Rescue of a Sendai virus DI genome by other parainfluenza viruses: implications for genome replication.

abstract：:It has recently been shown that RNA from the bottom component of cowpea mosaic virus is capable of self-replication in cowpea mesophyll protoplasts, providing a tool for the investigation of the contribution of each RNA strand toward viral multiplication. Evidence is presented here, using this system, to show that the...

journal_title：Virology

authors： Stanley J,Goldbach R,Van Kammen A

更新日期：1980-10-15 00:00:00

abstract：:Wild-type vaccinia virus WR strain forms non-fusogenic (F-) large plaques and is hemagglutinin positive (HA+) under normal conditions of virus infection. We have analyzed a collection of spontaneous, highly attenuated mutants of vaccinia virus isolated from persistently infected Friend erythroleukemia cells (E. Paez, ...

journal_title：Virology

authors： Ortiz MA,Paez E

更新日期：1994-01-01 00:00:00

abstract：:The human immunodeficiency virus (HIV-1) causes various hematopoietic abnormalities, with thrombocytopenia (TP) occurring in 30% of infected individuals. In the present study, we aimed to determine whether HIV-1 in the bone marrow of TP patients can infect primary megakaryocytes in vitro, which may contribute to the d...

journal_title：Virology

authors： Voulgaropoulou F,Pontow SE,Ratner L

更新日期：2000-03-30 00:00:00

abstract：:Successful HIV-1 infection requires a number of specific stages leading to integration of the provirus. We previously suggested that members of the VPAC neuroendocrine receptor family may play a role in HIV-1 infection. We now show that stimulation of the VPAC2 receptor with specific agonists provides strong resistanc...

journal_title：Virology

authors： Bokaei PB,Ma XZ,Sakac D,Branch DR

更新日期：2007-05-25 00:00:00

abstract：:The expression of type I murine interferon (MuIFN) genes and several other cellular genes was examined in poly rI.rC induced and Newcastle disease virus (NDV) infected mouse cells. Northern analysis of RNA from induced L cells revealed that the MuIFN-alpha s are expressed efficiently in NDV infected cells but only at ...

journal_title：Virology

authors： Kelley KA,Pitha PM

更新日期：1985-12-01 00:00:00

abstract：:We have investigated the role of vif in maedi-visna virus (MVV), a lentivirus of sheep, by studying in vitro replication of vif-deleted MVV in several cell types, and the effects of vif deletion on in vivo infection. By measuring RT activity, we found that in comparison to wild-type MVV, growth of vif-deleted MVV was ...

journal_title：Virology

authors： Kristbjörnsdóttir HB,Andrésdóttir V,Svansson V,Torsteinsdóttir S,Matthíasdóttir S,Andrésson OS

更新日期：2004-01-05 00:00:00

abstract：:Hepatitis B viruses replicate via reverse transcription of an RNA intermediate. This RNA pregenome serves as mRNA and is packaged into capsids and reverse transcribed. Both processes require the interaction of the viral reverse transcriptase, P protein, with the 5'-proximal epsilon-signals on the pregenome. For epsilo...

journal_title：Virology

authors： Beck J,Bartos H,Nassal M

更新日期：1997-01-20 00:00:00

abstract：:Avian influenza A viruses of the H5 and H7 subtypes periodically cause severe outbreaks of disease in poultry. The question we wished to address in this study is whether these highly pathogenic strains constitute unique lineages or whether they and related nonpathogenic viruses are derived from common ancestors in the...

journal_title：Virology

authors： Röhm C,Horimoto T,Kawaoka Y,Süss J,Webster RG

更新日期：1995-06-01 00:00:00

abstract：:Human infections with highly pathogenic H5N1 avian influenza viruses continue to occur in many parts of the world and pose a considerable public health threat. With the use of animal models, the identification of virulence determinants has been instrumental in improving our understanding of how these viruses cause sev...

journal_title：Virology

authors： Maines TR,Chen LM,Belser JA,Van Hoeven N,Smith E,Donis RO,Tumpey TM,Katz JM

更新日期：2011-05-10 00:00:00

abstract：:West Nile virus (WNV) is a flavivirus that swept rapidly across North America in 1999, declined in prevalence, and then resurged in 2012. To date, no vaccine is available to prevent infection in the human population. Herpes simplex virus (HSV) replication-defective vaccine vectors induce a durable immunity characteriz...

