Quality assurance of histopathologic diagnoses: a prospective audit of three thousand cases.

abstract：:This report describes four siblings affected with familial intrahepatic cholestasis detected in early infancy. In the two male siblings, biliary cirrhosis and fatal hepatocellular carcinoma later developed, whereas the female siblings have had persistent hepatomegaly and recurrent episodes of cholestasis. Sequential b...

journal_title：American journal of clinical pathology

authors： Ugarte N,Gonzalez-Crussi F

更新日期：1981-08-01 00:00:00

abstract：:Free testosterone (FT) measurement by equilibrium dialysis and liquid chromatography-tandem mass spectroscopy (LCMS/MS) is the "gold standard." We hypothesized that calculated FT values could substitute for measured values; compared FT results reported by Walter Reed Army Medical Center (WRAMC), Washington, DC, with r...

journal_title：American journal of clinical pathology

authors： DeVan ML,Bankson DD,Abadie JM

更新日期：2008-03-01 00:00:00

abstract：:Delta checking is a laboratory information system (LIS)-based tool that detects patient and laboratory quality control errors. By using hemoglobin A1c (HbA1c) data, we developed a novel approach to summarizing and presenting patient Delta values to address limitations of current Delta check algorithms. Delta values we...

journal_title：American journal of clinical pathology

authors： Tran DV,Cembrowski GS,Lee T,Higgins TN

更新日期：2008-08-01 00:00:00

abstract：:Plasma biomarker analysis requires intact unbiased starting material. We analyzed the effects on plasma protein profiles of protease inhibitor cocktails and preprocessing storage. Plasma from 12 healthy subjects collected with and without protease inhibitors was prepared immediately and after 2 hours of room temperatu...

journal_title：American journal of clinical pathology

authors： Ayache S,Panelli M,Marincola FM,Stroncek DF

更新日期：2006-08-01 00:00:00

abstract：:Immunoperoxidase strains for prostate-specific antigen (PSA), prostatic acid phosphatase (PAcP), epithelial membrane antigen (EMA), and cytokeratins (MAK 6 and CK-KES) were performed on 1 case of squamous cell carcinoma of the prostate and on 13 cases of squamous metaplasia of prostatic epithelium in an effort to demo...

journal_title：American journal of clinical pathology

authors： Lager DJ,Goeken JA,Kemp JD,Robinson RA

更新日期：1988-11-01 00:00:00

abstract：:Cryostat sections from fully developed papular lesions of lymphomatoid papulosis (histologic subtype A or B) have been examined by immunoenzymatic staining with 24 monoclonal antibodies against lymphoid cells and their subsets. The lesions demonstrated essentially identical cellular compositions and consisted of T-lym...

journal_title：American journal of clinical pathology

authors： Ralfkiaer E,Stein H,Wantzin GL,Thomsen K,Ralfkiaer N,Mason DY

更新日期：1985-11-01 00:00:00

abstract：:Fresh frozen plasma (FFP) normally requires about 45 min to thaw in a 37 degrees C water bath when placed inside an additional plastic overbag. That relatively prolonged time may result in non-utilization or delays in delivery of the product, especially, during emergency surgery. One report recommends the use of a mic...

journal_title：American journal of clinical pathology

authors： Westphal RG,Tindle B,Howard PL,Golden EA,Page GA

更新日期：1982-08-01 00:00:00

abstract：:Remarkable improvements have been made in blood safety since the onset of the HIV epidemic. However, the current paradigm does not prevent all transfusion-transmitted infections and is reactive to new agents, thus accepting that some patients may be harmed before preventive measures are introduced. Several methods are...

journal_title：American journal of clinical pathology

authors： McCullough J

更新日期：2007-12-01 00:00:00

abstract：:Platelet factor 4 (PF4)/heparin antibody, typically associated with heparin therapy, is reported in some heparin-naive people. Seroprevalence in the general population, however, remains unclear. We prospectively evaluated PF4/heparin antibody in approximately 4,000 blood bank donors using a commercial enzyme-linked im...

journal_title：American journal of clinical pathology

authors： Hursting MJ,Pai PJ,McCracken JE,Hwang F,Suvarna S,Lokhnygina Y,Bandarenko N,Arepally GM

更新日期：2010-11-01 00:00:00

abstract：:A 3-year-old girl of Navajo heritage had intractable diarrhea beginning at 4 days of age and resulting in long-term hyperalimentation. Investigation before multivisceral transplantation included biopsies of the rectum, stomach, duodenum, and liver. The diagnosis of microvillus inclusion disease was established by docu...

journal_title：American journal of clinical pathology

authors： Schofield DE,Agostini RM Jr,Yunis EJ

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVES:The objective of this research was to determine test intervals between intraoperator case reviews to minimize the impact of recall. METHODS:Three pathologists were presented with a group of 120 slides and subsequently challenged with a study set of 120 slides after 2-week and 4-week intervals. The challenge...

