Frozen-Section Checklist Implementation Improves Quality and Patient Safety.

Abstract:

OBJECTIVES:An intraoperative consultation (IOC) checklist was developed and implemented aimed at standardizing slide labeling and monitoring metrics central to quality and safety in surgical pathology. DESIGN:Data were collected for all IOC cases over a 9-month period. Slide labeling defect rates and IOC turnaround time (TAT) were recorded and compared for the pre- and postimplementation periods. RESULTS:In total, 839 IOC cases were analyzed. Preintervention slide labeling showed that 85% of cases contained at least one defect (n = 565). Postintervention data revealed that 27% of cases contained at least one defect (n = 274). The improvement was statistically significant (P < .001). Mean TAT was 21.6 minutes preintervention vs 23.2 minutes postintervention, and the change was insignificant (P = .071). CONCLUSIONS:The implementation of a standardized IOC reduced slide labeling error. This improvement did not affect mean TAT and may have the increased quality of IOC TAT data reporting. Other metrics affecting patient safety and quality were monitored and standardized.

journal_name

Am J Clin Pathol

authors

Chen Y,Anderson KR,Xu J,Goldsmith JD,Heher YK

doi

10.1093/ajcp/aqz009

subject

Has Abstract

pub_date

2019-05-03 00:00:00

pages

607-612

issue

6

eissn

0002-9173

issn

1943-7722

pii

5399023

journal_volume

151

pub_type

杂志文章
  • Radioimmunoassays for protein C and factor X. Plasma antigen levels in abnormal hemostatic states.

    abstract::Specific radioimmunoassays, sensitive to plasma levels of less than 1% of normal, were developed for protein C and Factor X. In 31 normal subjects, mean plasma antigen levels were as follows: protein C, 3.23 +/- 0.79 microgram/mL (2 SD); Factor X, 7.74 +/- 1.81 microgram/mL. In patient son chronic warfarin therapy, pr...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/82.5.573

    authors: Epstein DJ,Bergum PW,Bajaj SP,Rapaport SI

    更新日期:1984-11-01 00:00:00

  • Distribution and incidence of viridans streptococcal species in routine clinical specimens.

    abstract::Five hundred consecutive isolates of viridans streptococci were identified to the species level in an effort to determine their distribution and incidence in routine clinical specimens. Viridans streptococci accounted for significant percentages of streptococcal isolates from urine, wounds, body fluids, and blood. The...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/80.6.854

    authors: Ruoff KL,Fishman JA,Calderwood SB,Kunz LJ

    更新日期:1983-12-01 00:00:00

  • Analysis of heparinization methods during hemodialysis.

    abstract::The ideal method of heparinization should achieve therapeutic concentrations (0.2-0.5 IU/mL) in the artificial kidney and the least possible amount of heparin in the patient. Total heparinization using a bolus dose (8400 IU) followed by continuous infusion of heparin (20 IU/min), initially showed 1.4-2.4 IU/mL in the ...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/84.3.317

    authors: Talstad I,Kjelby K

    更新日期:1985-09-01 00:00:00

  • Comparison of next-generation sequencing and mutation-specific platforms in clinical practice.

    abstract:OBJECTIVES:To compare next-generation sequencing (NGS) platforms with mutation-specific analysis platforms in a clinical setting, in terms of sensitivity, mutation specificity, costs, capacity, and ease of use. METHODS:We analyzed 25 formalin-fixed, paraffin-embedded lung cancer samples of different size and tumor per...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/AJCP40XETVYAMJPY

    authors: Hinrichs JW,van Blokland WT,Moons MJ,Radersma RD,Radersma-van Loon JH,de Voijs CM,Rappel SB,Koudijs MJ,Besselink NJ,Willems SM,de Weger RA

    更新日期:2015-04-01 00:00:00

  • Postmortem bacteriology and pneumonia in a mentally retarded population.

    abstract::Postmortem pathologic and bacteriologic reports were analyzed for 237 deaths occurring at a large institution for the mentally retarded from 1958 to 1973. Bronchopneumonia, aspiration pneumonia, and lipid pneumonia were frequently reported at autopsy, and in a total of 146 cases (61.6%) at least one type of pneumonia ...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/67.2.190

    authors: Polednak AP

    更新日期:1977-02-01 00:00:00

  • Ameloblastoma of the maxilla with distant metastases and hypercalcemia.

