Proposed Terminology for Anal Squamous Lesions: Its Application and Interobserver Agreement Among Pathologists in Academic and Community Hospitals.

abstract：OBJECTIVES:Pathogenic free-living amebae (FLAs) cause skin, ocular, and central nervous system (CNS) infections with significant morbidity and mortality. Diagnosis of FLA infections by pathologic examination of tissue sections can be aided using molecular assays. This study investigated the performance characteristics ...

journal_title：American journal of clinical pathology

authors： Norgan AP,Sloan LM,Pritt BS

更新日期：2019-11-04 00:00:00

abstract：:The performances of four instruments for counting platelets were evaluated in a side-by-side study: the Haema-Count MK-4/HC, an electronic impedance instrument that counts platelets in platelet-rich plasma; the Ultra-Flo 100, and the Coulter Counter Model S-Plus, electronic impedance instruments that count platelets i...

journal_title：American journal of clinical pathology

authors： Dalton WT Jr,Bollinger P,Drewinko B

更新日期：1980-08-01 00:00:00

abstract：:Histologic diagnosis of a nonpalpable breast lesion requires the following: (1) mammographically directed excision of the suspect lesion, (2) recovery of the target lesion from the tissue specimen, and (3) demonstration of the lesion in histologic section. Recovery of lesional tissue is a function of localization with...

journal_title：American journal of clinical pathology

authors： Alberhasky MT

更新日期：1989-10-01 00:00:00

abstract：:Immunostaining of cell cycle-related antigens, especially Ki-67, DNA polymerase alpha, and proliferating cell nuclear antigen, has become an important method to assess the proliferative activity of tumors. These three nuclear antigens were studied by immunohistochemical analysis of cytologic smears. These smears were ...

journal_title：American journal of clinical pathology

authors： Sasano H,Miyazaki S,Nishihira T,Sawai T,Nagura H

更新日期：1992-08-01 00:00:00

abstract：:Multiparameter flow cytometry with optimally selected antibody combinations has expanded the use of this technique beyond traditional applications in hematopathology. By analyzing qualitative patterns of antigen expression on discrete populations or "clusters," one can detect immunophenotypic aberrancy in specific cel...

journal_title：American journal of clinical pathology

authors： Kroft SH

更新日期：2004-12-01 00:00:00

abstract：:We developed anecdotal evidence that parenteral iron therapy is associated with a characteristic pattern of iron staining in bone marrow aspirate smears. In this pattern, uniform blue granules are observed within reticuloendothelial cells/stromal cells with Prussian blue staining, many times in curvilinear arrays. To ...

journal_title：American journal of clinical pathology

authors： Thomason RW,Lavelle J,Nelson D,Lin K,Uherova P

更新日期：2007-10-01 00:00:00

abstract：:To assess the diagnostic accuracy of margin evaluation of melanocytic lesions using en face frozen sections compared with standard paraffin-embedded sections, we studied 2 sets of lesions in which en face frozen sections were used for analysis of surgical margins (13 from malignant melanomas [MMs] and 10 from nonmelan...

journal_title：American journal of clinical pathology

authors： Prieto VG,Argenyi ZB,Barnhill RL,Duray PH,Elenitsas R,From L,Guitart J,Horenstein MG,Ming ME,Piepkorn MW,Rabkin MS,Reed JA,Selim MA,Trotter MJ,Johnson MM,Shea CR

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVES:To characterize error rates for genetic test orders between medical specialties and in different settings by examining detailed order information. METHODS:We performed a retrospective analysis of a detailed utilization management case database, comprising 2.5 years of data and almost 1,400 genetic test orde...

journal_title：American journal of clinical pathology

authors： Mathias PC,Conta JH,Konnick EQ,Sternen DL,Stasi SM,Cole BL,Astion ML,Dickerson JA

更新日期：2016-08-01 00:00:00

abstract：:The effectiveness of fine-needle aspiration (FNA) increases with the number of needle passes, but needle passes are also associated with increased risk of adverse events. The trade-off between needle passes and adequacy has not been well characterized. Clinical studies are limited because of their inherent variability...

journal_title：American journal of clinical pathology

authors： Schmidt RL,Kordy MA,Howard K,Layfield LJ,Hall BJ,Adler DG

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVES:To evaluate the predictive value of growth patterns in patients undergoing sorafenib treatment for metastatic clear cell renal cell carcinomas (CCRCCs). METHODS:Forty-eight patients were analyzed, each of whom underwent nephrectomy and received sorafenib treatment for metastatic CCRCC. Progression-free surv...

