Detection of methionine in pernicious anemia megaloblasts and other types of erythroid precursors.

abstract：:Cryostat sections from fully developed papular lesions of lymphomatoid papulosis (histologic subtype A or B) have been examined by immunoenzymatic staining with 24 monoclonal antibodies against lymphoid cells and their subsets. The lesions demonstrated essentially identical cellular compositions and consisted of T-lym...

journal_title：American journal of clinical pathology

authors： Ralfkiaer E,Stein H,Wantzin GL,Thomsen K,Ralfkiaer N,Mason DY

更新日期：1985-11-01 00:00:00

abstract：:The concept of re-engineering rests on computer coordination of information. As a management tool, it has been tested and found to be ambiguous. At best it sharpens laboratory objectives, but at worst it fragments skills and threatens the community attitudes needed for teamwork. Experience with its most fruitful compo...

journal_title：American journal of clinical pathology

authors： Lincoln TL

更新日期：1996-04-01 00:00:00

abstract：:Cellular proliferation is being evaluated as an independent prognostic indicator in a variety of tumors, including non-Hodgkin's lymphomas (NHL). Although the labeling index (LI), using either tritiated thymidine or monoclonal antibodies to bromodeoxyuridine, is considered to be the gold standard of cell kinetic measu...

journal_title：American journal of clinical pathology

authors： Sebo TJ,Roche PC,Witzig TE,Kurtin PJ

更新日期：1993-06-01 00:00:00

abstract：:Primary malignant germ cell tumors of the mediastinum are extremely rare among females. This report describes such a tumor arising in the mediastinum of a 26-year-old woman and correlates immunohistochemical studies of the neoplasm with serum tumor markers. Microscopic examination of the tumor revealed an embryonal ca...

journal_title：American journal of clinical pathology

authors： Sandhaus L,Strom RL,Mukai K

更新日期：1981-04-01 00:00:00

abstract：:A goat anti-serum was prepared against mucinous ovarian cyst fluid and absorbed with normal colon and a variety of normal tissues until the only residual immunoreactivity was directed against colon cancer and ovarian tumor mucin. The set of antigenic determinants defined by this anti-serum has been called COTA, standi...

journal_title：American journal of clinical pathology

authors： Pant KD,Fenoglio-Preiser CM,Berry CO,Zamora PO,Ram MD,Fulks RM,Rhodes BA

更新日期：1986-07-01 00:00:00

abstract：:We retrospectively reviewed the immunophenotypic profile of 75 cases of lymphoplasmacytic lymphoma/Waldenström macroglobulinemia (LPL/WM) analyzed by flow cytometry. All patients had monoclonal IgM (median, 2,100 mg/dL [21 g/L]) in serum and were considered clinically to have WM. The neoplastic cells, in all cases, ex...

journal_title：American journal of clinical pathology

authors： Konoplev S,Medeiros LJ,Bueso-Ramos CE,Jorgensen JL,Lin P

更新日期：2005-09-01 00:00:00

abstract：:A man was hospitalized with bacteremic Achromobacter xylosoxidans type IIIa pneumonia. The authors are aware of no previously reported similar infections caused by this bacterium. A clinical cure was achieved with a combination of carbenicillin and kanamycin therapy. Microtiter susceptibility testing revealed that car...

journal_title：American journal of clinical pathology

authors： Dworzack DL,Murray CM,Hodges GR,Barnes WG

更新日期：1978-10-01 00:00:00

abstract：:The availability of automated anti-Xa heparin assays provides the opportunity to manage patient unfractionated heparin levels directly, rather than by the activated partial thromboplastin time. Because critically ill patients can acquire an antithrombin deficiency, we compared the performance of 3 anti-Xa heparin assa...

journal_title：American journal of clinical pathology

authors： Lehman CM,Rettmann JA,Wilson LW,Markewitz BA

更新日期：2006-09-01 00:00:00

abstract：:A simple assay based on molecular light scattering was developed to detect soluble immune complexes. In this assay the percentage of relative light scattering (%RLS) caused by complexes in buffer containing polyethylene glycol 6000 (PEG) was measured with a laser nephelometer. In low concentrations of PEG (3%-5%), IgG...

journal_title：American journal of clinical pathology

authors： Koethe SM,Melton HE,Jendrzejczak Z

更新日期：1980-12-01 00:00:00

abstract：:Certain new hematologic findings in eight homosexual or bisexual patients with the acquired immune deficiency syndrome (AIDS) are presented. All eight patients manifested a normochromic, normocytic anemia, and six of eight had granulocytopenia during their hospitalization. The other two had low-normal granulocyte coun...