    abstract::A case of metastatic ameloblastoma of the maxilla with secondary hypercalcemia in a 54-year-old man is presented. After treatment with surgery, chemotherapy, and radiotherapy, the patient was found to have multiple metastases and severe hypercalcemia associated with high levels of parathormone-like substance in the pe...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/75.4.585

    authors: Madiedo G,Choi H,Kleinman JG

    更新日期:1981-04-01 00:00:00

  • In vitro assessment of platelet damage during rotator storage.

    abstract::The measurement of beta-thromboglobulin (BTG) and platelet lactic dehydrogenase (LDH) as markers for alpha-granule release and platelet lysis, respectively, has been reported to correlate with the amount of damage incurred during the preparation and storage of platelet concentrates. We compared the concentrations of t...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/79.6.719

    authors: Kalmin ND,Wilson MJ,Liles BA

    更新日期:1983-06-01 00:00:00

  • Proliferative activity in non-Hodgkin's lymphomas. A comparison of the bromodeoxyuridine labeling index with PCNA immunostaining and quantitative image analysis.

    abstract::Cellular proliferation is being evaluated as an independent prognostic indicator in a variety of tumors, including non-Hodgkin's lymphomas (NHL). Although the labeling index (LI), using either tritiated thymidine or monoclonal antibodies to bromodeoxyuridine, is considered to be the gold standard of cell kinetic measu...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/99.6.668

    authors: Sebo TJ,Roche PC,Witzig TE,Kurtin PJ

    更新日期:1993-06-01 00:00:00

  • Evaluation of the status of laboratory practices and the need for continuing education in medical mycology.

    abstract::A survey to determine the need for training in medical mycology was sent to 605 US laboratories. Training needs were determined by comparing actual laboratory mycology practices with recommended practices, documenting the extent of mycology training reported by employees, and asking respondents to specify the fungi th...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/RR95-P7DN-41LW-1LGQ

    authors: Rosner ER,Reiss E,Warren NG,Shadomy HJ,Lipman HB

    更新日期:2002-08-01 00:00:00

  • Community-acquired bacteremic Achromobacter xylosoxidans type IIIa pneumonia in a patient with idiopathic IgM deficiency.

    abstract::A man was hospitalized with bacteremic Achromobacter xylosoxidans type IIIa pneumonia. The authors are aware of no previously reported similar infections caused by this bacterium. A clinical cure was achieved with a combination of carbenicillin and kanamycin therapy. Microtiter susceptibility testing revealed that car...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/70.4.712

    authors: Dworzack DL,Murray CM,Hodges GR,Barnes WG

    更新日期:1978-10-01 00:00:00

  • The immunochemical characterization of the light chains in the mesangial IgA deposits in IgA nephropathy.

    abstract::The immunochemical characterization of the light chains of the mesangial immunoglobulin A (IgA) deposits were studied in 45 patients with IgA nephropathy. Kappa and lambda light chains were detected with direct immunofluorescence (IF) method, using monospecific rabbit anti-human anti-kappa and anti-lambda anti-sera. T...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/85.5.548

    authors: Lai KN,Chan KW,Mac-Moune F,Ho CP,Yan KW,Lam CW,Vallance-Owen J

    更新日期:1986-05-01 00:00:00

  • Expression of messenger RNA of the cardiac isoforms of troponin T and I in myopathic skeletal muscle.

    abstract::In the absence of clinical signs, elevated values of the cardiac isoforms of troponin T (cTnT) and I (cTnI) can be found in the serum samples of some patients with skeletal muscle myopathies; the cause is unclear. We studied the messenger RNA (mRNA) expression of cTnT and cTnI in the skeletal muscles of 24 patients wi...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:

    authors: Messner B,Baum H,Fischer P,Quasthoff S,Neumeier D

    更新日期:2000-10-01 00:00:00

  • Hodgkin's disease of the esophagus.

    abstract::A 61-year-old man with acquired immunodeficiency syndrome (AIDS) sought care because of the onset of progressive dysphagia. He was found to have a perforated, fungating esophageal mass. The combined histologic and immunologic findings were diagnostic of Hodgkin's disease, nodular sclerosis type, lymphocyte-depleted va...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/108.5.593

    authors: Gelb AB,Medeiros LJ,Chen YY,Weiss LM,Weidner N

    更新日期:1997-11-01 00:00:00

  • Forty Postmortem Examinations in COVID-19 Patients.

    abstract:OBJECTIVES:Although diffuse alveolar damage, a subtype of acute lung injury (ALI), is the most common microscopic pattern in coronavirus disease 2019 (COVID-19), other pathologic patterns have been described. The aim of the study was to review autopsies from COVID-19 decedents to evaluate the spectrum of pathology and ...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/aqaa156

    authors: De Michele S,Sun Y,Yilmaz MM,Katsyv I,Salvatore M,Dzierba AL,Marboe CC,Brodie D,Patel NM,Garcia CK,Saqi A

