Improving quality of patient care in an emergency department: a laboratory perspective.

abstract：:Breast cancer is the result of a multistage carcinogenic process. Initiation, promotion, dependency and autonomy make up a sequence of experimentally distinguishable phases of this process. Progression--the transition from dependency on hormonal support to autonomy--is demonstrable clinically. High-affinity saturatabl...

journal_title：American journal of clinical pathology

authors： Brennan MJ

更新日期：1975-12-01 00:00:00

abstract：:Over a four-month period, methanol was found in the blood of 18 patients among 687 sequential emergency room admissions screened for alcohols by gas chromatography. In the patients with positive results, blood ethanol ranged from 6 to 570 mg/dL (1.3-123.7 mmol/L), blood methanol from 2.3 to 4.0 mg/dL (0.72-1.25 mmol/L...

journal_title：American journal of clinical pathology

authors： Wargotz ES,Werner M

更新日期：1987-06-01 00:00:00

abstract：:Clotting tests based upon the activated partial thromboplastin time are disturbed by heparin. This brief communication shows that Factor XII clotting activity in plasma samples heparinized in vitro and in vivo can be measured accurately by means of an aPTT-test using congenitally deficient substrate plasma when the pl...

journal_title：American journal of clinical pathology

authors： Lämmle B,Tran TH,Duckert F

更新日期：1983-10-01 00:00:00

abstract：:Vitamin E has been reported to increase serum high-density lipoprotein (HDL) cholesterol. Given the known inverse relationship between HDL-cholesterol and risk of developing coronary artery disease, these preliminary results require verification or refutation. In the present study, 39 volunteers were given 600 U of vi...

journal_title：American journal of clinical pathology

authors： Howard DR,Rundell CA,Batsakis JG

更新日期：1982-01-01 00:00:00

abstract：:The Laboratory Proficiency Testing Program has been in effect for 20 years. During the past 6 years, samples were distributed for screening, investigation, and identification of hemoglobinopathies to test laboratory proficiency. Six samples for hemoglobin (Hb) S screening were distributed to from 37 to 163 laboratorie...

journal_title：American journal of clinical pathology

authors： Lafferty J,Ali MA,Carstairs K,Crawford L

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVES:MDM2 gene amplification is associated with well-differentiated (WDL) and dedifferentiated liposarcomas (DDL). Using fluorescent in situ hybridization (FISH), we sought to characterize various patterns of MDM2 amplification among the morphologic spectrum of liposarcoma. METHODS:Forty-six cases of liposarcoma...

journal_title：American journal of clinical pathology

authors： Ware PL,Snow AN,Gvalani M,Pettenati MJ,Qasem SA

更新日期：2014-03-01 00:00:00

abstract：:Histologic diagnosis of a nonpalpable breast lesion requires the following: (1) mammographically directed excision of the suspect lesion, (2) recovery of the target lesion from the tissue specimen, and (3) demonstration of the lesion in histologic section. Recovery of lesional tissue is a function of localization with...

journal_title：American journal of clinical pathology

authors： Alberhasky MT

更新日期：1989-10-01 00:00:00

abstract：:The "floral" variant of follicle center lymphoma (FCL) may be confused with progressive transformation of germinal centers or lymphocyte predominance Hodgkin lymphoma. Immunohistochemistry and gene rearrangement studies are usually sufficient to differentiate among these entities. We present 11 cases of floral FCL tha...

journal_title：American journal of clinical pathology

authors： Tiesinga JJ,Wu CD,Inghirami G

更新日期：2000-12-01 00:00:00

abstract：:Proliferative activity in astrocytomas, measured by image cytometry, was related to prognosis. Fifty-eight astrocytic neoplasms (grade 1 or 2, 11; grade 3, 31; glioblastoma multiforme, 16) were immunostained for Ki-67 (MIB-1; 1:50) and proliferating cell nuclear antigen (PCNA; prediluted). Proliferative activity (nucl...

journal_title：American journal of clinical pathology

authors： Kirkegaard LJ,DeRose PB,Yao B,Cohen C

更新日期：1998-01-01 00:00:00

abstract：:Heterogeneous expression or amplification is a challenge to HER2 diagnostics. A guideline defines heterogeneity as the presence of between 5% and 50% cells with HER2/CEP17 ratios of more than 2.20. We audited the frequency of such cells and their clinical impact in the results from 2 pathology laboratories combined wi...

journal_title：American journal of clinical pathology

authors： Bartlett AI,Starcyznski J,Robson T,Maclellan A,Campbell FM,van de Velde CJ,Hasenburg A,Markopoulos C,Seynaeve C,Rea D,Bartlett JM