journal_title：American journal of clinical pathology

authors： Schneider DR,Picker LJ

更新日期：1985-08-01 00:00:00

abstract：:Mucocele-like tumors of the breast originally were reported by Rosen in 1986 as benign lesions that histologically resembled colloid carcinoma of the breast. The authors document two cases of mucocele-like tumors to illustrate the difficulty in separating these lesions from colloid carcinoma on the basis of fine-needl...

journal_title：American journal of clinical pathology

authors： Bhargava V,Miller TR,Cohen MB

更新日期：1991-06-01 00:00:00

abstract：:We sought to determine the sensitivity and specificity of immunohistochemistry using the TORDJI-22 MoAb (BioGenex, San Ramon, Calif), which is specific for the C-100 protein of the hepatitis C virus, compared with reverse transcriptase-polymerase chain reaction (RT-PCR) of tissue for viral RNA. RT-PCR had been perform...

journal_title：American journal of clinical pathology

authors： Brody RI,Eng S,Melamed J,Mizrachi H,Schneider RJ,Tobias H,Teperman LW,Theise ND

更新日期：1998-07-01 00:00:00

abstract：:Immunohistochemical analysis, the most efficient way of assaying for HER-2/neu overexpression in patients with invasive breast cancer, is subject to variation in sensitivity and evaluation when used in multiple laboratories. Cell lines with differing but constant levels of HER-2/neu expression have been advocated as s...

journal_title：American journal of clinical pathology

authors： Rhodes A,Borthwick D,Sykes R,Al-Sam S,Paradiso A

更新日期：2004-07-01 00:00:00

abstract：:Plasma biomarker analysis requires intact unbiased starting material. We analyzed the effects on plasma protein profiles of protease inhibitor cocktails and preprocessing storage. Plasma from 12 healthy subjects collected with and without protease inhibitors was prepared immediately and after 2 hours of room temperatu...

journal_title：American journal of clinical pathology

authors： Ayache S,Panelli M,Marincola FM,Stroncek DF

更新日期：2006-08-01 00:00:00

abstract：:A critical limit protocol requiring that all point of care glucose meter readings > 22.2 mmol/L (400 mg/dL) and < 2.2 mmol/L (40 mg/dL) be immediately confirmed by the laboratory was assessed. A total of 193 (2%) of 9,523 glucose meter determinations (63 patients) were > 22.2 or < 2.2 mmol/L. One hundred twenty-two (6...

journal_title：American journal of clinical pathology

authors： Lum G

更新日期：1996-09-01 00:00:00

abstract：:p53 protein expression was evaluated in a series of 204 primary colorectal adenocarcinomas by immunohistochemistry using frozen tissue sections and monoclonal antibody DO-7. Nuclear staining of more than 5% of neoplastic cells was observed in 124 (60.8%) adenocarcinomas, which were classified as p53 positive. p53 immu...

journal_title：American journal of clinical pathology

authors： Lanza G Jr,Maestri I,Dubini A,Gafa R,Santini A,Ferretti S,Cavazzini L

更新日期：1996-05-01 00:00:00

abstract：:Three stillborn fetuses are reported in which an abdominal wall defect was associated with defects in the urogenital and anal region. Autopsy of these fetuses provided clues indicative of how and where the embryonic development went wrong. The malformation involved a disturbance of the cell deposition process, occurri...

journal_title：American journal of clinical pathology

authors： Hartwig NG,Steffelaar JW,Van de Kaa C,Schueler JA,Vermeij-Keers C

更新日期：1991-11-01 00:00:00

abstract：:Double immunostaining of tissue sections by monoclonal antibodies has been performed using, in immunofluorescence, combinations of reagents conjugated with different fluorochromes. These were monoclonal antibodies directly labeled with phycoerythrin (a new red fluorochrome) and haptenated monoclonal antibodies detecte...

journal_title：American journal of clinical pathology

authors： Pizzolo G,Chilosi M

更新日期：1984-07-01 00:00:00

abstract：:The clinical and pathologic features of 64 inflammatory fibroid polyps of the large and small bowel in 63 patients are reported. Six of the lesions in the small bowel were studied by electron microscopy. Follow-up information was obtained from 39 patients. The lesion was always benign, occurred at all ages, and had a ...

journal_title：American journal of clinical pathology

authors： Shimer GR,Helwig EB

更新日期：1984-06-01 00:00:00

abstract：:This study examines the relationship between age and mitogen-induced lymphocyte blastogenesis. Lymphocytes were stimulated with PHA; Concanavalin A (Con A), and PWM in 156 normal, healthy subjects ranging in age from birth to 75 years. The findings indicate a gradual but significant decrease in PHA- and Con A-induced ...

