Conditional knockout of nucleolin in DT40 cells reveals the functional redundancy of its RNA-binding domains.

abstract：:A quantitative ultrastructural study was performed on 56 ejaculates showing anomalies of the sperm axonemal complex. The anomalies comprised either the absence of one, or more often several, axonemal structures, or defective elongation of the doublets. Several characteristics relating to the extent and superimposition...

journal_title：Biology of the cell

authors： Escalier D,David G

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND INFORMATION:The BOR (branchio-oto-renal) syndrome is a dominant disorder most commonly caused by mutations in the EYA1 (Eyes Absent 1) gene. Symptoms commonly include deafness and renal anomalies. RESULTS:We have used the embryos of the frog Xenopus laevis as an animal model for early ear development to exa...

journal_title：Biology of the cell

authors： Li Y,Manaligod JM,Weeks DL

更新日期：2010-02-17 00:00:00

abstract：:We used a high-resolution STEM to attempt to recognize the spatial localization of the macromolecular components of ribosomes isolated from Tetrahymena pyriformis. Images obtained either by the annular dark field detector or by the ratio-contrast mode (Z-contrast) show a ribosome as constituted of rounded dark areas, ...

journal_title：Biology of the cell

authors： Curgy JJ,Iftode F,Perasso R,André J,Mory C,Colliex C

更新日期：1984-01-01 00:00:00

abstract：:Recent advances in understanding the in vitro translocation of nascent polypeptides across the endoplasmic reticulum (ER) membrane have established a molecular basis for the initial reactions predicted by the signal hypothesis. The first two events involve a transient arrest of nascent chain elongation, followed by a ...

journal_title：Biology of the cell

authors： Hortsch M,Meyer DI

更新日期：1984-01-01 00:00:00

abstract：:Effect of estradiol-17 beta on rat vaginal epithelial cells (VEC) was studied by transmission electron microscopy. During the normal estrous cycle in adult rats keratinization and exfoliation of VEC was observed only in the estrus phase, though tonofilament bundles were seen distributed in the cytoplasm of the VEC dur...

journal_title：Biology of the cell

authors： Gupta PD,Vijayasaradhi S,Reddy AG

更新日期：1989-01-01 00:00:00

abstract：:The dynamics of change in mitochondria-rich (MR) cells density in the skin epithelium of Bufo viridis was studied on skin biopsies taken in vivo, throughout experimental periods lasting up to 3 months. When the bathing solution contained Cl-, MR cells' density (Dmrc) greatly decreased. There was one exception, when th...

journal_title：Biology of the cell

authors： Katz U,Gabby S

更新日期：1995-01-01 00:00:00

abstract：:Although much of eukaryotic cell biology is highly conserved, the most biomedically relevant organisms are often the most difficult or expensive to study. Non-vertebrate model organisms offer a practical and accessible alternative. Large collections of loss-of-function mutants have now been generated in the nematode C...

journal_title：Biology of the cell

authors： Haag ES

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND INFORMATION:Death receptors (DRs) induce intracellular signalling upon engagement of their cognate ligands, leading to apoptosis, cell survival or pro-inflammatory responses. In mammals, DR signalling is mediated by the recruitment of several DD (death domain)-containing molecules, such as FADD (Fas-associat...

journal_title：Biology of the cell

authors： Ishizawa YH,Tamura K,Yamaguchi T,Matsumoto K,Komiyama M,Takamatsu N,Shiba T,Ito M

更新日期：2006-08-01 00:00:00

abstract：:A history of the early development of the confocal laser scanning microscope in the MRC Laboratory of Molecular Biology in Cambridge is presented. The rapid uptake of this technology is explained by the wide use of fluorescence in the 80s. The key innovations were the scanning of the light beam over the specimen rathe...

journal_title：Biology of the cell

authors： Amos WB,White JG

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND INFORMATION:In eukaryotic cells, autophagy is considered a lysosomal catabolic process which participates in the degradation of intracellular components in a vacuolar structure termed autolysosome. This pathway plays a significant role in the erythropoiesis process, contributing to the clearance of some orga...

journal_title：Biology of the cell

authors： Fader CM,Salassa BN,Grosso RA,Vergara AN,Colombo MI

更新日期：2016-04-01 00:00:00

abstract：:The influence of triiodothyronine (T3) on avian myoblast proliferation and differentiation was studied in secondary cultures using plating densities of 2,500 and 7,000 cells/cm2. Culture media were depleted of T3 (control myoblasts) and increasing amounts were then added to concentrations of 0.6, 3 and 15 nM T3 (treat...

