Congenital hemophagocytic reticulosis.

abstract：:Breast cancer is the result of a multistage carcinogenic process. Initiation, promotion, dependency and autonomy make up a sequence of experimentally distinguishable phases of this process. Progression--the transition from dependency on hormonal support to autonomy--is demonstrable clinically. High-affinity saturatabl...

journal_title：American journal of clinical pathology

authors： Brennan MJ

更新日期：1975-12-01 00:00:00

abstract：OBJECTIVES:Many nonpathologists and some pathologists consider utilization review essential to laboratory quality improvement, but (1) confusion surrounding the definition of "appropriate" laboratory utilization, (2) the reliance on manual chart review, and (3) a lack of leadership have contributed to its unstandardize...

journal_title：American journal of clinical pathology

authors： Hauser RG,Shirts BH

更新日期：2014-06-01 00:00:00

abstract：:A patient with acquired von Willebrand disease associated with multiple myeloma (IgG-lambda) is described. Mixture of his plasma or IgG fraction with washed control platelets resulted in the inhibition of aggregation with ristocetin, but mixture of control plasma or IgG fraction with washed patient platelets showed no...

journal_title：American journal of clinical pathology

authors： Mohri H,Noguchi T,Kodama F,Itoh A,Ohkubo T

更新日期：1987-05-01 00:00:00

abstract：Objectives:To determine whether V H family usage in B-cell lymphoproliferative disorders can be deduced from polymerase chain reaction (PCR) product-length information obtained through the BIOMED-2 (Invivoscribe, San Diego, CA) clonality assay. Methods:We develop an algorithm that uses the sizing information of the BI...

journal_title：American journal of clinical pathology

authors： McDonald TJ,Kuo L,Kuo FC

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVES:To describe the histopathologic and immunophenotypic features of a temporary splenic allograft exposed to massive donor-specific antibody (DSA) insult. METHODS:A human cadaveric donor splenic allograft was temporarily transplanted in a highly sensitized patient with the intention of removing DSA before inte...

journal_title：American journal of clinical pathology

authors： Gaitonde S,Hassan M,Mehta V,Benedetti E,Tzvetanov I,Lichvar A,Pirzada S,Setty S

更新日期：2020-11-21 00:00:00

abstract：OBJECTIVES:To examine high expression of tumor necrosis factor ligand superfamily member 13 (TNFSF13), which is correlated with several malignancies. METHODS:TNFSF13 messenger RNA expression in tumor cells and fibroblasts in a cohort of patients with non-small cell lung cancer (NSCLC) was analyzed by quantitative real...

journal_title：American journal of clinical pathology

authors： Qian Z,Qingshan C,Chun J,Huijun Z,Feng L,Qiang W,Qiang X,Min Z

更新日期：2014-02-01 00:00:00

abstract：:A markedly prolonged activated partial thromboplastin time (APTT) was observed in a 61-year-old woman with bruising and a decreasing hematocrit. Coagulation laboratory evaluation was sought to determine the cause of the prolonged APTT and bleeding. Evaluation demonstrated that, rather than identifying a coagulopathy, ...

journal_title：American journal of clinical pathology

authors： Humphries JE,Acker MN,Schnell DE,Knarr JW

更新日期：1993-08-01 00:00:00

abstract：Objectives:A report on the multicenter evaluation of the Bruker MALDI Biotyper CA System (MBT-CA; Bruker Daltonics, Billerica, MA) for the identification of clinically important bacteria and yeasts. Methods:In total, 4,399 isolates of medically important bacteria and yeasts were assessed in the MBT-CA. These included ...

journal_title：American journal of clinical pathology

authors： Wilson DA,Young S,Timm K,Novak-Weekley S,Marlowe EM,Madisen N,Lillie JL,Ledeboer NA,Smith R,Hyke J,Griego-Fullbright C,Jim P,Granato PA,Faron ML,Cumpio J,Buchan BW,Procop GW

更新日期：2017-06-01 00:00:00

abstract：:The primary role of the surgical pathologist is to diagnose, and then to transmit this information effectively so that it can be used to guide patient management; therefore, the dual roles of the surgical pathologist as a diagnostician and consultant are inextricable. The diagnostic pathologist determines the nature, ...

journal_title：American journal of clinical pathology

authors： Hutter RV

更新日期：1981-03-01 00:00:00

abstract：:We obtained data on laboratory turnaround time (TAT) and emergency department (ED) length of stay (LOS). We correlated potassium test TAT outlier percentage (TAT-OP) with ED LOS and found that for each outlier percentage (potassium result > 40 minutes), a projected impact on ED LOS was approximately 2.8 additional min...

