Abstract:
:In budding yeast, septins are involved in the morphogenesis checkpoint and the DNA damage checkpoint, both of which regulate cell-cycle progression. In this issue of Cell, Kremer et al. (2007) link septins to DNA damage in mammalian cells by identifying a new signaling pathway that includes the adaptors SOCS7 and NCK. As NCK controls actin dynamics, this pathway may connect DNA damage responses and cellular morphology in metazoans.
journal_name
Celljournal_title
Cellauthors
Kinoshita M,Takeda Sdoi
10.1016/j.cell.2007.08.022subject
Has Abstractpub_date
2007-09-07 00:00:00pages
777-9issue
5eissn
0092-8674issn
1097-4172pii
S0092-8674(07)01085-9journal_volume
130pub_type
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