Induction and specification of the vertebrate ectodermal placodes: precursors of the cranial sensory organs.

Abstract:

:The sensory organs of the vertebrate head derive from two embryological structures, the neural crest and the ectodermal placodes. Although quite a lot is known about the secreted and transcription factors that regulate neural crest development, until recently little was known about the molecular pathways that regulate placode development. Herein we review recent findings on the induction and specification of the pre-placodal ectoderm, and the transcription factors that are involved in regulating placode fate and initial differentiation.

journal_name

Biol Cell

journal_title

Biology of the cell

authors

Brugmann SA,Moody SA

doi

10.1042/BC20040515

subject

Has Abstract

pub_date

2005-05-01 00:00:00

pages

303-19

issue

5

eissn

0248-4900

issn

1768-322X

pii

BC20040515

journal_volume

97

pub_type

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