The autopsy. Simple thoughts about the public needs and how to address them.

abstract：:Seven monoclonal antibodies of rat origin were generated against human epidermal keratins and were assayed by immunoblot and by immunoperoxidase staining of frozen sections from various human epithelial tissues. By immunoblotting, the antibodies recognized two different subsets of high molecular weight cytokeratin pol...

journal_title：American journal of clinical pathology

authors： Chin NW,Lai BT,Lanks KW

更新日期：1988-03-01 00:00:00

abstract：OBJECTIVES:To investigate the clinicopathologic features of extranodal natural killer/T-cell lymphoma (ENKTL) not preceded by another Epstein-Barr virus (EBV)-related disorder in children and adolescents. METHODS:A series of 17 cases of ENKTL not preceded by another EBV-related disorder in children and adolescents in ...

journal_title：American journal of clinical pathology

authors： Huang Y,Xie J,Ding Y,Zhou X

更新日期：2016-01-01 00:00:00

abstract：:The authors illustrate two neoplasms arising in the pretibial soft tissue that are histologically identical to adamantinoma of the long bones. The tumors developed in a 24-year-old woman and a 31-year-old man. Both were treated by local excision. Histologically, one tumor had a tubular pattern and one was composed of ...

journal_title：American journal of clinical pathology

authors： Mills SE,Rosai J

更新日期：1985-01-01 00:00:00

abstract：:An American black family in whom hemoglobin J Baltimore and beta (+)-thalassemia genes coexisted is described. The proposita is a 23-year-old woman with a hemoglobin (Hb) level of 11.5 g/dl, microcytic, hypochromic indices, increased values of Hbs A2 and F, and alpha/non-alpha synthetic ratio of 1.52. Hbs A and J Balt...

journal_title：American journal of clinical pathology

authors： Ballas SK,Atwater J,Theriault C,Kim HC,Propst M

更新日期：1981-06-01 00:00:00

abstract：:We aimed to establish whether morphologic parameters were prognostically important in a large series of breast phyllodes tumors in Asian women. Of 335 phyllodes tumors diagnosed at the Department of Pathology, Singapore General Hospital, Singapore, between January 1992 and December 2002, 250 (74.6%) were benign, 54 (1...

journal_title：American journal of clinical pathology

authors： Tan PH,Jayabaskar T,Chuah KL,Lee HY,Tan Y,Hilmy M,Hung H,Selvarajan S,Bay BH

更新日期：2005-04-01 00:00:00

abstract：:In a preliminary attempt to distinguish random intrinsic and methodologic variations of blood lipid levels from any that have possibly been induced by ingestion of vitamin E, blood samples were analyzed in duplicate for lipids several times before and during oral vitamin E administration. Three of eight subjects showe...

journal_title：American journal of clinical pathology

authors： Muckle TJ,Nazir DJ

更新日期：1989-02-01 00:00:00

abstract：:An immunohistochemical study was conducted of 108 papillary carcinoma cases, including 48 cases with intratumoral heterotopic ossification (IHO). In 48 cases, papillary carcinoma with IHO was accompanied by nodular fibrosis. Cases of papillary carcinoma with IHO or nodular fibrosis showed higher incidences of lymph no...

journal_title：American journal of clinical pathology

authors： Takeda M,Mikami T,Numata Y,Okamoto M,Okayasu I

更新日期：2013-05-01 00:00:00

abstract：:Accurate diagnosis of oral hairy leukoplakia (OHL) is important because it may be an early indicator of undiagnosed HIV infection; moreover, it may be a prognostic indicator. Our purpose was to investigate the histopathologic features of subclinical OHL and to evaluate and support the rationale of detecting subclinica...

journal_title：American journal of clinical pathology

authors： Dias EP,Rocha ML,Silva JúniorA,Spyrides KS,Ferreira SM,Polignano GA,Feijó EC,Da Fonseca EC

更新日期：2000-09-01 00:00:00

abstract：:Several adulterants are used to mask tests for abused drugs in urine. Adulterants such as "Klear" and "Whizzies" contain potassium nitrite, and "Urine Luck" contains pyridinium chlorochromate (PCC). The presence of these adulterants cannot be detected by routine specimen integrity checks (pH, specific gravity, and tem...

journal_title：American journal of clinical pathology

authors： Dasgupta A,Wahed A,Wells A

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVES:To determine the public health surveillance severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing volume needed, both for acute infection and seroprevalence. METHODS:Required testing volumes were developed using standard statistical methods based on test analytical performance, disease preval...

journal_title：American journal of clinical pathology

authors： Hilborne LH,Wagner Z,Cabreros I,Brook RH

更新日期：2020-07-07 00:00:00

abstract：:Specific esterase activity, a property generally ascribed to cells of granulocytic origin, was found in abnormal erythroid precursors obtained from the bone marrows of six patients with untreated erythroleukemia. These erythroblasts also showed nonspecific esterase activity. Neither specific nor nonspecific esterase a...

