme-linked immunosorbent assay (ELISA) was compared with that of usual determination of total fibrin(ogen) degradation products ...

journal_title：American journal of clinical pathology

authors： Bounameaux H,Schneider PA,Reber G,de Moerloose P,Krahenbuhl B

更新日期：1989-01-01 00:00:00

abstract：:We performed a retrospective clinicopathologic study on sequential biopsy specimens from 90 patients with Philadelphia chromosome-positive chronic myelogenous leukemia to study therapy-specific effects of busulfan (28 patients), hydroxyurea (32 patients), and interferon-alfa (IFN-alfa; 30 patients). Bone marrow specim...

journal_title：American journal of clinical pathology

authors： Thiele J,Kvasnicka HM,Schmitt-Graeff A,Bundschuh S,Biermann T,Roessler G,Wasmus M,Diehl V,Zankovich R,Schaefer HE

更新日期：2000-07-01 00:00:00

abstract：:Evaluation of blood cells to determine immunologic status is becoming an important clinical application of flow cytometric analysis. For a wider use of immunophenotyping technology in clinical laboratories, the authors developed a rapid method to detect monoclonal antibody-labeled cells using forward light scatter/abs...

journal_title：American journal of clinical pathology

authors： Kim YR,Paseltiner L,Kling G,Yeh CK

更新日期：1992-03-01 00:00:00

abstract：:Platelet refractoriness is caused by HLA antibodies and platelet-specific antibodies. Current methods used to detect antiplatelet antibodies have limitations. Solid phase red cell adherence (SPRCA) lacks sensitivity and requires a second assay using chloroquine-treated intact platelets to specify the response due to a...

journal_title：American journal of clinical pathology

authors： Vongchan P,Nawarawong W,Linhardt RJ

更新日期：2008-09-01 00:00:00

abstract：:This article deals with and formalizes 2 notions common to the practice of pathology. The first is that the number of lymph nodes found positive for metastasis relates directly to the total number of lymph nodes examined. The second is that for any patient, there is a chance that the absence of lymph node metastases i...

journal_title：American journal of clinical pathology

authors： Vollmer RT

更新日期：2005-05-01 00:00:00

abstract：:Tissue specimens from a series of 46 hepatic tumors occurring in young female oral contraceptive users were tested for alpha1-antitrypsin deposition, utilizing immunocytochemical and histochemical methods. In two instances serum alpha1-antitrypsin phenotyping was also performed. Immunoreactive alpha1-antitrypsin depos...

journal_title：American journal of clinical pathology

authors： Palmer PE,Christopherson WM,Wolfe HJ

更新日期：1977-12-01 00:00:00

abstract：:Three activated partial thromboplastin time (APTT) reagent test systems, General Diagnostics Automated APTT, American Dade Actin FS, and Pacific Hemostasis (Thromboscreen KAPTT) reagent, containing different activators for the APTT assay, were evaluated for their precision and sensitivity to factor deficiencies in the...

journal_title：American journal of clinical pathology

authors： Turi DC,Peerschke EI

更新日期：1986-01-01 00:00:00

abstract：:We studied 68 sporadic colorectal carcinomas (CRCs) with medullary features (MCRCs) and compared them with 35 poorly differentiated purely "enteric" CRCs (ECRCs) and 15 purely neuroendocrine carcinomas (NECs) of grades II and III, all in patients lacking a family history of CRC. Potential clinicopathologic differences...

journal_title：American journal of clinical pathology

authors： Wick MR,Vitsky JL,Ritter JH,Swanson PE,Mills SE

更新日期：2005-01-01 00:00:00

abstract：Objectives:To determine whether V H family usage in B-cell lymphoproliferative disorders can be deduced from polymerase chain reaction (PCR) product-length information obtained through the BIOMED-2 (Invivoscribe, San Diego, CA) clonality assay. Methods:We develop an algorithm that uses the sizing information of the BI...

journal_title：American journal of clinical pathology

authors： McDonald TJ,Kuo L,Kuo FC

更新日期：2017-06-01 00:00:00

abstract：:A method using the RNA polymerase chain reaction technique to diagnose infection retrospectively using single-stranded RNA enteroviruses in paraffin-embedded tissue blocks is reported. This method takes advantage of extreme sequence conservation in the 5' untranslated region of the enteroviral genome and uses two roun...

journal_title：American journal of clinical pathology

authors： Redline RW,Genest DR,Tycko B

更新日期：1991-11-01 00:00:00

abstract：:The authors investigated assays for free protein S (ProS) antigen, total ProS antigen, and ProS crossed immunoelectrophoresis (CIEP) in the diagnosis of type 1 inherited ProS deficiency. Accurate measurement of the hemostatically important free ProS required showing that, on each specimen, precipitation of the C4b-bin...

journal_title：American journal of clinical pathology

authors： Edson JR,Vogt JM,Huesman DA

更新日期：1990-08-01 00:00:00

abstract：:A case of fetal demise and maternal recovery after acetaminophen overdose is presented, to our knowledge the first reported. Fetal liver and maternal serum concentrations indicate overdose to be the cause of fetal death. Maternal disseminated intravascular coagulation (DIC) may have been related to maternal acetaminop...

journal_title：American journal of clinical pathology

authors： Haibach H,Akhter JE,Muscato MS,Cary PL,Hoffmann MF

更新日期：1984-08-01 00:00:00

abstract：Objective:T-cell large granular lymphocytic (T-LGL) leukemia is associated with B-cell lymphomas (BCLs), especially small BCLs. We aimed to explore and expand upon its association with BCLs. Methods:We retrospectively studied clinicopathologic features of T-LGL leukemia patients with coexisting BCL from January 2001 t...

