Myelodysplasia in the acquired immune deficiency syndrome.

abstract：:Chemotherapy is a well-established therapeutic approach for several malignancies, but its clinical efficacy is often limited by its related cardiotoxicity, which leads to cardiomyopathy, possibly evolving into heart failure. To detect cardiac damage, the adopted diagnostic approach is the estimation of left ventricula...

journal_title：American journal of clinical pathology

authors： Dolci A,Dominici R,Cardinale D,Sandri MT,Panteghini M

更新日期：2008-11-01 00:00:00

abstract：:Chronic myeloproliferative diseases (MPDs) are not associated with consistent cytogenetic or molecular abnormalities. Demonstration of clonal cell growth by analysis of X-chromosome inactivation (XCI) patterns in females provides a promising tool for diagnosis. However, this technique can be complicated by excessive l...

journal_title：American journal of clinical pathology

authors： Mitterbauer G,Winkler K,Gisslinger H,Geissler K,Lechner K,Mannhalter C

更新日期：1999-07-01 00:00:00

abstract：:A number of genetic abnormalities have been detected in multiple myeloma (MM) using cytogenetic techniques. The prominent abnormalities are deletions of 13q and translocations affecting the IgH locus on 14q32. The recurrence of chromosomal abnormalities in MM suggests a specific role for them concerning its pathogenes...

journal_title：American journal of clinical pathology

authors： Tchinda J,Volpert S,Kropff M,Berdel WE,Kienast J,Meinhardt F,Horst J

更新日期：2004-12-01 00:00:00

abstract：:Centerin (SERPINA9/GCET1) is a protease inhibitor with expression restricted to germinal center B cells and lymphoid malignancies with germinal center B-cell maturation. Expression of the centerin gene transcript, along with bcl-6 and GCET2/HGAL, constitutes a molecular signature associated with a good prognosis in di...

journal_title：American journal of clinical pathology

authors： Paterson MA,Hosking PS,Coughlin PB

更新日期：2008-07-01 00:00:00

abstract：:Pathologists are expected to accurately diagnose increasingly smaller breast carcinomas. Correct classification (ie, lobular vs ductal or in situ vs invasive) directly affects subsequent management, especially when the focus is near a surgical margin or present in a needle core biopsy and is further challenging if the...

journal_title：American journal of clinical pathology

authors： Ross DS,Liu YF,Pipa J,Shin SJ

更新日期：2013-01-01 00:00:00

abstract：:Cultures from the gallbladder and blood of a 60-year-old man with acute cholecystitis grew Haemophilus aphrophilus. This organism, an unusual isolate in clinical specimens, is most frequently seen in patients with either endocarditis or brain abscesses. Haemophilus aphrophilus may be distinguished from Eikenella corro...

journal_title：American journal of clinical pathology

authors： Huck W,Britt MR

更新日期：1978-03-01 00:00:00

abstract：:Counterimmunoelectrophoresis was used to detect Cryptococcus neoformans capsular polysaccharide in the body fluids of infected patients. Using rabbit anti-C. neoformans A15 globulin, counterimmunoelectrophoresis detected 1.25 microgram of purified cryptococcal polysaccharide per ml of cerebrospinal fluid (CSF) or urin...

journal_title：American journal of clinical pathology

authors： Maccani JE

更新日期：1977-07-01 00:00:00

abstract：:A primary hepatic tumor with histologic features suggestive of carcinoid tumor is reported, and six previously reported cases reviewed. Tumor cells contained electron dense secretory granules with an average diameter 150-200 nm which demonstrated positive argyrophilic reactions. On immunohistochemistry, chromogranin A...

journal_title：American journal of clinical pathology

authors： Miura K,Shirasawa H

更新日期：1988-04-01 00:00:00

abstract：:Utilizing a bacterial-agar overlay technic incorporating the methionine-requiring bacterium Leukonostoc mesenteroides, little or no bacterial growth was seen surrounding the megaloblasts and proerythroblasts of eight patients who had severe untreated pernicious anemia. Similarly, scant bacterial growth was observed in...

journal_title：American journal of clinical pathology

authors： Kass L

更新日期：1976-04-01 00:00:00

abstract：:The Sysmex R-3000 (TOA Medical Electronics, Kobe, Japan) evaluates maturation of reticulocytes by quantitating the fraction of reticulocytes within low-, middle-, and high-fluorescence intensity regions. We defined the immature reticulocyte fraction (IRF) as the sum of the fraction of high-fluorescence intensity regio...

