Breast carcinoma simulating fibroadenoma or fibrocystic change by fine-needle aspiration. A study of 16 cases.

abstract：OBJECTIVES:To examine carbonic anhydrase IX (CAIX), a marker of renal cell carcinoma that recently has been described in malignant effusions. METHODS:Pleural and peritoneal fluids with the following diagnoses-reactive (n = 23), carcinoma (n = 17), and "suspicious for mesothelioma" (n = 4)-were immunostained for CAIX, ...

journal_title：American journal of clinical pathology

authors： Ananthanarayanan V,Tretiakova M,Husain AN,Krausz T,Antic T

更新日期：2014-07-01 00:00:00

abstract：:The reactivity of eight preferential B-cell (L26, 4KB5, and KiB3) and T-cell (polyclonal CD3, Leu22, MT-1, UCHL-1, and OPD4) antibodies which detect paraffin-resistant antigens was examined by a three-step immunoperoxidase technique in 111 formalin-fixed, paraffin-embedded diffuse aggressive non-Hodgkin's lymphomas (N...

journal_title：American journal of clinical pathology

authors： Chadburn A,Knowles DM

更新日期：1994-09-01 00:00:00

abstract：:The Department of Laboratory Medicine, University of Washington, has explored various management of organizational approaches over the past seven years. The Centralized Processing Area supported by a computerized information system has evolved from these efforts. Despite a decrease in U.W. hospital usage since 1968-69...

journal_title：American journal of clinical pathology

authors： Nussbaum B,Minckler T,Roby R,Ackerman E

更新日期：1977-02-01 00:00:00

abstract：:A practical acidimetric assay for penicillinase production using penicillin and phenol red impregnated in paper discs was developed. Blank discs were first impregnated with buffered penicillin G and, after drying, with 1% phenol red. For use, a disc was added to a bacterial suspension made in saline solution. A yellow...

journal_title：American journal of clinical pathology

authors： Tu KK,Jorgensen JH,Stratton CW

更新日期：1981-04-01 00:00:00

abstract：:The levels of thymus-derived lymphocytes (T-cells) in samples of peripheral blood from 47 patients with carcinoma of the breast, 36 patients with benign mammary lesions, and 33 matched normal controls were determined. Results were analyzed with three statistical tests. It was found that the mean percentages of T-lymph...

journal_title：American journal of clinical pathology

authors： Keller SE,Ioachim HL,Pearse T,Siletti DM

更新日期：1976-04-01 00:00:00

abstract：:The performance characteristics of the XE-2100 (Sysmex, Kobe, Japan) automated immature granulocyte (IG) count were studied. The automated IG count was compared with the manual morphology count and with a proposed reference flow cytometric count. The comparison data were analyzed by both least-squares and Passing-Babl...

journal_title：American journal of clinical pathology

authors： Fernandes B,Hamaguchi Y

更新日期：2007-09-01 00:00:00

abstract：:We developed anecdotal evidence that parenteral iron therapy is associated with a characteristic pattern of iron staining in bone marrow aspirate smears. In this pattern, uniform blue granules are observed within reticuloendothelial cells/stromal cells with Prussian blue staining, many times in curvilinear arrays. To ...

journal_title：American journal of clinical pathology

authors： Thomason RW,Lavelle J,Nelson D,Lin K,Uherova P

更新日期：2007-10-01 00:00:00

abstract：:With the new screening and treatment guidelines and the prospect of human papillomavirus vaccination for adolescents, the current total volume of Papanicolaou (Pap) tests will be significantly reduced. We used available data to assess the current supply and demand in the cytotechnology labor market and how an expected...

journal_title：American journal of clinical pathology

authors： Eltoum IA,Roberson J

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVES:Timely reporting of immunosuppressant (ISP) drug level results is needed for transplant patient management. This study characterized the local ISP testing process, identified bottlenecks and implemented process improvements to meet turnaround time requirements. METHODS:Laboratory information time stamps, di...

journal_title：American journal of clinical pathology

authors： Barakauskas VE,Bradshaw TA,Smith LD,Lehman CM,Johnson-Davis KL

更新日期：2016-08-01 00:00:00

abstract：:A 49-year-old diabetic woman developed polymicrobial anaerobic meningitis secondary to a meningorectal fistula one year after receiving neutron beam therapy for a rectal adenocarcinoma. The meningitis was refractory to chloramphenicol and penicillin but responded to oral metronidazole. Sustained eradication of meningi...

