Heparin cofactor II assay. Elimination of heparin and antithrombin-III effects.

abstract：OBJECTIVES:Nucleic acid amplification tests on formalin-fixed, paraffin-embedded (FFPE) tissue specimens enable Mycobacterium tuberculosis complex (MTB) detection and rapid tuberculosis diagnosis in the absence of microbiologic culture tests. We aimed to evaluate the efficacy of different polymerase chain reaction (PCR...

journal_title：American journal of clinical pathology

authors： Seo AN,Park HJ,Lee HS,Park JO,Chang HE,Nam KH,Choe G,Park KU

更新日期：2014-09-01 00:00:00

abstract：:A number of variables thought to affect measurement of prothrombin time (PT) and partial thromboplastin time (PTT) were examined in an effort to determine more precisely their effects on these measurements. On the basis of these studies, it is proposed that blood specimens be anticoagulated with one part 3.8% (w./v.) ...

journal_title：American journal of clinical pathology

authors： Koepke JA,Rodgers JL,Ollivier MJ

更新日期：1975-11-01 00:00:00

abstract：:Four commercially available herpes simplex virus 1 (HSV-1) indirect fluorescent antibody (IFA) kits were compared with the use of sera selected because they were negative for HSV antibody by complement fixation (CF less than 1:8) and by ELISA (less than 1:100). However, 14 of 24 (58.3%) of these HSV-1 antibody-negativ...

journal_title：American journal of clinical pathology

authors： Rand KH,Houck HJ,Dickinson M

更新日期：1986-12-01 00:00:00

abstract：:Transketolases link the Embden-Meyerhof pathway to the pentose phosphate pathway. An influence of p-Akt on this metabolism was described. This study was performed to compare the expression of transketolase-like 1 (TKTL1) and p-Akt in glioblastoma multiforme (GBM) and other astrocytic gliomas (AGs, grades II and III). ...

journal_title：American journal of clinical pathology

authors： Völker HU,Hagemann C,Coy J,Wittig R,Sommer S,Stojic J,Haubitz I,Vince GH,Kämmerer U,Monoranu CM

更新日期：2008-07-01 00:00:00

abstract：:An on-line computer-assisted pathology encoding and reportying system (CAPER) has been developed by the Department of Pathology and Laboratory of Computer Science of the Massachusetts General Hospital for a department of surgical pathology that processes more than 25,000 specimens yearly. CAPER performs clerical funct...

journal_title：American journal of clinical pathology

authors： Aller RD,Robboy SJ,Poitras JW,Altshuler BS,Cameron M,Prior MC,Miao S,Barnett GO

更新日期：1977-12-01 00:00:00

abstract：:A case of fetal demise and maternal recovery after acetaminophen overdose is presented, to our knowledge the first reported. Fetal liver and maternal serum concentrations indicate overdose to be the cause of fetal death. Maternal disseminated intravascular coagulation (DIC) may have been related to maternal acetaminop...

journal_title：American journal of clinical pathology

authors： Haibach H,Akhter JE,Muscato MS,Cary PL,Hoffmann MF

更新日期：1984-08-01 00:00:00

abstract：:Although acute myeloid leukemias (AMLs) cytochemically negative for myeloperoxidase are now well recognized, myeloid surface antigen-negative AMLs are rare. The morphologic, cytochemical, immunologic, and cytogenetic or molecular features of such cases are described in four adults aged 19 to 60 years. All had AML with...

journal_title：American journal of clinical pathology

authors： Arber DA,Glackin C,Lowe G,Medeiros LJ,Slovak ML

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVES:To describe four cases of an uncommon type of acalculous cholecystitis/cholangitis characterized by increased intraepithelial lymphocytes within the biliary epithelium. METHODS:Cases were prospectively compiled during regular surgical pathology sign-out. Clinical information was obtained from the electronic...

journal_title：American journal of clinical pathology

authors： Jessurun J

更新日期：2015-01-01 00:00:00

abstract：:Reducing the rate of avoidable errors is crucial to patient safety. Telephone calls with misunderstood critical results constitute one area in which opportunities for improvement exist. The aviation industry has dealt with this issue by requiring pilots to repeat instructions received from the air traffic controller. ...

journal_title：American journal of clinical pathology

authors： Barenfanger J,Sautter RL,Lang DL,Collins SM,Hacek DM,Peterson LR

更新日期：2004-06-01 00:00:00

abstract：:Urine myoglobin concentrations are measured clinically to assess rhabdomyolysis and the related risk of renal damage. We studied urine myoglobin concentrations in vitro to explore the factors affecting stability. Myoglobin was very unstable in urine specimens, especially below pH 6.5, and its immunoreactivity deterior...