journal_title：American journal of clinical pathology

authors： Campbell WS,Talmon GA,Foster KW,Baker JJ,Smith LM,Hinrichs SH

更新日期：2015-03-01 00:00:00

abstract：:The ability of the cervical Papanicolaou (Pap) smear to detect cervicitis associated with Chlamydia trachomatis was investigated. Cultures and cervical cytology samples were obtained from 487 women seen at the Mayo Clinic Department of Obstetrics and Gynecology and at the Sexually Transmitted Disease clinic of the Olm...

journal_title：American journal of clinical pathology

authors： Dorman SA,Danos LM,Wilson DJ,Noller KL,Malkasian GD,Goellner JR,Smith TF

更新日期：1983-04-01 00:00:00

abstract：:Platelet refractoriness is caused by HLA antibodies and platelet-specific antibodies. Current methods used to detect antiplatelet antibodies have limitations. Solid phase red cell adherence (SPRCA) lacks sensitivity and requires a second assay using chloroquine-treated intact platelets to specify the response due to a...

journal_title：American journal of clinical pathology

authors： Vongchan P,Nawarawong W,Linhardt RJ

更新日期：2008-09-01 00:00:00

abstract：:Overexpression and amplification of the HER-2 oncogene in patients with breast cancer has correlated with early onset of metastasis, resistance to hormonal therapy and some forms of chemotherapy, and shortened survival. Therefore, evaluation of this putative prognostic or predictive factor seems critical. Because diff...

journal_title：American journal of clinical pathology

authors： Gancberg D,Lespagnard L,Rouas G,Paesmans M,Piccart M,Di Leo A,Nogaret JM,Hertens D,Verhest A,Larsimont D

更新日期：2000-05-01 00:00:00

abstract：:Multicentric osteosarcoma (M-OGS) is characterized by multicentricity of osseous osteosarcomas, either synchronous or metachronous, without visceral involvement. The study's purpose was to clinicopathologically and radiographically analyze 56 cases of M-OGS (22 synchronous and 34 metachronous). The distal femur was th...

journal_title：American journal of clinical pathology

authors： Corradi D,Wenger DE,Bertoni F,Bacchini P,Bosio S,Goldoni M,Unni KK,Sim FH,Inwards CY

更新日期：2011-11-01 00:00:00

abstract：:The probabilities of low transferrin saturation, folic acid, or vitamin B12 levels in association with various erythrocyte indices was determined from the prevalences of these abnormalities and the distributions of the indices among 206 hospitalized and 1,000 ambulatory anemic patients. At mean corpuscular hemoglobin ...

journal_title：American journal of clinical pathology

authors： Griner PF,Oranburg PR

更新日期：1978-11-01 00:00:00

abstract：Objectives:Approximately 15% of breast cancers show equivocal human epidermal growth factor receptor 2 (HER2) results on HER2 immunohistochemistry (IHC) and are reflexed for fluorescence in situ hybridization (FISH). However, some cases remain equivocal. In this study, we evaluated these double-equivocal cases by using...

journal_title：American journal of clinical pathology

authors： Hou Y,Nitta H,Li Z

更新日期：2017-01-01 00:00:00

abstract：:For quality-control purposes, federal regulations require cytology laboratories to compare Papanicolaou smear and cervical biopsy reports, if available, and determine the cause of any discrepancies. The authors reviewed 56,497 cervicovaginal smears, of which 1,582 (2.8%) had a subsequent cervical biopsy or endocervica...

journal_title：American journal of clinical pathology

authors： Joste NE,Crum CP,Cibas ES

更新日期：1995-01-01 00:00:00

abstract：:Adenocarcinomas of the sigmoid colon and rectum were studied for the presence of blood group substances of the A, B, H system using the method of specific erythrocytic adherence. Of 17 adenocarcinomas studied, eight were found to have reactivity for blood group substances. All eight tumours showing reactivity for bloo...

journal_title：American journal of clinical pathology

authors： Cooper HS,Haesler WE Jr

更新日期：1978-06-01 00:00:00

abstract：:Apocrine carcinoma (AC) is an uncommon, poorly characterized type of breast tumor. In this review, 55 patients with intraductal (ID) AC and 17 patients with infiltrating (IF) AC were analyzed retrospectively to define the histologic features and clinical course of this neoplasm. Recurrences in the breast occurred in 3...

journal_title：American journal of clinical pathology

authors： Abati AD,Kimmel M,Rosen PP

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVES:To characterize the clinical and pathologic features of mantle cell lymphoma with mantle zone growth pattern (MCL-MZGP). METHODS:The clinicopathologic data from 35 cases of MCL-MZGP obtained in 12 centers were analyzed. RESULTS:The patients with MCL-MZGP typically sought treatment at high clinical stages (...

