The use of monoclonal antibody 44-3A6 in cell blocks in the diagnosis of lung carcinoma, carcinomas metastatic to lung and pleura, and pleural malignant mesothelioma.

abstract：:Three cases of pulmonary squamous cell carcinoma (SCC) are described displaying a prominent microcystic pattern closely resembling microcystic adnexal carcinoma of the skin (MAC). The patients were 2 women and 1 man aged 72 to 83 years. Histologically, in addition to conventional SCC, all tumors showed striking microc...

journal_title：American journal of clinical pathology

authors： Weissferdt A,Moran CA

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVES:To evaluate the clinical utility of and demand for the creatine kinase (CK)-MB assay. METHODS:We examined the number of CK-MB tests from 2007 through 2013 while we progressively deemphasized their use. We first removed CK-MB from the acute coronary syndrome (ACS) panel and then from the main menu and observ...

journal_title：American journal of clinical pathology

authors： Singh G,Baweja PS

更新日期：2014-03-01 00:00:00

abstract：:The ABH blood group isoantigen status of a retrospective series of 233 invasive breast carcinomas was examined, employing monoclonal antibodies (MCAB) against A, B, and H antigens with the avidin-biotin-peroxidase complex method. In addition, the H antigen was localized with Ulex Europeus Agglutinin I (UEAI) binding. ...

journal_title：American journal of clinical pathology

authors： Lee AK,DeLellis RA,Rosen PP,Saigo PE,Gangi MD,Bagin R,Groshen S,Wolfe HJ

更新日期：1985-03-01 00:00:00

abstract：:Cultures from the gallbladder and blood of a 60-year-old man with acute cholecystitis grew Haemophilus aphrophilus. This organism, an unusual isolate in clinical specimens, is most frequently seen in patients with either endocarditis or brain abscesses. Haemophilus aphrophilus may be distinguished from Eikenella corro...

journal_title：American journal of clinical pathology

authors： Huck W,Britt MR

更新日期：1978-03-01 00:00:00

abstract：OBJECTIVES:The coronavirus disease 2019 pandemic has halted in-person medical student education in many large academic centers, including the University of Washington. We identified a unique opportunity to bring comprehensive and targeted anatomic pathology training to large numbers of medical students who would not re...

journal_title：American journal of clinical pathology

authors： Parker EU,Chang O,Koch L

更新日期：2020-10-13 00:00:00

abstract：:This article describes the occurrence of a coenurus, the encysted larval stage of a cestode of the genus Multiceps, within the axilla of a 40-year-old Nigerian woman. The patient had a history of intraductal carcinoma of the breast two years prior to the finding of an ipsilateral axillary mass. Pathologic evaluation o...

journal_title：American journal of clinical pathology

authors： Kurtycz DF,Alt B,Mack E

更新日期：1983-11-01 00:00:00

abstract：:The platelet aggregation responses induced by adenosine diphosphate (ADP) and collagen were characterized by parameters defining rate and extent of reaction. Values were compared on the basis of platelet concentration, time elapsed between sample collection and test performance, and sex of donors. Rate and extent of a...

journal_title：American journal of clinical pathology

authors： Roper P,Drewinko B,Hasler D,Johnston D,Hester J,Freireich EJ

更新日期：1979-03-01 00:00:00

abstract：:The prehospital environment has not been studied for point-of-care testing. Therefore, the authors' helicopter program evaluated the performance of the i-STAT Portable Clinical Analyzer, a rapid point-of-care, hand-held instrument. The primary aim of the study was to determine if the i-STAT Portable Clinical Analyzer ...

journal_title：American journal of clinical pathology

authors： Herr DM,Newton NC,Santrach PJ,Hankins DG,Burritt MF

更新日期：1995-10-01 00:00:00

abstract：:The probabilities of low transferrin saturation, folic acid, or vitamin B12 levels in association with various erythrocyte indices was determined from the prevalences of these abnormalities and the distributions of the indices among 206 hospitalized and 1,000 ambulatory anemic patients. At mean corpuscular hemoglobin ...

journal_title：American journal of clinical pathology

authors： Griner PF,Oranburg PR

更新日期：1978-11-01 00:00:00

abstract：:A tumor of the larynx composed of a small infiltrating and well-differentiated squamous cell carcinoma and a large polypoid sarcomatous mass showing the histologic features of the malignant giant cell tumor of soft parts (MGCT) is reported. Other types of sarcomatous components have been described with squamous cell c...

