Abstract：
:Typical yeast-phase cells of Blastomyces dermatitidis have a characteristic appearance in tissue sections. Fungal morphologic variation occurs infrequently in the lesions of blastomycosis, yet it can complicate the differential diagnosis, particularly if fresh tissue is not available for microbiologic culture. The authors report a case of pulmonary blastomycosis, confirmed by culture and direct immunofluorescence, in which some of the yeast-like cells were abnormally large. These giant yeast-like cells exceeded the size range accepted for the tissue forms of B. dermatitidis; therefore, coccidioidomycosis was considered initially in the differential diagnosis. Otherwise characteristic morphologic features of these cells, in particular multinucleation and the production of broad-based blastoconidia, helped resolve the differential diagnosis. The diagnosis can be confirmed by direct immunofluorescence or microbiologic culture.
journal_name
Am J Clin Patholjournal_title
American journal of clinical pathologyauthors
Watts JC,Chandler FW,Mihalov ML,Kammeyer PL,Armin ARdoi
10.1093/ajcp/93.4.575subject
Has Abstractpub_date
1990-04-01 00:00:00pages
575-8issue
4eissn
0002-9173issn
1943-7722journal_volume
93pub_type
杂志文章abstract：:Utilization of nonconventional bacterial strains and electron microscopy occasionally may aid in the recognition of unusual microorganisms which fail to be demonstrated by more conventional bacterial stains. We report an unusual case of recurrent vaginal polyps, initially thought by physical examination to represent a...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/79.5.637
更新日期：1983-05-01 00:00:00
abstract：:Suspensions of lymphoid cells from tissues have been used for the determination of the quantitative relationship between the T and B cell populations. The distribution of the lymphocytes within a given tissue, however, cannot be demonstrated once such a suspension has been prepared. Various methods of characterizing l...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/67.3.230
更新日期：1977-03-01 00:00:00
abstract：:Seven monoclonal antibodies of rat origin were generated against human epidermal keratins and were assayed by immunoblot and by immunoperoxidase staining of frozen sections from various human epithelial tissues. By immunoblotting, the antibodies recognized two different subsets of high molecular weight cytokeratin pol...
journal_title：American journal of clinical pathology
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更新日期：1988-03-01 00:00:00
abstract：OBJECTIVES:To explore the survival and definition of stage IA mixed endometrial carcinoma. METHODS:From June 1, 2010, to June 1, 2017, cases with stage IA endometrial cancer were included in this study. The survival outcomes were compared among patients with endometrioid (group A), nonendometrioid (group B), and mixed...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/aqz083
更新日期：2019-10-07 00:00:00
abstract：:Tissue specimens from a series of 46 hepatic tumors occurring in young female oral contraceptive users were tested for alpha1-antitrypsin deposition, utilizing immunocytochemical and histochemical methods. In two instances serum alpha1-antitrypsin phenotyping was also performed. Immunoreactive alpha1-antitrypsin depos...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/68.6.736
更新日期：1977-12-01 00:00:00
abstract：:We undertook a retrospective analysis of colonic spirochetosis in 14 cases: females, 3; males, 11; children, 4; adults, 10. Two men had HIV infections. All children and both HIV-infected men had abdominal complaints, diarrhea, or both. Most other adults underwent colonoscopy for polyp screening (n = 4) or follow-up of...
journal_title：American journal of clinical pathology
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更新日期：2003-12-01 00:00:00
abstract：:Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae are endemic in New York City hospitals and have been associated with serious infections globally. A real-time polymerase chain reaction (RT-PCR) assay was developed to detect carbapenem resistance attributable to KPC from blood culture bottles posi...
journal_title：American journal of clinical pathology
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更新日期：2012-04-01 00:00:00
abstract：:To establish the feasibility of immunotyping specimens transported over great distance, the University of Arizona and the Cleveland Clinic exchanged 39 lymphoma cases (26 B-cell, 13 T-cell cases) via air express for phenotyping. They were exchanged with the use of glass slides with adherent snap-frozen sections. The m...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/87.4.478
更新日期：1987-04-01 00:00:00
abstract：:To determine the current frequency of discovering important diagnoses at autopsy, the diagnoses made in all complete or "no head" autopsies during 1994 at a major tertiary care transplantation referral center were retrospectively compared with the diagnoses made antemortem. Of 176 autopsies, 79 (44.9%) revealed 1 or m...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/110.2.210
更新日期：1998-08-01 00:00:00
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journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/105.2.230
更新日期：1996-02-01 00:00:00
abstract：:Establishment of a procedure termed cerebrospinal fluid (CSF) TRAP ("Transport and Rapid Accessioning for Additional Procedures") allows clinicians to appropriately store, at -75 degrees C, and rapidly access CSF specimens. The CSF TRAP enhances patient care by decreasing the need for repeat lumbar punctures and provi...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/90.6.707
更新日期：1988-12-01 00:00:00
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journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：
更新日期：1976-07-01 00:00:00
abstract：:This study was undertaken to evaluate the precision and sensitivity of three different commercial APTT reagents containing the activators kaolin, micronized silica, or ellagic acid. These reagents varied greatly in their ability to detect mild coagulopathies. The ellagic acid reagent was able to detect the mildest def...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/82.4.436
更新日期：1984-10-01 00:00:00
abstract：OBJECTIVES:Millions of biospecimens will be collected during the coronavirus disease 2019 (COVID-19) pandemic. As learned from severe acute respiratory syndrome (SARS), proper biospecimen handling is necessary to prevent laboratory-related infections. METHODS:Centers for Disease Control and Prevention and World Health...