journal_title：American journal of clinical pathology

authors： Araki H,Tsuzuki T,Kimura T,Tanaka K,Yamada S,Sassa N,Yoshino Y,Hattori R,Gotoh M

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVES:Universal screening of upper tract urothelial carcinoma (UTUC) for Lynch syndrome by mismatch repair (MMR) protein immunohistochemistry (IHC) has been recommended by some investigators. Herein, we assess this recommendation retrospectively by simulating its performance on a retrospective, unselected cohort o...

journal_title：American journal of clinical pathology

authors： Gayhart MG,Johnson N,Paul A,Quillin JM,Hampton LJ,Idowu MO,Smith SC

更新日期：2020-11-04 00:00:00

abstract：:Prostate-specific antigen (PSA) is a sensitive and specific serum marker for monitoring disease activity in men with prostatic carcinoma. Despite reports of elevation of levels of this analyte in men with benign prostatic hyperplasia, no information is available correlating the serum levels with the actual prostatic a...

journal_title：American journal of clinical pathology

authors： Brawer MK,Rennels MA,Nagle RB,Schifman R,Gaines JA

更新日期：1989-12-01 00:00:00

abstract：:The immunochemical characterization of the light chains of the mesangial immunoglobulin A (IgA) deposits were studied in 45 patients with IgA nephropathy. Kappa and lambda light chains were detected with direct immunofluorescence (IF) method, using monospecific rabbit anti-human anti-kappa and anti-lambda anti-sera. T...

journal_title：American journal of clinical pathology

authors： Lai KN,Chan KW,Mac-Moune F,Ho CP,Yan KW,Lam CW,Vallance-Owen J

更新日期：1986-05-01 00:00:00

abstract：:Mean nuclear areas (MNA) were calculated morphometrically in ten cases of well-differentiated adenocarcinoma, ten cases of atypical alveolar cuboidal cell hyperplasia (AAH), and five cases of alveolar cuboidal cell hyperplasia (AH) and were compared with each other. In cases of adenocarcinoma, the MNA were significant...

journal_title：American journal of clinical pathology

authors： Kodama T,Biyajima S,Watanabe S,Shimosato Y

更新日期：1986-02-01 00:00:00

abstract：:Eight cases are reported of an unusual breast lesion consisting of dense intralobular, perilobular, and perivascular lymphocytic infiltrates associated with lobular atrophy and sclerosis. Immunologic studies on paraffin-embedded tissue (seven cases) and frozen tissue (two cases) demonstrated a predominance of B-cells ...

journal_title：American journal of clinical pathology

authors： Schwartz IS,Strauchen JA

更新日期：1990-06-01 00:00:00

abstract：:Analysis of the data for the 1969 to 1973 CAP Surveys of proficiency in partial thromboplastin time (PTT) determination indicates more than desirable variability in this measurement. Non-activated procedures show greater interlaboratory variability than activated methods; therefore, they may be preferable for routine ...

journal_title：American journal of clinical pathology

authors： Koepke JA

更新日期：1975-06-01 00:00:00

abstract：:Immunophenotypic analysis is useful in distinguishing reactive from neoplastic lymphoproliferations, particularly when tissue is limited or histologic findings are equivocal. Surface membrane immunoglobulin (SmIg) light chain restriction in B cells is especially helpful in documenting clonality, and the loss of SmIg b...

journal_title：American journal of clinical pathology

authors： Zhao XF,Cherian S,Sargent R,Seethala R,Bonner H,Greenberg B,Bagg A

更新日期：2005-07-01 00:00:00

abstract：:A structure resembling a sulfur granule found in histologic sections of endometrium from patients with intrauterine contraceptive devices is described. It is distinguished from a true sulfur granule on morphologic grounds and is further characterized as a foreign substance, most probably fragments of the synthetic con...

journal_title：American journal of clinical pathology

authors： O'Brien PK,Roth-Moyo LA,Davis BA

更新日期：1981-06-01 00:00:00

abstract：:Noncardiogenic pulmonary edema caused by transfusion has been observed for almost 60 years. Today, we know this entity as transfusion-related acute lung injury (TRALI). TRALI is an uncommon but potentially fatal adverse reaction to transfusion of plasma-containing blood components. It is typified by dyspnea, cough, hy...

journal_title：American journal of clinical pathology

authors： Cherry T,Steciuk M,Reddy VV,Marques MB

更新日期：2008-02-01 00:00:00

abstract：:By studying more than 1,200 patients with cutaneous melanoma and long-term follow-up, I examined the relationship between solar elastosis and age at diagnosis of melanoma, key features of melanoma, and the outcome of overall survival in melanoma. I found that melanomas with elastosis were diagnosed significantly later...