    更新日期:2020-11-04 00:00:00

  • DNA typing of the human MN and Ss blood group antigens in amniotic fluid and following massive transfusion.

    abstract::Although red blood cell (RBC) antigen typing by agglutination is generally useful, several situations exist where this approach is difficult or impossible. For example, following a massive transfusion, a patient's residual RBCs are mixed with transfused normal donor RBCs. In this case, typing by hemagglutination prima...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/103.3.353

    authors: Eshleman JR,Shakin-Eshleman SH,Church A,Kant JA,Spitalnik SL

    更新日期:1995-03-01 00:00:00

  • How to Teach Laboratory Stewardship in the Undergraduate Medical Curriculum?

    abstract:OBJECTIVES:Promotion of high-quality care at a lower cost requires educational initiatives across the continuum of medical education. A needs assessment was performed to inform the design of an educational tool with the goal of teaching laboratory stewardship to medical students. METHODS:The needs assessment consisted...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/aqz102

    authors: Roth CG,Huang WY,Caruso AC,Sekhon N,Kung DH,Greely JT,Du YB,Holder-Haynes JG,Little JE,Fielder EK,Ismail NJ

    更新日期:2020-01-01 00:00:00

  • Decreased T-lymphocytes in patients with mammary cancer.

    abstract::The levels of thymus-derived lymphocytes (T-cells) in samples of peripheral blood from 47 patients with carcinoma of the breast, 36 patients with benign mammary lesions, and 33 matched normal controls were determined. Results were analyzed with three statistical tests. It was found that the mean percentages of T-lymph...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/65.4.445

    authors: Keller SE,Ioachim HL,Pearse T,Siletti DM

    更新日期:1976-04-01 00:00:00

  • Identification of methicillin-resistant staphylococci by multiplex polymerase chain reaction assay.

    abstract::A multiplex polymerase chain reaction (PCR) assay using oligonucleotide primers to detect mecA and 16S ribosomal RNA gene was developed to aid in identification of methicillin-resistant staphylococci. Validation included 99 isolates of staphylococcus grouped into one of five categories: methicillin-susceptible coagula...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/107.3.368

    authors: Salisbury SM,Sabatini LM,Spiegel CA

    更新日期:1997-03-01 00:00:00

  • The risk of metachronous neoplasia in patients with serrated adenoma.

    abstract::Serrated adenomas are the precursors of at least 5.8% of colorectal cancers; otherwise little is known of their clinical significance in comparison with conventional adenomas and hyperplastic polyps. We compared the risk of metachronous lesions in colorectal serrated adenomas, conventional adenomas, and hyperplastic p...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/VBAG-V3BR-96N2-EQTR

    authors: Lazarus R,Junttila OE,Karttunen TJ,Mäkinen MJ

    更新日期:2005-03-01 00:00:00

  • Immunohistochemical characterization of pulmonary blastoma.

    abstract::The immunohistochemical staining patterns of three pulmonary blastomas (PBs) were studied for markers of mesenchymal (vimentin, muscle-specific actin) and epithelial (cytokeratin, epithelial membrane antigen) differentiation to clarify their phenotypic nature and, possibly, their histogenesis. Epithelial markers were ...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/89.6.773

    authors: Berean K,Truong LD,Dudley AW Jr,Cagle PT

    更新日期:1988-06-01 00:00:00

  • Differential characterization of the "reticulum cell" in lymphoreticular neoplasms.

    abstract::Differential characterization of the "reticulum cell" in lymphoreticular neoplasms. Am J Clin Pathol. 64: 171-179, 1975. The term "reticulum cell" is confusing, having been applied to the cells involved in many hematopoietic neoplasms, such as reticulum-cell sarcoma, histiocytic medullary reticulosis, leukemic reticul...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/64.2.171

    authors: Yam LT,Tavassoli M,Jacobs P

    更新日期:1975-08-01 00:00:00

  • A civilian case of fatal meningococcemia due to Neisseria meningitidis, group Y.

    abstract::The present report is that of a civilian episode of fatal, fulminant group Y meningococcemia in a previously healthy adolescent, who denied prior vaccination against group C meningococcus. The patient suffered abrupt onset of purpura, hypotension and cardiopulmonary arrest. A detailed clinical and pathologic report is...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/68.2.296

    authors: Bernad PG,Snyder DA,Levey M

    更新日期:1977-08-01 00:00:00

  • Ischemia-modified albumin improves the usefulness of standard cardiac biomarkers for the diagnosis of myocardial ischemia in the emergency department setting.

