Lipoid proteinosis with pseudomembranous conjunctivitis.

abstract：BACKGROUND:Antidrug antibodies (ADAs) may change pharmacokinetic or pharmacodynamic profiles of biologic therapies, potentially decreasing efficacy. OBJECTIVE:To evaluate the potential effects of brodalumab immunogenicity on safety, efficacy, and retreatment. METHODS:Data from 1 phase 2 and 3 phase 3 studies of broda...

journal_title：Journal of the American Academy of Dermatology

authors： Bagel J,Lebwohl M,Israel RJ,Jacobson A

更新日期：2020-02-01 00:00:00

abstract：:Primary hyperoxaluria encompasses 3 rare genetic disorders of glyoxylate metabolism characterized by excessive urinary excretion of oxalic acid, resulting in oxalosis. Patients typically have recurrent calcium oxalate nephrolithiasis and nephrocalcinosis, leading to chronic renal failure and death from uremia. Oxalate...

journal_title：Journal of the American Academy of Dermatology

authors： Marconi V,Mofid MZ,McCall C,Eckman I,Nousari HC

更新日期：2002-02-01 00:00:00

abstract：:We describe a 39-year-old man with a 3-year history of a recalcitrant psoriasiform eruption that was accentuated in the intertriginous areas. Hsitopathology was consistent with psoriasis. A glucagon level was 744 pg/mL with the upper limit of normal being 130 pg/mL. Computed tomographic scan of the abdomen revealed a ...

journal_title：Journal of the American Academy of Dermatology

authors： Johnson SM,Smoller BR,Lamps LW,Horn TD

更新日期：2003-08-01 00:00:00

abstract：:Atopic dermatitis is a chronic inflammatory skin disease that is frequently associated with respiratory allergies. Atopic dermatitis develops as a result of a complex interrelationship of environmental, immunologic, genetic, and pharmacologic factors. Efforts to understand the relative contributions of these factors h...

journal_title：Journal of the American Academy of Dermatology

authors： Leung DY,Soter NA

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:The reported prevalence and degrees of Demodex mite infestation in rosacea vary widely. OBJECTIVE:We sought to conduct an evidence-based meta-analysis of the prevalence and degrees of Demodex mite infestation in patients with rosacea. METHODS:Systematic literature review and meta-analysis were conducted. O...

journal_title：Journal of the American Academy of Dermatology

authors： Chang YS,Huang YC

更新日期：2017-09-01 00:00:00

abstract：:The case presented here involves a 32-year-old homosexual man with human immunodeficiency virus (HIV) seropositivity and unusual manifestations of secondary syphilis. The patient presented with syphilitic keratoderma and chorioretinitis, and his appearance superficially resembled that of a patient with Reiter's syndro...

journal_title：Journal of the American Academy of Dermatology

authors： Radolf JD,Kaplan RP

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:The focal facial dermal dysplasias (FFDD) are a genetically heterogeneous group of disorders characterized by congenital bilateral scarlike facial lesions, with or without associated facial anomalies. The cases have been reported under various names; thus the nosology is confusing and unclear. OBJECTIVE:Our...

journal_title：Journal of the American Academy of Dermatology

authors： Kowalski DC,Fenske NA

更新日期：1992-10-01 00:00:00

abstract：:A 38-year-old woman came for treatment of multiple clear vesicles and hemorrhagic papules on the posterior aspect of the right shoulder and the right axillary vault of 5 years' duration. These lesions would spontaneously manifest as clear or blood-filled vesicles (or both) and appear to be exacerbated by physical cont...

journal_title：Journal of the American Academy of Dermatology

authors： Bikowski JB,Dumont AM

更新日期：2005-09-01 00:00:00

abstract：:The antiphospholipid syndrome (APS) is an autoimmune disorder characterized by the occurrence of arterial and/or venous thromboembolic events and obstetric complications in the setting of circulating antiphospholipid antibodies. Dermatologic manifestations are commonly seen in APS with almost half of the patients exhi...

journal_title：Journal of the American Academy of Dermatology

authors： Kriseman YL,Nash JW,Hsu S

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:In infantile seborrheic dermatitis (ISD) several different pathogenetic mechanisms have been proposed. OBJECTIVE:The purpose of the study was to investigate the importance of essential fatty acids (EFAs) and their metabolites in the origin of ISD. METHODS:The serum EFA patterns of 30 children with ISD, 1 t...

journal_title：Journal of the American Academy of Dermatology

authors： Tollesson A,Frithz A,Berg A,Karlman G

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Treatment of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) has traditionally focused on minimizing recurrence and complication rates. However, the assessment of patient satisfaction and quality of life (QOL) is also important. These outcomes are best assessed by patient-reported outcome (PRO) ...

