Abstract：
:Cervical cone biopsy has become an important surgical procedure for endocervical adenocarcinoma in situ (AIS), especially for patients who desire to retain their fertility. Establishing the usefulness of the endocervical margin status in cone biopsy specimens as a predictor of residual AIS is paramount. We examined the status of the endocervical margin in the cone biopsy specimen, the distance between the most proximal AIS and the endocervical margin in the cone biopsy specimen, and the endocervical curettage (ECC) specimen performed at the time of cone biopsy and residual AIS in the hysterectomy specimens of 61 patients with specimens accessioned from 1968 through 1997; 43 (30%) of patients with a negative endocervical margin had residual AIS in the hysterectomy specimen. Conversely, 10 of 18 (56%) patients with a positive endocervical margin in the cone biopsy specimen had no AIS in the hysterectomy specimen. All 6 patients with AIS in the ECC specimen had residual AIS. No patient with an endocervical margin in the cone biopsy specimen greater than 10 mm had residual AIS. Patients with distances less than 10 mm had equal percentages of residual AIS. In general, more patients with a negative endocervical margin in the cone biopsy specimen had no residual AIS in the hysterectomy specimen than those with a positive endocervical margin in the cone biopsy specimen. However, the status of this margin is not useful for predicting the presence of residual AIS. Pathologists should report the distance between the endocervical cone biopsy margin and the closest AIS.
journal_name
Am J Clin Patholjournal_title
American journal of clinical pathologyauthors
Goldstein NS,Mani Adoi
10.1093/ajcp/109.6.727subject
Has Abstractpub_date
1998-06-01 00:00:00pages
727-32issue
6eissn
0002-9173issn
1943-7722journal_volume
109pub_type
杂志文章abstract：:We evaluated a comprehensive deidentification engine at the University of Pittsburgh Medical Center (UPMC), Pittsburgh, PA, that uses a complex set of rules, dictionaries, pattern-matching algorithms, and the Unified Medical Language System to identify and replace identifying text in clinical reports while preserving ...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1309/E6K3-3GBP-E5C2-7FYU
更新日期：2004-02-01 00:00:00
abstract：:Thrombocytosis may reflect a primary myeloproliferative disorder or be a secondary reaction to other pathologic processes. Patients with persistent unexplained thrombocytosis meeting criteria of primary thrombocythemia had elevated levels of serum lactic dehydrogenase, whereas comparable patients with secondary thromb...
journal_title：American journal of clinical pathology
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更新日期：1981-06-01 00:00:00
abstract：:Lesions of the breast containing extravasated mucin span a continuum from benign mucoceles to invasive mucinous (colloid) carcinoma. It is well known that distinguishing benign from malignant mucinous lesions is difficult infine-needle aspiration material. Whether these lesions also are difficult to distinguish in cor...
journal_title：American journal of clinical pathology
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更新日期：2002-07-01 00:00:00
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journal_title：American journal of clinical pathology
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更新日期：2004-11-01 00:00:00
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journal_title：American journal of clinical pathology
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journal_title：American journal of clinical pathology
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更新日期：1985-03-01 00:00:00
abstract：Objectives:To evaluate the prognostic values of microRNAs (miRNAs) in glioblastoma, and to see if there is an association between miRNAs and MGMT promoter methylation status. Methods:We collected paraffin blocks from resection specimens from 114 glioblastoma patients who had received temozolomide treatment and radioth...
journal_title：American journal of clinical pathology
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doi：10.1093/ajcp/aqy008
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journal_title：American journal of clinical pathology
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更新日期：2007-05-01 00:00:00
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journal_title：American journal of clinical pathology
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doi：10.1093/ajcp/74.5.651
更新日期：1980-11-01 00:00:00
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pub_type： 杂志文章
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更新日期：1989-12-01 00:00:00
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journal_title：American journal of clinical pathology
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doi：10.1309/AJCPP5YS2MVSKBYY
更新日期：2014-12-01 00:00:00
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journal_title：American journal of clinical pathology
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更新日期：1994-09-01 00:00:00
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journal_title：American journal of clinical pathology
pub_type： 杂志文章
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更新日期：1992-12-01 00:00:00
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doi：10.1093/ajcp/94.5.538
更新日期：1990-11-01 00:00:00
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journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/75.4.585
更新日期：1981-04-01 00:00:00
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journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/97.6.810
更新日期：1992-06-01 00:00:00
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journal_title：American journal of clinical pathology
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doi：10.1309/R2BC-2H7T-7KB6-0YG8
更新日期：2002-02-01 00:00:00
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journal_title：American journal of clinical pathology
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journal_title：American journal of clinical pathology
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更新日期：1995-07-01 00:00:00
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journal_title：American journal of clinical pathology
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doi：
更新日期：2005-01-01 00:00:00
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journal_title：American journal of clinical pathology
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更新日期：2005-06-01 00:00:00
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journal_title：American journal of clinical pathology
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更新日期：1984-06-01 00:00:00
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pub_type： 杂志文章
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更新日期：1981-10-01 00:00:00
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journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/74.6.795
更新日期：1980-12-01 00:00:00
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journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/101.5.559
更新日期：1994-05-01 00:00:00
abstract：OBJECTIVES:Assess support for the effectiveness of two separate practices, restrictive transfusion strategy and computerized physician order entry/clinical decision support (CPOE/CDS) tools, in decreasing RBC transfusions in adult surgical and nonsurgical patients. METHODS:Following the Centers for Disease Control and...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/aqz070
更新日期：2019-10-07 00:00:00
abstract：:The Leu-8 antigen is found on the surface of many hematologic cells, including many T- and B-lymphocytes. With the use of a frozen-section immunoperoxidase technic, 152 B-cell non-Hodgkin's lymphomas were examined for Leu-8 expression. Of these lymphomas, 53% expressed Leu-8. Subclassification of the lymphomas with th...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
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更新日期：1987-10-01 00:00:00