journal_title：American journal of clinical pathology

authors： Walsh TJ,Weinstein RA,Malinoff H,Breyer MD,Berelowitz BA

更新日期：1982-07-01 00:00:00

abstract：:Colorectal cancer with microsatellite instability (MSI) may occur sporadically or be inherited in cases of hereditary nonpolyposis colorectal cancer (HNPCC) syndrome. However, there is no consensus as to which patients must be tested and how to test MSI. In this study, MSI was tested by immunohistochemical analysis an...

journal_title：American journal of clinical pathology

authors： Bouzourene H,Taminelli L,Chaubert P,Monnerat C,Seelentag W,Sandmeier D,Andrejevic S,Matter M,Bosman F,Benhattar J

更新日期：2006-06-01 00:00:00

abstract：:An unusual case of carcinoma of the prostate with metastases is described. the prostate and the metastases showed adenocarcinoma with carcinoid-like areas. A tumor with the same histologic features was found at the tip of the appendix and proved to be metastatic. The possibility of primary carcinoid of the prostate wa...

journal_title：American journal of clinical pathology

authors： Ansari MA,Pintozzi RL,Choi YS,Ladove RF

更新日期：1981-07-01 00:00:00

abstract：:To our knowledge, there are no universally accepted, evidence-based guidelines for how to resolve the HER2 status of tumors demonstrating equivocal amplification. The present study was based on 17 breast core biopsy specimens demonstrating invasive carcinoma with equivocal HER2 amplification, defined as an HER2/chromo...

journal_title：American journal of clinical pathology

authors： Striebel JM,Bhargava R,Horbinski C,Surti U,Dabbs DJ

更新日期：2008-03-01 00:00:00

abstract：:Proper collection, handling, and storage of the blood alcohol specimen are essential in medicolegal cases involving the question of sobriety. A standard operating procedure is necessary to ensure maximum reliability. Comments are offered on the advantages of using blood specimens in preference to urine or tissue speci...

journal_title：American journal of clinical pathology

authors： Kaye S

更新日期：1980-11-01 00:00:00

abstract：:Analysis of the data for the 1969 to 1973 CAP Surveys of proficiency in partial thromboplastin time (PTT) determination indicates more than desirable variability in this measurement. Non-activated procedures show greater interlaboratory variability than activated methods; therefore, they may be preferable for routine ...

journal_title：American journal of clinical pathology

authors： Koepke JA

更新日期：1975-06-01 00:00:00

abstract：:Little information has been reported describing antigen stability in plasma cell myeloma. In this study, the expression frequency and stability of 2 potential therapeutic targets, CD20 and CD52, along with the frequently aberrantly expressed CD56 antigen, were evaluated by flow cytometric analyses in 56 patients with ...

journal_title：American journal of clinical pathology

authors： Cao W,Goolsby CL,Nelson BP,Singhal S,Mehta J,Peterson LC

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:To identify, describe, and investigate the clinical, radiologic, and pathologic features of 8 cases of telangiectatic oncocytoma. METHODS:Fifty-three consecutive renal oncocytomas were reviewed for the telangiectatic pathologic features that were subsequently correlated with the demographic, clinical, and r...

journal_title：American journal of clinical pathology

authors： Xiao GQ,Ko HB,Unger P

更新日期：2013-07-01 00:00:00

abstract：:Elevated T-cell leukemia-1 (TCL1) oncoprotein expression might promote human Burkitt lymphoma (BL) because increased TCL1 causes Burkitt-like lymphomas in TCL1 transgenic mice. Epstein-Barr virus (EBV) infection has been implicated as a cause of increased TCL1 expression in multiple BL cell lines, suggesting a critica...

journal_title：American journal of clinical pathology

authors： Teitell MA,Lones MA,Perkins SL,Sanger WG,Cairo MS,Said JW

更新日期：2005-10-01 00:00:00

abstract：:We compared an automated quantitative heart-type fatty acid-binding protein (H-FABP) assay with other cardiac-marker assays to examine its usefulness as an early diagnostic marker of acute myocardial infarction (AMI). Serum samples for cardiac troponin T (cTnT), creatine kinase-MB isozyme (CK-MB), myoglobin, and H-FAB...

journal_title：American journal of clinical pathology

authors： Kim Y,Kim H,Kim SY,Lee HK,Kwon HJ,Kim YG,Lee J,Kim HM,So BH

更新日期：2010-07-01 00:00:00

abstract：:In the thymus, the relationship between lymphofollicular hyperplasia and mucosa-associated lymphoid tissue (MALT)-type lymphoma is uncertain. We analyzed 14 cases with a diagnosis of thymic follicular hyperplasia in patients with connective tissue disease (n = 2), myasthenia gravis (n = 11), or both (n = 1). In 11 cas...

journal_title：American journal of clinical pathology

authors： Parrens M,Dubus P,Danjoux M,Jougon J,Brousset P,Velly JF,de Mascarel A,Merlio JP

