B-acute lymphoblastic leukemia/lymphoblastic lymphoma.

abstract：:S-100 protein was detected in a small number of human peripheral T-lymphocytes by a direct immunoperoxidase method with the use of monospecific antibody to S-100 protein. Complemented-mediated lysis using monoclonal antibodies revealed that the S-100+ T-lymphocytes bore OKT3, OKT8, and OKT11 antigens but not OKT4, OKM...

journal_title：American journal of clinical pathology

authors： Takahashi K,Isobe T,Ohtsuki Y,Sonobe H,Yamaguchi H,Akagi T

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVES:B-lymphoblastic leukemia (B-LBL) arising in patients with chronic lymphocytic leukemia (CLL) is exceedingly rare and poorly characterized. METHODS:We describe four patients with CLL and concurrent or subsequent B-LBL diagnosed by morphologic, immunophenotypic, cytogenetic, and molecular analysis and reviewe...

journal_title：American journal of clinical pathology

authors： Chakhachiro Z,Yin CC,Abruzzo LV,Aladily TN,Barron LL,Banks HE,Thomas DA,Keating M,Medeiros LJ,Huh YO

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVES:To determine the current state of pathology resident training in genomic and molecular pathology. METHODS:The Training Residents in Genomics (TRIG) Working Group developed survey and knowledge questions for the 2013 pathology Resident In-Service Examination (RISE). Sixteen demographic questions related to a...

journal_title：American journal of clinical pathology

authors： Haspel RL,Rinder HM,Frank KM,Wagner J,Ali AM,Fisher PB,Parks ER,Training Residents in Genomics (TRIG) Working Group.

更新日期：2014-10-01 00:00:00

abstract：:Serologic testing shows that hepatitis C virus (HCV) may have a role in the pathogenesis of B-cell non-Hodgkin lymphomas (B-cell NHLs). We tried to demonstrate HCV RNA sequences in paraffin-embedded tissue from B-cell NHLs by reverse-transcription double polymerase chain reaction (RT-PCR) and Southern blotting. We stu...

journal_title：American journal of clinical pathology

authors： Karavattathayyil SJ,Kalkeri G,Liu HJ,Gaglio P,Garry RF,Krause JR,Dash S

更新日期：2000-03-01 00:00:00

abstract：:Since the introduction of the triple screen, the emergence of additional analytes found to be associated with trisomy 21 pregnancies has challenged the clinical pathology and obstetric communities to determine which combination provides the best performance characteristics as a screening test. The cost, practicality, ...

journal_title：American journal of clinical pathology

authors： Baliff JP,Mooney RA

更新日期：2003-12-01 00:00:00

abstract：:An automated fluorescent immunoassay system (FIAX) was compared with complement fixation (CF) for measuring antibodies to cytomegalovirus (CMV) and herpes simplex virus (HSV) in clinical specimens. Compared with CF the specificity of FIAX (ability to detect a negative titer) was 95% for CMV and 92% for HSV. The sensit...

journal_title：American journal of clinical pathology

authors： Friedman HM,Tustin NB,Hitchings MM,Plotkin SA

更新日期：1981-09-01 00:00:00

abstract：:Primary gastric non-Hodgkin lymphoma of mucosa-associated lymphoid tissue (MALT-NHL) is strongly related to Helicobacter pylori (H pylori) infection. CagA positive H pylori strains appear to be more aggressive, as reflected by a greater degree of gastric inflammation and higher levels of Il-8 production. Using a polym...

journal_title：American journal of clinical pathology

authors： de Jong D,van der Hulst RW,Pals G,van Dijk WC,van der Ende A,Tytgat GN,Taal BG,Boot H

更新日期：1996-11-01 00:00:00

abstract：:We compared an automated quantitative heart-type fatty acid-binding protein (H-FABP) assay with other cardiac-marker assays to examine its usefulness as an early diagnostic marker of acute myocardial infarction (AMI). Serum samples for cardiac troponin T (cTnT), creatine kinase-MB isozyme (CK-MB), myoglobin, and H-FAB...

journal_title：American journal of clinical pathology

authors： Kim Y,Kim H,Kim SY,Lee HK,Kwon HJ,Kim YG,Lee J,Kim HM,So BH

更新日期：2010-07-01 00:00:00

abstract：:Medicare policies have gradually restricted the scope of pathologist services payable under the rules applicable to physician services. Recent changes applying relative value scales has provided an opportunity for national standardization of pathology codes, and has permitted the introduction of clinical pathology int...

journal_title：American journal of clinical pathology

authors： Raslavicus P

更新日期：1993-04-01 00:00:00

abstract：:The effect of blood transfusion on DNA profiles of an individual is a significant issue in the forensic context. In the present study, the effects of blood transfusion in 5 recipients were studied by performing restriction fragment length polymorphism and polymerase chain reaction HLA-DQA1 and Polymarker (LDLR, GYPA, ...