journal_title：American journal of clinical pathology

authors： Vollmer RT

更新日期：2007-08-01 00:00:00

abstract：:Dialogue regarding the autopsy has been sustained largely by medical students and professionals, and by families of deceased patients. Exclusion of the general public may represent a significant reason for the inexorable decline of autopsy rates and politicoeconomic support. Sensitivity to public concerns regarding th...

journal_title：American journal of clinical pathology

authors： McManus BM,Wood SM

更新日期：1996-10-01 00:00:00

abstract：:Two commercial enzyme-linked immunosorbent assays (ELISA) for detection of herpes simplex virus (HSV) antigen in direct clinical specimens were compared with cell culture in primary rabbit kidney and MRC-5. With a total of 238 specimens, the sensitivity and specificity of the Dako ELISA method were determined to be 70...

journal_title：American journal of clinical pathology

authors： Warford AL,Levy RA,Strong CA,Rekrut KA

更新日期：1986-02-01 00:00:00

abstract：:Forty-three laboratories participated in an interlaboratory testing program offered by the College of American Pathologists for the radioimmunoassay (RIA) of carcinoembryonic antigen (CEA). Thirty correctly reported a sample with 1.9 ng of endogenous CEA per ml as less than 2.5 ng. For samples with added exogenous CEA...

journal_title：American journal of clinical pathology

authors： Reynoso G,Keane M,Konopka S

更新日期：1977-07-01 00:00:00

abstract：:The DNA of Borrelia burgdorferi spirochetes extracted by ammonium hydroxide was used as the template for nested polymerase chain reaction (PCR) amplification of the species-specific 16S ribosomal DNA (rDNA). The primers were those well known to be specific for signature sequence amplification of the B burgdorferi sens...

journal_title：American journal of clinical pathology

authors： Lee SH,Vigliotti VS,Vigliotti JS,Jones W,Pappu S

更新日期：2010-04-01 00:00:00

abstract：:Results of a comparison of the diagnostic efficacy of percutaneous needle biopsy of the parietal pleura with that of cytologic examination of pleural fluid sediment obtained concurrently from 166 patients with benign or cancerous pleural disorders are reported. Of 44 patients with confirmatory evidence of cancer invol...

journal_title：American journal of clinical pathology

authors： Frist B,Kahan AV,Koss LG

更新日期：1979-07-01 00:00:00

abstract：:We compared the grading and staging of transurethral resection of the bladder (TURB) and cystectomy specimens for 105 patients who underwent radical cystectomy for urothelial carcinoma between 1980 and 1984. Of 105 patients, 96% underwent cystectomy within 100 days of TURB (median interval, 10 days). Grading was perfo...

journal_title：American journal of clinical pathology

authors： Cheng L,Neumann RM,Weaver AL,Cheville JC,Leibovich BC,Ramnani DM,Scherer BG,Nehra A,Zincke H,Bostwick DG

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVES:Tissue confirmation of the intrauterine location of a pregnancy can be difficult grossly, necessitating a frozen section diagnosis. First-trimester tissue is often scant and can be exhausted by frozen section. We examined 39 endometrial curettings performed for rule-out ectopic pregnancy by touch prep to exa...

journal_title：American journal of clinical pathology

authors： Chen AL,Tambouret RH,Roberts DJ

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVES:Pool testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) preserves testing resources at the risk of missing specimens through specimen dilution. METHODS:To determine whether SARS-CoV-2 specimens would be missed after 10:1 pooling, we identified 10 specimens with midrange (ie, 25-34 cycl...

journal_title：American journal of clinical pathology

authors： Procop GW,Tuohy M,Ramsey C,Rhoads DD,Rubin BP,Figler R

更新日期：2021-01-05 00:00:00

abstract：:Platelet function testing is important for the diagnostic evaluation of common and rare bleeding disorders. Our study goals were to promote best practices and reduce unnecessary testing variances by developing North American guidelines on platelet function testing. Guidelines were developed by consensus for expert rec...

journal_title：American journal of clinical pathology

authors： Hayward CP,Moffat KA,Raby A,Israels S,Plumhoff E,Flynn G,Zehnder JL

更新日期：2010-12-01 00:00:00

abstract：:The purpose of this study was to examine a system of quality assurance in which microscopic slides from all surgical cases were subject to peer review before completion of the final pathology report. Three thousand surgical pathology cases were evaluated and the diagnoses entered on preliminary diagnosis sheets. Micro...

journal_title：American journal of clinical pathology

authors： Whitehead ME,Fitzwater JE,Lindley SK,Kern SB,Ulirsch RC,Winecoff WF 3rd

更新日期：1984-04-01 00:00:00