Pushing the signal hypothesis: what are the limits?

abstract：:ERM (ezrin/radixin/moesin) proteins, concentrated in actin rich cell-surface structures, cross-link actin filaments with the plasma membrane. They are involved in the formation of microvilli, cell-cell adhesion, maintenance of cell shape, cell motility and membrane trafficking. Recent analyses reveal that they are not...

journal_title：Biology of the cell

authors： Louvet-Vallée S

更新日期：2000-08-01 00:00:00

abstract：:Cells sense and respond to the biochemical and physical properties of the extracellular matrix (ECM) through adhesive structures that bridge the cell cytoskeleton and the surrounding environment. Integrin-mediated adhesions interact with specific ECM proteins and sense the rigidity of the substrate to trigger signalli...

journal_title：Biology of the cell

authors： Seetharaman S,Etienne-Manneville S

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND INFORMATION:Epithelial cadherin (E-cadherin) is involved in cell-cell adhesion through its extracellular domain, whereas the intracellular domain interacts with adaptor proteins, i.e. β-catenin, links E-cadherin to the actin cytoskeleton and participates in signal transduction events. E-cadherin protects mam...

journal_title：Biology of the cell

authors： Rosso M,Lapyckyj L,Amiano N,Besso MJ,Sánchez M,Chuluyan E,Vazquez-Levin MH

更新日期：2014-09-01 00:00:00

abstract：:Much remains to be learned about how cancer cells acquire the property of migration, a prerequisite for invasiveness and metastasis. Loss of p53 functions is assumed to be a crucial step in the development of many types of cancers, leading to dysregulation of cell cycle checkpoint controls and apoptosis. However, emer...

journal_title：Biology of the cell

authors： Roger L,Gadea G,Roux P

更新日期：2006-03-01 00:00:00

abstract：:This study was undertaken to evaluate the effects of caerulein, a CCK analog, on the different cell populations of the pancreatic tissue and their respective turnover. Rats received saline or caerulein subcutaneously and 3H-thymidine intraperitoneally three times a day for 4 days. They were sacrificed immediately afte...

journal_title：Biology of the cell

authors： Morisset J,Grondin G

更新日期：1989-01-01 00:00:00

abstract：:In the present study we report the occurrence of chaperonins, cpn10 and cpn60, in Chromatium vinosum and rat hepatocytes, using specific polyclonal antibodies in conjunction with the protein A-gold immunocytochemical technique. As demonstrated by quantitative evaluations, the immunolabeling for cpn10 and cpn60 in C vi...

journal_title：Biology of the cell

authors： Vélez-Granell CS,Arias AE,Torres-Ruíz JA,Bendayan M

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND INFORMATION:Proliferating cell nuclear antigen (PCNA) is a key component of the DNA replication machinery involved in the process of DNA elongation, recombination, methylation and repair. We have used PCNA fused with green fluorescent protein (GFP-PCNA) as a convenient tool to show the progress of S-phase in...

journal_title：Biology of the cell

authors： Kisielewska J,Lu P,Whitaker M

更新日期：2005-03-01 00:00:00

abstract：:The membrane content in phospholipids along the secretory pathway in rat pancreatic B-cells was studied in situ by high-resolution cytochemistry, applying the recently introduced phospholipase A2-gold technique. The gold particles were mostly associated with cell membranes, and the various types of membranes were labe...

journal_title：Biology of the cell

authors： Coulombe PA,Bendayan M

更新日期：1989-01-01 00:00:00

abstract：:The mammalian spermatozoa are endowed with a unique cytoskeleton which consists both of ubiquitous and specific proteins, some of them arising from gene haploid transcription. In the head, a dense perinuclear layer is made of basic proteins (calicin, cylicin, etc) associated with calmodulin and actin remnants. In the ...

journal_title：Biology of the cell

authors： Fouquet JP,Kann ML

更新日期：1994-01-01 00:00:00

abstract：:Previous experiments have revealed a relatively weak electrostatic binding capacity of in vitro reconstituted intermediate filaments (IFs) as well as of natural IFs of whole cell mount preparations for purified ribosomal particles of mammalian origin. In order to demonstrate that such associations also occur in vivo, ...

journal_title：Biology of the cell

authors： Traub P,Bauer C,Hartig R,Grüb S,Stahl J

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND INFORMATION:Nucleolin is a major nucleolar protein which is highly expressed in rapidly dividing cells and cancer cell lines. This protein is claimed to be multifunctional and could play a role in rRNA (ribosomal RNA) synthesis, as well as in cell division or response to cellular stresses. Therefore, how nuc...

