Polarity reversal of inside-out thyroid follicles cultured within collagen gel: an ultrastructural study.

abstract：:Much remains to be learned about how cancer cells acquire the property of migration, a prerequisite for invasiveness and metastasis. Loss of p53 functions is assumed to be a crucial step in the development of many types of cancers, leading to dysregulation of cell cycle checkpoint controls and apoptosis. However, emer...

journal_title：Biology of the cell

authors： Roger L,Gadea G,Roux P

更新日期：2006-03-01 00:00:00

abstract：:The water permeability of collecting ducts is greatly increased by the antidiuretic hormone, vasopressin (VP). Freeze-fracture studies were carried out to test if this permeability increase is associated with the appearance of intramembrane particle (IMP) aggregates and whether increased doses of VP lead to an increas...

journal_title：Biology of the cell

authors： Kubat B,Lorenzen M,Reale E

更新日期：1989-01-01 00:00:00

abstract：:Bovine tracheal gland (BTG) cells in culture show an epithelial-fibroblastoid transition after several passages. To investigate these BTG cell phenotype changes, we studied the effects of both the culture medium and passage number on the expression of epithelial cytoskeletal proteins and glandular serous cell markers....

journal_title：Biology of the cell

authors： Benali R,Dupuit F,Chevillard M,Jacquot J,Haye B,Puchelle E

更新日期：1991-01-01 00:00:00

abstract：:The mammalian spermatozoa are endowed with a unique cytoskeleton which consists both of ubiquitous and specific proteins, some of them arising from gene haploid transcription. In the head, a dense perinuclear layer is made of basic proteins (calicin, cylicin, etc) associated with calmodulin and actin remnants. In the ...

journal_title：Biology of the cell

authors： Fouquet JP,Kann ML

更新日期：1994-01-01 00:00:00

abstract：:The occurrence of the tubulin post-translational modification, polyglycylation, in stable microtubular structures was investigated during morphogenesis in two ciliates, Paramecium and Frontonia atra, belonging to the Epiplasmata group. This analysis was carried out by means of immunofluorescence and post-embedding imm...

journal_title：Biology of the cell

authors： Iftode F,Clérot JC,Levilliers N,Bré MH

更新日期：2000-12-01 00:00:00

abstract：:The pH-related change in morphology of vinblastine (VLB)-induced paracrystals formed in Chinese hamster ovary (CHO) cells was examined immunohistochemically in order to determine both the mechanism of tubulin crystallization and the influence of acidic pHs on cytoskeletal microtubules. Lowering the extracellular pH (p...

journal_title：Biology of the cell

authors： Takanari H,Morita J,Yamanaka H,Yada K,Takahashi A,Izutsu K

更新日期：1994-01-01 00:00:00

abstract：:A digitally-enhanced videomicroscopy study of rabbit gastric parietal cells in primary culture was performed using alternate observations with differential interference contrast and fluorescence optics of cells mounted and perfused on a temperature-controlled microscope stage. The effect of histamine, a physiological ...

journal_title：Biology of the cell

authors： Mangeat P,Gusdinar T,Sahuquet A,Hanzel DK,Forte JG,Magous R

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND INFORMATION:Caspases are cysteine proteases that mediate apoptosis (programmed cell death) initiation and execution. Apoptosis is a conserved mechanism shared by all metazoans, although its physiological function and complexity show considerable taxon-dependent variations. To gain insight into the caspase re...

journal_title：Biology of the cell

authors： Weill M,Philips A,Chourrout D,Fort P

更新日期：2005-11-01 00:00:00

abstract：:Co-isolated residual nuclear shells and residual nucleoli from membrane-depleted rat liver nuclei were spread according to Kleinschmidt's method. Comparison of the spread residual structures isolated from nuclear shells and spread pore complex-lamina isolated from nuclear envelopes showed that these residual structure...

journal_title：Biology of the cell

authors： Bureau J,Hubert J,Bouteille M

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Integrins are transmembrane alphabeta heterodimer receptors that function as structural and functional bridges between the cytoskeleton and ECM (extracellular matrix) molecules. The RGD (arginine-glycine-aspartate tripeptide motif)-dependent integrin alpha8beta1 has been shown to be involved in various cell ...

journal_title：Biology of the cell

authors： Benoit YD,Lussier C,Ducharme PA,Sivret S,Schnapp LM,Basora N,Beaulieu JF

