The determination of reference values for hematologic parameters using results obtained from patient populations.

abstract：:Worldwide, infection with hepatitis viruses remains a major clinical and public heath concern. The laboratory is an integral part of the diagnosis of these infections since many of the manifestations are nonspecific, and the various hepatitis viruses show overlapping symptomatology. In this article, we discuss the lab...

journal_title：American journal of clinical pathology

authors： Harris KR,Dighe AS

更新日期：2002-12-01 00:00:00

abstract：:We evaluated a more efficient method of processing liquid-based cervical cytology specimens for human papillomavirus (HPV) DNA testing by Hybrid Capture II (HCII). Aliquots were made from 701 specimens in the following sequence: 4.0, 2.0, 1.0, 0.5, and 1.5 mL. The 4.0-mL aliquot was processed by the standard method (S...

journal_title：American journal of clinical pathology

authors： Castle PE,Garcia-Meijide M,Holladay EB,Chuke R,Payne J,Long A,Siefers H,Demuth F,Lorincz AT

更新日期：2005-02-01 00:00:00

abstract：:Thirty drugs used primarily in critical care and hospital settings were tested in vitro to observe interference on glucose measurements with 6 hand-held glucose meters and a portable glucose analyzer. Paired differences of glucose measurements between drug-spiked samples and unspiked control samples were calculated to...

journal_title：American journal of clinical pathology

authors： Tang Z,Du X,Louie RF,Kost GJ

更新日期：2000-01-01 00:00:00

abstract：:Terminal deoxynucleotidyl transferase (TdT) is a marker of lymphoblastic disorders. Previously, the technique for determining TdT on smears was by indirect immunofluorescence. An immunoperoxidase procedure for detecting TdT on smears is reported. Results are in a comparable range with the indirect immunofluorescent te...

journal_title：American journal of clinical pathology

authors： Stass SA,Dean L,Peiper SC,Bollum FJ

更新日期：1982-02-01 00:00:00

abstract：OBJECTIVES:B-lymphoblastic leukemia (B-LBL) arising in patients with chronic lymphocytic leukemia (CLL) is exceedingly rare and poorly characterized. METHODS:We describe four patients with CLL and concurrent or subsequent B-LBL diagnosed by morphologic, immunophenotypic, cytogenetic, and molecular analysis and reviewe...

journal_title：American journal of clinical pathology

authors： Chakhachiro Z,Yin CC,Abruzzo LV,Aladily TN,Barron LL,Banks HE,Thomas DA,Keating M,Medeiros LJ,Huh YO

更新日期：2015-08-01 00:00:00

abstract：:The diagnostic value of glypican 3 (GPC3) immunostaining on needle biopsy specimens has not been well assessed. In this study, 120 liver needle biopsy specimens, including 46 from cirrhotic livers and 74 hepatocellular carcinomas (HCCs), were immunohistochemically examined for expression of GPC3. The results showed st...

journal_title：American journal of clinical pathology

authors： Anatelli F,Chuang ST,Yang XJ,Wang HL

更新日期：2008-08-01 00:00:00

abstract：:The serum concentrations of alpha-fetoprotein of rats following experimental galactosamine-induced liver-cell necrosis accurately reflect the severity of preceding liver-cell damage as determined by elevation of serum transaminases. There is a very close correlation between the highest SGOT or SGPT serum activity foun...

journal_title：American journal of clinical pathology

authors： Sell S,Stillman D,Gochman N

更新日期：1976-11-01 00:00:00

abstract：:A study was made of quantitative urine cultures in bacteremic patients with urinary tract infection as the only identifiable source. These patients represent the most serious form of urinary tract infection and should be recognized as significant by the criteria used for interpreting quantitative urine cultures. In 83...

journal_title：American journal of clinical pathology

authors： Roberts FJ

更新日期：1986-05-01 00:00:00

abstract：:Venous thromboembolism (VTE) results from the interaction of the Virchow triad (venous stasis, endothelial injury, and hypercoagulability). Risk factors for increased hypercoagulability, or thrombophilia, include activated protein C resistance/factor V Leiden, the prothrombin G20210A mutation, deficiencies of the natu...

journal_title：American journal of clinical pathology

authors： Ballard RB,Marques MB,Education Committee of the Academy of Clinical Laboratory Physicians and Scientists.

