The development of the patch testing procedure and working for consistency.

abstract：BACKGROUND:Topical corticosteroids alone or in combination with other therapies are widely used to treat mycosis fungoides (MF), but data on response rates to their use as monotherapy in MF are limited. OBJECTIVE:To evaluate the efficacy of topical corticosteroid monotherapy in MF; compare sex, age, stage distribution...

journal_title：Journal of the American Academy of Dermatology

authors： Kartan S,Shalabi D,O'Donnell M,Alpdogan SO,Sahu J,Shi W,Porcu P,Cha J,Nikbakht N

更新日期：2020-05-16 00:00:00

abstract：:Sixty-six confirmed cases of Bowen's disease (intraepidermal squamous cell carcinoma) were seen from 1965 through 1976: twenty-four cases were treated surgically-four by excision (two recurrences) and twenty by desiccation and curettage (four recurrences); one was treated with x-ray radiation; and forty-one were treat...

journal_title：Journal of the American Academy of Dermatology

authors： Sturm HM

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND:For persons of childbearing potential prescribed isotretinoin, the iPLEDGE program requires use of 2 simultaneous methods of contraception or commitment to abstinence. OBJECTIVE:To model the relative effectiveness of a variety of contraception strategies for patients taking isotretinoin, including those tha...

journal_title：Journal of the American Academy of Dermatology

authors： Barbieri JS,Roe AH,Mostaghimi A

更新日期：2020-07-01 00:00:00

abstract：:The standard definition of itching (as "an unpleasant sensation that provokes the desire to scratch") takes no account of recent advances in knowledge about itch physiology. Always imprecise, this definition is also out-of-date. Its defects are discussed in this article, and some modifications are proposed. ...

journal_title：Journal of the American Academy of Dermatology

authors： Savin JA

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:There are subgroups of cutaneous squamous cell carcinoma (SCC) that have a higher risk for both regional and distant metastasis. When cutaneous SCC does metastasize, it typically spreads first to local nodal groups. Sentinel lymph node (SLN) localization has been successfully used to evaluate nodal metastasi...

journal_title：Journal of the American Academy of Dermatology

authors： Weisberg NK,Bertagnolli MM,Becker DS

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Surgeons use absorbable and nonabsorbable sutures for epidermal wound closure. No large, randomized studies have compared the effect of these suture types on facial scar appearance. OBJECTIVE:To assess postsurgical facial scar appearance using either rapidly absorbable polyglactin 910 or nylon for epidermal...

journal_title：Journal of the American Academy of Dermatology

authors： Moran B,Humphrey S,Seal A,Berkowitz J,Zloty D

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Several studies have found that the microbiota of psoriatic lesions is different from that of healthy skin. OBJECTIVE:To characterize the microbiota of lesional and unaffected skin in patients with psoriasis and controls and investigate the correlation between cutaneous microbiota and clinical features of p...

journal_title：Journal of the American Academy of Dermatology

authors： Quan C,Chen XY,Li X,Xue F,Chen LH,Liu N,Wang B,Wang LQ,Wang XP,Yang H,Zheng J

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Acne is one of the most common concerns of patients with body dysmorphic disorder (BDD), a psychiatric condition defined as a preoccupation with a slight or imagined defect in appearance that causes significant disruption in daily functioning. OBJECTIVE:We sought to screen for BDD symptoms among patients wi...

journal_title：Journal of the American Academy of Dermatology

authors： Bowe WP,Leyden JJ,Crerand CE,Sarwer DB,Margolis DJ

更新日期：2007-08-01 00:00:00

abstract：:Erythropoietic protoporphyria is an inherited disorder characterized biochemically by a deficiency of ferrochelatase, the enzyme that catalyzes the incorporation of ferrous iron into protoporphyrin to form heme. We describe a patient who illustrates the unpredictability of the course of liver disease in erythropoietic...

journal_title：Journal of the American Academy of Dermatology

authors： Mercurio MG,Prince G,Weber FL Jr,Jacobs G,Zaim MT,Bickers DR

更新日期：1993-11-01 00:00:00

abstract：:Hutchinson's sign, periungual extension of brown-black pigmentation from longitudinal melanonychia onto the proximal and lateral nailfolds, is an important indicator of subungual melanoma. However, experience has demonstrated that Hutchinson's sign, although valuable, is not an infallible predictor of melanoma. Periun...