更新日期：2009-09-14 00:00:00

abstract：:This review highlights new developments in miRNA as diagnostic and surveillance tools in diseases damaging the renal proximal tubule mediated by endothelin in the field of renal carcinoma, proteinuric kidney disease and tubulotoxicity. A new mechanism in the miRNA regulation of proteins leads to the binding of the miR...

journal_title：Biology of the cell

authors： Fries JWU

更新日期：2019-07-01 00:00:00

abstract：:Circulating glucocorticoid (GC) levels are thought to modulate the basal activity of pro-opiomelanocortin (POMC) neurons within the mediobasal hypothalamus (MBH) of the male rat. In a recent study we demonstrated that Fos-immunoreactivity (Fos-IR) was spontaneously induced throughout the dark phase of the light/dark c...

journal_title：Biology of the cell

authors： Jamali KA,Tramu G

更新日期：1997-12-01 00:00:00

abstract：:The clonal rat rhabdomyosarcoma cell line BA-HAN-1C is composed of proliferating mononuclear cells, some of which spontaneously fuse to terminally differentiated myotube-like giant cells. This cell line has been shown to be susceptible to differentiation induction with all-trans retinoic acid (RA). Since it is still u...

journal_title：Biology of the cell

authors： Ramp U,Gerharz CD,Eifler E,Biesalski HK,Gabbert HE

更新日期：1994-01-01 00:00:00

abstract：:The interaction of cells with extracellular matrix components contributes to their specific differentiation. We studied hepatic peroxisomes and their changing features during embryonic development, and we immunolocalized in the same tissue the extracellular matrix components laminin and collagen IV as well as the inte...

journal_title：Biology of the cell

authors： Depreter M,Nardacci R,Tytgat T,Espeel M,Stefanini S,Roels F

更新日期：1998-12-01 00:00:00

abstract：:Flow cytometry has important advantages over conventional techniques. It is rapid, highly sensitive and allows multi-parametric analysis and cell sorting. Potential exists for the measurement of many cell functions by flow cytometry. The technique can be used to determine cell viability, intracellular calcium and pH, ...

journal_title：Biology of the cell

authors： Maftah A,Huet O,Gallet PF,Ratinaud MH

更新日期：1993-01-01 00:00:00

abstract：:Regulated exocytosis of defensive secretory organelles, the trichocysts, as well as a transient Ca(2+)-influx can be induced in Paramecium by aminoethyldextran (Kerboeuf and Cohen, J Cell Biol (1990) 111, 2527). Knoll et al (Febs Lett (1992) 304, 265) reported that veratridine was also a secretagogue for Paramecium. H...

journal_title：Biology of the cell

authors： Kerboeuf D,Cohen J

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND INFORMATION:Cortactin contributes to growth cone morphogenesis by forming with dynamin, ring-shaped complexes that mechanically bundle and stabilise F-actin. However, the regulatory mechanism of cortactin action is poorly understood. RESULTS:Immunofluorescence microscopy revealed that protein kinase C (PKC)...

journal_title：Biology of the cell

authors： Yamada H,Kikuchi T,Masumoto T,Wei FY,Abe T,Takeda T,Nishiki T,Tomizawa K,Watanabe M,Matsui H,Takei K

更新日期：2015-09-01 00:00:00

abstract：:Changes in the organization of centrosomes in mouse splenic T lymphocytes stimulated by concanavalin A (con A) were examined by electron microscopy of serial sections. In both resting and stimulated lymphocytes the single centrosome consists of a pair of centrioles, satellite bodies, and pericentriolar material. In re...

journal_title：Biology of the cell

authors： Schweitzer I,Brown DL

更新日期：1984-01-01 00:00:00

abstract：:The microtubule-associated proteins MAPs 1 and 2 from pig brain have been found to react with antibodies directed against human ankyrin and spectrin, respectively (Bennett and Davis, 1981; Davis and Bennett, 1982). In a complementary approach we have prepared antibodies against MAP1 alpha. MAP1 gamma and MAP2 purified...

journal_title：Biology of the cell

authors： Hill AM,Cassoly R,Chetrite G,Pantaloni D

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND INFORMATION:The endometrial epithelial cell membrane is a key interface in female reproductive biology. Steroid hormones play a predominant role in cyclic changes which occur at this interface during the female menstrual cycle. Specific changes in the morphology of the endometrial epithelial cell surface bec...