journal_title：American journal of clinical pathology

authors： Kass L

更新日期：1977-04-01 00:00:00

abstract：OBJECTIVES:Pure erythroid leukemia (PEL) is exceptionally rare in the pediatric setting. Four pediatric PEL cases with t(1;16)(p31;q24) NFIA-CBFA2T3 were reported previously. We present a case of an infant with PEL presenting with erythroblastic sarcoma and harboring a novel t(1;8)(p31.3;q21.3) NFIA-RUNX1T1 fusion dete...

journal_title：American journal of clinical pathology

authors： King RL,Siaghani PJ,Wong K,Edlefsen K,Shane L,Howard MT,Reichard KK,Mai M,Viswanatha DS,Greipp PT,Goble TA,Ruiz M,Hara H

更新日期：2020-12-14 00:00:00

abstract：:The authors describe the case of a 33-year-old man with a solitary cystic lesion of the left distal radius with central radiodensities that radiographically suggested a chondroid matrix. Curettage of the lesion revealed numerous calcospherites with a lamellar structure. This lamellar pattern is thought to be a result ...

journal_title：American journal of clinical pathology

authors： Kragel PJ,Williams J,Garvin DF,Goral AB

更新日期：1989-12-01 00:00:00

abstract：:CD163, a hemoglobin scavenger receptor, is expressed in monocytes and macrophages. Recent work has shown that this marker is specific for neoplasms of histiocytic differentiation. Our aim was to test the ability of CD163 to separate cutaneous histiocytomas from their morphologic mimics. We tested the expression of CD1...

journal_title：American journal of clinical pathology

authors： Sachdev R,Robbins J,Kohler S,Vanchinathan V,Schwartz EJ,Sundram UN

更新日期：2010-06-01 00:00:00

abstract：:We evaluated a more efficient method of processing liquid-based cervical cytology specimens for human papillomavirus (HPV) DNA testing by Hybrid Capture II (HCII). Aliquots were made from 701 specimens in the following sequence: 4.0, 2.0, 1.0, 0.5, and 1.5 mL. The 4.0-mL aliquot was processed by the standard method (S...

journal_title：American journal of clinical pathology

authors： Castle PE,Garcia-Meijide M,Holladay EB,Chuke R,Payne J,Long A,Siefers H,Demuth F,Lorincz AT

更新日期：2005-02-01 00:00:00

abstract：:The frequency with which blood gas measurements should be obtained is controversial because laboratory-based blood gas analyzers impose blood loss, delay, and cost on each measurement. Point-of-care analyzers eliminate the delay factor, but blood loss and cost factors remain. Optode microsensing can be adopted readily...

journal_title：American journal of clinical pathology

authors： Shapiro BA

更新日期：1995-10-01 00:00:00

abstract：:Platelet factor 4 (PF4)/heparin antibody, typically associated with heparin therapy, is reported in some heparin-naive people. Seroprevalence in the general population, however, remains unclear. We prospectively evaluated PF4/heparin antibody in approximately 4,000 blood bank donors using a commercial enzyme-linked im...

journal_title：American journal of clinical pathology

authors： Hursting MJ,Pai PJ,McCracken JE,Hwang F,Suvarna S,Lokhnygina Y,Bandarenko N,Arepally GM

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVES:To assess physicians' and nurses' satisfaction with the service provided by the laboratory at Gondar University Hospital. METHODS:We conducted a cross-sectional study involving 196 nurses and physicians. RESULTS:Overall level of satisfaction was 51.1% for nurses and 51.5% for physicians. Lack of consistenc...

journal_title：American journal of clinical pathology

authors： Addis Z,Birhan W,Derseh D,Sahle B,Gizaw N

更新日期：2013-09-01 00:00:00

abstract：:Anaplastic large cell lymphoma (ALCL) is recognized as 2 distinct diseases: anaplastic lymphoma kinase (ALK)+ ALCL and ALK- ALCL. ALK+ ALCL occurs in younger patients and has a better prognosis. Human T-cell lymphotropic virus (HTLV-1) is linked to the development of adult T-cell leukemia/lymphoma (ATLL), which freque...

journal_title：American journal of clinical pathology

authors： Gualco G,Chioato L,Weiss LM,Harrington WJ Jr,Bacchi CE

更新日期：2009-07-01 00:00:00

abstract：:Two unusual cases of acute lymphoblastic leukemia-hand mirror variant (ALL-HMV) are presented. One patient demonstrated a mixed immunophenotype with HLA-DR, My7, transferrin receptor surface markers, and terminal deoxynucleotidyl transferase positivity. To the authors' knowledge, this is the first ALL-HMV reported wit...

