Dial-a-mutant: web-based knockout collections for model organisms.

abstract：:After gradually moving away from preparation methods prone to artefacts such as plastic embedding and negative staining for cell sections and single particles, the field of cryo electron microscopy (cryo-EM) is now heading off at unprecedented speed towards high-resolution analysis of biological objects of various siz...

journal_title：Biology of the cell

authors： Orlov I,Myasnikov AG,Andronov L,Natchiar SK,Khatter H,Beinsteiner B,Ménétret JF,Hazemann I,Mohideen K,Tazibt K,Tabaroni R,Kratzat H,Djabeur N,Bruxelles T,Raivoniaina F,Pompeo LD,Torchy M,Billas I,Urzhumtsev A,Klahol

更新日期：2017-02-01 00:00:00

abstract：:Lentil seedlings were grown for 28 h in space, on board Spacelab (IML 1 Mission) and growth of the primary root was analysed. The length of cortical cells was less in near weightlessness than on the 1 g centrifuge (flight control) and mitotic index was lower but there was no apparent perturbation in the mitosis. To fu...

journal_title：Biology of the cell

authors： Driss-Ecole D,Schoevaert D,Noin M,Perbal G

更新日期：1994-01-01 00:00:00

abstract：:A series of analogs of vasopressin with photoreactive groups in positions 1, 2, 3, 4, 8 or 9 of the nonapeptide sequence have been studied for their effects on water and urea permeability of the isolated toad urinary bladder. Compounds with photoreactive groups in positions 3 or 8 bound covalently to receptors as judg...

journal_title：Biology of the cell

authors： Eggena P,Ma CL,Fahrenholz F,Buku A,Schwartz IL

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Integrins are transmembrane alphabeta heterodimer receptors that function as structural and functional bridges between the cytoskeleton and ECM (extracellular matrix) molecules. The RGD (arginine-glycine-aspartate tripeptide motif)-dependent integrin alpha8beta1 has been shown to be involved in various cell ...

journal_title：Biology of the cell

authors： Benoit YD,Lussier C,Ducharme PA,Sivret S,Schnapp LM,Basora N,Beaulieu JF

更新日期：2009-09-14 00:00:00

abstract：BACKGROUND INFORMATION:The role of the jelly coat that surrounds the amphibian oocytes has been widely discussed, but is poorly understood. The presence of the jelly coat is essential for fertilization. However, the structure and function of the molecules that comprise the jelly coat have not been thoroughly documented...

journal_title：Biology of the cell

authors： Krapf D,Vidal M,Arranz SE,Cabada MO

更新日期：2006-07-01 00:00:00

abstract：:Inside-out porcine thyroid follicles in culture undergo polarity reversal after being embedded in collagen gel. The newly-formed follicles reexpress some specific thyroid functions lost in inside-out follicles (Chambard et al., 1984. We present here an ultrastructural study of the inversion of polarity in this model s...

journal_title：Biology of the cell

authors： Barriere H,Chambard M,Mauchamp J,Gabrion J

更新日期：1986-01-01 00:00:00

abstract：:A general feature of the cell adhesion molecules belonging to the immunoglobulin family (Ig-CAMs) is to display a modular structure that provides a framework for multiple binding sites for other recognition molecules. Among this family, F3/contactin is a glycan phosphatidyl-inositol (GPI)-anchored molecule expressed b...

journal_title：Biology of the cell

authors： Falk J,Bonnon C,Girault JA,Faivre-Sarrailh C

更新日期：2002-10-01 00:00:00

abstract：:The oligochaete annelids, belonging to the subfamily Tubificinae, produce two types of spermatozoa: eusperm (the fertilising ones) and parasperm, protecting and carrying the eusperm. The pathway for the production of the two types is common until the onset of meiosis, but then a regular meiosis produces eusperm, where...

journal_title：Biology of the cell

authors： Ferraguti M,Fascio U,Boi S

更新日期：2002-05-01 00:00:00

abstract：:ERM (ezrin/radixin/moesin) proteins, concentrated in actin rich cell-surface structures, cross-link actin filaments with the plasma membrane. They are involved in the formation of microvilli, cell-cell adhesion, maintenance of cell shape, cell motility and membrane trafficking. Recent analyses reveal that they are not...