更新日期：2011-08-01 00:00:00

abstract：:Anaerobiospirillum succiniciproducens is a little-known spiral bacterium. Presented here are two septicemia cases similar in that both occurred in rural northern Virginia, both patients presented with dental infection, and in both cases the organism was first suspected to be Campylobacter. The morphology, motility, bi...

journal_title：American journal of clinical pathology

authors： Park CH,Hixon DL,Endlich JF,O'Connell P,Bradd FT,Mount PM

更新日期：1986-01-01 00:00:00

abstract：:A test for the detection of antibodies to HTLV-III is available and will be widely used to screen donated blood to prevent transfusion-associated acquired immunodeficiency syndrome (AIDS). Based upon the sensitivity and specificity, the authors calculated the expected predictive values for different groups of asymptom...

journal_title：American journal of clinical pathology

authors： Sivak SL,Wormser GP

更新日期：1986-06-01 00:00:00

abstract：:To assess their applied clinical utility, viral cultures and serological tests for cytomegalovirus (CMV) were reviewed at Duke University Medical Center (DUMC), a 1,125-bed tertiary-care hospital. Less than 1% (3 of 1,216) of CMV cultures were positive, and 8% of serum samples (45 of 587) were positive by single sera ...

journal_title：American journal of clinical pathology

authors： Mangano WE,Gruninger RP

更新日期：1996-08-01 00:00:00

abstract：:Factor V Leiden (FVR506Q) is a genetic defect in the factor V (FV) molecule that confers resistance to proteolysis by activated protein C (APC) and is the most common abnormality detected in patients studied for hereditary thrombophilia. The initial screening test for this abnormality was a comparison of the activated...

journal_title：American journal of clinical pathology

authors： Akhtar MS,Blair AJ,King TC,Sweeney JD

更新日期：1998-04-01 00:00:00

abstract：:Basaloid squamous cell carcinoma (BSCC) and carcinosarcoma of the esophagus are rare entities, making up fewer than 2% of esophageal malignancies. Comparative genomic hybridization (CGH) in 1 case of BSCC and 2 cases of carcinosarcoma and subsequent array CGH in 1 case each of BSCC and carcinosarcoma revealed common c...

journal_title：American journal of clinical pathology

authors： Schaefer IM,Enders C,Polten A,Haller F,Frölich AM,Cameron S,Schüler P,Schweiger P,Gunawan B,Beham A,Füzesi L

更新日期：2011-04-01 00:00:00

abstract：:The cases of five patients who had sinus histiocytosis with massive lymphadenopathy accompanied by osseous involvement by the disease are presented. Four of the five patients were children. The bone lesions were multiple in four cases and solitary in one. The long bones were most commonly involved (three patients); ot...

journal_title：American journal of clinical pathology

authors： Walker PD,Rosai J,Dorfman RF

更新日期：1981-02-01 00:00:00

abstract：:A case of adenocarcinoma of the small bowel arising in pre-existing transmural ileitis (Crohn's disease) is reported and 28 previously reported cases are reviewed. Carcinoma associated with transmural enteritis occurs more often in the distal ileum, in younger patients, and in more males than expected from published d...

journal_title：American journal of clinical pathology

authors： Savage RA,Farmer RG,Hawk WA

更新日期：1975-02-01 00:00:00

abstract：:To establish the feasibility of immunotyping specimens transported over great distance, the University of Arizona and the Cleveland Clinic exchanged 39 lymphoma cases (26 B-cell, 13 T-cell cases) via air express for phenotyping. They were exchanged with the use of glass slides with adherent snap-frozen sections. The m...

journal_title：American journal of clinical pathology

authors： Grogan TM,Tubbs RR

更新日期：1987-04-01 00:00:00

abstract：:Several adulterants are used to mask tests for abused drugs in urine. Adulterants such as "Klear" and "Whizzies" contain potassium nitrite, and "Urine Luck" contains pyridinium chlorochromate (PCC). The presence of these adulterants cannot be detected by routine specimen integrity checks (pH, specific gravity, and tem...

journal_title：American journal of clinical pathology

authors： Dasgupta A,Wahed A,Wells A

更新日期：2002-02-01 00:00:00

abstract：:Neutrophil function was determined in resting and phagocytic cells by an assay of hexose monophosphate shunt activity performed on small volumes of whole blood. This new micromethod clearly differentiated between zymosan-stimulated and unstimulated hexose monophosphate shunt activity. Furthermore, the whole blood micr...

