Percutaneous ultrasound-guided needle biopsy of hepatic mass lesions using a cytohistologic approach. Comparison of two needle types.

Abstract:

:This study compared the ability to diagnose and accurately classify hepatic mass lesions by ultrasound-guided biopsy using two different needle types: a 20 gauge needle that yielded primarily cytologic material and an 18 gauge automated core biopsy needle. Slides prepared from each of the needle types were separately evaluated in a blinded fashion. The 20 gauge needle had a sensitivity of 90%, a specificity of 90%, and enabled exact tumor classification in 70% of cases. The 18 gauge core biopsy had a sensitivity of 85%, a specificity of 100%, and allowed exact tumor typing in 82% of cases. The sensitivity and specificity of both needle types combined was 98% and 100%, respectively, and all malignancies were correctly typed. A combined cytohistologic approach provides a highly accurate means of diagnosing and typing hepatic tumors and provides a suitable sample for confirmatory stains. Accurate tumor typing may affect therapeutic decisions.

journal_name

Am J Clin Pathol

authors

Dusenbery D,Ferris JV,Thaete FL,Carr BI

doi

10.1093/ajcp/104.5.583

subject

Has Abstract

pub_date

1995-11-01 00:00:00

pages

583-7

issue

5

eissn

0002-9173

issn

1943-7722

journal_volume

104

pub_type

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