bcl-2 expression by multicolor flow cytometric analysis assists in the diagnosis of follicular lymphoma in lymph node and bone marrow.

abstract：OBJECTIVES:Edoxaban, an oral direct factor Xa inhibitor, does not require routine monitoring. However, assessment of the anticoagulant effects may be required in certain situations. METHODS:We investigated the effects of edoxaban on prothrombin time (PT), activated partial thromboplastin time (aPTT), and thrombin gene...

journal_title：American journal of clinical pathology

authors： Morishima Y,Kamisato C

更新日期：2015-02-01 00:00:00

abstract：:The authors studied the performance of four measures of laboratory turnaround time: the mean, median, 90th percentile, and proportion of tests reported within a predetermined cut-off interval (proportion of acceptable tests [PAT]). Measures were examined with the use of turnaround time data from 11,070 stat partial th...

journal_title：American journal of clinical pathology

authors： Valenstein PN,Emancipator K

更新日期：1989-04-01 00:00:00

abstract：:Staphylococcus epidermidis is among the most common organisms isolated from blood cultures. Conversely, it is rarely a well-documented cause of natural-valve endocarditis. However, several authors have reported series of patients with the clinical picture of endocarditis and S. epidermidis bacteremia. Most of these ca...

journal_title：American journal of clinical pathology

authors： Littenberg B,Cooper B,Levitz R

更新日期：1987-03-01 00:00:00

abstract：:There are few studies that examine prevalence, quantity, and cellular proclivity of latent human herpesvirus 6 (HHV-6) in healthy populations. We examined 69 tonsils with paired blood specimens from children without evidence of acute infection. By polymerase chain reaction (PCR), HHV-6 was detected at low levels in 10...

journal_title：American journal of clinical pathology

authors： Roush KS,Domiati-Saad RK,Margraf LR,Krisher K,Scheuermann RH,Rogers BB,Dawson DB

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVES:High-grade serous carcinoma (HGSC) is the most common ovarian malignancy. The role of cytopathology in obtaining tissue diagnosis before institution of neoadjuvant chemotherapy (NACT) was evaluated. METHODS:All histopathology-proven HGSC specimens between 2015 and 2018 with prior cytopathologic diagnosis by...

journal_title：American journal of clinical pathology

authors： Bansal A,Srinivasan R,Rohilla M,Sundaram A,Rai B,Rajwanshi A,Suri V,Saha SC,Gupta N,Gupta P,Dey P

更新日期：2020-06-08 00:00:00

abstract：:An antithrombin assay (AA) and an antithrombin assay modified by the addition of heparin (H-AA) were performed using sera from healthy subjects, patients predisposed to thrombosis, and patients with thromboembolic disease. Characteristic AA, and H-AA patterns were found in each group. Normal controls and four of 39 "p...

journal_title：American journal of clinical pathology

authors： Innerfield I,Stone ML,Mersheimer W,Clauss RD,Greenberg J

更新日期：1976-03-01 00:00:00

abstract：:The radioimmunoassay of ACTH was used in a routine laboratory to localize the site of the lesion in 20 patients with Cushing's syndrome. Eight of the patients had no detectable circulating ACTH and had adrenal tumors removed, 12 had high levels and were diagnosed as having pituitary Cushing's syndrome. Very high level...

journal_title：American journal of clinical pathology

authors： Broughton A

更新日期：1975-11-01 00:00:00

abstract：:We describe 13 cases in which the submucosa and muscularis mucosae of the gastrointestinal tract exhibited a focal or diffuse increase of elastin fibers. This elastosis or elastofibromatous change most commonly manifested as a colonic polyp and usually was found during screening colonoscopy. Gastric and small intestin...

journal_title：American journal of clinical pathology

authors： Hobbs CM,Burch DM,Sobin LH

更新日期：2004-08-01 00:00:00

abstract：:A comparative evaluation of two commercial kits that detect antinuclear antibodies via indirect immunofluorescence was undertaken using an adult ambulatory population. The sensitivity and specificity of the kits were compared to determine which of the two was more efficient as a screening test for systemic lupus eryth...

journal_title：American journal of clinical pathology

authors： Valdiserri RO,Petronie JS

更新日期：1984-03-01 00:00:00

abstract：:The recent clinical and commercial success of anticancer antibodies such as rituximab and trastuzumab has created great interest in antibody-based therapeutics for hematopoietic malignant neoplasms and solid tumors. Given the likelihood of lower toxic effects of antibodies that target tumor cells and have limited impa...