journal_title：Biology of the cell

authors： Marchal S,Cassar-Malek I,Pons F,Wrutniak C,Cabello G

更新日期：1993-01-01 00:00:00

abstract：:We have characterized the selectivity filter of the water channel aquaporin-1 (AQP1) of proximal straight tubules (PST), as an equivalent cylindrical structure with a diameter of approximately 4.5 A, where water molecules single file. We report here efforts to evaluate its length. PST were dissected from rabbit kidney...

journal_title：Biology of the cell

authors： Whittembury G,González E,Gutiérrez AM,Echevarría M,Hernández CS

更新日期：1997-08-01 00:00:00

abstract：:The sensory organs of the vertebrate head derive from two embryological structures, the neural crest and the ectodermal placodes. Although quite a lot is known about the secreted and transcription factors that regulate neural crest development, until recently little was known about the molecular pathways that regulate...

journal_title：Biology of the cell

authors： Brugmann SA,Moody SA

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND INFORMATION:The mitogen-inducible gene-6 (Mig-6) is a non-kinase scaffolding adaptor protein. It has been shown that Mig-6 may play important roles in regulating stress response, maintaining homeostasis and functioning as a tumour suppressor. In this study, we investigated the role of Mig-6 in cellular senes...

journal_title：Biology of the cell

authors： Xie B,Zhao L,Chen H,Jin B,Mao Z,Yao Z

更新日期：2013-10-01 00:00:00

abstract：:This study was undertaken to evaluate the effects of caerulein, a CCK analog, on the different cell populations of the pancreatic tissue and their respective turnover. Rats received saline or caerulein subcutaneously and 3H-thymidine intraperitoneally three times a day for 4 days. They were sacrificed immediately afte...

journal_title：Biology of the cell

authors： Morisset J,Grondin G

更新日期：1989-01-01 00:00:00

abstract：:The activation of M-phase promoting factor (MPF) in one-cell mouse embryo is independent from the nucleus. Other autonomous phenomena include the cortical activity observed at the end of the first cell cycle and the reorganization of the microtubule network. Here, we observed that the autonomous control of MPF activat...

journal_title：Biology of the cell

authors： Ciemerych MA,Tarkowski AK,Kubiak JZ

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND INFORMATION:ROS (reactive oxygen species) as well as components of the antioxidant redox systems may act as signals. To link acute environmental change with gene expression, changes in ROS and GSH/GSSG (reduced/oxidized glutathione) level were measured upon acute changes in temperature or oxygen availability...

journal_title：Biology of the cell

authors： Becker D,Brinkmann BF,Zeis B,Paul RJ

更新日期：2011-08-01 00:00:00

abstract：:Genome replication and assembly of viruses often takes place in specific intracellular compartments where viral components concentrate, thereby increasing the efficiency of the processes. For a number of viruses the formation of 'factories' has been described, which consist of perinuclear or cytoplasmic foci that most...

journal_title：Biology of the cell

authors： Novoa RR,Calderita G,Arranz R,Fontana J,Granzow H,Risco C

更新日期：2005-02-01 00:00:00

abstract：:Ultrastructural morphometry (point-counting method) was used to evaluate stereological parameters of rough endoplasmic reticulum (RER), Golgi complex, secretory granules, mitochondria and lysosomes of Rana ridibunda pituitary corticotropic (ACTH) cells in animals subjected to constant environmental conditions (CEC) in...

journal_title：Biology of the cell

authors： Gracia-Navarro F,Garcia-Navarro S,Garcia-Herdugo G

更新日期：1986-01-01 00:00:00

abstract：:For the purpose of investigating the nature of the nervous factor which controls cell proliferation in limb blastema of Newts, we have cultured primary mesenchymous cells from limb blastemas of Axolotl. The cultures were carried out in Petri dishes (Primaria, Falcon) with a basal medium with contained diluted MEM supp...

journal_title：Biology of the cell

authors： Albert P,Boilly B

更新日期：1986-01-01 00:00:00

abstract：:Rotation-mediated aggregate cultures of foetal rat liver cells were prepared and grown in a chemically defined medium. Their capacity for cellular organisation and maturation was studied over a culture period of 3 wk by using both morphologic and biochemical criteria. It was found that within each aggregate, distinct ...