journal_title：American journal of clinical pathology

authors： Yuan J,Li S,Liu X,Su RJ,Chen M,Wu X,Zheng G,Smith LM,Wang L,Li Y,Liu C,Zhou J,Shen Q,Zhang L,Wang E,Xu ML,Pan Z

更新日期：2019-07-05 00:00:00

abstract：:Counterimmunoelectrophoresis was used to detect Cryptococcus neoformans capsular polysaccharide in the body fluids of infected patients. Using rabbit anti-C. neoformans A15 globulin, counterimmunoelectrophoresis detected 1.25 microgram of purified cryptococcal polysaccharide per ml of cerebrospinal fluid (CSF) or urin...

journal_title：American journal of clinical pathology

authors： Maccani JE

更新日期：1977-07-01 00:00:00

abstract：:An atypical form of macrocytosis termed volumetric macrocytosis is described. In contrast to the macrocyte associated with megaloblastic anemia and the pseudomacrocyte caused by viscoelastic defects, the volumetric macrocyte is characterized by an increased mean corpuscular volume and a normal cell diameter. The volum...

journal_title：American journal of clinical pathology

authors： Burns ER,Reed LJ,Wenz B

更新日期：1986-03-01 00:00:00

abstract：:Mantle cell lymphoma (MCL) is characterized by typical morphologic features and the CD5+, CD23-immunophenotype. However, some morphologically typical MCLs are CD23+. A t(11;14)(q13;q32) translocation is frequently found in MCL, leading to overexpression of cyclin D1. We studied the expression of cyclin D1 in 50 small ...

journal_title：American journal of clinical pathology

authors： Peghini PE,Fehr J

更新日期：2002-02-01 00:00:00

abstract：:Haemophilus influenzae type b, Escherichia coli, Neisseria meningitis, Streptococcus agalactiae, and Streptococcus pneumoniae are classically the predominant meningeal pathogens of children. The Directigen latex agglutination test identifies these pathogens by detecting specific antigens in cerebrospinal fluid (CSF) a...

journal_title：American journal of clinical pathology

authors： Hill RB,Adams S,Gunn BA,Eberly BJ

更新日期：1994-06-01 00:00:00

abstract：:A markedly prolonged activated partial thromboplastin time (APTT) was observed in a 61-year-old woman with bruising and a decreasing hematocrit. Coagulation laboratory evaluation was sought to determine the cause of the prolonged APTT and bleeding. Evaluation demonstrated that, rather than identifying a coagulopathy, ...

journal_title：American journal of clinical pathology

authors： Humphries JE,Acker MN,Schnell DE,Knarr JW

更新日期：1993-08-01 00:00:00

abstract：:We noticed almost routine disparate results in margin lengths when colorectal specimens are measured in vivo by the surgeon and in vitro by the pathologist. We studied 26 sigmoid and rectum specimens to document the amount of organ shrinkage after surgical removal and fixation. Each specimen had a 5.0-cm segment at ea...

journal_title：American journal of clinical pathology

authors： Goldstein NS,Soman A,Sacksner J

更新日期：1999-03-01 00:00:00

abstract：Objectives:Free light chain (FLC) measurement gained a lot of interest for diagnostic workup of monoclonal gammopathy. Methods:We evaluated the performance of turbidimetric polyclonal Freelite (The Binding Site, Birmingham, UK) assays on Cobas 6000 (Roche Diagnostics, Rotkreuz, Switzerland) and nephelometric monoclona...

journal_title：American journal of clinical pathology

authors： Messiaen AS,De Sloovere MMW,Claus PE,Vercammen M,Van Hoovels L,Heylen O,Debrabandere J,Vanpoucke H,De Smet D

更新日期：2017-06-01 00:00:00

abstract：:A new generation hematology analyzer, Abbott CELL-DYN 4000 (CD 4000), capable of providing 26 parameters, including fully automated reticulocyte, nucleated RBC, blast, band, and immature granulocyte, and variant lymphocyte counts, was evaluated by using the National Committee for Clinical Laboratory Standards H20-A pr...

journal_title：American journal of clinical pathology

authors： Grimaldi E,Scopacasa F

更新日期：2000-04-01 00:00:00

abstract：:Patients with nonhemolytic Lewis antibodies in the serum were transfused on the basis of major crossmatch compatibility alone. No adverse clinical affects were noted when 33 such patients received a total of 230 transfusions. Considerable savings in technologist time and reagent cost were realized by adopting this pol...

journal_title：American journal of clinical pathology

authors： Waheed A,Kennedy MS,Gerhan S,Senhauser DA

更新日期：1981-09-01 00:00:00