journal_title：American journal of clinical pathology

authors： Holland LL,Smith LL,Blick KE

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVES:Method imprecision, error rates, and explanatory causes that were identified in the Institute for Quality Management in Healthcare point-of-care (POC) glucose proficiency testing (PT) program were assessed in comparison with results obtained from laboratory glucose PT surveys. METHODS:POC and laboratory glu...

journal_title：American journal of clinical pathology

authors： Aslan B,Stemp J,Yip P,Gun-Munro J

更新日期：2014-12-01 00:00:00

abstract：:We evaluated the immunohistochemical profile and specificity of CD138 reactivity in 238 specimens from hematopoietic and nonhematopoietic neoplasms. In 91 bone marrow biopsies, CD138 reactivity was observed for nonneoplastic plasma cells, neoplastic plasma cells in multiple myeloma cases (43/43), and the plasmacytic c...

journal_title：American journal of clinical pathology

authors： O'Connell FP,Pinkus JL,Pinkus GS

更新日期：2004-02-01 00:00:00

abstract：:Studies from Africa have demonstrated that black people have higher vitamin B12 (cobalamin) levels than do white people. The authors compared healthy white people, black people, and Latin-Americans in the United States. Their study is also the largest in which the effect of race and sex on the cobalamin levels has bee...

journal_title：American journal of clinical pathology

authors： Saxena S,Carmel R

更新日期：1987-07-01 00:00:00

abstract：:We studied the histologic and multiparameter flow cytometry (MFC) features of 12 cases of angioimmunoblastic T-cell lymphoma (AITL), 13 of mature T-cell lymphoma, and 25 control cases of reactive lymphoid hyperplasia to evaluate the role of CD10 in the differential diagnosis of peripheral T-cell lymphomas (PTCLs). A c...

journal_title：American journal of clinical pathology

authors： Stacchini A,Demurtas A,Aliberti S,Francia di Celle P,Godio L,Palestro G,Novero D

更新日期：2007-11-01 00:00:00

abstract：:Telepathology is gaining acceptance as a mode of providing pathology services to remote sites, but its economic feasibility is unknown. A dynamic robotic telepathology service between the Veterans Affairs Medical Center, Iron Mountain, MI, and the Veterans Affairs Medical Center, Milwaukee, WI, provides diagnostic ser...

journal_title：American journal of clinical pathology

authors： Agha Z,Weinstein RS,Dunn BE

更新日期：1999-10-01 00:00:00

abstract：:Three anti-Factor-VIII antibodies from hemophiliacs were reacted with samples of batches of Maws commerical bovine and porcine Factor VIII concentrates manufactured over a 12-year period. The apparent antibody concentrations varied widely with the different batches of concentrates. The variations are probably due to i...

journal_title：American journal of clinical pathology

authors： Edson JR,Swinehart CD

更新日期：1976-06-01 00:00:00

abstract：:To determine the current frequency of discovering important diagnoses at autopsy, the diagnoses made in all complete or "no head" autopsies during 1994 at a major tertiary care transplantation referral center were retrospectively compared with the diagnoses made antemortem. Of 176 autopsies, 79 (44.9%) revealed 1 or m...

journal_title：American journal of clinical pathology

authors： Nichols L,Aronica P,Babe C

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVES:To evaluate the predictive value of growth patterns in patients undergoing sorafenib treatment for metastatic clear cell renal cell carcinomas (CCRCCs). METHODS:Forty-eight patients were analyzed, each of whom underwent nephrectomy and received sorafenib treatment for metastatic CCRCC. Progression-free surv...

journal_title：American journal of clinical pathology

authors： Araki H,Tsuzuki T,Kimura T,Tanaka K,Yamada S,Sassa N,Yoshino Y,Hattori R,Gotoh M

更新日期：2015-04-01 00:00:00

abstract：:Venography was performed on fifty-six patients suspected of having deep venous thrombosis (DVT) of the legs. The accuracy of the D-dimer measurement in plasma using two latex tests and an enzyme-linked immunosorbent assay (ELISA) was compared with that of usual determination of total fibrin(ogen) degradation products ...

journal_title：American journal of clinical pathology

authors： Bounameaux H,Schneider PA,Reber G,de Moerloose P,Krahenbuhl B

更新日期：1989-01-01 00:00:00

abstract：:Worldwide, infection with hepatitis viruses remains a major clinical and public heath concern. The laboratory is an integral part of the diagnosis of these infections since many of the manifestations are nonspecific, and the various hepatitis viruses show overlapping symptomatology. In this article, we discuss the lab...