journal_title：Biology of the cell

authors： Guigoz Y,Werffeli P,Favre D,Juillerat M,Wellinger R,Honegger P

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND INFORMATION:The costa is a prominent striated fibre that is found in protozoa of the Trichomonadidae family that present an undulating membrane. It is composed primarily of proteins that have not yet been explored. In this study, we used cell fractionation to obtain a highly enriched costa fraction whose str...

journal_title：Biology of the cell

authors： de Andrade Rosa I,Caruso MB,de Oliveira Santos E,Gonzaga L,Zingali RB,de Vasconcelos ATR,de Souza W,Benchimol M

更新日期：2017-06-01 00:00:00

abstract：:Regulated exocytosis of defensive secretory organelles, the trichocysts, as well as a transient Ca(2+)-influx can be induced in Paramecium by aminoethyldextran (Kerboeuf and Cohen, J Cell Biol (1990) 111, 2527). Knoll et al (Febs Lett (1992) 304, 265) reported that veratridine was also a secretagogue for Paramecium. H...

journal_title：Biology of the cell

authors： Kerboeuf D,Cohen J

更新日期：1996-01-01 00:00:00

abstract：:The development of a single, very large (25-35 microns diameter) nucleolus during oogenesis in the crustacean Acanthocyclops vernalis is described. The nucleolus is the site of ribosomal RNA production in the egg, as shown by in situ hybridization, and apparently the only source, as accessory cells are not observed. R...

journal_title：Biology of the cell

authors： Standiford DM

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND INFORMATION:Carcinoma of the oesophagus is the sixth leading cause of cancer death in the western world and is associated with a 5-year survival of less than 15%. Recent evidence suggests that stromal-epithelial interactions are fundamental in carcinogenesis. The advent of co-culture techniques permits the i...

journal_title：Biology of the cell

authors： Underwood TJ,Derouet MF,White MJ,Noble F,Moutasim KA,Smith E,Drew PA,Thomas GJ,Primrose JN,Blaydes JP

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Integrins are transmembrane alphabeta heterodimer receptors that function as structural and functional bridges between the cytoskeleton and ECM (extracellular matrix) molecules. The RGD (arginine-glycine-aspartate tripeptide motif)-dependent integrin alpha8beta1 has been shown to be involved in various cell ...

journal_title：Biology of the cell

authors： Benoit YD,Lussier C,Ducharme PA,Sivret S,Schnapp LM,Basora N,Beaulieu JF

更新日期：2009-09-14 00:00:00

abstract：BACKGROUND INFORMATION:The identification of a source of stem cells able to regenerate skeletal muscle was the goal of numerous studies with the aim to develop new therapeutic approaches for genetic muscle diseases or muscle injuries. A series of studies have demonstrated that stem cells derived from various tissues ma...

journal_title：Biology of the cell

authors： Dimicoli-Salazar S,Bulle F,Yacia A,Massé JM,Fichelson S,Vigon I

更新日期：2011-11-01 00:00:00

abstract：:Tensins are focal adhesion molecules that were identified and characterised in the late 1980s to early 1990s. They play an essential role in the control of cell adhesion. Tensins can bind the tail of ß integrin via their phospho tyrosine binding domain, they exhibit various protein interaction domains including a Src ...

journal_title：Biology of the cell

authors： Blangy A

更新日期：2017-03-01 00:00:00

abstract：:Acetylcholinesterase activity was detected in the carotid labyrinth of amphibians by both biochemical and histochemical methods. The histochemical tests showed enzyme activity in surfaces of afferent and efferent nerve terminals in contact with type I cells, but none within the type I cells. Acetylcholinesterase activ...

journal_title：Biology of the cell

authors： Poullet M,Verdiere M

更新日期：1985-01-01 00:00:00

abstract：:Apoptotic-like events could be rapidly induced by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) in cells of the mouse plasmacytoma cell line MPC-11 grown in serum-free medium. Indicators for apoptosis were morphological changes visualized by light and electron microscopy, such as chromatin condensation ...

journal_title：Biology of the cell

authors： Giese G,Schmidt J,Gilbert M,Albrecht R,Traub P

更新日期：1997-05-01 00:00:00