journal_title：American journal of clinical pathology
pub_type： 杂志文章,评审
doi：10.1093/ajcp/aqaa171
更新日期：2021-01-04 00:00:00
abstract：:The availability of automated anti-Xa heparin assays provides the opportunity to manage patient unfractionated heparin levels directly, rather than by the activated partial thromboplastin time. Because critically ill patients can acquire an antithrombin deficiency, we compared the performance of 3 anti-Xa heparin assa...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1309/8E3U7RXEPXNP27R7
更新日期：2006-09-01 00:00:00
abstract：:Three anti-Factor-VIII antibodies from hemophiliacs were reacted with samples of batches of Maws commerical bovine and porcine Factor VIII concentrates manufactured over a 12-year period. The apparent antibody concentrations varied widely with the different batches of concentrates. The variations are probably due to i...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/65.6.957
更新日期：1976-06-01 00:00:00
abstract：:A variant hemoglobin fraction may be an incidental finding during HbA(1c) analysis using the G8 Tosoh HPLC analyzer, but it is unclear if the retention times and fraction patterns can reliably predict the findings of a high-performance liquid chromatography (HPLC) β-thalassemia program (Bio Rad Variant II analyzer). W...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1309/AJCPJ0GSRWF0UBYT
更新日期：2012-09-01 00:00:00
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journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1309/NW194EAMD4WMEHJD
更新日期：2007-05-01 00:00:00
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journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/90.3.284
更新日期：1988-09-01 00:00:00
abstract：:A 65-year-old man with lower back pain was found to have multiple myeloma. Unique findings in the marrow aspirate smears of this patient were tadpolelike plasma cells and cellular rosettes simulating those seen in neuroblastoma. This case documents yet another facet of the broad morphologic spectrum of neoplastic plas...
journal_title：American journal of clinical pathology
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doi：10.1093/ajcp/98.6.630
更新日期：1992-12-01 00:00:00
abstract：:In this study, 2 patient populations, using different elution strategies, were compared to evaluate eluate yields under more and less restrictive conditions. An informative eluate was defined as one in which an antibody that could be clinically significant was detected in the eluate but was not detectable in the plasm...
journal_title：American journal of clinical pathology
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doi：10.1309/AJCPRVDCKI5CE2CH
更新日期：2011-09-01 00:00:00
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journal_title：American journal of clinical pathology
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doi：10.1093/ajcp/64.5.591
更新日期：1975-11-01 00:00:00
abstract：:Malignant B-cell lymphomas represent a heterogenous group of lymphoreticular disorders that involve the skin in about 20% of reported cases. Skin involvement may be primary or secondary (ie, the result of hematogenous spread). Primary cutaneous B-cell lymphomas (PCBCLs) are thought to take a comparatively favorable co...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/106.6.749
更新日期：1996-12-01 00:00:00
abstract：:A proportion of patients under surveillance for recurrent bladder carcinoma with no immediate evidence of bladder tumor recurrence have positive multitarget fluorescence in situ hybridization (FISH; UroVysion, Vysis, Downers Grove, IL) results. The course of these "anticipatory positive" cases and the time to bladder ...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1309/ADJL7E810U1H42BJ
更新日期：2007-02-01 00:00:00
abstract：:This report describes four siblings affected with familial intrahepatic cholestasis detected in early infancy. In the two male siblings, biliary cirrhosis and fatal hepatocellular carcinoma later developed, whereas the female siblings have had persistent hepatomegaly and recurrent episodes of cholestasis. Sequential b...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/76.2.172
更新日期：1981-08-01 00:00:00
abstract：:Cellular and humoral immunity combine to determine the outcome following exposure to hepatitis virus and are implicated in the proposed pathogenetic mechanism for acute and chronic hepatitis. Although antibody to HBsAg is found in virtually all following recovery from hepatitis B, a cell-mediated response to HBsAg can...
journal_title：American journal of clinical pathology
pub_type： 杂志文章,评审
doi：
更新日期：1976-05-01 00:00:00
abstract：:Recombinant factor VIIa (rFVIIa) has become available for treating people with hemophilia with inhibitors who experience bleeding or require surgery. It has become apparent that rFVIIa is useful in controlling bleeding in a variety of clinical situations. This review attempts to collate and summarize the nonhemophilia...
journal_title：American journal of clinical pathology
pub_type： 杂志文章,评审
doi：10.1309/D0G0-C96V-05CJ-5B4J
更新日期：2004-01-01 00:00:00
abstract：Objectives:To evaluate the prognostic values of microRNAs (miRNAs) in glioblastoma, and to see if there is an association between miRNAs and MGMT promoter methylation status. Methods:We collected paraffin blocks from resection specimens from 114 glioblastoma patients who had received temozolomide treatment and radioth...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/aqy008
更新日期：2018-03-29 00:00:00
abstract：:A 76-year-old white man previous diagnosed as having Waldenstrom's macroglobulinemia continued with persistent fevers and sweats for two and a half years. Recently, repeated automated differentials during 11 days of hospitalization failed to note any intracellular inclusions in the RBCs. Blood sent to the Microbiology...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/83.4.520
更新日期：1985-04-01 00:00:00
abstract：OBJECTIVES:GATA3 is a transcription factor regulating luminal cell differentiation in the mammary glands and has been implicated in the luminal types of breast carcinoma. The prognostic significance of GATA3 in breast cancer remains controversial. METHODS:In this study, we assessed the prognostic value of the molecule...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
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更新日期：2015-11-01 00:00:00