journal_title：Biology of the cell

authors： Louvet-Vallée S

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND INFORMATION:Human gingival tissues are prone to hyperplasia under inflammatory stimuli. We have identified gingival tissue-specific mesenchymal stem cells (GMSCs) and found their functional change being correlated with drug-induced gingival hyperplasia. However, whether these cells exhibit characteristics of...

journal_title：Biology of the cell

authors： Li N,Liu N,Zhou J,Tang L,Ding B,Duan Y,Jin Y

更新日期：2013-06-01 00:00:00

abstract：:I am pleased to contribute to this special issue of Biology of the Cell in honor of Yoshio Masui. Oocyte maturation remains a small enough and young enough field that the authors assembled for this issue can trace the entire development of the field over the last 30 years, beginning with the early demonstration by Mas...

journal_title：Biology of the cell

authors： Maller JL

更新日期：1998-10-01 00:00:00

abstract：:A monoclonal antibody of the IgG2a subclass was isolated from the supernate of a hybridoma line obtained with splenocytes from a mouse immunized with a crude nucleolar fraction of human Namalwa cells. This antibody identifies a single nuclear polypeptide antigen characterized by: (a) presence in proliferating human ce...

journal_title：Biology of the cell

authors： Philipova RN,Zhelev NZ,Todorov IT,Hadjiolov AA

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND INFORMATION:In eukaryotic cells, autophagy is considered a lysosomal catabolic process which participates in the degradation of intracellular components in a vacuolar structure termed autolysosome. This pathway plays a significant role in the erythropoiesis process, contributing to the clearance of some orga...

journal_title：Biology of the cell

authors： Fader CM,Salassa BN,Grosso RA,Vergara AN,Colombo MI

更新日期：2016-04-01 00:00:00

abstract：:Actin- and microtubule-based motors can propel different cargos along filaments. Within cells, they control the distribution of membrane-bound compartments by performing complementary tasks. Organelles make long journeys along microtubules, with class V myosins ensuring their capture and their dispersal in actin-rich ...

journal_title：Biology of the cell

authors： Desnos C,Huet S,Darchen F

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND INFORMATION:At fertilization in mammalian eggs, the sperm induces a series of Ca(2+) oscillations via the production of inositol 1,4,5-trisphosphate. Increased inositol 1,4,5-trisphosphate production appears to be triggered by a sperm-derived PLCzeta (phospholipase C-zeta) that enters the egg after gamete fu...

journal_title：Biology of the cell

authors： Yu Y,Halet G,Lai FA,Swann K

更新日期：2008-11-01 00:00:00

abstract：:LDs (lipid droplets) have long been considered as inert particles used by the cells to store fatty acids and sterols as esterified non-toxic lipid species (i.e. triacylglycerols and steryl esters). However, accumulating evidence suggests that LDs behave as a dynamic compartment, which is involved in the regulation of ...

journal_title：Biology of the cell

authors： Hapala I,Marza E,Ferreira T

更新日期：2011-06-01 00:00:00

abstract：:Since almost two decades, it is known that progesterone is responsible of the release of the prophase I arrest of amphibian oocytes and leads to the activation of the universal MPF, through a puzzling transduction pathway. It involves negative regulation of the cAMP-dependent protein kinase (PKA) and synthesis of new ...

journal_title：Biology of the cell

authors： Karaiskou A,Dupré A,Haccard O,Jessus C

更新日期：2001-09-01 00:00:00

abstract：:The dodecasatellite is a 11/12 bp tandemly repeated sequence which is overrepresented, with regard to its genomic representation, in extrachromosomal circular DNAs from D melanogaster embryos. Here we show that a bacterial plasmid carrying a cluster of dodecasatellite is not able to replicate efficiently in cultured c...

journal_title：Biology of the cell

authors： Renault S,Degroote F,Picard G

更新日期：1993-01-01 00:00:00

abstract：:Flow cytometry has important advantages over conventional techniques. It is rapid, highly sensitive and allows multi-parametric analysis and cell sorting. Potential exists for the measurement of many cell functions by flow cytometry. The technique can be used to determine cell viability, intracellular calcium and pH, ...

journal_title：Biology of the cell

authors： Maftah A,Huet O,Gallet PF,Ratinaud MH

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND INFORMATION:Available data concerning the sperm morphology of teleost fishes demonstrate wide variation. In the present study, the spermatozoa of Siberian sturgeon (Acipenser baerii Brandt, 1869), a chondrostean fish, was investigated. In contrast with teleost fish, chondrostean spermatozoa have a head with ...