更新日期：2012-04-01 00:00:00

abstract：:Anemia developing during the course of chronic renal disease is a frequent complication often necessitating periodic transfusion therapy. A number of etiologic factors have been implicated, including decreased production of erythropoietin; decreased erythrocyte life span secondary to uremia and splenomegaly; increased...

journal_title：American journal of clinical pathology

authors： Hancock DE,Onstad JW,Wolf PL

更新日期：1976-01-01 00:00:00

abstract：:In five patients with eosinophilia and myeloproliferative disorders, the IgE levels were normal, and immune complexes were not detected. In contrast, in six patients with reactive eosinophilia accompanying immunologic diseases, the IgE levels were elevated in five, and immune complexes were elevated in two. Five of si...

journal_title：American journal of clinical pathology

authors： Crowley JP,Myers TJ

更新日期：1983-03-01 00:00:00

abstract：:Increasingly, all automated blood counts are not accompanied by a microscopic white blood cell differential. A popular strategy is to obtain a manual differential if any part of the automated blood count and differential is outside specified limits (the "diff-if" strategy). The authors compared two sets of criteria to...

journal_title：American journal of clinical pathology

authors： McClure S,Bates JE,Harrison R,Gilmer PR,Bessman JD

更新日期：1988-08-01 00:00:00

abstract：:This article explores 3 aspects of breast diagnosis that are currently under investigation and about which our thinking has recently undergone considerable reshaping. The trend toward more frequent evaluation of clinically subtle lesions has suggested that it might be necessary to understand thefine-needle aspiration ...

journal_title：American journal of clinical pathology

authors： Stanley MW,Sidawy MK,Sanchez MA,Stahl RE,Goldfischer M

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVES:Mesothelin (MSLN) is a differentiation antigen found to be overexpressed in intraductal papillary mucinous neoplasms (IPMNs) and is a potential treatment target in pancreatic ductal adenocarcinoma. METHODS:From institutional archives, 114 cases of resected pancreatic mucinous cysts were identified, includin...

journal_title：American journal of clinical pathology

authors： Frank R,Li S,Ahmad NA,Sepulveda AR,Jhala NC

更新日期：2014-09-01 00:00:00

abstract：:Cryostat sections from fully developed papular lesions of lymphomatoid papulosis (histologic subtype A or B) have been examined by immunoenzymatic staining with 24 monoclonal antibodies against lymphoid cells and their subsets. The lesions demonstrated essentially identical cellular compositions and consisted of T-lym...

journal_title：American journal of clinical pathology

authors： Ralfkiaer E,Stein H,Wantzin GL,Thomsen K,Ralfkiaer N,Mason DY

更新日期：1985-11-01 00:00:00

abstract：:Transketolases link the Embden-Meyerhof pathway to the pentose phosphate pathway. An influence of p-Akt on this metabolism was described. This study was performed to compare the expression of transketolase-like 1 (TKTL1) and p-Akt in glioblastoma multiforme (GBM) and other astrocytic gliomas (AGs, grades II and III). ...

journal_title：American journal of clinical pathology

authors： Völker HU,Hagemann C,Coy J,Wittig R,Sommer S,Stojic J,Haubitz I,Vince GH,Kämmerer U,Monoranu CM

更新日期：2008-07-01 00:00:00

abstract：:Functional assays for heparin cofactor II (HC-II) are based on the inactivation of thrombin by HC-II in the presence of dermatan sulfate (DS). Residual thrombin is measured in a chromogenic assay. Interference by the antithrombin-III (AT-III)/heparin complex, which also rapidly inactivates thrombin, must be eliminated...

journal_title：American journal of clinical pathology

authors： Nakhleh R,Vogt JM,Edson JR

更新日期：1988-03-01 00:00:00

abstract：:Lymphocyte subpopulations were studied in the peripheral blood, lymph nodes, and spleens in a group of 17 patients with untreated Hodgkin's disease. In 12 of 15 cases, diminished absolute levels of T-lymphocytes in the peripheral blood were found; however, this was correlated with total lymphopenia. No direct relation...

journal_title：American journal of clinical pathology

authors： Bukowski RM,Noguchi S,Hewlett JS,Deodhar S

更新日期：1976-01-01 00:00:00

abstract：:Session 1 of the 2007 Workshop of the Society for Hematopathology/European Association for Haematopathology focused on chronic myelogenous leukemia, BCR-ABL1+ (CML). CML is a myeloproliferative neoplasm arising at the level of a pluripotent stem cell and consistently associated with the BCR-ABL1 fusion gene. CML most ...

journal_title：American journal of clinical pathology

authors： Vardiman JW

更新日期：2009-08-01 00:00:00

abstract：:Monoclonal antibody (MoAb) 44-3A6 recognizes a glandular differentiation-associated antigen and has been used to identify exocrine differentiation in pulmonary carcinomas. The authors assessed its value in the diagnosis of lung carcinomas metastatic to lung/pleura and pleural malignant mesothelioma (MM), using cell bl...

