Computer-assisted diagnostic surgical pathology reporting.

abstract：:Marfan syndrome is one of the most common connective tissue diseases and may manifest with a range of symptoms and pathologic changes. We present a retrospective series of 5 cases of patients with Marfan syndrome and pulmonary pathology. Patients were young to middle-aged adults with absent or minimal smoking historie...

journal_title：American journal of clinical pathology

authors： Dyhdalo K,Farver C

更新日期：2011-12-01 00:00:00

abstract：:Hairy cell populations of greater than 90 purity were prepared from six samples obtained from four patients with leukemic reticuloendotheliosis (LRE). These then were analyzed for surface immunoglobulin (SIg) and antigens specified by a panel of monoclonal antibodies. The hairy cells from all patients displayed SIg an...

journal_title：American journal of clinical pathology

authors： Janckila AJ,Stelzer GT,Wallace JH,Yam LT

更新日期：1983-04-01 00:00:00

abstract：:Two commercial enzyme-linked immunosorbent assays (EIAs) for human immunodeficiency virus (HIV) antigens were evaluated for sensitivity and reproducibility by use of supernatant fluid from cell cultures of peripheral mononuclear cells of 18 patients with acquired immunodeficiency syndrome (AIDS) and 12 asymptomatic HI...

journal_title：American journal of clinical pathology

authors： Jackson JB,Sannerud K,Rhame FS,Balfour HH Jr

更新日期：1988-06-01 00:00:00

abstract：:Factor V Leiden (FVR506Q) is a genetic defect in the factor V (FV) molecule that confers resistance to proteolysis by activated protein C (APC) and is the most common abnormality detected in patients studied for hereditary thrombophilia. The initial screening test for this abnormality was a comparison of the activated...

journal_title：American journal of clinical pathology

authors： Akhtar MS,Blair AJ,King TC,Sweeney JD

更新日期：1998-04-01 00:00:00

abstract：:We evaluated a comprehensive deidentification engine at the University of Pittsburgh Medical Center (UPMC), Pittsburgh, PA, that uses a complex set of rules, dictionaries, pattern-matching algorithms, and the Unified Medical Language System to identify and replace identifying text in clinical reports while preserving ...

journal_title：American journal of clinical pathology

authors： Gupta D,Saul M,Gilbertson J

更新日期：2004-02-01 00:00:00

abstract：:The cases of three patients who had clinical courses and hematologic data consistent with plasma-cell leukemia or a terminal leukemic phase of multiple myeloma are presented. A double Bence Jones protein was demonstrated in the urine of two of the patients. Immunoelectrophoresis and immunofluorescence studies demonstr...

journal_title：American journal of clinical pathology

authors： Pedraza MA

更新日期：1975-09-01 00:00:00

abstract：:Colorectal cancer with microsatellite instability (MSI) may occur sporadically or be inherited in cases of hereditary nonpolyposis colorectal cancer (HNPCC) syndrome. However, there is no consensus as to which patients must be tested and how to test MSI. In this study, MSI was tested by immunohistochemical analysis an...

journal_title：American journal of clinical pathology

authors： Bouzourene H,Taminelli L,Chaubert P,Monnerat C,Seelentag W,Sandmeier D,Andrejevic S,Matter M,Bosman F,Benhattar J

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVES:Myeloid and lymphoid neoplasms with abnormalities of fibroblast growth factor receptor 1 gene (FGFR1) are a rare and aggressive disease group that harbors translocations of FGFR1 with at least 14 recognized partner genes. We report a case of a patient with a novel t(17;21)(p13;q22) with RUNX1 rearrangement a...

journal_title：American journal of clinical pathology

authors： Kumar KR,Chen W,Koduru PR,Luu HS

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVES:To identify, describe, and investigate the clinical, radiologic, and pathologic features of 8 cases of telangiectatic oncocytoma. METHODS:Fifty-three consecutive renal oncocytomas were reviewed for the telangiectatic pathologic features that were subsequently correlated with the demographic, clinical, and r...

journal_title：American journal of clinical pathology

authors： Xiao GQ,Ko HB,Unger P

更新日期：2013-07-01 00:00:00

abstract：:Serrated adenomas are the precursors of at least 5.8% of colorectal cancers; otherwise little is known of their clinical significance in comparison with conventional adenomas and hyperplastic polyps. We compared the risk of metachronous lesions in colorectal serrated adenomas, conventional adenomas, and hyperplastic p...

journal_title：American journal of clinical pathology

authors： Lazarus R,Junttila OE,Karttunen TJ,Mäkinen MJ

更新日期：2005-03-01 00:00:00

abstract：Objectives:Approximately 15% of breast cancers show equivocal human epidermal growth factor receptor 2 (HER2) results on HER2 immunohistochemistry (IHC) and are reflexed for fluorescence in situ hybridization (FISH). However, some cases remain equivocal. In this study, we evaluated these double-equivocal cases by using...

