Well-differentiated (tubular) carcinoma of the breast. A clinicopathologic study of 145 pure and mixed cases.

abstract：:The cytologic features of fine-needle aspiration specimens from 16 breast carcinomas that closely simulated benign lesions were analyzed and compared to smears from fibroadenomas and fibrocystic change. No combination of features was found that accurately separated all benign and malignant cases. Many nuclei with disc...

journal_title：American journal of clinical pathology

authors： Rogers LA,Lee KR

更新日期：1992-08-01 00:00:00

abstract：:Marfan syndrome is one of the most common connective tissue diseases and may manifest with a range of symptoms and pathologic changes. We present a retrospective series of 5 cases of patients with Marfan syndrome and pulmonary pathology. Patients were young to middle-aged adults with absent or minimal smoking historie...

journal_title：American journal of clinical pathology

authors： Dyhdalo K,Farver C

更新日期：2011-12-01 00:00:00

abstract：:Double immunostaining of tissue sections by monoclonal antibodies has been performed using, in immunofluorescence, combinations of reagents conjugated with different fluorochromes. These were monoclonal antibodies directly labeled with phycoerythrin (a new red fluorochrome) and haptenated monoclonal antibodies detecte...

journal_title：American journal of clinical pathology

authors： Pizzolo G,Chilosi M

更新日期：1984-07-01 00:00:00

abstract：:Terminal deoxynucleotidyl transferase (TdT) is a marker of lymphoblastic disorders. Previously, the technique for determining TdT on smears was by indirect immunofluorescence. An immunoperoxidase procedure for detecting TdT on smears is reported. Results are in a comparable range with the indirect immunofluorescent te...

journal_title：American journal of clinical pathology

authors： Stass SA,Dean L,Peiper SC,Bollum FJ

更新日期：1982-02-01 00:00:00

abstract：:Elevated T-cell leukemia-1 (TCL1) oncoprotein expression might promote human Burkitt lymphoma (BL) because increased TCL1 causes Burkitt-like lymphomas in TCL1 transgenic mice. Epstein-Barr virus (EBV) infection has been implicated as a cause of increased TCL1 expression in multiple BL cell lines, suggesting a critica...

journal_title：American journal of clinical pathology

authors： Teitell MA,Lones MA,Perkins SL,Sanger WG,Cairo MS,Said JW

更新日期：2005-10-01 00:00:00

abstract：:A case of septicemia caused by Pseudomonas paucimobilis is reported. This represents the first definitive case of disease produced by this yellow-pigmented, nonfermentative bacillus. ...

journal_title：American journal of clinical pathology

authors： Slotnick IJ,Hall J,Sacks H

更新日期：1979-11-01 00:00:00

abstract：:Over a four-month period, methanol was found in the blood of 18 patients among 687 sequential emergency room admissions screened for alcohols by gas chromatography. In the patients with positive results, blood ethanol ranged from 6 to 570 mg/dL (1.3-123.7 mmol/L), blood methanol from 2.3 to 4.0 mg/dL (0.72-1.25 mmol/L...

journal_title：American journal of clinical pathology

authors： Wargotz ES,Werner M

更新日期：1987-06-01 00:00:00

abstract：OBJECTIVES:Many nonpathologists and some pathologists consider utilization review essential to laboratory quality improvement, but (1) confusion surrounding the definition of "appropriate" laboratory utilization, (2) the reliance on manual chart review, and (3) a lack of leadership have contributed to its unstandardize...

journal_title：American journal of clinical pathology

authors： Hauser RG,Shirts BH

更新日期：2014-06-01 00:00:00

abstract：:Because T-regulatory cells (Tregs) can harmfully impair HIV-specific responses or beneficially limit immune activation, we compared the number of Tregs in lymph nodes from 48 HIV+ patients and 106 HIV- subjects. By using a microscope counting grid, we found that the mean ± SD number of Tregs in lymph nodes was 3 times...

journal_title：American journal of clinical pathology

authors： Arce J,Levin M,Xie Q,Albanese J,Ratech H

更新日期：2011-07-01 00:00:00

abstract：:Cytokeratin (CK) expression was studied in 22 sinonasal inverted papillomas. Columnar (respiratory) epithelium in inverted papillomas abundantly expressed CK7, CK8, CK18, and CK19. Immunoreactivity for CK5/14 and CK17 was found in basal and parabasal/suprabasal cells. Transitional (cuboidal) and squamous epithelium in...