journal_title：American journal of clinical pathology

authors： Ross JS,Gray K,Gray GS,Worland PJ,Rolfe M

更新日期：2003-04-01 00:00:00

abstract：:Nuclear DNA content of 20 cases of primary differentiated thyroid carcinoma, 27 corresponding cervical lymph node metastases, and 2 local recurrent tumors was determined by flow cytometry. Evidence of DNA aneuploidy was found in either the primary tumor or in the corresponding metastases in 10 (63%) of the 16 papillar...

journal_title：American journal of clinical pathology

authors： Joensuu H,Klemi PJ

更新日期：1988-01-01 00:00:00

abstract：:Experiences of the CAP Survey Program in reticulocyte counts and morphologic identification of reticulocytes from 1971 to 1974 are reviewed. Problems of morphologic identification are reflected in an excessive variance of reticulocyte counts. Statistical sources of variations in counting are identified. The older, ori...

journal_title：American journal of clinical pathology

authors： Gilmer PR Jr,Koepke JA

更新日期：1976-07-01 00:00:00

abstract：:Worldwide, infection with hepatitis viruses remains a major clinical and public heath concern. The laboratory is an integral part of the diagnosis of these infections since many of the manifestations are nonspecific, and the various hepatitis viruses show overlapping symptomatology. In this article, we discuss the lab...

journal_title：American journal of clinical pathology

authors： Harris KR,Dighe AS

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVES:To investigate the clinicopathologic features of extranodal natural killer/T-cell lymphoma (ENKTL) not preceded by another Epstein-Barr virus (EBV)-related disorder in children and adolescents. METHODS:A series of 17 cases of ENKTL not preceded by another EBV-related disorder in children and adolescents in ...

journal_title：American journal of clinical pathology

authors： Huang Y,Xie J,Ding Y,Zhou X

更新日期：2016-01-01 00:00:00

abstract：:Carumonam, a new monobactam, was found to have an anti-microbial spectrum similar to aztreonam. Its spectrum includes Enterobacteriaceae, Haemophilus influenzae, pathogenic Neisseria species, Pseudomonas aeruginosa, and some streptococci. Staphylococcus species, enterococci, and many other nonenteric gram-negative bac...

journal_title：American journal of clinical pathology

authors： Jones RN,Barry AL,Thornsberry C,Fuchs PC,Packer RR

更新日期：1986-11-01 00:00:00

abstract：:Lesions of the breast containing extravasated mucin span a continuum from benign mucoceles to invasive mucinous (colloid) carcinoma. It is well known that distinguishing benign from malignant mucinous lesions is difficult infine-needle aspiration material. Whether these lesions also are difficult to distinguish in cor...

journal_title：American journal of clinical pathology

authors： Renshaw AA

更新日期：2002-07-01 00:00:00

abstract：:The cytologic features of fine-needle aspiration specimens from 16 breast carcinomas that closely simulated benign lesions were analyzed and compared to smears from fibroadenomas and fibrocystic change. No combination of features was found that accurately separated all benign and malignant cases. Many nuclei with disc...

journal_title：American journal of clinical pathology

authors： Rogers LA,Lee KR

更新日期：1992-08-01 00:00:00

abstract：:The immunohistologic distribution of the feto-acinar pancreatic protein (FAP), detected by the monoclonal antibody (MoAb) J28 using an indirect immunoperoxidase technique, is described. Tests were carried out on normal adult pancreas (n = 10), chronic pancreatitis (n = 14), pancreatic adenocarcinoma (n = 17), intraabd...

journal_title：American journal of clinical pathology

authors： Albers GH,Escribano MJ,Daher N,Nap M

更新日期：1990-01-01 00:00:00

abstract：:Forty-three laboratories participated in an interlaboratory testing program offered by the College of American Pathologists for the radioimmunoassay (RIA) of carcinoembryonic antigen (CEA). Thirty correctly reported a sample with 1.9 ng of endogenous CEA per ml as less than 2.5 ng. For samples with added exogenous CEA...

journal_title：American journal of clinical pathology

authors： Reynoso G,Keane M,Konopka S

更新日期：1977-07-01 00:00:00

abstract：:Previous studies have found that amplification and overexpression of the c-erbB-2 oncogene in mammary ductal adenocarcinomas predicts decreased disease-free or overall survival. Information regarding the prognostic and pathogenetic significance of oncogene amplification has been limited by difficulty obtaining suffici...