journal_title：American journal of clinical pathology

authors： Spagnolo DV,Whitaker D,Carrello S,Radosevich JA,Rosen ST,Gould VE

更新日期：1991-03-01 00:00:00

abstract：:Abbreviated pretransfusion testing, although permitted by American Association of Blood Banks Standards for unimmunized patients, is not widely practiced. Concerns remain about optimal antibody screening methods, antibodies missed by deleting the antiglobulin crossmatch, and cost-effectiveness. The authors prospective...

journal_title：American journal of clinical pathology

authors： Cordle DG,Strauss RG,Snyder EL,Floss AM

更新日期：1990-10-01 00:00:00

abstract：:Upon hospital admission a patient was found to have severe anemia and a strongly positive direct antiglobulin test (DAT). The patient was taking probenecid periodically for gout. An antibody was detected in the patient's serum that only reacted with red blood cells (RBCs) when probenecid was added. Eluates from the pa...

journal_title：American journal of clinical pathology

authors： Sosler SD,Behzad O,Garratty G,Lee CL,Postoway N,Khomo O

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVES:This study examines whether the assumptions that pathologists understand the medical malpractice negligence rule and have a clear single standard of care are reasonable. METHODS:Two hundred eighty-one Texas academic pathologists and trainees were presented 10 actual pathology malpractice cases from publicly...

journal_title：American journal of clinical pathology

authors： Allen TC,Stafford M,Liang BA

更新日期：2014-04-01 00:00:00

abstract：:Coronary artery disease (CAD) is the leading cause of death in the United States. Increasing evidence suggests involvement of inflammation in the atherosclerotic process. We examined cytokines and other inflammatory markers in 865 patients with chest pain in whom coronary angiography revealed no evidence of CAD or CAD...

journal_title：American journal of clinical pathology

authors： Martins TB,Anderson JL,Muhlestein JB,Horne BD,Carlquist JF,Roberts WL,Carlquist JF

更新日期：2006-06-01 00:00:00

abstract：:Mucocele-like tumors of the breast originally were reported by Rosen in 1986 as benign lesions that histologically resembled colloid carcinoma of the breast. The authors document two cases of mucocele-like tumors to illustrate the difficulty in separating these lesions from colloid carcinoma on the basis of fine-needl...

journal_title：American journal of clinical pathology

authors： Bhargava V,Miller TR,Cohen MB

更新日期：1991-06-01 00:00:00

abstract：:Using Venn diagrams derived from set theory, a mathematic model is presented that allows triple-label immunophenotypic analysis of cells based upon double-label measurements. Practical applications of this method are illustrated and discussed. Using this model, triple-label data concerning Leu-8 and Leu-9 (CD7) antige...

journal_title：American journal of clinical pathology

authors： Wood GS

更新日期：1989-07-01 00:00:00

abstract：:The professional activities of anatomic and clinical pathologists involve, to a large extent, management issues. To evaluate the management training received by pathology residents, the authors surveyed pathology residency training programs in the United States. Responses were collected from 138 of 187 programs (73.8%...

journal_title：American journal of clinical pathology

authors： Brugnara C,Fenton T,Winkelman JW

更新日期：1994-05-01 00:00:00

abstract：:Because of the unusual presentation of pernicious anemia in many black women, a further characterization of this disease among the different racial groups was undertaken. The following were found. (1) Black women under the age of 50 years had a significantly lower prevalence of anti-parietal cell antibody than did "Eu...

journal_title：American journal of clinical pathology

authors： Carmel R,Ozturk G,Johnson CS,Tung KS,Terasaki PI

更新日期：1981-03-01 00:00:00

abstract：OBJECTIVES:Promotion of high-quality care at a lower cost requires educational initiatives across the continuum of medical education. A needs assessment was performed to inform the design of an educational tool with the goal of teaching laboratory stewardship to medical students. METHODS:The needs assessment consisted...

journal_title：American journal of clinical pathology

authors： Roth CG,Huang WY,Caruso AC,Sekhon N,Kung DH,Greely JT,Du YB,Holder-Haynes JG,Little JE,Fielder EK,Ismail NJ

更新日期：2020-01-01 00:00:00

abstract：:A goat anti-serum was prepared against mucinous ovarian cyst fluid and absorbed with normal colon and a variety of normal tissues until the only residual immunoreactivity was directed against colon cancer and ovarian tumor mucin. The set of antigenic determinants defined by this anti-serum has been called COTA, standi...

journal_title：American journal of clinical pathology

authors： Pant KD,Fenoglio-Preiser CM,Berry CO,Zamora PO,Ram MD,Fulks RM,Rhodes BA

更新日期：1986-07-01 00:00:00