journal_title：Virology

authors： Taylor TJ,Diaz F,Colgrove RC,Bernard KA,DeLuca NA,Whelan SPJ,Knipe DM

更新日期：2016-09-01 00:00:00

abstract：:An antiserum was raised against a synthetic peptide corresponding to the 18 C-terminal amino acids of a putative 16K protein encoded by the 3'-terminal open reading frame of tobacco rattle virus (TRV) RNA-1. This antiserum was used to demonstrate expression of the 16K cistron in vivo. TRV-infected tobacco protoplasts ...

journal_title：Virology

authors： Angenent GC,Verbeek HB,Bol JF

更新日期：1989-04-01 00:00:00

abstract：:Two forms of JC virus (JCV) have been isolated from its human host, an archetype found in kidney tissue and urine of nonimmunocompromised individuals and a rearranged type detected in lymphocytes and brain tissue of patients with and without progressive multifocal leukoencephalopathy. To investigate the hypothesis tha...

journal_title：Virology

authors： Daniel AM,Swenson JJ,Mayreddy RP,Khalili K,Frisque RJ

更新日期：1996-02-01 00:00:00

abstract：:Retroviral nucleocapsid (NC) proteins are small Gag-derived products containing one or two zinc finger motifs that mediate genomic RNA packaging into virions. In this study, we addressed the role of the feline immunodeficiency virus (FIV) NC protein in the late stages of virus replication by analyzing the assembly phe...

journal_title：Virology

authors： Manrique ML,Rauddi ML,González SA,Affranchino JL

更新日期：2004-09-15 00:00:00

abstract：:Essential host cofactors in retrovirus replication bind cis-acting sequences in the 5'untranslated region (UTR). Although host RBPs are crucial to all aspects of virus biology, elucidating their roles in replication remains a challenge to the field. Here RNA affinity-coupled-proteomics generated a comprehensive, unbia...

journal_title：Virology

authors： Stake M,Singh D,Singh G,Marcela Hernandez J,Kaddis Maldonado R,Parent LJ,Boris-Lawrie K

更新日期：2015-12-01 00:00:00

abstract：:Sulfolobus turreted icosahedral virus (STIV) infects Sulfolobus species found in the hot springs of Yellowstone National Park. Its 37 open reading frames (ORFs) generally lack sequence similarity to other genes. One exception, however, is ORF B116. While its function is unknown, orthologs are found in three additional...

journal_title：Virology

authors： Larson ET,Eilers BJ,Reiter D,Ortmann AC,Young MJ,Lawrence CM

更新日期：2007-07-05 00:00:00

abstract：:The 2009 influenza pandemic originated from a swine-origin H1N1 virus, which, although less pathogenic than anticipated, may acquire additional virulence-associated mutations in the future. To estimate the potential risk, we sequentially passaged the isolate A/Hamburg/04/2009 in A549 human lung epithelial cells. After...

journal_title：Virology

authors： Wörmann X,Lesch M,Welke RW,Okonechnikov K,Abdurishid M,Sieben C,Geissner A,Brinkmann V,Kastner M,Karner A,Zhu R,Hinterdorfer P,Anish C,Seeberger PH,Herrmann A,Meyer TF,Karlas A

更新日期：2016-05-01 00:00:00

abstract：:After intranasal inoculation, mouse hepatitis virus (MHV) gains entry into the central nervous system (CNS) via the olfactory and trigeminal nerves. Under the appropriate conditions, some mice develop clinically apparent demyelinating encephalomyelitis several weeks later, with virus always present in the spinal cord....

journal_title：Virology

authors： Perlman S,Jacobsen G,Olson AL,Afifi A

更新日期：1990-04-01 00:00:00

abstract：:Abnormal reinitiation of replication from lambda origins has previously been found during infection in the presence of caffeine or cis-diamminedichloroplatinum II (cis-Pt) or when lambda infects a P2 lysogen. It was further shown that the reinitiations arising from cis-Pt treatment took place during the SOS response i...

journal_title：Virology

authors： Schnös M,Inman RB

更新日期：1987-06-01 00:00:00

abstract：:Sera from 215 non-drug-injecting Toba and Mataco-Mataguayo pure Indians belonging to four communities in northern Argentina were examined using assays that allow differentiation between reactivities due to type-specific antigens of the human T-cell leukemia/lymphoma virus (HTLV). Three of these populations have very l...

journal_title：Virology

authors： Ferrer JF,Del Pino N,Esteban E,Sherman MP,Dube S,Dube DK,Basombrio MA,Pimentel E,Segovia A,Quirulas S

更新日期：1993-12-01 00:00:00

abstract：:We have utilized glycan microarray technology to determine the receptor binding properties of early isolates from the recent 2009 H1N1 human pandemic (pdmH1N1), and compared them to North American swine influenza isolates from the same year, as well as past seasonal H1N1 human isolates. We showed that the pdmH1N1 stra...

