Abstract：
:The hypothesis that glutamate is the afferent transmitter in the acoustico-lateralis receptors was examined in Plotosus electroreceptors. JSTX , a spider toxin known to specifically block glutamate receptors, irreversibly abolished afferent impulse discharges induced by iontophoretically applied glutamate, whereas those induced synaptically by focal stimulation of receptor cells were little affected. Such differential blocking effects by JSTX , complementary to other biochemical data, further provide pharmacological evidence against the glutamate hypothesis.
journal_name
Brain Resjournal_title
Brain researchauthors
Nagai T,Obara S,Kawai Ndoi
10.1016/0006-8993(84)91357-xsubject
Has Abstractpub_date
1984-05-21 00:00:00pages
183-7issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(84)91357-Xjournal_volume
300pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:We utilized nylon arrays to measure gene expression in mouse brains after various postmortem intervals (PMIs). Gene expression after overnight refrigeration or 4 h at room temperature then overnight refrigeration correlated highly and approximately equivalently to that in brains processed immediately. After 8-24 h at ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)02644-6
更新日期：2002-06-28 00:00:00
abstract：:Movement of fragmented DNA in dendrites of retinal neurons during the apoptotic cell death was investigated. The time-course of the movement of fragmented DNA in dendrites of retinal neurons undergoing apoptotic cell death induced by intravitreal N-methyl-d-aspartate (NMDA) injection were examined by in situ terminal ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.01.075
更新日期：2004-05-08 00:00:00
abstract：:We have examined the role of the octopamine-containing buccal OC interneuron in the fictive feeding rhythm generated by depolarizing a modulatory interneuron, SO, in the isolated central nervous system (CNS) of Lymnaea stagnalis. Before stimulating the SO, the initial fictive feeding rate was 2.0+/-0.37 bites/min (mea...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02968-1
更新日期：2000-12-22 00:00:00
abstract：:Sodium and potassium currents in the node of Ranvier decrease exponentially with time during long lasting voltage clamp experiments. This decline is strongly dependent on temperature (Q10 approximately 3). Thiamine and, particularly, its diand triphosphoric acid esters are shown to prevent this exponential decline of ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(75)90720-9
更新日期：1975-05-23 00:00:00
abstract：:The response of neurons in the preoptic and adjacent regions of the brain to intracarotid injection of hyperosmotic solutions was studied in 22 anesthetized cats. NaCl (0.5 M) caused a brisk acceleration of frequency lasting over 100 s in 120 of 207 units (58%). Glucose (2 M) and sucrose (2 M) had similar but smaller ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)91026-1
更新日期：1985-10-21 00:00:00
abstract：:Combined amylin+leptin (AMN+LEP) can reduce diet induced obesity and is very effective in combating LEP resistance. The purpose of this study was to evaluate the effect of AMN+LEP on central histaminergic signaling in lean and obese rats. Male rats were administered LEP (300 μg/kg/d), AMN (100 μg/kg/d), AMN+LEP or veh...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2011.12.022
更新日期：2012-03-09 00:00:00
abstract：:The so-called on- and off-cells of the rostral ventromedial medulla (RVM) send their axons to the spinal dorsal horn. Activation of on-cells precedes and coincides with a facilitation, and activation of off-cells coincides with an inhibition, of withdrawal reflexes elicited by noxious agents. Considerable evidence sup...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2018.02.025
更新日期：2018-05-01 00:00:00
abstract：:In order to explore the anatomical nature of the inhibitory GABAergic control of cerebral serotonergic neurons exerted at the level of the anterior raphé cells in the rat, we have studied the effect of GABA agonist agents (given systemically or infused locally into the raphé dorsalis or medianus) on cerebral 5-hydroxy...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90717-6
更新日期：1985-04-01 00:00:00
abstract：:Early brain injury (EBI) refers to the direct injury to the brain during the first 72 h after subarachnoid hemorrhage (SAH), which is one of the major causes for the poor clinical outcome after SAH. In this study, we investigated the effect and the related mechanism of Salvinorin A (SA), a selective kappa opioid recep...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2019.05.026