journal_title：Biology of the cell

authors： Storck S,Thiry M,Bouvet P

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND INFORMATION:The rod outer segment (OS) is the specialised organelle where phototransduction takes place. Our previous proteomic and biochemical analyses on purified rod disks showed the functional expression of the respiratory chain complexes I-IV and F1 Fo -ATP synthase in OS disks, as well as active solubl...

journal_title：Biology of the cell

authors： Calzia D,Barabino S,Bianchini P,Garbarino G,Oneto M,Caicci F,Diaspro A,Tacchetti C,Manni L,Candiani S,Ravera S,Morelli A,Enrico Traverso C,Panfoli I

更新日期：2013-08-01 00:00:00

abstract：:Background information. In vitro-cultured microspores, after an appropriate stress treatment, can switch towards an embryogenic pathway. This process, known as microspore embryogenesis, is an important tool in plant breeding. Basic studies on this process in economically interesting crops, especially in recalcitrant p...

journal_title：Biology of the cell

authors： Bárány I,González-Melendi P,Fadón B,Mitykó J,Risueño MC,Testillano PS

更新日期：2005-09-01 00:00:00

abstract：:The influence of triiodothyronine (T3) on avian myoblast proliferation and differentiation was studied in secondary cultures using plating densities of 2,500 and 7,000 cells/cm2. Culture media were depleted of T3 (control myoblasts) and increasing amounts were then added to concentrations of 0.6, 3 and 15 nM T3 (treat...

journal_title：Biology of the cell

authors： Marchal S,Cassar-Malek I,Pons F,Wrutniak C,Cabello G

更新日期：1993-01-01 00:00:00

abstract：:The clonal rat rhabdomyosarcoma cell line BA-HAN-1C is composed of proliferating mononuclear cells, some of which spontaneously fuse to terminally differentiated myotube-like giant cells. This cell line has been shown to be susceptible to differentiation induction with all-trans retinoic acid (RA). Since it is still u...

journal_title：Biology of the cell

authors： Ramp U,Gerharz CD,Eifler E,Biesalski HK,Gabbert HE

更新日期：1994-01-01 00:00:00

abstract：:Revision of the reference map of the polytene chromosomes of Drosophila subobscura was started by means of the electron microscope. We present a map of regions 70B to 72D of the E chromosome obtained from squashed and thin-sectioned salivary glands. It was observed that the total number of bands in divisions 70B to 72...

journal_title：Biology of the cell

authors： Pérez-Alonso M,Cuenca JB,De Frutos R

更新日期：1988-01-01 00:00:00

abstract：:Extensive developmentally programmed DNA rearrangements, including thousands of internal deletions, occur in the differentiating somatic macronucleus in Tetrahymena thermophila. Some deletion systems involve the use of multiple alternative deletion sites. We report here the cloning and the sequences of three new alter...

journal_title：Biology of the cell

authors： Chau MF,Orias E

更新日期：1996-01-01 00:00:00

abstract：:Infection with Mycobacterium ulcerans results in a necrotising skin disease known as a Buruli ulcer, the pathology of which is directly linked to the bacterial production of the toxin mycolactone. Recent studies have identified the protein translocation machinery of the endoplasmic reticulum (ER) membrane as the prima...

journal_title：Biology of the cell

authors： Demangel C,High S

更新日期：2018-11-01 00:00:00

abstract：:Actin- and microtubule-based motors can propel different cargos along filaments. Within cells, they control the distribution of membrane-bound compartments by performing complementary tasks. Organelles make long journeys along microtubules, with class V myosins ensuring their capture and their dispersal in actin-rich ...

journal_title：Biology of the cell

authors： Desnos C,Huet S,Darchen F

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND INFORMATION:There are several reports indicating that starved fibroblasts show higher proliferation rates when re-fed with foetal bovine serum. We have evidence demonstrating that this phenomenon is related to secretory proteins which may be beneficial to wound healing. RESULTS:After re-feeding, 16 and 72 h...

journal_title：Biology of the cell

authors： Golpour M,Fattahi S,Niaki HA,Hadipoor A,Abedian Z,Ahangarian GR,Parsian H,Mosapour A,Khorasani HR,Vaziri HR,Bijani A,Mostafazadeh A

更新日期：2014-05-01 00:00:00

abstract：:Genome replication and assembly of viruses often takes place in specific intracellular compartments where viral components concentrate, thereby increasing the efficiency of the processes. For a number of viruses the formation of 'factories' has been described, which consist of perinuclear or cytoplasmic foci that most...