journal_title：American journal of clinical pathology

authors： Schumacher HR,Desai SN,McClain KL,Domenico DR,Dizikes GJ,Bird ML

更新日期：1989-04-01 00:00:00

abstract：:Infusible platelet membranes (IPMs) prepared from fresh or outdated human platelets have been shown to correct prolonged bleeding times in thrombocytopenic rabbits. In previous trials, IPMs did not seem to be immunogenic and lacked dose-limiting toxicity. The present study was undertaken to explore whether the platele...

journal_title：American journal of clinical pathology

authors： Graham SS,Gonchoroff NJ,Miller JL

更新日期：2001-01-01 00:00:00

abstract：:Mantle cell lymphoma (MCL) expresses pan-B-cell antigens and is usually CD5+/CD10-/CD23-/FMC7+. In this study, we evaluated 52 patients with confirmed diagnoses of MCL and identified variant immunophenotypes in 21 patients (19/48 classical and 2/4 variant MCLs), including CD5- in 6 (12%) of 52, CD10+ in 4 (8%) of 50, ...

journal_title：American journal of clinical pathology

authors： Gao J,Peterson L,Nelson B,Goolsby C,Chen YH

更新日期：2009-11-01 00:00:00

abstract：:Acute myeloid leukemia (AML) with normal cytogenetics represents approximately 40% to 50% of de novo AML. This heterogeneous AML subgroup constitutes the single largest cytogenetic group with an intermediate prognosis. Previous studies have suggested that the Fms-like tyrosine kinase-3 internal tandem duplication (FLT...

journal_title：American journal of clinical pathology

authors： Rausei-Mills V,Chang KL,Gaal KK,Weiss LM,Huang Q

更新日期：2008-04-01 00:00:00

abstract：:The purpose of our study was to clarify the prognosis of lymphoepithelioma-like carcinoma (LELC) of the lung, which is rare. We analyzed the clinicopathologic features of 32 cases of pulmonary LELC and compared the cases with 84 cases of pulmonary non-LELC with available long-term follow-up information. The results sh...

journal_title：American journal of clinical pathology

authors： Han AJ,Xiong M,Gu YY,Lin SX,Xiong M

更新日期：2001-06-01 00:00:00

abstract：:We investigated the pathologic significance of ductular reactions in chronic liver diseases with respect to cellular senescence. The expression of senescence-associated markers (p16(INK4a) and p21(WAF1/Cip1)), cell proliferation, cell cycle markers (cyclin D and cyclin A), and neural cell adhesion molecule (NCAM) was ...

journal_title：American journal of clinical pathology

authors： Sasaki M,Ikeda H,Yamaguchi J,Miyakoshi M,Sato Y,Nakanuma Y

更新日期：2010-02-01 00:00:00

abstract：Objectives:To evaluate the prevalence of potentially unnecessary repeat testing (PURT) and the associated economic burden for an inpatient population at a large academic medical facility. Methods:We evaluated all inpatient test orders during 2016 for PURT by comparing the intertest times to published recommendations. ...

journal_title：American journal of clinical pathology

authors： Hueth KD,Jackson BR,Schmidt RL

更新日期：2018-05-31 00:00:00

abstract：:Congenital-infantile fibrosarcoma (CIFS) is a relatively indolent sarcoma that should be distinguished from more aggressive spindle cell sarcomas of childhood. CIFSs have been found to have a novel recurrent reciprocal translocation t(12;15)(p13;q25) resulting in the gene fusion ETV6-NTRK3 (ETS variant gene 6; neurotr...

journal_title：American journal of clinical pathology

authors： Sheng WQ,Hisaoka M,Okamoto S,Tanaka A,Meis-Kindblom JM,Kindblom LG,Ishida T,Nojima T,Hashimoto H

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVES:Myeloid and lymphoid neoplasms with abnormalities of fibroblast growth factor receptor 1 gene (FGFR1) are a rare and aggressive disease group that harbors translocations of FGFR1 with at least 14 recognized partner genes. We report a case of a patient with a novel t(17;21)(p13;q22) with RUNX1 rearrangement a...

journal_title：American journal of clinical pathology

authors： Kumar KR,Chen W,Koduru PR,Luu HS

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVES:Human epidermal growth factor receptor 2 (HER2, ERBB2) testing is an important prognostic/predictive marker in breast cancer management, especially in selecting HER2-targeted treatment. American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP) guidelines address HER2 status and were...

journal_title：American journal of clinical pathology

authors： Long TH,Lawce H,Durum C,Moore SR,Olson SB,Gatter K,Troxell ML

更新日期：2015-08-01 00:00:00

abstract：:A rapid, convenient immunologic assay technic for fibrinogen is reported. Basically a latex agglutination, the assay technic, called kinetic latex agglutinometry, quantitates the increase in light transmission that occurs in a stirred suspension of anti-fibrinogen-coated latex beads after the addition of a plasma or w...

journal_title：American journal of clinical pathology

authors： Babson AL,Opper CA,Crane LJ

更新日期：1982-04-01 00:00:00