journal_title：Journal of the American Academy of Dermatology

authors： Baran R,Kechijian P

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Hidradenitis suppurativa (HS) is a chronic inflammatory disease involving intertriginous skin. Previous epidemiologic studies have been limited by small sample size. OBJECTIVE:We sought to describe the prevalence and comorbidities of HS in a large patient care database. METHODS:In this retrospective case-c...

journal_title：Journal of the American Academy of Dermatology

authors： Shlyankevich J,Chen AJ,Kim GE,Kimball AB

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Melanoma patients with negative nodes after sentinel lymph node biopsy are a heterogeneous group. Current guidelines fail to adequately stratify surveillance and treatment for this group. Also, there is scarce data on adjuvant treatments for these patients. OBJECTIVE:To create a nomogram including clinical ...

journal_title：Journal of the American Academy of Dermatology

authors： Bertolli E,de Macedo MP,Calsavara VF,Pinto CAL,Duprat Neto JP

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Women with stage I malignant melanoma (MM) have a survival advantage over men as judged by univariate analysis. However, on multivariate analysis, gender was found to be an independent predictor of survival in only 8 of 14 published studies. OBJECTIVE:This study attempts to explain the disparate findings fo...

journal_title：Journal of the American Academy of Dermatology

authors： Vossaert KA,Silverman MK,Kopf AW,Bart RS,Rigel DS,Friedman RJ,Levenstein M

更新日期：1992-03-01 00:00:00

abstract：:In vivo, topical minoxidil therapy is associated with changes in the follicular epithelium, tissue and blood lymphocyte populations, lymphocyte blastogenic response to mitogens, and perifollicular vasculature. Biopsy specimens taken from areas of terminal hair regrowth show a dose-dependent increase in hair follicle l...

journal_title：Journal of the American Academy of Dermatology

authors： Fiedler-Weiss VC

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:Melanoma is the most lethal form of skin cancer. Diagnosis of amelanotic melanoma and detection of micrometastases in sentinel lymph nodes pose diagnostic and therapeutic dilemmas for the dermatopathologist and clinician. OBJECTIVE:The purpose of this article is to determine the utility of immunohistochemis...

journal_title：Journal of the American Academy of Dermatology

authors： O'Reilly FM,Brat DJ,McAlpine BE,Grossniklaus HE,Folpe AL,Arbiser JL

更新日期：2001-09-01 00:00:00

abstract：:The early experiments of Marion B. Sulzberger suggested that the skin played a vital role in the generation of allergic contact dermatitis and other delayed type hypersensitivity reactions. This lecture is presented in the historical context of Dr. Sulzberger's lifework and interest in mechanisms involved in delayed t...

journal_title：Journal of the American Academy of Dermatology

authors： Katz SI

更新日期：1985-09-01 00:00:00

abstract：:Melanocytic nevi are commonly believed to undergo changes during pregnancy. This is probably related to hormonal influences; however, few studies have been able to prove it. We observed a case of a benign melanocytic nevus, which showed significant enlargement during pregnancy and immediate postpartum regression assoc...

journal_title：Journal of the American Academy of Dermatology

authors： Lee HJ,Ha SJ,Lee SJ,Kim JW

更新日期：2000-05-01 00:00:00

abstract：:A 65-year-old man with insulin-dependent diabetes developed intractable pruritus preceding weight loss and increasing fatiguability. Esophagogastroduodenoscopy revealed infection with Candida, cytomegalovirus, and Cryptosporidium. His T cell helper/suppressor ratio was inverted, and the serum human immunodeficiency vi...

journal_title：Journal of the American Academy of Dermatology

authors： Shapiro RS,Samorodin C,Hood AF

更新日期：1987-05-01 00:00:00

abstract：:Cryosurgery is a commonly used modality for treatment of benign and malignant lesions in dermatology. Although cryosurgery has been used for treatment of actinic keratoses, to our knowledge there have been no published reports on actual cure rates. This article presents a cryosurgical technic for treatment of actinic ...

journal_title：Journal of the American Academy of Dermatology

authors： Lubritz RR,Smolewski SA

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND:There is controversy regarding a potential increased risk of lymphoma in patients with atopic dermatitis (AD). OBJECTIVE:To assess the risk of lymphoma and the role of topical treatments in patients with AD. METHODS:A systematic literature search and a separate meta-analysis were performed on case control ...