journal_title：American journal of clinical pathology

authors： Gramlich TL,Cohen C,Fritsch C,DeRose PB,Gansler T

更新日期：1994-04-01 00:00:00

abstract：:The development of a precise, mathematical relationship between blood pressure and renal microvascular abnormalities would be highly desirable. Such a relationship would require that abnormalities be quantitative on a rational scale. The dominant abnormality in nephrosclerosis occurs in arcuate and cortical arteries o...

journal_title：American journal of clinical pathology

authors： Tracy RE,Mercante DE,Moncada A,Berenson G

更新日期：1986-03-01 00:00:00

abstract：:The authors investigated the stability of the tests comprising the SMA-6 and SMA-12 chemistry profiles during overnight refrigerated storage. Several constituents were found to undergo changes that were statistically significant when evaluated by a t test for paired comparisons. A recently published sequential method ...

journal_title：American journal of clinical pathology

authors： Rossing RG,Foster DM

更新日期：1980-01-01 00:00:00

abstract：:DNA sequencing was used to confirm Chlamydia trachomatis and Neisseria gonorrhoeae nucleic acids in endocervical swab samples. DNA in residues of the samples with positive results by 2 commercial kits was subjected to nested polymerase chain reaction (PCR) amplification. The nested PCR amplicons were used as templates...

journal_title：American journal of clinical pathology

authors： Lee SH,Vigliotti VS,Pappu S

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:We describe the morphologic and immunohistochemical features of 17 endometrial stromal neoplasms, 16 sarcomas, and one stromal nodule. METHODS:We reviewed 35 cases interpreted as endometrial stromal neoplasms, but 17 high-grade endometrial stromal sarcomas (ESS) and one case of mixed endometrial sarcoma and...

journal_title：American journal of clinical pathology

authors： Albores-Saavedra J,Dorantes-Heredia R,Chablé-Montero F,Chanona-Vilchis J,Pérez-Montiel D,Lino-Silva LS,González-Romo MA,Ramírez-Jaramillo JM,Henson DE

更新日期：2014-06-01 00:00:00

abstract：:A case of florid proliferative sialometaplasia arising in salivary ductal inclusions in an intraparotid lymph node is described. This lesion probably represents an exuberant response to sialadenitis. Other entities that enter into its differential diagnosis in this particular location are discussed. Except for Warthin...

journal_title：American journal of clinical pathology

authors： Goldman RL,Klein HZ

更新日期：1986-07-01 00:00:00

abstract：:Poor core laboratory performance that causes delays in diagnosis and treatment is an impediment to optimal patient care, particularly in high-volume patient care areas such as the emergency department (ED). To evaluate the impact of laboratory performance on patient care outcomes, we obtained data from 11 hospitals re...

journal_title：American journal of clinical pathology

authors： Holland LL,Smith LL,Blick KE

更新日期：2005-11-01 00:00:00

abstract：:Cellular and humoral immunity combine to determine the outcome following exposure to hepatitis virus and are implicated in the proposed pathogenetic mechanism for acute and chronic hepatitis. Although antibody to HBsAg is found in virtually all following recovery from hepatitis B, a cell-mediated response to HBsAg can...

journal_title：American journal of clinical pathology

authors： Lee WM

更新日期：1976-05-01 00:00:00

abstract：:Increasingly, all automated blood counts are not accompanied by a microscopic white blood cell differential. A popular strategy is to obtain a manual differential if any part of the automated blood count and differential is outside specified limits (the "diff-if" strategy). The authors compared two sets of criteria to...

journal_title：American journal of clinical pathology

authors： McClure S,Bates JE,Harrison R,Gilmer PR,Bessman JD

更新日期：1988-08-01 00:00:00

abstract：:Bronchoalveolar lavage (BAL) is a minimally invasive method possibly representing a diagnostic tool in the evaluation of interstitial lung diseases (ILDs) of different causes. We first describe herein the morphologic, histochemical, and immunohistochemical features of previously unreported eosinophilic globular deposi...

journal_title：American journal of clinical pathology

authors： Rossi G,Andreani A,Morandi P,Marchioni A,Corradini P,Cappiello G,Bortolotti M,Qosja A,Manzini C,Ferri C,Richeldi L,Cavazza A

更新日期：2008-12-01 00:00:00

abstract：:Hairy cell populations of greater than 90 purity were prepared from six samples obtained from four patients with leukemic reticuloendotheliosis (LRE). These then were analyzed for surface immunoglobulin (SIg) and antigens specified by a panel of monoclonal antibodies. The hairy cells from all patients displayed SIg an...

journal_title：American journal of clinical pathology

authors： Janckila AJ,Stelzer GT,Wallace JH,Yam LT

更新日期：1983-04-01 00:00:00