更新日期：2019-09-15 00:00:00
abstract：:Antisera against rat-liver S-adenosylhomocysteine hydrolase (SAH-hydrolase) and calf intestinal mucosal adenosine deaminase (ADA) were raised in rabbits and subsequently used to determine the distribution of the corresponding enzymes in rat-brain using the peroxidase-antiperoxidase immunohistochemical procedure. SAH-h...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90480-4
更新日期：1986-04-09 00:00:00
abstract：:It is known that transmitter release depends upon the entry of calcium ions into the synaptic terminal. Mitochondria have been suggested to play a key role on the regulation of intracellular Ca2+ concentration, thereby influencing transmitter liberation and synaptic transmission. Here we report the stimulatory effect ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)90618-6
更新日期：1980-01-13 00:00:00
abstract：:Echo-planar magnetic resonance imaging (EP-MRI), which is novel variant of MRI, is thought to have antidepressant properties in humans and animal models. Using the forced swimming test (FST), we investigated which monoaminergic system in mice is affected by EP-MRI. The short- and long-term effects of EP-MRI on immobil...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.08.011
更新日期：2008-10-21 00:00:00
abstract：:"Dystrophic' mice of the 129/ReJ-Dy strain have a genetic defect affecting Schwann cell proliferation. Spinal nerve roots of these animals contain myelinated and unmyelinated axons in addition to groups of large "amyelinated' axons. In affected regions of the spinal roots, myelinated axons are missing their myelin she...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)91116-1
更新日期：1981-11-09 00:00:00
abstract：:To elucidate the intracellular mechanism of the bursting activity which is characteristic of seizure discharge, the behavior of the intracellular cyclic nucleotide and the intracellular calcium during pentylenetetrazole (PTZ)-induced bursting activity in snail neurons was investigated. Cyclic AMP was increased about 3...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90137-3
更新日期：1983-06-20 00:00:00
abstract：:The divalent cation zinc has been reported to possess several physiological properties such as blocking apoptotic cell death through an inhibitory effect on Ca(2+)-Mg2+ endonuclease activity, or modulating the neurotoxicity via glutamate receptor subtypes. In the present study, we investigated the effect of peripheral...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(96)01112-2
更新日期：1996-12-16 00:00:00
abstract：:Our previous study revealed that, during tonic muscle contraction, remarkable functional differences among intrinsic and extrinsic muscles were observed during two different grip movements, i.e., precision and power grips. To verify whether this evidence is true even under the phasic muscle contraction, magnetic stimu...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)02368-5
更新日期：2002-05-03 00:00:00
abstract：:In rats, True Blue (or Granular Blue) was injected into the hippocampus of one hemisphere and Nuclear Yellow into a homotopic site of the hippocampus of the contralateral hemisphere. Following restricted injections into the septal part of area dentata fluorescent neurons were found in hilus fasciae dentate on both sid...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)90463-7
更新日期：1981-05-18 00:00:00
abstract：:A cyto- and myeloarchitectonic parcellation of the superior temporal sulcus and surrounding cortex in the rhesus monkey has been correlated with the pattern of afferent cortical connections from ipsilateral temporal, parietal and occipital lobes, studied by both silver impregnation and autoradiographic techniques. The...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(78)90584-x
更新日期：1978-06-23 00:00:00
abstract：:The effect of cerebellar stimulation on the accommodation of the lens was examined in anesthetized cats. An infrared optometer was used to measure the refractive power of the lens during stimulation of the cerebellum. The area giving responses within latencies shorter than 160 msec and amplitudes larger than 0.15 diop...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(78)90334-7
更新日期：1978-09-29 00:00:00