journal_title：American journal of clinical pathology

authors： Chang CC,Kass L

更新日期：1997-07-01 00:00:00

abstract：:We noticed almost routine disparate results in margin lengths when colorectal specimens are measured in vivo by the surgeon and in vitro by the pathologist. We studied 26 sigmoid and rectum specimens to document the amount of organ shrinkage after surgical removal and fixation. Each specimen had a 5.0-cm segment at ea...

journal_title：American journal of clinical pathology

authors： Goldstein NS,Soman A,Sacksner J

更新日期：1999-03-01 00:00:00

abstract：:The pattern of spurious red blood cell parameters caused by serum cold agglutinins has been well characterized for the Coulter counters but not the Ortho ELT-8. The pattern consists of a spurious increase in mean corpuscular volume (MCV), a discrepancy between the hemoglobin and the hematocrit, the latter falsely redu...

journal_title：American journal of clinical pathology

authors： Solanki DL,Blackburn BC

更新日期：1985-02-01 00:00:00

abstract：:A case of metastatic squamous cell carcinoma to bone was studied using immunoperoxidase methods for Factor VIII-related antigen, producing positive staining in the tumor cells. Electron microscopy proved the squamous nature of the tumor, and, subsequently, a pulmonary primary tumor was found. Testing of additional tum...

journal_title：American journal of clinical pathology

authors： Wilson AJ

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVES:To investigate metastasis associated in colon cancer 1 (MACC1) and MET expression in colorectal adenoma, Tis, early-stage invasive (T1 and T2), and advanced adenocarcinoma with liver metastasis using immunohistochemistry. METHODS:Ninety-three paraffin-embedded colorectal tumor specimens were immunohistochem...

journal_title：American journal of clinical pathology

authors： Ren B,Zakharov V,Yang Q,McMahon L,Yu J,Cao W

更新日期：2013-11-01 00:00:00

abstract：:The polymerase chain reaction (PCR) is a newly developed molecular biology technique that can significantly amplify DNA or RNA. The process consists of repetitive cycles of specific DNA synthesis, defined by short stretches of preselected DNA. With each cycle, there is a doubling of the final, desired DNA product such...

journal_title：American journal of clinical pathology

authors： Remick DG,Kunkel SL,Holbrook EA,Hanson CA

更新日期：1990-04-01 00:00:00

abstract：:The purpose of our study was to improve the quality of care in an emergency department (ED) as measured by length of stay (LOS), total turnaround time (TAT) for laboratory result reporting, and the blood culture contamination rate. Data were included for patients who had at least 1 of 5 laboratory tests performed as p...

journal_title：American journal of clinical pathology

authors： Sheppard C,Franks N,Nolte F,Fantz C

更新日期：2008-10-01 00:00:00

abstract：:By application of combined structural and functional analyses, most lymphoid neoplasms may be categorized as of T- or B-cell origin. T lymphocyte neoplasms include types of acute and chronic lymphocytic leukemias, certain cutaneous and node-based lymphomas, and lymphomas of thymocytes (convoluted lymphocytic lymphomas...

journal_title：American journal of clinical pathology

authors： Collins RD,Waldron JA,Glick AD

更新日期：1979-10-01 00:00:00

abstract：:Data from 2.5 million glucose analyses on pools of lyophilized human quality control serum were used to evaluate analyte stability in the prereconstitution phase. Input information was from laboratories in Regional Quality Control Programs that use CAP Quality Assurance Service (QAS) data processing. Of 31 pools in us...

journal_title：American journal of clinical pathology

authors： Lawson NS,Haven GT,DiSilvio TV,Gilmore BF

更新日期：1982-10-01 00:00:00

abstract：OBJECTIVES:To characterize error rates for genetic test orders between medical specialties and in different settings by examining detailed order information. METHODS:We performed a retrospective analysis of a detailed utilization management case database, comprising 2.5 years of data and almost 1,400 genetic test orde...

journal_title：American journal of clinical pathology

authors： Mathias PC,Conta JH,Konnick EQ,Sternen DL,Stasi SM,Cole BL,Astion ML,Dickerson JA

更新日期：2016-08-01 00:00:00

abstract：:A case of signet ring cell lymphoma, a rare variant of follicular center cell lymphoma, is presented with a review of 20 other such lymphomas previously reported in the English literature. The histologic, immunocytologic, and electron microscopic features are described with speculation as to the possible relationship ...

journal_title：American journal of clinical pathology

authors： Silberman S,Fresco R,Steinecker PH

更新日期：1984-03-01 00:00:00

abstract：:To study the distribution and thromboembolic effect of Ultrafluid Lipiodol, 15 surgically removed hepatocellular carcinomas with selective intraarterial Lipiodol injection 7 to 10 days before surgery and 15 noninjected controls were studied radiologically and histologically. Tissue blocks were processed with an en blo...