journal_title：Biology of the cell

authors： Psenicka M,Alavi SM,Rodina M,Gela D,Nebesarova J,Linhart O

更新日期：2007-02-01 00:00:00

abstract：:Aspergillus fumigatus, the causative agent of human aspergillosis, binds to and degrades basement membrane laminin. Using immunoelectron microscopy, laminin binding appeared to be associated with the cell wall expansions of resting conidia, and progressively extended to the outer electron dense layer of the conidial w...

journal_title：Biology of the cell

authors： Tronchin G,Bouchara JP,Larcher G,Lissitzky JC,Chabasse D

更新日期：1993-01-01 00:00:00

abstract：:A quantitative ultrastructural study was performed on 56 ejaculates showing anomalies of the sperm axonemal complex. The anomalies comprised either the absence of one, or more often several, axonemal structures, or defective elongation of the doublets. Several characteristics relating to the extent and superimposition...

journal_title：Biology of the cell

authors： Escalier D,David G

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND INFORMATION:Proliferating cell nuclear antigen (PCNA) is a key component of the DNA replication machinery involved in the process of DNA elongation, recombination, methylation and repair. We have used PCNA fused with green fluorescent protein (GFP-PCNA) as a convenient tool to show the progress of S-phase in...

journal_title：Biology of the cell

authors： Kisielewska J,Lu P,Whitaker M

更新日期：2005-03-01 00:00:00

abstract：:Vertebrate embryos are able to reconstitute the body plan when early blastomeres are deleted, but it is not known whether this is accomplished by cells local to the lesion or by a readjustment of the entire pattern of the embryo. We distinguished between these two possibilities by studying which embryonic cells change...

journal_title：Biology of the cell

authors： Gallagher BC,Moody SA

更新日期：2004-09-01 00:00:00

abstract：:In 2001, with-no-lysine (WNK) kinases were identified as the genes responsible for the human hereditary hypertensive disease pseudohypoaldosteronism type II (PHAII). It took a further 6 years to clarify that WNK kinases participate in a signaling cascade with oxidative stress-responsive gene 1 (OSR1), Ste20-related pr...

journal_title：Biology of the cell

authors： Uchida S,Sohara E,Rai T,Sasaki S

更新日期：2014-02-01 00:00:00

abstract：:The micromeres, the first cells to be specified in sea urchin embryos, are generated by unequal cleavage at the fourth cell division. The micromeres differentiate autonomously to form spicules and dispatch signals to induce endomesoderm in the neighbouring macromeres cells in the embryo. Using a calcium indicator Fura...

journal_title：Biology of the cell

authors： Yazaki I,Abe M,Santella L,Koyama Y

更新日期：2004-03-01 00:00:00

abstract：:Netrins are secreted proteins that play a crucial role in neuronal migration and in axon guidance during the development of the nervous system. Netrin-1 has been shown to interact with the transmembrane receptors DCC and UNC5H and these receptors appeared of key importance in mediating the chemotropic activity of netr...

journal_title：Biology of the cell

authors： Mehlen P,Mazelin L

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND INFORMATION:Caspases are cysteine proteases that mediate apoptosis (programmed cell death) initiation and execution. Apoptosis is a conserved mechanism shared by all metazoans, although its physiological function and complexity show considerable taxon-dependent variations. To gain insight into the caspase re...

journal_title：Biology of the cell

authors： Weill M,Philips A,Chourrout D,Fort P

更新日期：2005-11-01 00:00:00

abstract：:Ultrastructural morphometry (point-counting method) was used to evaluate stereological parameters of rough endoplasmic reticulum (RER), Golgi complex, secretory granules, mitochondria and lysosomes of Rana ridibunda pituitary corticotropic (ACTH) cells in animals subjected to constant environmental conditions (CEC) in...

journal_title：Biology of the cell

authors： Gracia-Navarro F,Garcia-Navarro S,Garcia-Herdugo G

更新日期：1986-01-01 00:00:00

abstract：:Using gold labelled neoglycoproteins containing either alpha-D-glucose, N-acetyl-beta-D-glucosamine, alpha-D-mannose, 6-phospho-alpha-D-mannose, and alpha-L-fucose (BSA), we investigated their intranuclear binding sites in the TG human cell line. Although gold-labelled BSA did not give any noticeable labelling, the pr...

journal_title：Biology of the cell

authors： Bourgeois CA,Monsigny M

更新日期：1990-01-01 00:00:00