journal_title：American journal of clinical pathology

authors： Goyal T,Thakral B,Wang SA,Bueso-Ramos CE,Shi M,Jevremovic D,Morice WG,Zhang QY,George TI,Foucar KK,Bhattacharyya S,Bagg A,Rogers HJ,Bodo J,Durkin L,Hsi ED

更新日期：2018-01-29 00:00:00

abstract：:A case of adenocarcinoma of the small bowel arising in pre-existing transmural ileitis (Crohn's disease) is reported and 28 previously reported cases are reviewed. Carcinoma associated with transmural enteritis occurs more often in the distal ileum, in younger patients, and in more males than expected from published d...

journal_title：American journal of clinical pathology

authors： Savage RA,Farmer RG,Hawk WA

更新日期：1975-02-01 00:00:00

abstract：:The cell cycle consists of an initial growth phase (G1), DNA replication (S), a gap phase (G2), and mitosis (M), after which the cell may differentiate or enter the resting state (G0). The cycle is driven by a number of positive and negative regulatory phosphorylation and dephosphorylation events, involving protein ki...

journal_title：American journal of clinical pathology

authors： Dictor M,Ehinger M,Mertens F,Akervall J,Wennerberg J

更新日期：1999-07-01 00:00:00

abstract：:We describe 13 cases in which the submucosa and muscularis mucosae of the gastrointestinal tract exhibited a focal or diffuse increase of elastin fibers. This elastosis or elastofibromatous change most commonly manifested as a colonic polyp and usually was found during screening colonoscopy. Gastric and small intestin...

journal_title：American journal of clinical pathology

authors： Hobbs CM,Burch DM,Sobin LH

更新日期：2004-08-01 00:00:00

abstract：:A new hemolytic plate method for the functional assessment of alternative-pathway complement activity is described. The plates are easy to prepare and the method simple to perform. Analysis of 23 normal serum samples showed a mean lysis diameter of 4.1 +/- 0.2 mm (1 standard deviation). ...

journal_title：American journal of clinical pathology

authors： Fong JS,Renaud L

更新日期：1978-02-01 00:00:00

abstract：:The authors studied the performance of four measures of laboratory turnaround time: the mean, median, 90th percentile, and proportion of tests reported within a predetermined cut-off interval (proportion of acceptable tests [PAT]). Measures were examined with the use of turnaround time data from 11,070 stat partial th...

journal_title：American journal of clinical pathology

authors： Valenstein PN,Emancipator K

更新日期：1989-04-01 00:00:00

abstract：:While plasmacytosis is a common occurrence in early post-bone marrow transplantation biopsy specimens, the significance of plasma cells in such specimens from patients with multiple myeloma (MM) is unknown. We attempted to retrospectively determine, by morphologic assessment of plasma cell percentage, immunohistologic...

journal_title：American journal of clinical pathology

authors： Maia DM,Kell DL,Goates JJ,Warnke RA

更新日期：1997-06-01 00:00:00

abstract：:We reviewed the cytologic features of 20 adrenal cortical carcinomas (ACCs; 9 primary and 11 metastatic) from 19 patients and highlighted diagnostic pitfalls. The mean size of primary ACCs was 11.9 cm, and that of metastatic ACCs was 3.0 cm. The metastatic sites were liver, lung, lymph node, soft tissue, and bone. Pri...

journal_title：American journal of clinical pathology

authors： Ren R,Guo M,Sneige N,Moran CA,Gong Y

更新日期：2006-09-01 00:00:00

abstract：:We studied the role of ischemia-modified albumin (IMA) with standard biomarkers (myoglobin, creatine kinase-MB [CK-MB], troponin I [TnI]) in assessment of 200 patients with suspected myocardial ischemia admitted to the emergency department. Every case was reviewed by a cardiologist. A clinical diagnosis of ischemia wa...

journal_title：American journal of clinical pathology

authors： Anwaruddin S,Januzzi JL Jr,Baggish AL,Lewandrowski EL,Lewandrowski KB

更新日期：2005-01-01 00:00:00

abstract：:Eosinophils are normally absent from the urine. Their presence has been associated with a variety of clinical conditions affecting the kidney or urinary tract. The authors examined the clinical significance and eosinophils, in particular, for acute interstitial nephritis. ...

journal_title：American journal of clinical pathology

authors： Corwin HL,Haber MH

更新日期：1987-10-01 00:00:00

abstract：:The primary role of the surgical pathologist is to diagnose, and then to transmit this information effectively so that it can be used to guide patient management; therefore, the dual roles of the surgical pathologist as a diagnostician and consultant are inextricable. The diagnostic pathologist determines the nature, ...

journal_title：American journal of clinical pathology

authors： Hutter RV

更新日期：1981-03-01 00:00:00

abstract：:This paper presents the first comprehensive morphometry analysis of normal thyroid, adenomas, and follicular and papillary carcinomas. The mean nuclear volume and the mean nuclear surface increased, while the volume densities of rough endoplasmic reticulum and dense bodies decreased from normal thyroid through adenoma...

journal_title：American journal of clinical pathology

authors： Johannessen JV,Sobrinho-Simóes M,Finseth I,Pilström L

更新日期：1983-02-01 00:00:00