Abstract:
:Histiocytosis X, multicentric reticulohistiocytosis, juvenile xanthogranuloma, the "fibrous" type of dermatofibroma, dermatofibrosarcoma protuberans, and malignant fibrous histiocytoma are all characterized by dermal and/or subcutaneous infiltrates composed at least partially of cells having morphologic features suggestive of histiocytes. Paraffin-embedded tissues representing these conditions were stained for lysozyme (muramidase) with a peroxidase-antiperoxidase technic. The cells of juvenile xanthogranuloma were rich in lysozyme. Some of the cells of histiocytosis X showed a positive pattern, and the cells of the other three conditions were essentially negative. This study confirmed the histiocytic nature of juvenile xanthogranuloma and multicentric reticulohistiocytosis, supported the interpretation that there is a histiocytic component in the lesions of histiocytosis X, and cast some doubt on the alleged histiocytic nature of "fibrous" dermatofibroma, dermatofibrosarcoma protuberans, and malignant fibrous histiocytoma.
journal_name
Am J Clin Patholjournal_title
American journal of clinical pathologyauthors
Burgdorf WH,Duray P,Rosai Jdoi
10.1093/ajcp/75.2.162subject
Has Abstractpub_date
1981-02-01 00:00:00pages
162-7issue
2eissn
0002-9173issn
1943-7722journal_volume
75pub_type
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journal_title:American journal of clinical pathology
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更新日期:1982-04-01 00:00:00
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更新日期:2003-07-01 00:00:00
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journal_title:American journal of clinical pathology
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更新日期:1981-04-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2014-08-01 00:00:00
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更新日期:1985-11-01 00:00:00
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更新日期:1992-03-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2012-12-01 00:00:00
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更新日期:1991-12-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:1996-01-01 00:00:00
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更新日期:2016-08-01 00:00:00
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更新日期:2004-11-01 00:00:00
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journal_title:American journal of clinical pathology
pub_type: 杂志文章
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更新日期:1991-02-01 00:00:00
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journal_title:American journal of clinical pathology
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更新日期:1976-06-01 00:00:00
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更新日期:1994-06-01 00:00:00
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更新日期:1979-07-01 00:00:00
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更新日期:2011-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:2018-05-31 00:00:00
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journal_title:American journal of clinical pathology
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更新日期:1981-08-01 00:00:00
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journal_title:American journal of clinical pathology
pub_type: 杂志文章,评审
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更新日期:2009-08-01 00:00:00
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journal_title:American journal of clinical pathology
pub_type: 杂志文章,评审
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更新日期:1990-06-01 00:00:00
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journal_title:American journal of clinical pathology
pub_type: 杂志文章
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更新日期:1995-10-01 00:00:00
abstract::The JAK2(V617F)mutation is recurrent in polycythemia vera and essential thrombocythemia, which are myeloproliferative neoplasms frequently associated with arterial and venous thromboembolism. It has also been reported as a marker for occult myeloproliferative disorder (MPD) in patients with splanchnic venous thrombosi...
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更新日期:2010-07-01 00:00:00
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journal_title:American journal of clinical pathology
pub_type: 杂志文章
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更新日期:2012-08-01 00:00:00
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journal_title:American journal of clinical pathology
pub_type: 杂志文章
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更新日期:1982-03-01 00:00:00