journal_title：Journal of the American Academy of Dermatology

authors： Lee EH,Klassen AF,Nehal KS,Cano SJ,Waters J,Pusic AL

更新日期：2013-08-01 00:00:00

abstract：:Patch testing is a necessary tool to investigate contact dermatitis, which has developed alongside the increased knowledge of contact sensitivity in the past 100 years. The history of patch testing, the current state of the art with its problems, and future prospects are discussed. ...

journal_title：Journal of the American Academy of Dermatology

authors： Hjorth N

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Noninvoluting congenital hemangioma (NICH) is a distinct vascular tumor of infancy. OBJECTIVE:We describe the clinical characteristics, histopathology, imaging, and natural history of NICH and compare our findings with previous reports. METHODS:We conducted a retrospective review of charts and photographic...

journal_title：Journal of the American Academy of Dermatology

authors： Lee PW,Frieden IJ,Streicher JL,McCalmont T,Haggstrom AN

更新日期：2014-05-01 00:00:00

abstract：:Cutaneous surgery has become critical to comprehensive dermatologic care, and dermatologists must therefore be equipped to manage the risks associated with surgical procedures. As complications may occur at any point along the continuum of care, assessing, managing and preventing risk from beginning to end becomes ess...

journal_title：Journal of the American Academy of Dermatology

authors： Strickler AG,Shah P,Bajaj S,Mizuguchi R,Nijhawan RI,Odueyungbo M,Rossi A,Ratner D

更新日期：2021-01-23 00:00:00

abstract：:Histoplasma capsulatum and Trichosporon inkin may cause disseminated disease in immunocompromised patients. Disseminated T inkin, the causative agent of white piedra, is rare and difficult to diagnose. We report the case of a 28 year-old man with newly diagnosed HIV infection who developed asymptomatic lesions on his ...

journal_title：Journal of the American Academy of Dermatology

authors： David C,Martin DB,Deng A,Cooper JZ

更新日期：2008-08-01 00:00:00

abstract：:Dacarbazine (DTIC-Dome) is a widely used chemotherapeutic agent employed in the therapy of malignant melanoma. In this communication, we present two patients who developed photosensitivity skin reactions immediately after its administration. Physicians using dacarbazine should be aware of this side effect and should i...

journal_title：Journal of the American Academy of Dermatology

authors： Yung CW,Winston EM,Lorincz AL

更新日期：1981-05-01 00:00:00

abstract：:A number of dermatologic conditions may have associated esophageal manifestations. Teleologically, this may be because both the skin and the esophagus are lined by stratified squamous epithelium. Bullous dermatoses that may produce blisters, erosions, and/or stricture of the esophagus include cicatricial pemphigoid, H...

journal_title：Journal of the American Academy of Dermatology

authors： Kaplan RP,Touloukian J,Ahmed AR,Newcomer VD

更新日期：1981-06-01 00:00:00

abstract：:Most clinicians agree that mycosis fungoides is the prototypic cutaneous T cell lymphoma. However, certain clinical characteristics indicate that this disorder may begin as a reactive rather than a neoplastic process. The concept of a nonneoplastic etiopathogenesis of mycosis fungoides is further supported by recent d...

journal_title：Journal of the American Academy of Dermatology

authors： Thiers BH

更新日期：1982-07-01 00:00:00

abstract：:Topical photodynamic therapy (PDT) is used to treat nonmelanoma skin cancers, such as actinic keratoses, Bowen's disease, and basal cell carcinoma (superficial and nodular). This article presents up-to-date, practical, evidence-based recommendations on the use of topical PDT using 5-aminolevulinic acid or methyl amino...

journal_title：Journal of the American Academy of Dermatology

authors： Braathen LR,Szeimies RM,Basset-Seguin N,Bissonnette R,Foley P,Pariser D,Roelandts R,Wennberg AM,Morton CA,International Society for Photodynamic Therapy in Dermatology.

