Usefulness of DNA ploidy measurement on liquid-based smears showing conflicting results between cytology and high-risk human papillomavirus typing.

abstract：:Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors characterized by mutations of KIT or PDGFRA. The objectives of this study were to evaluate BRAF mutations in GISTs and then to correlate BRAF mutational status in the tumor with clinical parameters, with B-raf expression, and with activation of some cellul...

journal_title：American journal of clinical pathology

authors： Hostein I,Faur N,Primois C,Boury F,Denard J,Emile JF,Bringuier PP,Scoazec JY,Coindre JM

更新日期：2010-01-01 00:00:00

abstract：:CD45/side scatter (SS) gating is widely used for isolating blasts by flow cytometry (FC). However, other cells contaminate the "blast gate" (BG); CD45/SS gating is thus imprecise, particularly when there are few blasts. We studied the BG contents in 21 myelodysplastic syndromes (MDSs), 14 myeloproliferative neoplasms ...

journal_title：American journal of clinical pathology

authors： Harrington AM,Olteanu H,Kroft SH

更新日期：2012-05-01 00:00:00

abstract：:Chicken pox, although common, is rarely associated with autoimmune hemolytic anemia. Reported here is the case of an 8-year-old boy who was found to have cold agglutinin disease and severe anemia several days after he contracted chicken pox. The cold agglutinin appeared to be a polyclonal immunoglobulin M antibody wit...

journal_title：American journal of clinical pathology

authors： Friedman HD,Dracker RA

更新日期：1992-01-01 00:00:00

abstract：:A 26-year-old woman who had undergone orthotopic heart transplantation because of dilative cardiomyopathy received a triple-drug immunosuppressive regimen (cyclosporine A, azathioprine, and prednisolone). During her relatively frequent episodes of acute rejection, she was treated with methylprednisolone and repeated a...

journal_title：American journal of clinical pathology

authors： Kemnitz J,Cremer J,Gebel M,Uysal A,Haverich A,Georgii A

更新日期：1990-07-01 00:00:00

abstract：:Immunoperoxidase strains for prostate-specific antigen (PSA), prostatic acid phosphatase (PAcP), epithelial membrane antigen (EMA), and cytokeratins (MAK 6 and CK-KES) were performed on 1 case of squamous cell carcinoma of the prostate and on 13 cases of squamous metaplasia of prostatic epithelium in an effort to demo...

journal_title：American journal of clinical pathology

authors： Lager DJ,Goeken JA,Kemp JD,Robinson RA

更新日期：1988-11-01 00:00:00

abstract：:Immunohistochemical expression of napsin A in primary pulmonary mucinous tumors is not well established. Napsin A immunoreactivity was evaluated in 43 mucin-producing adenocarcinomas of the lung consisting of 18 tumors formerly classified as mucinous bronchioloalveolar carcinoma, 15 colloid adenocarcinomas, 5 solid pr...

journal_title：American journal of clinical pathology

authors： Wu J,Chu PG,Jiang Z,Lau SK

更新日期：2013-02-01 00:00:00

abstract：:We retrospectively reviewed the immunophenotypic profile of 75 cases of lymphoplasmacytic lymphoma/Waldenström macroglobulinemia (LPL/WM) analyzed by flow cytometry. All patients had monoclonal IgM (median, 2,100 mg/dL [21 g/L]) in serum and were considered clinically to have WM. The neoplastic cells, in all cases, ex...

journal_title：American journal of clinical pathology

authors： Konoplev S,Medeiros LJ,Bueso-Ramos CE,Jorgensen JL,Lin P

更新日期：2005-09-01 00:00:00

abstract：:We reviewed the cytologic features of 20 adrenal cortical carcinomas (ACCs; 9 primary and 11 metastatic) from 19 patients and highlighted diagnostic pitfalls. The mean size of primary ACCs was 11.9 cm, and that of metastatic ACCs was 3.0 cm. The metastatic sites were liver, lung, lymph node, soft tissue, and bone. Pri...

journal_title：American journal of clinical pathology

authors： Ren R,Guo M,Sneige N,Moran CA,Gong Y

更新日期：2006-09-01 00:00:00

abstract：:In the absence of clinical signs, elevated values of the cardiac isoforms of troponin T (cTnT) and I (cTnI) can be found in the serum samples of some patients with skeletal muscle myopathies; the cause is unclear. We studied the messenger RNA (mRNA) expression of cTnT and cTnI in the skeletal muscles of 24 patients wi...

journal_title：American journal of clinical pathology

authors： Messner B,Baum H,Fischer P,Quasthoff S,Neumeier D

更新日期：2000-10-01 00:00:00

abstract：:The results of a direct anaerobic susceptibility testing method were compared with those of a standardized method. Seventy-three blood culture isolates and eight antimicrobial agents were used. The results of the direct and standardized testing methods were within one two-fold dilution for 95.2% of the 584 anaerobe-an...