journal_title：American journal of clinical pathology

authors： Hou Y,Nitta H,Li Z

更新日期：2017-01-01 00:00:00

abstract：:We compared the grading and staging of transurethral resection of the bladder (TURB) and cystectomy specimens for 105 patients who underwent radical cystectomy for urothelial carcinoma between 1980 and 1984. Of 105 patients, 96% underwent cystectomy within 100 days of TURB (median interval, 10 days). Grading was perfo...

journal_title：American journal of clinical pathology

authors： Cheng L,Neumann RM,Weaver AL,Cheville JC,Leibovich BC,Ramnani DM,Scherer BG,Nehra A,Zincke H,Bostwick DG

更新日期：2000-02-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection may be complicated by non-Hodgkin's lymphoma. We describe eight cases of B-cell extranodal non-Hodgkin's lymphoma occurring during the course of chronic HCV-related hepatic disease (low-grade of mucosa-associated lymphoid tissue [MALT]-type; diffuse large cell; Burkitt; diffuse small ...

journal_title：American journal of clinical pathology

authors： Ascoli V,Lo Coco F,Artini M,Levrero M,Martelli M,Negro F

更新日期：1998-05-01 00:00:00

abstract：:A critical limit protocol requiring that all point of care glucose meter readings > 22.2 mmol/L (400 mg/dL) and < 2.2 mmol/L (40 mg/dL) be immediately confirmed by the laboratory was assessed. A total of 193 (2%) of 9,523 glucose meter determinations (63 patients) were > 22.2 or < 2.2 mmol/L. One hundred twenty-two (6...

journal_title：American journal of clinical pathology

authors： Lum G

更新日期：1996-09-01 00:00:00

abstract：:To determine the diagnostic significance of the kappa/lambda ratio in germinal center (GC) B cells in Hashimoto thyroiditis (HT), we used 4-color flow cytometry to immunophenotype 27 samples (21 patients) of well-characterized HT B-cell clonality was analyzed further by polymerase chain reaction (PCR) of the immunoglo...

journal_title：American journal of clinical pathology

authors： Chen HI,Akpolat I,Mody DR,Lopez-Terrada D,De Leon AP,Luo Y,Jorgensen J,Schwartz MR,Chang CC

更新日期：2006-01-01 00:00:00

abstract：:Although papillary forms of intraductal cancer are a common component of amny mammary cancers, invasive papillary cancer of the breast is relatively rare. Only 35 examples were encountered in the specimens obtained from 1603 women participating in a prospective randomized study of invasive mammary cancer. Contingency-...

journal_title：American journal of clinical pathology

authors： Fisher ER,Palekar AS,Redmond C,Barton B,Fisher B

更新日期：1980-03-01 00:00:00

abstract：OBJECTIVES:Universal screening of upper tract urothelial carcinoma (UTUC) for Lynch syndrome by mismatch repair (MMR) protein immunohistochemistry (IHC) has been recommended by some investigators. Herein, we assess this recommendation retrospectively by simulating its performance on a retrospective, unselected cohort o...

journal_title：American journal of clinical pathology

authors： Gayhart MG,Johnson N,Paul A,Quillin JM,Hampton LJ,Idowu MO,Smith SC

更新日期：2020-11-04 00:00:00

abstract：:Eosinophils are normally absent from the urine. Their presence has been associated with a variety of clinical conditions affecting the kidney or urinary tract. The authors examined the clinical significance and eosinophils, in particular, for acute interstitial nephritis. ...

journal_title：American journal of clinical pathology

authors： Corwin HL,Haber MH

更新日期：1987-10-01 00:00:00

abstract：:We sought to determine whether a group of cases that was relatively high in disagreements and subsequent amendments could be identified and targeted for blinded review. During a 4-year period, 8,916 surgical pathology and nongynecologic cytology cases were subjected to blinded review; of these, there were 616 disagree...

journal_title：American journal of clinical pathology

authors： Renshaw AA,Gould EW

更新日期：2006-11-01 00:00:00

abstract：:The presence of antineutrophil cytoplasmic autoantibodies with specificity for proteinase 3 (PR3-ANCA) usually is detected by enzyme-linked immunosorbent assay (ELISA) with purified PR3 as a substrate. We studied the technical performance of direct and capture ELISA using a recombinant proteolytically inactive form of...

journal_title：American journal of clinical pathology

authors： Rarok AA,Huitema MG,van der Leij MJ,van der Geld YM,Berthold H,Schmitt J,Stegeman CA,Limburg PC,Kallenberg CG