    abstract::We studied the role of ischemia-modified albumin (IMA) with standard biomarkers (myoglobin, creatine kinase-MB [CK-MB], troponin I [TnI]) in assessment of 200 patients with suspected myocardial ischemia admitted to the emergency department. Every case was reviewed by a cardiologist. A clinical diagnosis of ischemia wa...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/4bctg5ucymqfwblr

    authors: Anwaruddin S,Januzzi JL Jr,Baggish AL,Lewandrowski EL,Lewandrowski KB

    更新日期:2005-01-01 00:00:00

  • Group-specific component (Gc) alleles among Haitian immigrants.

    abstract::Gc allele frequencies were determined in Haitian immigrants, a group at high risk for AIDS. Gc2, an allele associated with disease resistance, is infrequent in this group; Gc1f is frequent. ...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/90.3.371

    authors: Wenk RE,Russo F

    更新日期:1988-09-01 00:00:00

  • Mucocele-like lesions diagnosed on breast core biopsy: assessment of upgrade rate and need for surgical excision.

    abstract::Mucocele-like lesion (MLL) is a rare mucinous lesion of the breast with highly variable upgrade rates to atypia or malignancy on excision. This spectrum of data has led to differing opinions on the need for surgical excision. We evaluated 50 core biopsy specimens diagnosed as having MLLs and correlated the findings wi...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/AJCP1D8YLCFFTLOW

    authors: Sutton B,Davion S,Feldman M,Siziopikou K,Mendelson E,Sullivan M

    更新日期:2012-12-01 00:00:00

  • Myelodysplasia in the acquired immune deficiency syndrome.

    abstract::Certain new hematologic findings in eight homosexual or bisexual patients with the acquired immune deficiency syndrome (AIDS) are presented. All eight patients manifested a normochromic, normocytic anemia, and six of eight had granulocytopenia during their hospitalization. The other two had low-normal granulocyte coun...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/84.2.144

    authors: Schneider DR,Picker LJ

    更新日期:1985-08-01 00:00:00

  • Babesiosis: problems in diagnosis using autoanalyzers.

    abstract::A 76-year-old white man previous diagnosed as having Waldenstrom's macroglobulinemia continued with persistent fevers and sweats for two and a half years. Recently, repeated automated differentials during 11 days of hospitalization failed to note any intracellular inclusions in the RBCs. Blood sent to the Microbiology...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/83.4.520

    authors: Bruckner DA,Garcia LS,Shimizu RY,Goldstein EJ,Murray PM,Lazar GS

    更新日期:1985-04-01 00:00:00

  • Hepatic ALECT-2 amyloidosis causing portal hypertension and recurrent variceal bleeding: a case report and review of the literature.

    abstract:OBJECTIVES:To examine laser microdissection and mass spectrometry (LMD-MS), which has emerged as a new tool to aid in typing amyloid proteins. RESULTS:ALECT-2 is a potential cause of hepatic amyloidosis best detected by LMD-MS. METHODS:One of the more recently reported proteins is ALECT-2 (leukocyte cell-derived chem...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章,评审

    doi:10.1309/AJCPCLK54RKXTRDI

    authors: Damlaj M,Amre R,Wong P,How J

    更新日期:2014-02-01 00:00:00

  • The usefulness of immunohistochemistry in the diagnosis of follicular lymphoma in bone marrow biopsy specimens.

    abstract::We used a panel of paraffin antibodies to determine whether neoplastic and nonneoplastic lymphoid aggregates in the bone marrow can be distinguished reliably. Formalin-fixed, paraffin-embedded bone marrow core biopsy specimens with lymphoid aggregates were stained using primary antibodies directed against bcl-2, bcl-6...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/W3QX-WJ1C-WG2K-225V

    authors: West RB,Warnke RA,Natkunam Y

    更新日期:2002-04-01 00:00:00

  • Intratumoral DNA content variability. A study of non-small cell lung cancer.

    abstract::Twenty-eight resected primary non-small cell lung carcinomas were studied for intratumoral DNA variability by flow cytometry (FCM). Three separate tissue specimens from each resected tumor were divided equally for FCM analysis and histologic evaluation. FCM analysis also was performed on fine-needle aspirates (FNAs) f...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/96.3.311

    authors: Sara A,el-Naggar AK

    更新日期:1991-09-01 00:00:00