journal_title：American journal of clinical pathology

authors： Harris KR,Dighe AS

更新日期：2002-12-01 00:00:00

abstract：:Three stillborn fetuses are reported in which an abdominal wall defect was associated with defects in the urogenital and anal region. Autopsy of these fetuses provided clues indicative of how and where the embryonic development went wrong. The malformation involved a disturbance of the cell deposition process, occurri...

journal_title：American journal of clinical pathology

authors： Hartwig NG,Steffelaar JW,Van de Kaa C,Schueler JA,Vermeij-Keers C

更新日期：1991-11-01 00:00:00

abstract：OBJECTIVES:The metaplastic intestinal epithelium in Barrett esophagus (BE) occasionally contains Paneth cells; however, little is known regarding the prevalence and significance of Paneth cell metaplasia (PCM) in BE. METHODS:We evaluated 757 esophageal biopsy specimens with intestinal metaplasia (IM) for PCM. Outcome ...

journal_title：American journal of clinical pathology

authors： Chen W,Frankel WL,Cronley KM,Yu L,Zhou X,Yearsley MM

更新日期：2015-05-01 00:00:00

abstract：:The platelet aggregation responses induced by adenosine diphosphate (ADP) and collagen were characterized by parameters defining rate and extent of reaction. Values were compared on the basis of platelet concentration, time elapsed between sample collection and test performance, and sex of donors. Rate and extent of a...

journal_title：American journal of clinical pathology

authors： Roper P,Drewinko B,Hasler D,Johnston D,Hester J,Freireich EJ

更新日期：1979-03-01 00:00:00

abstract：:Bleeding problems are symptomatic of platelet delta-storage pool diseases (SPDs) such as Hermansky-Pudlak syndrome. Although at present no cure is available for delta-SPD, early diagnosis is of great importance for prophylactic and supportive treatment. This study tested the usefulness of a flow cytometric assay for p...

journal_title：American journal of clinical pathology

authors： Maurer-Spurej E,Pittendreigh C,Wu JK

更新日期：2007-04-01 00:00:00

abstract：:A study was made of quantitative urine cultures in bacteremic patients with urinary tract infection as the only identifiable source. These patients represent the most serious form of urinary tract infection and should be recognized as significant by the criteria used for interpreting quantitative urine cultures. In 83...

journal_title：American journal of clinical pathology

authors： Roberts FJ

更新日期：1986-05-01 00:00:00

abstract：Objectives:Early and accurate diagnosis remains crucial in the therapeutic management of invasive central nervous system fungal infections. Different molds have intrinsic resistance to antifungal agents; thus, morphologic differentiation is helpful to clinicians. Methods:Using three examples, we present a guide on how...

journal_title：American journal of clinical pathology

authors： Chavez JA,Brat DJ,Hunter SB,Velazquez Vega J,Guarner J

更新日期：2018-01-29 00:00:00

abstract：:Absolute lymphocytosis after nonsurgical trauma was investigated in three patient groups at an acute-care tertiary referral hospital. The first group, with mild-to-moderate trauma, consisted of 64 patients who survived knife wounds to the chest and abdomen. Thirteen of the 64 patients had admission lymphocyte counts g...

journal_title：American journal of clinical pathology

authors： Thommasen HV,Boyko WJ,Montaner JS,Russell JA,Johnson DR,Hogg JC

更新日期：1986-10-01 00:00:00

abstract：OBJECTIVES:Pathogenic free-living amebae (FLAs) cause skin, ocular, and central nervous system (CNS) infections with significant morbidity and mortality. Diagnosis of FLA infections by pathologic examination of tissue sections can be aided using molecular assays. This study investigated the performance characteristics ...

journal_title：American journal of clinical pathology

authors： Norgan AP,Sloan LM,Pritt BS

更新日期：2019-11-04 00:00:00

abstract：:A two-sample plot is often used to display test results in clinical chemistry external quality control programs. The use of control materials at different concentrations calls for a re-evaluation of the two-sample plot. A modification of the two-sample plot is presented. The axes of the graph are graduated in units of...

journal_title：American journal of clinical pathology

authors： Elion-Gerritzen WE

更新日期：1977-01-01 00:00:00

abstract：:In diagnostic pathology, decision-making skills are used to match the facts of a particular case to a diagnostic category. Ideally the diagnosis is established with "beyond a reasonable doubt" certainty, but substantial uncertainty orfrank diagnostic error can afflict the diagnostic process for a variety of reasons. M...

journal_title：American journal of clinical pathology

authors： Foucar E

更新日期：2001-12-01 00:00:00