journal_title：American journal of clinical pathology

authors： Giroti RI,Biswas R,Mukherjee K

更新日期：2002-09-01 00:00:00

abstract：:Colorectal cancer with microsatellite instability (MSI) may occur sporadically or be inherited in cases of hereditary nonpolyposis colorectal cancer (HNPCC) syndrome. However, there is no consensus as to which patients must be tested and how to test MSI. In this study, MSI was tested by immunohistochemical analysis an...

journal_title：American journal of clinical pathology

authors： Bouzourene H,Taminelli L,Chaubert P,Monnerat C,Seelentag W,Sandmeier D,Andrejevic S,Matter M,Bosman F,Benhattar J

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVES:Assess support for the effectiveness of two separate practices, restrictive transfusion strategy and computerized physician order entry/clinical decision support (CPOE/CDS) tools, in decreasing RBC transfusions in adult surgical and nonsurgical patients. METHODS:Following the Centers for Disease Control and...

journal_title：American journal of clinical pathology

authors： Derzon JH,Clarke N,Alford A,Gross I,Shander A,Thurer R

更新日期：2019-10-07 00:00:00

abstract：:The professional activities of anatomic and clinical pathologists involve, to a large extent, management issues. To evaluate the management training received by pathology residents, the authors surveyed pathology residency training programs in the United States. Responses were collected from 138 of 187 programs (73.8%...

journal_title：American journal of clinical pathology

authors： Brugnara C,Fenton T,Winkelman JW

更新日期：1994-05-01 00:00:00

abstract：:To determine the performance and frequency of protein C reagents currently used by clinical laboratories, we analyzed North American Specialized Coagulation Laboratory Association (NASCOLA) protein C proficiency testing data from 6 surveys conducted in 2009 and 2010 (2009-1 to 2009-3 and 2010-1 to 2010-3). Interlabora...

journal_title：American journal of clinical pathology

authors： Baron JM,Johnson SM,Ledford-Kraemer MR,Hayward CP,Meijer P,Van Cott EM

更新日期：2012-06-01 00:00:00

abstract：:The present immunoperoxidase study attempted to localize aldosterone and cortisol in formalin-fixed paraffin-embedded adrenal glands or tumors. Apparently, steroid substances are solubilized during routine tissue processing, and the cytoplasm of adrenal cortical cells is not stained by either antialdosterone or antico...

journal_title：American journal of clinical pathology

authors： Hsu SM,Raine L,Martin HF

更新日期：1981-01-01 00:00:00

abstract：:The international sensitivity index (ISI) calibration of point-of-care-test (POCT) prothrombin time (PT) whole blood monitors is complex, requiring manual PT testing of 60 patients' and 20 healthy subjects' plasma samples. The possibility of reducing these numbers was studied by a Monte Carlo Bootstrap study for 2 POC...

journal_title：American journal of clinical pathology

authors： Poller L,Keown M,Chauhan N,van den Besselaar AM,Tripodi A,Jespersen J,Shiach C

更新日期：2002-06-01 00:00:00

abstract：:A unique case of intramural uterine tumor composed of malignant epithelium and benign smooth muscle, adipose tissue, and cartilage is reported. This tumor, which the authors designated "carcinomesenchymoma," apparently represents an example of a previously unreported variant of mixed müllerian tumor that is composed o...

journal_title：American journal of clinical pathology

authors： Chen KT,Vergon JM

更新日期：1981-05-01 00:00:00

abstract：:Immunophenotypic analysis of acute leukemias is time consuming and often requires flow cytometric analysis. A 1-hour alkaline phosphatase-labeled streptavidin-biotin immunocytochemical procedure was evaluated as an alternative. Seventeen cases of acute leukemia, including 10 acute lymphocytic (ALL) and 7 acute nonlymp...

journal_title：American journal of clinical pathology

authors： Hammer RD,Collins RD,Ebrahimi S,Casey TT

更新日期：1992-06-01 00:00:00

abstract：:The presence of small gas bubbles in devices used to collect blood gas samples is considered. A gas bubble whose relative volume is 0.5 to 1% or more that of the liquid in the collection device is a potential source of significant error. Relationships describing the possible magnitude of this error are derived and sub...

journal_title：American journal of clinical pathology

authors： Mueller RG,Lang GE,Beam JM

更新日期：1976-02-01 00:00:00

abstract：:We analyzed the diagnostic role of claudins in effusion cytology in 325 effusions, including 218 ovarian, 49 breast, 15 cervical or endometrial, 10 gastrointestinal, and 8 lung adenocarcinomas and 25 malignant mesotheliomas (MMs). Specimens were analyzed for claudin-1 and claudin-3 expression using immunohistochemical...