journal_title：American journal of clinical pathology

authors： Chen-Levy Z,Wener MH,Toivola B,Daum P,Reyes M,Fine JS

更新日期：2005-03-01 00:00:00

abstract：:Screening for serum lipid disorders is recommended by numerous specialty societies to identify patients at risk for coronary heart disease (CHD). The best screening tests will identify patients at highest risk for CHD who would benefit from intervention. This report discusses an appropriate test panel to use as the in...

journal_title：American journal of clinical pathology

authors： Hostetter AL

更新日期：1995-04-01 00:00:00

abstract：:Human papillomaviruses (HPVs) are associated with benign and malignant neoplasms of the cervix. One of the criteria for their etiologic role requires an assessment of whether virtually all or only a small fraction of lesions contain viral genomes. DNA preparations from colposcopically directed punch biopsies of cervic...

journal_title：American journal of clinical pathology

authors： Tham KM,Chow VT,Singh P,Tock EP,Ching KC,Lim-Tan SK,Sng IT,Bernard HU

更新日期：1991-05-01 00:00:00

abstract：:The authors tested a newly-developed computerized laser scanning cytometer (LSC) as a means of performing immunophenotypic analysis of hematologic specimens within their community hospital. Results were compared on a case-by-case basis with parallel flow cytometric and immunohistochemical data. A total of 71 specimens...

journal_title：American journal of clinical pathology

authors： Clatch RJ,Walloch JL,Zutter MM,Kamentsky LA

更新日期：1996-06-01 00:00:00

abstract：:Eosinophils are normally absent from the urine. Their presence has been associated with a variety of clinical conditions affecting the kidney or urinary tract. The authors examined the clinical significance and eosinophils, in particular, for acute interstitial nephritis. ...

journal_title：American journal of clinical pathology

authors： Corwin HL,Haber MH

更新日期：1987-10-01 00:00:00

abstract：:In the absence of clinical signs, elevated values of the cardiac isoforms of troponin T (cTnT) and I (cTnI) can be found in the serum samples of some patients with skeletal muscle myopathies; the cause is unclear. We studied the messenger RNA (mRNA) expression of cTnT and cTnI in the skeletal muscles of 24 patients wi...

journal_title：American journal of clinical pathology

authors： Messner B,Baum H,Fischer P,Quasthoff S,Neumeier D

更新日期：2000-10-01 00:00:00

abstract：:Thrombocytosis may reflect a primary myeloproliferative disorder or be a secondary reaction to other pathologic processes. Patients with persistent unexplained thrombocytosis meeting criteria of primary thrombocythemia had elevated levels of serum lactic dehydrogenase, whereas comparable patients with secondary thromb...

journal_title：American journal of clinical pathology

authors： Budman DR,Lackner H,Berczeller P,Silber R

更新日期：1981-06-01 00:00:00

abstract：:An evaluation of the performance of duplicate prothrombin time (PT) and activated partial thromboplastin time (aPTT) assays was undertaken to develop analytical duplicate performance criteria in order to quantitate the risks associated with singlet versus duplicate procedures. Data were retrospectively collected from ...

journal_title：American journal of clinical pathology

authors： Scheer WD,Catrou PG,Lipscomb GE,Boudreau DA

更新日期：1986-04-01 00:00:00

abstract：:Bone marrow angiogenesis in patients with idiopathic myelofibrosis (IM) was evaluated by using a quantitative morphometric analysis test system. IM specimens had a significantly higher degree of bone marrow microvessel density (MVD) compared with control specimens. The higher degree of angiogenesis was associated with...

journal_title：American journal of clinical pathology

authors： Ni H,Barosi G,Hoffman R

更新日期：2006-08-01 00:00:00

abstract：:The incubation of stored blood in a mixture of inosine, pyruvate, glucose, and phosphate restores the O2 affinity of hemoglobin to physiologic levels, as measured by the configuration of the dissociation curve and the P50. This regeneration of normal hemoglobin function not only is consistent for samples anticoagulate...

journal_title：American journal of clinical pathology

authors： Sumoza A,Fairbanks VF,Pineda AA

更新日期：1977-07-01 00:00:00

abstract：:The t(3;21)(q26.2;q22) translocation is rare in cases of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). We studied 17 patients with MDS/AML associated with t(3;21) and compared them with 17 patients with MDS associated with inv(3) (q21q26.2)/t(3;3)(q21;q26.2), because these entities share 3q26 locus ...