journal_title：American journal of clinical pathology

authors： Murray PR,Christman JL

更新日期：1980-04-01 00:00:00

abstract：:Hyperparathyroidism may occasionally present as a neck mass resulting from cystic change in a parathyroid adenoma. We report an unusual instance of hyperparathyroidism presenting as a palpable, but asymptomatic hyperplastic parathyroid gland cyst. We conclude that hyperplastic parathyroid glands may undergo cystic deg...

journal_title：American journal of clinical pathology

authors： Fallon MD,Haines JW,Teitelbaum SL

更新日期：1982-01-01 00:00:00

abstract：:A case of a patient with otherwise typical multiple myeloma whose myeloma cells were phagocytic is described. Phagocytosis of erythrocytes, erythrocytic precursors, lymphocytes, and platelets was found. Ingestion of latex particles by myeloma cells was demonstrated in vitro. ...

journal_title：American journal of clinical pathology

authors： Fitchen JH,Lee S

更新日期：1979-06-01 00:00:00

abstract：:We studied the histologic and multiparameter flow cytometry (MFC) features of 12 cases of angioimmunoblastic T-cell lymphoma (AITL), 13 of mature T-cell lymphoma, and 25 control cases of reactive lymphoid hyperplasia to evaluate the role of CD10 in the differential diagnosis of peripheral T-cell lymphomas (PTCLs). A c...

journal_title：American journal of clinical pathology

authors： Stacchini A,Demurtas A,Aliberti S,Francia di Celle P,Godio L,Palestro G,Novero D

更新日期：2007-11-01 00:00:00

abstract：:A method combining alizarin red and a modified silver stain for reticulum fibers in tissue sections is described. The method allows precise localization of calcium deposits and crystals in relation to epithelial and interstitial connective tissue elements. The deposits and their spatial relationships are clearly disce...

journal_title：American journal of clinical pathology

authors： Elbadawi A,Musto LA,Lilien OM

更新日期：1981-03-01 00:00:00

abstract：OBJECTIVES:To support our Lean culture of continuous improvement, we implemented a daily management system designed so critical metrics of operational success were the focus of local teams to drive improvements. METHODS:We innovated a standardized visual daily management board composed of metric categories of Quality,...

journal_title：American journal of clinical pathology

authors： Zarbo RJ,Varney RC,Copeland JR,D'Angelo R,Sharma G

更新日期：2015-07-01 00:00:00

abstract：:The Department of Laboratory Medicine, University of Washington, has explored various management of organizational approaches over the past seven years. The Centralized Processing Area supported by a computerized information system has evolved from these efforts. Despite a decrease in U.W. hospital usage since 1968-69...

journal_title：American journal of clinical pathology

authors： Nussbaum B,Minckler T,Roby R,Ackerman E

更新日期：1977-02-01 00:00:00

abstract：:Fluorescence in situ hybridization (FISH) and immunohistochemical analysis for assessment of HER-2 status in breast carcinomas are discordant in a significant proportion of cases with equivocal (2+) immunostaining. To evaluate the role of intratumoral heterogeneity and degree of amplification, we performed additional ...

journal_title：American journal of clinical pathology

authors： Lewis JT,Ketterling RP,Halling KC,Reynolds C,Jenkins RB,Visscher DW

更新日期：2005-08-01 00:00:00

abstract：:The aim of this study was to evaluate the histopathologic features and the expression of angiogenesis-related markers in primary tumors and metastatic lymph nodes of oral squamous cell carcinomas (SCCs) with multiple lymph node involvement in comparison with oral SCCs without nodal metastasis. The protein levels of th...

journal_title：American journal of clinical pathology

authors： Nikitakis NG,Rivera H,Lopes MA,Siavash H,Reynolds MA,Ord RA,Sauk JJ

更新日期：2003-04-01 00:00:00

abstract：:Southern blot (Oncor, Gaithersburg, MD) and dot blot (Life Technologies, Gaithersburg, MD) nucleic acid hybridization assays were compared for their ability to detect and type human papillomavirus (HPV) DNA in 50 cervical swab specimens and 11 biopsy specimens. Overall agreement between the two methods was 78.7%. With...

journal_title：American journal of clinical pathology

authors： Bartholoma NY,Adelson MD,Forbes BA

更新日期：1991-01-01 00:00:00

abstract：:A simple method designed to allow coagulation studies in heparinized blood was evaluated. Citrated plasma containing heparin was incubated with an anion-exchange resin commercially available in tablet form (Heparsorb). After centrifugation of the mixture, coagulation studies were carried out on the supernatant plasma....