更新日期：2003-10-01 00:00:00

abstract：:p53 protein expression was evaluated in a series of 204 primary colorectal adenocarcinomas by immunohistochemistry using frozen tissue sections and monoclonal antibody DO-7. Nuclear staining of more than 5% of neoplastic cells was observed in 124 (60.8%) adenocarcinomas, which were classified as p53 positive. p53 immu...

journal_title：American journal of clinical pathology

authors： Lanza G Jr,Maestri I,Dubini A,Gafa R,Santini A,Ferretti S,Cavazzini L

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVES:To support our Lean culture of continuous improvement, we implemented a daily management system designed so critical metrics of operational success were the focus of local teams to drive improvements. METHODS:We innovated a standardized visual daily management board composed of metric categories of Quality,...

journal_title：American journal of clinical pathology

authors： Zarbo RJ,Varney RC,Copeland JR,D'Angelo R,Sharma G

更新日期：2015-07-01 00:00:00

abstract：:Two monoclonal antibodies, UCD/AB 6.11 and UCD/PR 10.11, were evaluated for their patterns of immunohistochemical reactivity in a survey of paraffin-embedded human tissues by the avidin-biotin-immunoperoxidase technique. By two-dimensional immunoblotting, UCD/AB 6.11 reacts with keratin number 18 and UCD/PR 10.11 iden...

journal_title：American journal of clinical pathology

authors： Chan R,Edwards BF,Hu R,Rossitto PV,Min BH,Lund JK,Cardiff RD

更新日期：1988-04-01 00:00:00

abstract：:Posttransplantation lymphoproliferative disorders (PT-LPDs) occurring in T-cell depleted (TCD) allogeneic bone marrow transplant recipients seem to be different from those that arise in solid organ recipients in their early development, the high incidence of extensive dissemination at presentation, and their aggressiv...

journal_title：American journal of clinical pathology

authors： Orazi A,Hromas RA,Neiman RS,Greiner TC,Lee CH,Rubin L,Haskins S,Heerema NA,Gharpure V,Abonour R,Srour EF,Cornetta K

更新日期：1997-04-01 00:00:00

abstract：:With various methods, BRAF mutations have been detected in 73.4% to 87.1% of papillary thyroid carcinomas (PTCs) in Korea. We assessed the ability of allele-specific polymerase chain reaction using a dual priming oligonucleotide system, compared with direct sequencing and pyrosequencing, to detect BRAF mutations in fi...

journal_title：American journal of clinical pathology

authors： Lee HJ,Choi J,Hwang TS,Shong YK,Hong SJ,Gong G

更新日期：2010-05-01 00:00:00

abstract：:Sex cord tumor with annular tubules (SCTAT) is a distinctive ovarian sex cord-stromal tumor. The authors describe a case of SCTAT arising outside the ovaries, in the fallopian tube. The authors are aware of only one other case of extra-ovarian SCTAT, in an umbilical hernia sac in an adult woman. The case reported was ...

journal_title：American journal of clinical pathology

authors： Griffith LM,Carcangiu ML

更新日期：1991-08-01 00:00:00

abstract：:The diagnosis of myeloid leukemia cutis can be difficult, particularly in the context of an initial skin biopsy with a malignant hematopoietic neoplasm. We studied the immunohistochemical characteristics of 33 cases of myeloid leukemia cutis diagnosed at Stanford University Medical Center, Stanford, CA, 1996-2007, and...

journal_title：American journal of clinical pathology

authors： Cronin DM,George TI,Sundram UN

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVES:This study examines whether the assumptions that pathologists understand the medical malpractice negligence rule and have a clear single standard of care are reasonable. METHODS:Two hundred eighty-one Texas academic pathologists and trainees were presented 10 actual pathology malpractice cases from publicly...

journal_title：American journal of clinical pathology

authors： Allen TC,Stafford M,Liang BA

更新日期：2014-04-01 00:00:00

abstract：:Fine-needle aspiration (FNA) of thyroid bed (TB) lesions is a common diagnostic modality in monitoring patients for recurrent cancer after a thyroidectomy. To elucidate the value of TB FNA, we reviewed our experience at The Johns Hopkins Hospital, Baltimore, MD. We identified 57 TB FNA specimens from 50 patients. Of t...

journal_title：American journal of clinical pathology

authors： Bishop JA,Owens CL,Shum CH,Ali SZ

更新日期：2010-08-01 00:00:00

abstract：:Inhibition of anti-Rh29 by erythrocytic stroma in feces was devised as a specific test for fecal occult blood. The sensitivity of this test was equivalent to that of a standard Hemoccult test, namely, 10(8) erythrocytes/g feces. Comparison of results of this test with results of Hemoccult tests of random stool specime...

journal_title：American journal of clinical pathology

authors： Rosenfield RE,Kochwa S,Kaczera Z,Maimon J

更新日期：1979-02-01 00:00:00