journal_title：American journal of clinical pathology

authors： Schwerer MJ,Kraft K,Baczako K,Maier H

更新日期：2001-05-01 00:00:00

abstract：:CD163, a hemoglobin scavenger receptor, is expressed in monocytes and macrophages. Recent work has shown that this marker is specific for neoplasms of histiocytic differentiation. Our aim was to test the ability of CD163 to separate cutaneous histiocytomas from their morphologic mimics. We tested the expression of CD1...

journal_title：American journal of clinical pathology

authors： Sachdev R,Robbins J,Kohler S,Vanchinathan V,Schwartz EJ,Sundram UN

更新日期：2010-06-01 00:00:00

abstract：:Using Venn diagrams derived from set theory, a mathematic model is presented that allows triple-label immunophenotypic analysis of cells based upon double-label measurements. Practical applications of this method are illustrated and discussed. Using this model, triple-label data concerning Leu-8 and Leu-9 (CD7) antige...

journal_title：American journal of clinical pathology

authors： Wood GS

更新日期：1989-07-01 00:00:00

abstract：:Results of a comparison of the diagnostic efficacy of percutaneous needle biopsy of the parietal pleura with that of cytologic examination of pleural fluid sediment obtained concurrently from 166 patients with benign or cancerous pleural disorders are reported. Of 44 patients with confirmatory evidence of cancer invol...

journal_title：American journal of clinical pathology

authors： Frist B,Kahan AV,Koss LG

更新日期：1979-07-01 00:00:00

abstract：OBJECTIVES:To support our Lean culture of continuous improvement, we implemented a daily management system designed so critical metrics of operational success were the focus of local teams to drive improvements. METHODS:We innovated a standardized visual daily management board composed of metric categories of Quality,...

journal_title：American journal of clinical pathology

authors： Zarbo RJ,Varney RC,Copeland JR,D'Angelo R,Sharma G

更新日期：2015-07-01 00:00:00

abstract：:We examined the occurrence of JAK2(V617F) and JAK2 exon 12 mutations in a clinical cohort of polycythemia vera (PV) in Taiwan. Of 22 patients with PV, 17 (77%) had the V617F mutation, and all 5 V617F-negative patients (23%) had the exon 12 mutation. We found 3 different exon 12 mutations: 3 N542-E543del, 1 F537-K539de...

journal_title：American journal of clinical pathology

authors： Yeh YM,Chen YL,Cheng HY,Su WC,Chow NH,Chen TY,Ho CL

更新日期：2010-08-01 00:00:00

abstract：:Possible increased activation of the coagulation pathway was measured in a group of patients with neoplastic diseases. In addition to standard tests, the thromboplastin generation test, thrombin generation test and immunologic and coagulant activities of both Factor VIII and antithrombin III were utilized in the evalu...

journal_title：American journal of clinical pathology

authors： Losito R,Beaudry P,Valderrama JC,Cousineau L,Longpré B

更新日期：1977-08-01 00:00:00

abstract：:A two-sample plot is often used to display test results in clinical chemistry external quality control programs. The use of control materials at different concentrations calls for a re-evaluation of the two-sample plot. A modification of the two-sample plot is presented. The axes of the graph are graduated in units of...

journal_title：American journal of clinical pathology

authors： Elion-Gerritzen WE

更新日期：1977-01-01 00:00:00

abstract：:The cell cycle consists of an initial growth phase (G1), DNA replication (S), a gap phase (G2), and mitosis (M), after which the cell may differentiate or enter the resting state (G0). The cycle is driven by a number of positive and negative regulatory phosphorylation and dephosphorylation events, involving protein ki...

journal_title：American journal of clinical pathology

authors： Dictor M,Ehinger M,Mertens F,Akervall J,Wennerberg J

更新日期：1999-07-01 00:00:00

abstract：:In 10 cases of Barrett adenocarcinoma, samples from 8 tumor areas (including superficial and deep from peripheral and central areas) and a regional lymph node metastasis were studied for amplification of c-myc, c-erbB-2, and EGFR. We analyzed loss of heterozygosity (LOH) at 3 loci (APC, MCC, and RB) and 2 anonymous mi...

journal_title：American journal of clinical pathology

authors： Owonikoko T,Rees M,Gabbert HE,Sarbia M

更新日期：2002-04-01 00:00:00

abstract：Objectives:The aims were to evaluate breast cancer (BC) tumor-infiltrating lymphocytes (TILs) interobserver variability, heterogeneity, and the fidelity of scoring TILs in core needle biopsy (CNB). Methods:Matching CNB and two full-face sections (FFSs) of BC cases (n = 100) were independently reviewed by two pathologi...