journal_title：Biology of the cell

authors： Novoa RR,Calderita G,Arranz R,Fontana J,Granzow H,Risco C

更新日期：2005-02-01 00:00:00

abstract：:We studied the behaviour in interphase and mitotic human cells of a 125 kDa (pI 6.5) antigen, associated with the nuclear matrix and detected in proliferating cells. Indirect immunofluorescence with a specific monoclonal antibody reveals that during interphase in WISH and Namalwa cells, as well as phytohaemagglutinin-...

journal_title：Biology of the cell

authors： Todorov IT,Philipova PN,Zhelev NZ,Hadjiolov AA

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND INFORMATION:Autofluorescence spectroscopy is a powerful tool for molecular histology and for following metabolic processes in biological samples as it does not require labelling. However, at the microscopic scale, it is mostly limited to visible and near infrared excitation of the samples. Several interestin...

journal_title：Biology of the cell

authors： Jamme F,Kascakova S,Villette S,Allouche F,Pallu S,Rouam V,Réfrégiers M

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND INFORMATION:The results of water permeability measurements suggest the presence of an AQP (aquaporin) in the membrane of the CV (contractile vacuole) in Amoeba proteus [Nishihara, Shimmen and Sonobe (2004) Cell Struct. Funct. 29, 85-90]. RESULTS:In the present study, we cloned an AQP gene from A. proteus [A...

journal_title：Biology of the cell

authors： Nishihara E,Yokota E,Tazaki A,Orii H,Katsuhara M,Kataoka K,Igarashi H,Moriyama Y,Shimmen T,Sonobe S

更新日期：2008-03-01 00:00:00

abstract：:Variant surface glycoprotein (VSG) of Trypanosoma brucei brucei AnTat 1.1 was released by means of the procedure described by Baltz et al. ([1976], Ann. Immunol. [Inst. Pasteur] 127C, 761-774). The concanavalin-A chromatography yielded 3 VSG fractions according to the addition, in the elution buffer, of alpha-methyl-D...

journal_title：Biology of the cell

authors： Boutignon F,Hublart M,Gomes V,Mendonca-Previato L,Tetaert D,Huet-Duvillier G,Degand P

更新日期：1988-01-01 00:00:00

abstract：:The ultrastructure of the Drosophila subobscura chromosome regions around the breakpoints of the complex E1 + 2 + 9 + 12 gene arrangement was analyzed. This overlapping inversion is formed by the association of the E1, E2, E9, and E12 simple inversions. Ultrastructure of sections involving 58D/59A, 61C/D, 62D/63A, 64B...

journal_title：Biology of the cell

authors： Cuenca JB,Saura AO,Sorsa V,de Frutos R

更新日期：1990-01-01 00:00:00

abstract：:Detection of nucleic acid sequence at the ultrastructural level has allowed us to better understand the expression of genes in some fields of application in cell biology. In situ hybridization at the ultrastructural level can be carried out using three different methods: on vibratome sections before embedding in epoxy...

journal_title：Biology of the cell

authors： Le Guellec D

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND INFORMATION:The BOR (branchio-oto-renal) syndrome is a dominant disorder most commonly caused by mutations in the EYA1 (Eyes Absent 1) gene. Symptoms commonly include deafness and renal anomalies. RESULTS:We have used the embryos of the frog Xenopus laevis as an animal model for early ear development to exa...

journal_title：Biology of the cell

authors： Li Y,Manaligod JM,Weeks DL

更新日期：2010-02-17 00:00:00

abstract：:Inside-out porcine thyroid follicles in culture undergo polarity reversal after being embedded in collagen gel. The newly-formed follicles reexpress some specific thyroid functions lost in inside-out follicles (Chambard et al., 1984. We present here an ultrastructural study of the inversion of polarity in this model s...

journal_title：Biology of the cell

authors： Barriere H,Chambard M,Mauchamp J,Gabrion J

更新日期：1986-01-01 00:00:00

abstract：:We have recently shown that staurosporine (ST) can trigger apoptosis of CaSki and HeLa cervical tumor cells from G2/M checkpoint, though the mechanism remains elusive. In this study, we reported that ST induced the inhibition of E6 and E7 viral oncogene and MDM2 expression, while it led to increased levels of p53, whi...

journal_title：Biology of the cell

authors： Bernard B,Prétet JL,Charlot JF,Mougin C

更新日期：2003-01-01 00:00:00