journal_title：Journal of the American Academy of Dermatology

authors： Legendre L,Barnetche T,Mazereeuw-Hautier J,Meyer N,Murrell D,Paul C

更新日期：2015-06-01 00:00:00

abstract：:Angiosarcoma that develops in areas of chronic lymphedema is also called Stewart-Treves syndrome. It usually appears in areas of lymphedema several years after mastectomy for breast carcinoma. Only 10% of these angiosarcomas occur in areas of chronic lymphedema as a result of another cause. We present a patient with e...

journal_title：Journal of the American Academy of Dermatology

authors： Hallel-Halevy D,Yerushalmi J,Grunwald MH,Avinoach I,Halevy S

更新日期：1999-08-01 00:00:00

abstract：:The most common active ingredient in hair coloring is para-phenylenediamine (PPDA), which can produce contact dermatitis, particularly in persons who dye their scalp hair and in hairdressers. We have identified another group of patients also at risk, namely men from Arab countries, who commonly grow beards and dye the...

journal_title：Journal of the American Academy of Dermatology

authors： Hsu TS,Davis MD,el-Azhary R,Corbett JF,Gibson LE

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Detecting a more advanced stage of the primary melanoma after wide local excision and reconstruction can complicate patient counseling about prognosis, management of surgical margins, and indications for sentinel lymph node biopsy. OBJECTIVE:To identify the frequency of and risk factors associated with upst...

journal_title：Journal of the American Academy of Dermatology

authors： Etzkorn JR,Sharkey JM,Grunyk JW,Shin TM,Sobanko JF,Miller CJ

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Methotrexate has been used both as monotherapy and as an adjunct to corticosteroids in the treatment of alopecia areata (AA), though there exists a paucity of definitive evidence and guidelines in this setting. OBJECTIVES:To 1) determine the efficacy and risks associated with methotrexate therapy for AA, 2)...

journal_title：Journal of the American Academy of Dermatology

authors： Phan K,Ramachandran V,Sebaratnam DF

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Vulvar lichen sclerosus is a chronic condition usually responsive to topical corticosteroids. OBJECTIVE:We sought to evaluate the efficacy (reduction of signs and symptoms) and safety of clobetasol propionate 0.05% and tacrolimus 0.1% in the treatment of vulvar lichen sclerosus. METHOD:This double-blind, r...

journal_title：Journal of the American Academy of Dermatology

authors： Funaro D,Lovett A,Leroux N,Powell J

更新日期：2014-07-01 00:00:00

abstract：:Livedo reticularis (LR) is a well-known, relatively common physical finding consisting of macular, violaceous, connecting rings that form a netlike pattern (Fig 1). In most cases, it is a completely benign finding related to cold exposure. However, there are many potential causes (Table I), and this can make the evalu...

journal_title：Journal of the American Academy of Dermatology

authors： Gibbs MB,English JC 3rd,Zirwas MJ

更新日期：2005-06-01 00:00:00

abstract：:A 43-year-old man with ulcerous granulomatous cheilitis and submaxillary lymph node invasion caused by Scopulariopsis brevicaulis infection is described. Administration of itraconazole produced a dramatic and definitive cure. Reported cases of deep mycosis caused by S. brevicaulis infection are also reviewed. ...

journal_title：Journal of the American Academy of Dermatology

authors： Creus L,Umbert P,Torres-Rodríguez JM,López-Gil F

更新日期：1994-11-01 00:00:00

abstract：:During 1 year of continuous suppressive therapy for frequent recurrent genital herpes, about 44% of patients taking 400 mg acyclovir twice a day had no recurrences and 4% of patients taking placebo had no recurrences (i.e., fewer patients taking acyclovir had recurrences, and when they did there were fewer recurrences...

journal_title：Journal of the American Academy of Dermatology

authors： Conant MA

更新日期：1988-01-01 00:00:00

abstract：:More than 100,000 species of fungi have been identified worldwide, but only a few dozen are of medical significance. Because of the opportunistic nature of these organisms and the prevalence of immunodeficient conditions, the number of medically important fungi is increasing. Identification of the causative organism i...

journal_title：Journal of the American Academy of Dermatology

authors： Elewski BE,Hazen PG

更新日期：1989-10-01 00:00:00

abstract：:Cutaneous fungal infections are a major source of morbidity in HIV-infected patients, and their management poses special challenges. Superficial mycoses, such as tinea pedis, tinea cruris, tinea corporis, and onychomycosis, are no more common in HIV-infected patients than in the HIV-negative population but are of grea...

journal_title：Journal of the American Academy of Dermatology

authors： Elmets CA

更新日期：1994-09-01 00:00:00