journal_title：American journal of clinical pathology

authors： Cowan JF,Khan MB,Vargo J,Joist JH

更新日期：1981-01-01 00:00:00

abstract：:Cytologic features of the cell-stroma interface are useful in distinguishing between monomorphic adenomas of the basal cell type and adenoid cystic carcinoma. In basal cell adenomas, the collagenous stroma interdigitates with adjacent cells, whereas in adenoid cystic carcinoma, the two are separated by a sharp smooth ...

journal_title：American journal of clinical pathology

authors： Stanley MW,Horwitz CA,Rollins SD,Powers CN,Bardales RH,Korourain S,Stern SJ

更新日期：1996-07-01 00:00:00

abstract：:A goat anti-serum was prepared against mucinous ovarian cyst fluid and absorbed with normal colon and a variety of normal tissues until the only residual immunoreactivity was directed against colon cancer and ovarian tumor mucin. The set of antigenic determinants defined by this anti-serum has been called COTA, standi...

journal_title：American journal of clinical pathology

authors： Pant KD,Fenoglio-Preiser CM,Berry CO,Zamora PO,Ram MD,Fulks RM,Rhodes BA

更新日期：1986-07-01 00:00:00

abstract：:In situ hybridization for the Y chromosome (Y-ISH) was used to identify residual host cells in the peripheral blood of 51 recipients of sex-mismatched allogeneic marrow not depleted of T cells following conditioning with high-dose cyclophosphamide and total body irradiation (TBI). One patient who rejected the graft sh...

journal_title：American journal of clinical pathology

authors： Przepiorka D,Thomas ED,Durnam DM,Fisher L

更新日期：1991-02-01 00:00:00

abstract：:A column chromatographic method for the simultaneous single-eluate isolation of CPK-MB and LDH 1,2 has been evaluated. The method is rapid in that the entire isolation is completed in less than an hour and subsequent analysis can be performed using presently available spectrophotometric methods and reagents without th...

journal_title：American journal of clinical pathology

authors： Lederer WH,Gerstbrein HL,McClintock WC

更新日期：1976-08-01 00:00:00

abstract：:Reference values for hematologic parameters are determined using data from patient populations of a whole year. As a consequence, the authors are not dependent on a limited selected population and can determine reference values for all age and sex groups. It turns out that from the possible compilation technics the ga...

journal_title：American journal of clinical pathology

authors： Swaanenburg JC,Rutten WP,Holdrinet AC,van Strik R

更新日期：1987-08-01 00:00:00

abstract：:The presence of small gas bubbles in devices used to collect blood gas samples is considered. A gas bubble whose relative volume is 0.5 to 1% or more that of the liquid in the collection device is a potential source of significant error. Relationships describing the possible magnitude of this error are derived and sub...

journal_title：American journal of clinical pathology

authors： Mueller RG,Lang GE,Beam JM

更新日期：1976-02-01 00:00:00

abstract：:Monoclonal antibody (MoAb) 44-3A6 recognizes a glandular differentiation-associated antigen and has been used to identify exocrine differentiation in pulmonary carcinomas. The authors assessed its value in the diagnosis of lung carcinomas metastatic to lung/pleura and pleural malignant mesothelioma (MM), using cell bl...

journal_title：American journal of clinical pathology

authors： Spagnolo DV,Whitaker D,Carrello S,Radosevich JA,Rosen ST,Gould VE

更新日期：1991-03-01 00:00:00

abstract：:Labor use ratings assigned to instruments by the Workload Recording Method (WRM) do not change with batch size or walk-away time use. The authors evaluated the effect of both on the labor use of the analyzers Paramax B6100 (Baxter Paramax, Irvine, CA) and Ektachem 700 (Eastman Kodak, Rochester, NY) by timing all worke...

journal_title：American journal of clinical pathology

authors： McClellan GA,Nipper HC,Horn MJ,Burris WD,Hodges K,Monaco S,Cox RS Jr

更新日期：1991-05-01 00:00:00

abstract：:Two commercial enzyme-linked immunosorbent assays (EIAs) for human immunodeficiency virus (HIV) antigens were evaluated for sensitivity and reproducibility by use of supernatant fluid from cell cultures of peripheral mononuclear cells of 18 patients with acquired immunodeficiency syndrome (AIDS) and 12 asymptomatic HI...

journal_title：American journal of clinical pathology

authors： Jackson JB,Sannerud K,Rhame FS,Balfour HH Jr

更新日期：1988-06-01 00:00:00

abstract：:Blood glucose results for 2,601 specimens obtained at multiphasic health examination, divided into three age groups, were analyzed using probability plot paper. Two straight lines could be fitted to each distribution. The assumption was made that the lower lines correspond to "normal-healthy" persons, whereas the uppe...

journal_title：American journal of clinical pathology

authors： Morgenstern NL,Shearn MA

更新日期：1981-08-01 00:00:00