journal_title：American journal of clinical pathology

authors： Khoury T,Peng X,Yan L,Wang D,Nagrale V

更新日期：2018-10-01 00:00:00

abstract：:Same-day turnaround of pathology specimens is desirable in this era of managed care, and rapid microwave tissue processing produces histologic features of a quality equivalent to overnight processing. We studied whether microwave-assisted rapid tissue processing adversely affects the quality of immunohistochemical sta...

journal_title：American journal of clinical pathology

authors： Emerson LL,Tripp SR,Baird BC,Layfield LJ,Rohr LR

更新日期：2006-02-01 00:00:00

abstract：:Several authors have suggested that a plausible mechanism for variation in reported mean corpuscular volume (MCV) and hematocrit values for Hematology Survey Specimens may be due to the presence of hyperglycemia in the suspending matrix of the specimens, resulting in cell swelling due to an osmotic matrix effect. The ...

journal_title：American journal of clinical pathology

authors： Savage RA

更新日期：1983-10-01 00:00:00

abstract：:To investigate the issue of clonality in Richter's syndrome, phenotypic, molecular genetic, and cytogenetic studies were performed on tumor tissue from a patient with concurrent chronic lymphocytic leukemia and diffuse large cell lymphoma in a single lymph node specimen. The tumor was biphenotypic for immunoglobulin (...

journal_title：American journal of clinical pathology

authors： Nakamine H,Masih AS,Sanger WG,Wickert RS,Mitchell DW,Armitage JO,Weisenburger DD

更新日期：1992-05-01 00:00:00

abstract：:The relationship between immunohistochemically measured membranous expression of erbB-2 oncoprotein and prognosis in breast cancer is controversial, and the relationship between cytoplasmic positivity and prognosis has been minimally investigated. The clinical course of 300 women with infiltrating breast carcinoma, wh...

journal_title：American journal of clinical pathology

authors： Keshgegian AA,Cnaan A

更新日期：1997-10-01 00:00:00

abstract：OBJECTIVES:To describe the histopathologic and immunophenotypic features of a temporary splenic allograft exposed to massive donor-specific antibody (DSA) insult. METHODS:A human cadaveric donor splenic allograft was temporarily transplanted in a highly sensitized patient with the intention of removing DSA before inte...

journal_title：American journal of clinical pathology

authors： Gaitonde S,Hassan M,Mehta V,Benedetti E,Tzvetanov I,Lichvar A,Pirzada S,Setty S

更新日期：2020-11-21 00:00:00

abstract：OBJECTIVES:Increased frequency of hyperamylasemia has previously been reported in human immunodeficiency virus (HIV)-positive patients, but studies determined total amylase activity and were performed before the introduction of highly active antiretroviral therapy (HAART). We evaluated the frequency of pancreatic hyper...

journal_title：American journal of clinical pathology

authors： Szőke D,Ridolfo A,Valente C,Galli M,Panteghini M

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:Lymphoid enhancer binding factor 1 (LEF1) is expressed in most cases of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and has shown utility in distinguishing CLL/SLL from other small B-cell lymphomas. LEF1 expression has not been systematically studied in CD5-positive marginal zone lympho...

journal_title：American journal of clinical pathology

authors： Patel N,Durkin L,Bodo J,Hsi ED

更新日期：2020-04-15 00:00:00

abstract：:The present report is that of a civilian episode of fatal, fulminant group Y meningococcemia in a previously healthy adolescent, who denied prior vaccination against group C meningococcus. The patient suffered abrupt onset of purpura, hypotension and cardiopulmonary arrest. A detailed clinical and pathologic report is...

journal_title：American journal of clinical pathology

authors： Bernad PG,Snyder DA,Levey M

更新日期：1977-08-01 00:00:00

abstract：:The authors investigated assays for free protein S (ProS) antigen, total ProS antigen, and ProS crossed immunoelectrophoresis (CIEP) in the diagnosis of type 1 inherited ProS deficiency. Accurate measurement of the hemostatically important free ProS required showing that, on each specimen, precipitation of the C4b-bin...

journal_title：American journal of clinical pathology

authors： Edson JR,Vogt JM,Huesman DA

更新日期：1990-08-01 00:00:00

abstract：:Bleeding problems are symptomatic of platelet delta-storage pool diseases (SPDs) such as Hermansky-Pudlak syndrome. Although at present no cure is available for delta-SPD, early diagnosis is of great importance for prophylactic and supportive treatment. This study tested the usefulness of a flow cytometric assay for p...

journal_title：American journal of clinical pathology

authors： Maurer-Spurej E,Pittendreigh C,Wu JK

更新日期：2007-04-01 00:00:00