journal_title：American journal of clinical pathology

authors： King JW,McCall CE

更新日期：1980-07-01 00:00:00

abstract：:The results from fetal-maternal hemorrhage (FMH) detection and quantitation external quality assessment surveys conducted in Ontario indicate that the rosette test had a sensitivity and specificity for an FMH of more than 10 mL of 1.0 and 0.75, respectively, compared with 0.96 and 0.92, respectively, for acid elution....

journal_title：American journal of clinical pathology

authors： Lafferty JD,Raby A,Crawford L,Linkins LA,Richardson H,Crowther M

更新日期：2003-01-01 00:00:00

abstract：:Lymphocyte subpopulations in the intestinal tissues of seven patients with acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC) were studied by immunohistologic technics at two different locations, the small bowel and the rectum. Intraepithelial and lamina propria lymphocyte subsets stained with mon...

journal_title：American journal of clinical pathology

authors： Ellakany S,Whiteside TL,Schade RR,van Thiel DH

更新日期：1987-03-01 00:00:00

abstract：:Our objective was to assess the loss of E-cadherin (EC) as a diagnostic marker or a predictor of prognosis. We stained 276 breast carcinomas with monoclonal antibodies to EC (invasive lobular carcinomas [ILC] and variants, 59; invasive ductal carcinoma and ductal special types [IDC], 204; tubulolobular carcinoma [TLC]...

journal_title：American journal of clinical pathology

authors： Qureshi HS,Linden MD,Divine G,Raju UB

更新日期：2006-03-01 00:00:00

abstract：:The examination of T-cell receptor (TCR) repertoires has an important role in the study of lymphoproliferative disorders and autoimmune diseases. Analysis of the complementarity-determining region 3 (CDR3) of the TCR beta chain is used to assess the clonality of T-cell populations. We developed a rapid fluorescence-ba...

journal_title：American journal of clinical pathology

authors： Lue C,Mitani Y,Crew MD,George JF,Fink LM,Schichman SA

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVES:Myeloid and lymphoid neoplasms with abnormalities of fibroblast growth factor receptor 1 gene (FGFR1) are a rare and aggressive disease group that harbors translocations of FGFR1 with at least 14 recognized partner genes. We report a case of a patient with a novel t(17;21)(p13;q22) with RUNX1 rearrangement a...

journal_title：American journal of clinical pathology

authors： Kumar KR,Chen W,Koduru PR,Luu HS

更新日期：2015-05-01 00:00:00

abstract：:The API-20 Enteric Strip has been proposed to have the capacity to differentiate the nonfermentative gram-negative bacilli. This multitest strip serves as the basis of an evolving system, which first provided a Register, then a Selector, and more recently a computer Index. Twenty-three strains of Pseudomonas aeruginos...

journal_title：American journal of clinical pathology

authors： Morris MJ,Young VM,Moody MR

更新日期：1978-01-01 00:00:00

abstract：:Fine-needle aspiration (FNA) is the standard of care for the initial workup of thyroid nodules, but there is no consensus algorithm to manage patients with benign results. We examined performance characteristics of initial and repeat satisfactory FNAs for all 402 patients who underwent thyroid surgery during a recent ...

journal_title：American journal of clinical pathology

authors： Flanagan MB,Ohori NP,Carty SE,Hunt JL

更新日期：2006-05-01 00:00:00

abstract：Objectives:To examine the relationship between the recently defined Gleason grade groups and prostate cancer-specific mortality. Methods:If the probability of prostate cancer-specific death is symbolized as P(PSD), the probability of biochemical failure is symbolized as P(BF), and the probability of prostate cancer-sp...

journal_title：American journal of clinical pathology

authors： Vollmer RT

更新日期：2017-03-01 00:00:00

abstract：:The frequency with which blood gas measurements should be obtained is controversial because laboratory-based blood gas analyzers impose blood loss, delay, and cost on each measurement. Point-of-care analyzers eliminate the delay factor, but blood loss and cost factors remain. Optode microsensing can be adopted readily...

journal_title：American journal of clinical pathology

authors： Shapiro BA

更新日期：1995-10-01 00:00:00

abstract：:This study was undertaken to compare several methods of evaluating the common assumption that laboratory data may be treated as if they had been drawn from an underlying Gaussian distribution. As had been described earlier, the usual Kolmogorov-Smirnov test was found to be unsatisfactory due to its sensitivity to roun...

journal_title：American journal of clinical pathology

authors： Rossing RG,Hillis A,Chou DY

更新日期：1985-05-01 00:00:00