journal_title：American journal of clinical pathology

authors： Hicks MJ,Jones JF,Thies AC,Weigle KA,Minnich LL

更新日期：1983-08-01 00:00:00

abstract：:Intrauterine pulmonary infarction is extremely rare. In a series of 775 stillborn and newborn infants, only a few cases of acute pulmonary infarction were reported. The authors present the findings from a full-term infant who died at 9 hours of age of a chronic pulmonary infarction. Several pathogenic mechanisms, incl...

journal_title：American journal of clinical pathology

authors： Mirkin LD,Wong RC

更新日期：1993-12-01 00:00:00

abstract：:This study focused on women who had an abnormal Papanicolaou smear and a subsequent colposcopic examination negative for a cervical squamous intraepithelial lesion. Cervical swabs obtained during the initial colposcopic examination were analyzed for human papillomavirus (HPV) DNA, and these results were correlated wit...

journal_title：American journal of clinical pathology

authors： Nuovo GJ,Moritz J,Walsh LL,MacConnell P,Koulos J

更新日期：1992-11-01 00:00:00

abstract：:Gastric intraepithelial neoplasia (IEN; formerly dysplasia) is an advanced precancerous lesion. Lesions indefinite for IEN mimic the IEN phenotype but lack some morphologic attributes of IEN. Indefinite for IEN lesions may arise in native foveolae (atypical foveolar hyperproliferation [aFH]) or intestinalized glands (...

journal_title：American journal of clinical pathology

authors： Fassan M,Pizzi M,Farinati F,Nitti D,Zagonel V,Genta RM,Rugge M

更新日期：2012-05-01 00:00:00

abstract：:The greater precision in prothrombin time monitoring obtained using thromboplastins with low international sensitivity index (ISI) values are believed to result in improved patient care. The authors conducted a blinded prospective study of 84 random patients on low-intensity warfarin therapy who were monitored with ei...

journal_title：American journal of clinical pathology

authors： Brophy MT,Fiore LD,Lau J,Goodwin R,Lopez A,Deykin D

更新日期：1994-07-01 00:00:00

abstract：:Terminal transferase (TdT) activity and antigen have been measured in 267 specimens of human bone marrow and peripheral blood by using a biochemical assay for enzymatic activity and an immunofluorescence test for antigen. Oligo p(dA)50 and dGTP were used as reagents in the biochemical assay and either rabbit anti-calf...

journal_title：American journal of clinical pathology

authors： Cibull ML,Coleman MS,Nelson O,Hutton JJ,Gordon D,Bollum FJ

更新日期：1982-04-01 00:00:00

abstract：:The authors report two cases of vernix caseosa peritonitis, an infrequent complication of cesarean section with distinctive histopathologic findings. Both patients underwent exploratory laparotomy for unexplained abdominal pain after cesarean section. Histopathologic evaluation of surgically removed tissue revealed an...

journal_title：American journal of clinical pathology

authors： George E,Leyser S,Zimmer HL,Simonowitz DA,Agress RL,Nordin DD

更新日期：1995-06-01 00:00:00

abstract：:Same-day turnaround of pathology specimens is desirable in this era of managed care, and rapid microwave tissue processing produces histologic features of a quality equivalent to overnight processing. We studied whether microwave-assisted rapid tissue processing adversely affects the quality of immunohistochemical sta...

journal_title：American journal of clinical pathology

authors： Emerson LL,Tripp SR,Baird BC,Layfield LJ,Rohr LR

更新日期：2006-02-01 00:00:00

abstract：:Clq precipitins were assayed in a model system by absorption nephelometry. Polyethylene glycol was used to extract immune complexes so that sufficient sensitivity with minimal interference could be achieved. Using a double beam spectrophotometer, we found that the reaction of immune complexes with Clq occurred rapidly...

journal_title：American journal of clinical pathology

authors： Levinson SS,Goldman J

更新日期：1983-04-01 00:00:00

abstract：OBJECTIVES:Millions of biospecimens will be collected during the coronavirus disease 2019 (COVID-19) pandemic. As learned from severe acute respiratory syndrome (SARS), proper biospecimen handling is necessary to prevent laboratory-related infections. METHODS:Centers for Disease Control and Prevention and World Health...

journal_title：American journal of clinical pathology

authors： Lankes HA,Makhlouf H

更新日期：2021-01-04 00:00:00

abstract：:Examination of urinary sediment has been recommended as a useful diagnostic aid for renal amyloidosis. This procedure was evaluated in the cases of 57 patients, including 11 with proven renal amyloidosis and 13 considered very likely to have the disease. At least three types of urinary fibrillar material were observed...

journal_title：American journal of clinical pathology

authors： Winer RL,Wuerker RB,Erickson JO,Cooper WL

更新日期：1979-01-01 00:00:00