journal_title：Biology of the cell

authors： Francis LW,Lewis PD,Gonzalez D,Ryder TA,Webb G,Joels LA,White JO,Wright CJ,Conlan RS

更新日期：2009-06-04 00:00:00

abstract：:LDs (lipid droplets) have long been considered as inert particles used by the cells to store fatty acids and sterols as esterified non-toxic lipid species (i.e. triacylglycerols and steryl esters). However, accumulating evidence suggests that LDs behave as a dynamic compartment, which is involved in the regulation of ...

journal_title：Biology of the cell

authors： Hapala I,Marza E,Ferreira T

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND INFORMATION:CLEM (correlative live cell and electron microscopy) seeks to bridge the data acquired with different imaging strategies, typically between light microscopy and electron microscopy. It has been successfully applied in cell cultures, although its use in multicellular systems is hampered by difficu...

journal_title：Biology of the cell

authors： Kolotuev I,Schwab Y,Labouesse M

更新日期：2009-12-04 00:00:00

abstract：:Xenopus oocytes were stained by anti-tubulin and anti-MAP1 antibodies during the first meiotic cell division. In the prophase-blocked oocytes, only few microtubules are present around the upper part of the nuclear envelope. These microtubules are resistant to cold, calcium and antimitotic drug treatments. At this stag...

journal_title：Biology of the cell

authors： Jessus C,Huchon D,Ozon R

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND INFORMATION:Continued advances in stem cell biology and stem cell transplantation rely on non-invasive biomarkers to characterise cells and stem cell aggregates. The non-invasive quality of such biomarkers is essential because exogenous labels, probes or reporters can unintentionally and dramatically alter s...

journal_title：Biology of the cell

authors： Buschke DG,Squirrell JM,Fong JJ,Eliceiri KW,Ogle BM

更新日期：2012-06-01 00:00:00

abstract：:Infection with Mycobacterium ulcerans results in a necrotising skin disease known as a Buruli ulcer, the pathology of which is directly linked to the bacterial production of the toxin mycolactone. Recent studies have identified the protein translocation machinery of the endoplasmic reticulum (ER) membrane as the prima...

journal_title：Biology of the cell

authors： Demangel C,High S

更新日期：2018-11-01 00:00:00

abstract：:ESCRTs (endosomal sorting complexes required for transport) were first discovered in yeast and are known to be required in the biogenesis of the MVB (multivesicular body). Most ESCRT research has been carried out in vitro using models such as yeast and mammalian cells in culture. The role of the ESCRTs genes in endoso...

journal_title：Biology of the cell

authors： Michelet X,Djeddi A,Legouis R

更新日期：2010-01-13 00:00:00

abstract：BACKGROUND INFORMATION:Caspase-dependent and -independent death mechanisms are involved in apoptosis in a variety of human carcinoma cells treated with antineoplastic compounds. Our laboratory has reported that p53 is a key contributor of mitochondrial apoptosis in cervical carcinoma cells after staurosporine exposure....

journal_title：Biology of the cell

authors： Nicolier M,Decrion-Barthod AZ,Launay S,Prétet JL,Mougin C

更新日期：2009-06-04 00:00:00

abstract：:The dodecasatellite is a 11/12 bp tandemly repeated sequence which is overrepresented, with regard to its genomic representation, in extrachromosomal circular DNAs from D melanogaster embryos. Here we show that a bacterial plasmid carrying a cluster of dodecasatellite is not able to replicate efficiently in cultured c...

journal_title：Biology of the cell

authors： Renault S,Degroote F,Picard G

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND INFORMATION:Autofluorescence spectroscopy is a powerful tool for molecular histology and for following metabolic processes in biological samples as it does not require labelling. However, at the microscopic scale, it is mostly limited to visible and near infrared excitation of the samples. Several interestin...

journal_title：Biology of the cell

authors： Jamme F,Kascakova S,Villette S,Allouche F,Pallu S,Rouam V,Réfrégiers M

更新日期：2013-07-01 00:00:00

abstract：:Apoptotic-like events could be rapidly induced by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) in cells of the mouse plasmacytoma cell line MPC-11 grown in serum-free medium. Indicators for apoptosis were morphological changes visualized by light and electron microscopy, such as chromatin condensation ...

journal_title：Biology of the cell

authors： Giese G,Schmidt J,Gilbert M,Albrecht R,Traub P

更新日期：1997-05-01 00:00:00