journal_title：American journal of clinical pathology

authors： Li S,Yin CC,Medeiros LJ,Bueso-Ramos C,Lu G,Lin P

更新日期：2012-07-01 00:00:00

abstract：:Determination of HER-2/neu oncogene amplification has become clinically important in the present management of breast cancer and may have important applications in other areas of clinical oncology and scientific research. In situ hybridization is an extremely accurate and sensitive technique for assessing amplificatio...

journal_title：American journal of clinical pathology

authors： Gupta D,Middleton LP,Whitaker MJ,Abrams J

更新日期：2003-03-01 00:00:00

abstract：:The most common differentiated renal tumor of early childhood is the congenital mesoblastic neophroma. Well-differentiated forms of Wilms' tumor may present a difficult differential diagnosis from these benign neoplasms. The cases of two patients found to have well-differentiated renal neoplasms after being treated fo...

journal_title：American journal of clinical pathology

authors： Hughson MD,Hennigar GR,Othersen HB Jr

更新日期：1976-08-01 00:00:00

abstract：:The development of a consistent strategy for the analysis of oncogene expression at the cellular level is essential for understanding the roles of these genes in the development and progression of human neoplasia. Detection of the neu oncogene products in breast carcinoma was selected as a model for analysis of oncoge...

journal_title：American journal of clinical pathology

authors： Naber SP,Tsutsumi Y,Yin S,Zolnay SA,Mobtaker H,Marks PJ,McKenzie SJ,DeLellis RA,Wolfe HJ

更新日期：1990-08-01 00:00:00

abstract：:Cholesterol content of the high-density lipoproteins has become of interest in evaluating the risk of development of coronary heart disease. There is an inverse relationship between high-density lipoprotein cholesterol and risk. The authors found a significant bias (11.1 mg/dl; 0.289 mmol/l) in a comparison of a rapid...

journal_title：American journal of clinical pathology

authors： Gerson B,Dean L,Copeland BE

更新日期：1979-05-01 00:00:00

abstract：:It is said that HER2/neu expression by immunohistochemical analysis varies with the time of fixation. The purpose of this pilot study was to determine the impact of the length of fixation in 10% buffered formalin on the expression of HER2/neu by immunohistochemical analysis. We studied tissue samples from 10 invasive ...

journal_title：American journal of clinical pathology

authors： Ibarra JA,Rogers LW

更新日期：2010-10-01 00:00:00

abstract：:A comparative evaluation of two commercial kits that detect antinuclear antibodies via indirect immunofluorescence was undertaken using an adult ambulatory population. The sensitivity and specificity of the kits were compared to determine which of the two was more efficient as a screening test for systemic lupus eryth...

journal_title：American journal of clinical pathology

authors： Valdiserri RO,Petronie JS

更新日期：1984-03-01 00:00:00

abstract：OBJECTIVES:Certain laboratory tests are critical for patient care and must be communicated rapidly. Professional societies have developed guidelines for reporting of "critical values" and significant or unexpected surgical pathology findings. Urgent diagnoses requiring rapid reporting include new or unexpected diagnose...

journal_title：American journal of clinical pathology

authors： Layfield LJ,Schnabel JL

更新日期：2014-12-01 00:00:00

abstract：:Marfan syndrome is one of the most common connective tissue diseases and may manifest with a range of symptoms and pathologic changes. We present a retrospective series of 5 cases of patients with Marfan syndrome and pulmonary pathology. Patients were young to middle-aged adults with absent or minimal smoking historie...

journal_title：American journal of clinical pathology

authors： Dyhdalo K,Farver C

更新日期：2011-12-01 00:00:00

abstract：:Intrauterine clostridial infections have historically been associated with puerperal sepsis, often subsequent to instrumented abortions. Isolated reports have been associated with a malignant neoplasm or degenerating leiomyoma, most often after instrumentation, radiation therapy, or chemotherapy. In these cases, well-...

journal_title：American journal of clinical pathology

authors： Hogan SF,Ireland K

更新日期：1989-01-01 00:00:00

abstract：:The resources needed to operate a clinical chemistry laboratory are known only as rough approximations. In order to gather more information about these resources, a 13-page questionnaire was completed by 50 pathology departments of which 38 departments provided adequate information about their clinical chemistry secti...

journal_title：American journal of clinical pathology

authors： Elin RJ,Robertson EA,Sever G

更新日期：1982-12-01 00:00:00