journal_title：American journal of clinical pathology

authors： Alguacil-Garcia A,Alonso A,Pettigrew NM

更新日期：1984-09-01 00:00:00

abstract：:The uptake and storage of 5-hydroxytryptamine by human platelets from normal donors and patients with the carcinoid syndrome are reported. When platelets were incubated in the presence of 3H-5-hydroxytryptamine (50 microM), an initial phase of rapid uptake was observed until 5-hydroxytryptamine levels of 1--2 microgra...

journal_title：American journal of clinical pathology

authors： Lewis JC,Moertel CG

更新日期：1978-10-01 00:00:00

abstract：:To study the distribution of lactate dehydrogenase (LDH-1) (H4) in normal, ischemic, and necrotic myocardium using the peroxidase-antiperoxidase technic, the authors studied formalin-fixed paraffin-embedded sections of human (n = 11) and canine (n = 28) myocardium. All normal control myocardium showed positive immunos...

journal_title：American journal of clinical pathology

authors： Herscher LL,Siegel RJ,Said JW,Edwalds GM,Moran MM,Fishbein MC

更新日期：1984-02-01 00:00:00

abstract：:Bone marrow biopsy specimens taken on initial investigation of 134 patients with hairy cell leukemia (HCL) were processed into plastic, and sections cut at 3 microns were used for histologic and histomorphometric evaluation. Twenty-four clinical, 10 histologic, and four histomorphometric variables were tested for thei...

journal_title：American journal of clinical pathology

authors： Bartl R,Frisch B,Hill W,Burkhardt R,Sommerfeld W,Sund M

更新日期：1983-05-01 00:00:00

abstract：:To study the histogenesis of and determine the most useful markers for diagnosing anaplastic thyroid carcinoma (ATC), 32 cases, including 2 with numerous osteoclast-like cells, were stained with a battery of antibodies to epithelial (keratin, epithelial membrane antigen [EMA], carcinoembryonic antigen [CEA]), mesenchy...

journal_title：American journal of clinical pathology

authors： Ordóñez NG,El-Naggar AK,Hickey RC,Samaan NA

更新日期：1991-07-01 00:00:00

abstract：:Riedel thyroiditis (RT) is an uncommon form of chronic thyroiditis in which the thyroid gland is replaced by fibrous tissue. The etiologic mechanisms underlying RT are unclear: the prevailing view is that it is part of a generalized fibroinflammatory process also involving other organs. The clinical manifestations of ...

journal_title：American journal of clinical pathology

authors： Papi G,LiVolsi VA

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVES:To support our Lean culture of continuous improvement, we implemented a daily management system designed so critical metrics of operational success were the focus of local teams to drive improvements. METHODS:We innovated a standardized visual daily management board composed of metric categories of Quality,...

journal_title：American journal of clinical pathology

authors： Zarbo RJ,Varney RC,Copeland JR,D'Angelo R,Sharma G

更新日期：2015-07-01 00:00:00

abstract：:Determination of breast cancer estrogen receptor (ER) status as a predictor of tumor response to adjuvant endocrine therapy remains a mainstay of breast cancer management. Recent second generation anti-ER antibodies and new epitope retrieval methods have produced paraffin-based immunohistochemical results that correla...

journal_title：American journal of clinical pathology

authors： Nichols GE,Frierson HF Jr,Boyd JC,Hanigan MH

更新日期：1996-09-01 00:00:00

abstract：:We sought to characterize how well computerized "case flags" performed in evaluating critical diagnoses in anatomic pathology. All cases identified by a pathologist at sign-out and flagged as a critical diagnosis in anatomic pathology in 2 hospital laboratories during a 3-year period were reviewed. A subset of all cri...

journal_title：American journal of clinical pathology

authors： Renshaw A,Gould EW

更新日期：2012-03-01 00:00:00

abstract：:Patients using anticoagulation point-of-care (POC) monitors are advised to periodically test these systems against laboratory methods to monitor performance. The international normalized ratio (INR), however, can vary between test systems owing to different instrument-reagent combinations. In a randomized study evalua...

journal_title：American journal of clinical pathology

authors： Sunderji R,Gin K,Shalansky K,Carter C,Chambers K,Davies C,Schwartz L,Fung A

更新日期：2005-02-01 00:00:00

abstract：:A case of florid proliferative sialometaplasia arising in salivary ductal inclusions in an intraparotid lymph node is described. This lesion probably represents an exuberant response to sialadenitis. Other entities that enter into its differential diagnosis in this particular location are discussed. Except for Warthin...