更新日期：2002-01-01 00:00:00

abstract：:This report describes the use of counterimmunoelectrophoresis (CIE) as a method of detecting activation of the complement system. With this technic small amounts of C3 split products (C3c/d) can be detected in plasma samples by specific precipitation with antiserum in less than two hours. The CIE technic is a highly s...

journal_title：American journal of clinical pathology

authors： Arroyave CM,Taylor DG,Gallup P,Nakamura RM

更新日期：1978-04-01 00:00:00

abstract：:The availability of automated anti-Xa heparin assays provides the opportunity to manage patient unfractionated heparin levels directly, rather than by the activated partial thromboplastin time. Because critically ill patients can acquire an antithrombin deficiency, we compared the performance of 3 anti-Xa heparin assa...

journal_title：American journal of clinical pathology

authors： Lehman CM,Rettmann JA,Wilson LW,Markewitz BA

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVES:To compare next-generation sequencing (NGS) platforms with mutation-specific analysis platforms in a clinical setting, in terms of sensitivity, mutation specificity, costs, capacity, and ease of use. METHODS:We analyzed 25 formalin-fixed, paraffin-embedded lung cancer samples of different size and tumor per...

journal_title：American journal of clinical pathology

authors： Hinrichs JW,van Blokland WT,Moons MJ,Radersma RD,Radersma-van Loon JH,de Voijs CM,Rappel SB,Koudijs MJ,Besselink NJ,Willems SM,de Weger RA

更新日期：2015-04-01 00:00:00

abstract：:Measuring HER-2 is important for selecting optimal therapy and predicting prognosis in breast cancer patients. Current methods for evaluating HER-2 include measuring protein overexpression by immunohistochemistry (IHC), measuring gene copy number by fluorescent in situ hybridization (FISH), and measuring shed antigen ...

journal_title：American journal of clinical pathology

authors： Yeh IT

更新日期：2002-06-01 00:00:00

abstract：:Following normalization of blood glucose levels, a marked change in the MCV and in the calculated hematocrit was observed in five patients with transient severe hyperglycemia. The addition of varied concentrations of glucose to blood samples from healthy volunteers and from patients with microcytic, macrocytic, and no...

journal_title：American journal of clinical pathology

authors： Holt JT,DeWandler MJ,Arvan DA

更新日期：1982-05-01 00:00:00

abstract：Objectives:To determine non-American Society for Clinical Pathology pathology- and laboratory-related Choosing Wisely recommendations that drive effective test utilization in the laboratory. Methods:Data were collected via a two-part web-based survey distributed to a broad sample of pathologists and laboratory profess...

journal_title：American journal of clinical pathology

authors： Waibel E,Garcia E,Kelly M,Soles R,Hilborne L

更新日期：2018-02-17 00:00:00

abstract：:Several authors have suggested that a plausible mechanism for variation in reported mean corpuscular volume (MCV) and hematocrit values for Hematology Survey Specimens may be due to the presence of hyperglycemia in the suspending matrix of the specimens, resulting in cell swelling due to an osmotic matrix effect. The ...

journal_title：American journal of clinical pathology

authors： Savage RA

更新日期：1983-10-01 00:00:00

abstract：:We examined benign and malignant mesothelial tissue samples for the presence of X-linked inhibitor of apoptosis protein (XIAP), a potent constituent of the inhibitor of apoptosis family of caspase inhibitors. We subjected 55 sections (31 malignant mesotheliomas, 2 well-differentiated peritoneal mesotheliomas, 13 pleur...

journal_title：American journal of clinical pathology

authors： Wu M,Sun Y,Li G,Desman G,Wang B,Gil J,Burstein DE

更新日期：2007-11-01 00:00:00

abstract：:Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a benign lesion of the oral mucosa of an unclear pathogenesis. We analyzed the profile of the inflammatory infiltrate in 12 cases of TUGSE by using immunohistochemical analysis and polymerase chain reaction-based repertoire analysis to detect T- and B...

journal_title：American journal of clinical pathology

authors： Hirshberg A,Amariglio N,Akrish S,Yahalom R,Rosenbaum H,Okon E,Kaplan I

更新日期：2006-10-01 00:00:00

abstract：:Primary osteomyelitis in a teen-aged boy that mimicked Ewing's tumor radiologically showed small Gram-negative rods on the original smear. The organism isolated was an obligately anaerobic bacterium, finally identified as Clostridium sphenoides. This finding underlines the need for microbiologic analysis of orthopedic...

journal_title：American journal of clinical pathology

authors： Isenberg HD,Lavine LS,Painter BG,Rubins WH,Berkman JI

更新日期：1975-09-01 00:00:00