Dancing with the host; flow-dependent bacterial adhesion.

Abstract:

:Most bacteria that colonize eukaryotes must bind directly to host cells to establish a replicative niche. In enteric bacteria, adhesion to host cells is often promoted by a lectin found on surface-localized pili. Some pili promote efficient adhesion only when they are subjected to shear stress, as found during the flow of blood over endothelium or mucous over the surface of the epithelium.

journal_name

Cell

journal_title

Cell

authors

Isberg RR,Barnes P

doi

10.1016/s0092-8674(02)00821-8

subject

Has Abstract

pub_date

2002-07-12 00:00:00

pages

1-4

issue

1

eissn

0092-8674

issn

1097-4172

pii

S0092867402008218

journal_volume

110

pub_type

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