abstract：:Adiponectin (APN), a circulating adipose-derived hormone regulating inflammation and energy metabolism, has beneficial actions on cardio- and cerebrovascular disorders. Hypoadiponectinemia is associated with ischemic cerebrovascular disease, however, little is known about the cerebroprotective action of APN as well as...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.04.002
更新日期：2009-06-01 00:00:00
abstract：:Effects of phenytoin (PHT) on the intracellular calcium and intracellular protein changes during pentylenetetrazole (PTZ)-induced bursting activity in the neurons of the Japanese land snail Euhadra peliomphala were examined. In the examination with a computer controlled electron probe X-ray microanalyzer, PHT clearly ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)91510-0
更新日期：1985-02-18 00:00:00
abstract：:Inbred mouse strains differed significantly in sensitivity to convulsions induced by 9 convulsant drugs administered using a timed infusion procedure. Some strains (e.g. BALB/cJ, A/J) were generally seizure-susceptible, while some were generally seizure resistant (e.g. C57BL/6J, SWR/J). However, the overall pattern of...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90243-5
更新日期：1990-08-27 00:00:00
abstract：:Repeated odorant or electrical stimulation of the frog olfactory nerve leads to long-lasting reduction of excitability of the receptor neurons. In the turtle olfactory nerve electrical stimulation causes an increase in extracellular potassium concentration due to the efflux of potassium from active axons. Elevated pot...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90340-h
更新日期：1990-12-24 00:00:00
abstract：:Ischemic stroke is caused by the interruption of cerebral blood flow that leads to brain damage with long-term sensorimotor deficits. Stem cell transplantation may recover functional deficit by replacing damaged brain. In this study, we attempted to test whether the human neural stem cells (NSCs) can improve the outco...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.04.038
更新日期：2004-08-06 00:00:00
abstract：:Chemical (C) kindling by means of repeated spaced injections into the amygdala (AM) of a subconvulsive dose of L-glutamate and L-aspartate combined in a molar ratio of 1:3. (Glu/Asp) produced progressive seizure development culminating in generalized convulsion strikingly similar to electrically kindled Stage 5 seizur...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90481-1
更新日期：1987-11-03 00:00:00
abstract：:Trophic effects of neurturin, a member of the glial cell line-derived neurotrophic factor-family, have been demonstrated on mesencephalic dopaminergic neurons, suggesting its therapeutic potential for Parkinson's disease. This study was designed to test the neuroprotective and regenerative effects of an intrastriatal ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)02934-7
更新日期：2002-08-30 00:00:00
abstract：:The ventral tegmental area has been suggested as a possible site of action for the rewarding effect of opiates on the basis of the fact that local morphine injections in this but not other regions are rewarding. That this is a necessary and not just a sufficient site of opiate rewarding action was suggested by the fac...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)91232-5
更新日期：1983-01-03 00:00:00
abstract：:In rats under urethane, iontophoretic applications of GABA (30-60 nA) in the str. pyramidale of CA1, showed a rapidly fading inhibitory effect. By contrast, GABA had a well-maintained inhibitory effect in str. radiatum. During iontophoresis of nipecotic acid (30-85 nA) identical applications of GABA in str. pyramidale...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)91309-0
更新日期：1986-02-26 00:00:00
abstract：:Headache medicine is primarily dependent on patients' subjective reports of pain, which are assessed at diagnosis and throughout the duration of treatment. There is a need for an objective, quantitative biological measurement of headache pain severity. In this study, quantitative sensory testing (QST) was conducted vi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2012.12.043
更新日期：2013-03-01 00:00:00
abstract：:Concentrations of the neurotransmitters, serotonin (5-HT), dopamine (DA), and norepinephrine (NE) were measured in the developing rat brain at 12, 19, 26 and 42 days of age. The amino acid precursors, tryptophan (TRP) and tyrosine (TYR) were measured along with the 5-HT and DA metabolites, 5-hydroxyindoleacetic acid (...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(85)90146-4
更新日期：1985-01-01 00:00:00