journal_title：American journal of clinical pathology

authors： Goldman RL,Klein HZ

更新日期：1986-07-01 00:00:00

abstract：:A unique case of intramural uterine tumor composed of malignant epithelium and benign smooth muscle, adipose tissue, and cartilage is reported. This tumor, which the authors designated "carcinomesenchymoma," apparently represents an example of a previously unreported variant of mixed müllerian tumor that is composed o...

journal_title：American journal of clinical pathology

authors： Chen KT,Vergon JM

更新日期：1981-05-01 00:00:00

abstract：:An evaluation of the change in the former close relationship between the patient and his physician, and the contribution of the pathologist to its development, is presented. The effect of these changes on the interest in and care of the patient by all in the hospital in this changing medical scene is decried; the pati...

journal_title：American journal of clinical pathology

authors： Angrist AA

更新日期：1975-07-01 00:00:00

abstract：:Functional assays for heparin cofactor II (HC-II) are based on the inactivation of thrombin by HC-II in the presence of dermatan sulfate (DS). Residual thrombin is measured in a chromogenic assay. Interference by the antithrombin-III (AT-III)/heparin complex, which also rapidly inactivates thrombin, must be eliminated...

journal_title：American journal of clinical pathology

authors： Nakhleh R,Vogt JM,Edson JR

更新日期：1988-03-01 00:00:00

abstract：:The cytopathologic findings of 196 cases of cancer of the breast were correlated with the hormonal receptor levels. The strict cytologic criteria that allow a positive diagnosis to be used as bases for definitive treatment include adequate cellularity, lack of cohesion, and nuclear abnormalities, including increased n...

journal_title：American journal of clinical pathology

authors： Kern WH

更新日期：1982-12-01 00:00:00

abstract：:This study compared the ability to diagnose and accurately classify hepatic mass lesions by ultrasound-guided biopsy using two different needle types: a 20 gauge needle that yielded primarily cytologic material and an 18 gauge automated core biopsy needle. Slides prepared from each of the needle types were separately ...

journal_title：American journal of clinical pathology

authors： Dusenbery D,Ferris JV,Thaete FL,Carr BI

更新日期：1995-11-01 00:00:00

abstract：:Serum bicarbonate testing has been reported to be inaccurate in several clinical studies. This prompted a search for systemic errors in bicarbonate testing devices, which has been inconclusive. The effect on serum bicarbonate level measurement of partially filling plain red-top (clot) vacutainer tubes was studied in h...

journal_title：American journal of clinical pathology

authors： Herr RD,Swanson T

更新日期：1992-02-01 00:00:00

abstract：:Estrogen receptor (ER) status of breast carcinomas determines prognosis and treatment. Biochemical ER assays are expensive and time-consuming and require fresh tumor. Immunohistochemical ER was assessed in 68 breast carcinomas, by an automated method using routinely processed formalin-fixed paraffin-embedded tissues, ...

journal_title：American journal of clinical pathology

authors： Cohen C,Unger ER,Sgoutas D,Bradley N,Chenggis M

更新日期：1989-11-01 00:00:00

abstract：:The authors report a case of metastatic prostate cancer masquerading as a primary lung tumor. Histologically, the lung tumor displayed eosinophilic crystalloids in the malignant glands typical of those previously described in prostatic adenocarcinoma. Review of histologic material from 30 additional patients with meta...

journal_title：American journal of clinical pathology

authors： Molberg KH,Mikhail A,Vuitch F

更新日期：1994-03-01 00:00:00

abstract：:In order to determine the significance of 40% or more leukemic cells in hand-mirror configuration in the bone marrow (hand-mirror cell leukemia), eight of 34 cases of acute lymphoblastic leukemia and one of 17 cases of acute myeloblastic leukemia were collected from a six-year period. Five of the eight patients who ha...

journal_title：American journal of clinical pathology

authors： Glassy EF,Sun NC,Okun DB

更新日期：1980-11-01 00:00:00

abstract：OBJECTIVES:We postulated that lymph node (LN) harvest and LN size are influenced by immunologic effects. METHODS:To investigate this hypothesis, we performed a retrospective analysis of 170 node-negative colon cancer cases to evaluate the density of intratumoral T lymphocytes (ITLs). CD3- and CD8-positive T cells were...

journal_title：American journal of clinical pathology

authors： Märkl B,Wieberneit J,Kretsinger H,Mayr P,Anthuber M,Arnholdt HM,Schenkirsch G

更新日期：2016-06-01 00:00:00