journal_title：American journal of clinical pathology

authors： Arnold MM,Kreel L,Wallace AC,Li AK

更新日期：1992-03-01 00:00:00

abstract：:Previous reports have indicated that patients with severe acute respiratory syndrome (SARS)-associated coronavirus infection could develop atypical pneumonia with fulminant pulmonary edema. However, the target cells of SARS viral infection have not been characterized in detail. We report the pathologic findings of the...

journal_title：American journal of clinical pathology

authors： Chow KC,Hsiao CH,Lin TY,Chen CL,Chiou SH

更新日期：2004-04-01 00:00:00

abstract：:For quality-control purposes, federal regulations require cytology laboratories to compare Papanicolaou smear and cervical biopsy reports, if available, and determine the cause of any discrepancies. The authors reviewed 56,497 cervicovaginal smears, of which 1,582 (2.8%) had a subsequent cervical biopsy or endocervica...

journal_title：American journal of clinical pathology

authors： Joste NE,Crum CP,Cibas ES

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVES:We postulated that lymph node (LN) harvest and LN size are influenced by immunologic effects. METHODS:To investigate this hypothesis, we performed a retrospective analysis of 170 node-negative colon cancer cases to evaluate the density of intratumoral T lymphocytes (ITLs). CD3- and CD8-positive T cells were...

journal_title：American journal of clinical pathology

authors： Märkl B,Wieberneit J,Kretsinger H,Mayr P,Anthuber M,Arnholdt HM,Schenkirsch G

更新日期：2016-06-01 00:00:00

abstract：:We describe the development and testing of a novel pre-sign-out quality assurance tool for case diagnoses that allows for the random review of a percentage of cases by a second pathologist before case verification and release of the final report. The tool incorporates the ability to record and report levels of diagnos...

journal_title：American journal of clinical pathology

authors： Owens SR,Dhir R,Yousem SA,Kelly SM,Piccoli A,Wiehagen L,Lassige K,Parwani AV

更新日期：2010-06-01 00:00:00

abstract：:We analyzed the value in cervical cytology of a recently developed technique by which it is possible to remove thick tissue specimens, called microbiopsies, from cervical smears and to process them for histologic examination. In 12 (48%) of 25 cervical smears in which microbiopsies were found, the histologic sections ...

journal_title：American journal of clinical pathology

authors： Mravunac M,Verbeek DH,Sanders-Eras M,Besseling R,Wijnen-Dubbers C,Smedts F

更新日期：1997-08-01 00:00:00

abstract：:The role of the HER2 receptor remains uncertain in the pathogenesis and progression of human prostate cancer. Previous studies have reported widely divergent rates for HER2 expression in primary prostate tumors, probably owing to significant methodologic differences in the studies. Few data exist about the frequency o...

journal_title：American journal of clinical pathology

authors： Reese DM,Small EJ,Magrane G,Waldman FM,Chew K,Sudilovsky D

更新日期：2001-08-01 00:00:00

abstract：:A new disposable bleeding time device (Hemalet) was tested in 20 normal individuals and 11 patients with various bleeding disorders. The results were compared with those of Simplate II. The mean bleeding time for normal individuals was 5.4 +/- 1.5 (mean +/- 1 SD) minutes by Hemalet and 5.8 +/- 1.4 (mean +/- 1 SD) minu...

journal_title：American journal of clinical pathology

authors： Toomey KC,Kim HC,Kosmin M,Saidi P

更新日期：1986-05-01 00:00:00

abstract：:High-volume (200 ml) platelet concentrates prepared by discontinuous-flow centrifugation, with counts as high as ca. 2.0 x 10(12)/l, were stored in either 600 ml-capacity polyvinylchloride bags or 800-ml capacity polyethylene bags. Both polyvinylchloride and polyethylene bags appeared adequate for 24-hour storage of p...

journal_title：American journal of clinical pathology

authors： Rosenstein R,Lawe JE,North JG

更新日期：1980-03-01 00:00:00

abstract：:Cervical cone biopsy has become an important surgical procedure for endocervical adenocarcinoma in situ (AIS), especially for patients who desire to retain their fertility. Establishing the usefulness of the endocervical margin status in cone biopsy specimens as a predictor of residual AIS is paramount. We examined th...

journal_title：American journal of clinical pathology

authors： Goldstein NS,Mani A

更新日期：1998-06-01 00:00:00