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Ipilimumab is a human antibody that inhibits cytotoxic T-lymphocyte-associated antigen 4, leading to increases in T-cell activation and interleukin 2 secretion and has been approved for the treatment of advanced melanoma. Dermatologic adverse events such as rash, pruritus, and vitiligo have been reported in ...

journal_title：Journal of the American Academy of Dermatology

authors： Minkis K,Garden BC,Wu S,Pulitzer MP,Lacouture ME

更新日期：2013-09-01 00:00:00

abstract：:Granuloma annulare typically affects the hands and the feet, sparing the volar surfaces. A case of granuloma annulare localized to the palms is described. ...

journal_title：Journal of the American Academy of Dermatology

authors： Hsu S,Lehner AC,Chang JR

更新日期：1999-08-01 00:00:00

abstract：:The Americans With Disabilities Act (ADA) defines disability as a physical or mental impairment that substantially limits one or more major life activities. Although dermatology has received relatively little attention in the context of disability law, dermatologic diseases are properly covered by the ADA and are subj...

journal_title：Journal of the American Academy of Dermatology

authors： Curry ML,Curry JA,Cockerell CJ

更新日期：2002-12-01 00:00:00

abstract：:Anti-epiligrin cicatricial pemphigoid is an autoimmune subepithelial blistering disorder of mucous membranes and skin. By immunoblot analyses, sera of most patients with antiepiligrin cicatricial pemphigoid have been shown to react specifically with the alpha3 chain of laminin 5. We describe the first patient with ant...

journal_title：Journal of the American Academy of Dermatology

authors： Fujimoto W,Toi Y,Okazaki F,Lazarova Z,Yancey KB,Arata J

更新日期：1999-04-01 00:00:00

abstract：:A panel of antibodies reactive in routinely fixed, paraffin-embedded tissue sections was compared with a panel of antibodies reactive in frozen sections for the immunophenotyping of cutaneous lymphoproliferative disorders. Three T cell-associated markers (UCHL1, MT-1, MT-2, six B cell-associated markers (MB-1, MB-2, L...

journal_title：Journal of the American Academy of Dermatology

authors： Cerroni L,Smolle J,Soyer HP,Martinez Aparicio A,Kerl H

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Gorlin-Goltz syndrome (GGS) is an autosomal-dominant disease characterized by the early onset of multiple basal cell carcinomas (BCCs), among other findings. Clinically, the BCCs may appear as soft pedunculated neoplasms that can be mistaken for true acrochordons. OBJECTIVE:We sought to describe the dermato...

journal_title：Journal of the American Academy of Dermatology

authors： Feito-Rodríguez M,Sendagorta-Cudós E,Moratinos-Martínez M,González-Beato MJ,de Lucas-Laguna R,Pizarro A

更新日期：2009-05-01 00:00:00

abstract：:Mastocytosis is a disease in which the mast cell population is increased in various tissues. Although the mechanism for the increased density of mast cells is not understood, recent research into mast cell structure and function has improved our understanding of the symptomatology and prompted newer and better approac...

journal_title：Journal of the American Academy of Dermatology

authors： DiBacco RS,DeLeo VA

更新日期：1982-12-01 00:00:00

abstract：BACKGROUND:B-cell chronic lymphocytic leukemia (B-CLL) is a low-grade lymphoproliferative disorder with characteristic histomorphologic features and an identifiable immunophenotype. The skin can be involved in the context of known disease, but cutaneous signs are rarely the presenting findings. OBJECTIVE:Evaluation of...

journal_title：Journal of the American Academy of Dermatology

authors： Plaza JA,Comfere NI,Gibson LE,Colgan M,Davis DM,Pittelkow MR,Colgan JP

更新日期：2009-05-01 00:00:00

abstract：:Twenty-six lymph node biopsy specimens from twenty-three patients with Sézary syndrome were microscopically evaluated and compared with nodal specimens from six patients with pre-Sézary syndrome and four control patients with dermatopathic lymphadenopathy. Three phases of nodal involvement by cerebriform lymphocytes w...

journal_title：Journal of the American Academy of Dermatology

authors： Buzzanga J,Banks PM,Winkelmann RK

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Onychomycosis is a common nail infection, often resulting in nail plate damage and deformity. Topical lacquer treatments have negligible efficacy. Oral treatments, although more efficacious, are limited by drug interactions and potential hepatotoxicity. OBJECTIVE:We investigated the safety and efficacy of e...

journal_title：Journal of the American Academy of Dermatology

authors： Elewski BE,Rich P,Pollak R,Pariser DM,Watanabe S,Senda H,Ieda C,Smith K,Pillai R,Ramakrishna T,Olin JT

更新日期：2013-04-01 00:00:00

abstract：:We studied 20 Caucasian middle-aged patients, mostly women, who had asymptomatic, gray-brown patches with geographic borders, occasionally interspersed with hypopigmented macules, on the dorsum of the forearms, mostly bilaterally. The distal aspect of the arms was also involved in 2 patients; the face was always spare...

journal_title：Journal of the American Academy of Dermatology

authors： Rongioletti F,Rebora A

更新日期：2000-04-01 00:00:00