journal_title：American journal of clinical pathology

authors： Kleinberg L,Holth A,Fridman E,Schwartz I,Shih IeM,Davidson B

更新日期：2007-06-01 00:00:00

abstract：:Mantle cell lymphoma (MCL) is characterized by typical morphologic features and the CD5+, CD23-immunophenotype. However, some morphologically typical MCLs are CD23+. A t(11;14)(q13;q32) translocation is frequently found in MCL, leading to overexpression of cyclin D1. We studied the expression of cyclin D1 in 50 small ...

journal_title：American journal of clinical pathology

authors： Peghini PE,Fehr J

更新日期：2002-02-01 00:00:00

abstract：:An antithrombin assay (AA) and an antithrombin assay modified by the addition of heparin (H-AA) were performed using sera from healthy subjects, patients predisposed to thrombosis, and patients with thromboembolic disease. Characteristic AA, and H-AA patterns were found in each group. Normal controls and four of 39 "p...

journal_title：American journal of clinical pathology

authors： Innerfield I,Stone ML,Mersheimer W,Clauss RD,Greenberg J

更新日期：1976-03-01 00:00:00

abstract：:Characteristically, mantle cell lymphoma (MCL) expresses surface immunoglobulin (sIg), CD19, CD20, and CD5 and lacks CD10 and CD23. Rare CD5-MCL variants have been described. This report describes a case of leukemic MCL with morphologically and immunophenotypically distinct classic MCL and blastoid-variant MCL (BV-MCL...

journal_title：American journal of clinical pathology

authors： Morice WG,Hodnefield JM,Kurtin PJ,Hanson CA

更新日期：2004-07-01 00:00:00

abstract：:A 73-year-old man with myelodysplastic syndrome developed during the course of his illness auto-immune hemolytic anemia. The association between auto-immune hemolysis and myeloproliferative disease is extremely rare. An even more unique finding is the nature of the antibody which demonstrated single specificity agains...

journal_title：American journal of clinical pathology

authors： Sacher RA,McGinniss MM,Shashaty GG,Jacobson RJ,Rath CE

更新日期：1982-03-01 00:00:00

abstract：:We evaluated the immunohistochemical profile and specificity of CD138 reactivity in 238 specimens from hematopoietic and nonhematopoietic neoplasms. In 91 bone marrow biopsies, CD138 reactivity was observed for nonneoplastic plasma cells, neoplastic plasma cells in multiple myeloma cases (43/43), and the plasmacytic c...

journal_title：American journal of clinical pathology

authors： O'Connell FP,Pinkus JL,Pinkus GS

更新日期：2004-02-01 00:00:00

abstract：:Non-Hodgkin lymphoma (NHL) is more likely to develop in patients with Hodgkin disease (HD) than in the general population. Although reports of synchronous or metachronous HD and NHL are not uncommon in the literature, the biologic relationship of these 2 malignant neoplasms often is unclear. A larger-than-expected fra...

journal_title：American journal of clinical pathology

authors： Brown JR,Weng AP,Freedman AS

更新日期：2004-05-01 00:00:00

abstract：:Primary thymic epithelial neoplasms have been the subject of much controversy in recent years owing to the difficulties posed by these tumors for precise histopathologic typing and prognostication. A number of classification schemes using different terminology have been proposed, none of which has satisfactorily manag...

journal_title：American journal of clinical pathology

authors： Suster S,Moran CA

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVES:Our aim was to investigate the frequency of steatohepatitic morphology in hepatocellular adenoma (HCA) and correlate with its clinical parameters and risk factors underlying nonalcoholic fatty liver disease (NAFLD) or nonalcoholic steatohepatitis (NASH). METHODS:We examined a series of 41 liver resection sp...

journal_title：American journal of clinical pathology

authors： Liu Y,Zen Y,Yeh MM

更新日期：2020-09-08 00:00:00

abstract：:Physicians are often forced to make decisions about the use of laboratory resources without adequate access to earlier results and related supporting information. Less than optimal use of the laboratory may result. The authors developed and deployed a clinical workstation meant to provide ready access to laboratory in...

journal_title：American journal of clinical pathology

authors： Connelly DP,Sielaff BH,Willard KE

更新日期：1995-09-01 00:00:00

abstract：:A comparative evaluation of two commercial kits that detect antinuclear antibodies via indirect immunofluorescence was undertaken using an adult ambulatory population. The sensitivity and specificity of the kits were compared to determine which of the two was more efficient as a screening test for systemic lupus eryth...

journal_title：American journal of clinical pathology

authors： Valdiserri RO,Petronie JS

更新日期：1984-03-01 00:00:00