journal_title：Virology

authors： Bradley KC,Jones CA,Tompkins SM,Tripp RA,Russell RJ,Gramer MR,Heimburg-Molinaro J,Smith DF,Cummings RD,Steinhauer DA

更新日期：2011-05-10 00:00:00

abstract：:A viroid has been purified from avocado leaves infected by sunblotch disease and designated the avocado sunblotch viroid. It is a covalently closed circular RNA molecule with a molecular weight lower than that of chrysanthemum stunt viroid and citrus exocortis viroid while hybridization analysis with 32P-labeled compl...

journal_title：Virology

authors： Palukaitis P,Hatta T,Alexander DM,Symons RH

更新日期：1979-11-01 00:00:00

abstract：:Persistent infection with the Edmonston strain of measles virus (MV) has been established in IC-21 cells, an immortalized murine macrophage cell line. Persistence was established immediately without syncytia formation or cytopathic effects. MV was expressed in the majority of the cells as evidenced by immunofluorescen...

journal_title：Virology

authors： Goldman MB,Buckthal DJ,Picciotto S,O'Bryan TA,Goldman JN

更新日期：1995-02-20 00:00:00

abstract：:The phosphorylation and transcriptional competence of the free cytoplasmic form and the virion form of NS protein of vesicular stomatitis virus (VSV-Indiana/Mudd-Summers) were compared. NS protein is known to exist in two distinct phosphorylated states, NS1 and NS2, that are resolvable by gel electrophoresis. In vitro...

journal_title：Virology

authors： Masters PS,Banerjee AK

更新日期：1986-10-30 00:00:00

abstract：:Toscana (TOS) virus stocks strongly interfering with standard virus replication were obtained by sequential passages of virus in suckling mouse brain. Characterization of viral RNAs in these stocks showed the presence of a heterogeneous population of defective RNA molecules derived from the L genomic segment, in both ...

journal_title：Virology

authors： Marchi A,Nicoletti L,Accardi L,Di Bonito P,Giorgi C

更新日期：1998-06-20 00:00:00

abstract：:Many viruses utilize molecular chaperone heat shock protein 90 (Hsp90) for protein folding and stabilization, however, the role of Hsp90 in herpesvirus lifecycle is obscure. Here, we provide evidence that Hsp90 participates in pseudorabies virus (PRV) replication. Viral growth kinetics assays show that Hsp90 inhibitor...

journal_title：Virology

authors： Zhang WJ,Wang RQ,Li LT,Fu W,Chen HC,Liu ZF

更新日期：2021-01-15 00:00:00

abstract：:Porcine epidemic diarrhea virus (PEDV) is a causative agent of porcine epidemic diarrhea (PED). PED, characterized by acute diarrhea, vomiting, dehydration, has caused serious economic losses in pig industry worldwide. Here, we demonstrate that activation of a disintergrin and metalloprotease 17 (ADAM17) induced the d...

journal_title：Virology

authors： Zhang J,Guo L,Yang L,Xu J,Zhang L,Feng L,Chen H,Wang Y

更新日期：2018-04-01 00:00:00

abstract：:The results of a previous study suggested that the poly(A) sequence in barley stripe mosaic virus (BSMV) RNA is intercalated between a 3'-terminal tyrosine-accepting structure and the 5'-terminal coding part of the BSMV genome. Here we show that poly(A)+ and poly(A)- fractions of BSMV RNA can be cleaved into two fragm...

journal_title：Virology

authors： Agranovsky AA,Dolja VV,Atabekov JG

更新日期：1982-05-01 00:00:00

abstract：:Murine gammaherpesvirus 68 (MHV68) is used as a model to study gammaherpesvirus pathogenesis both in tissue culture systems and in vivo. We used a gene-trapping approach to get insight into cellular factors involved in MHV68 infection. By generating a library of gene-trapped CHO cells, we were able to isolate several ...

journal_title：Virology

authors： Jarousse N,Coscoy L

更新日期：2008-04-10 00:00:00

abstract：:Induction with ultraviolet light of K12 lysogens carrying defective prophages leads to death of the host cell. In order to determine whether the killing accompanying induction was due to diffusible phage products, or was a result of prophage excision itself, the survival of lysogens carrying DNA defective prophages on...

journal_title：Virology

authors： Eisen HA,Siminovitch L,Mohide PT

更新日期：1968-01-01 00:00:00

abstract：:Human infection with H7N9 virus has provoked global public health concern due to the substantial morbidity and mortality. Neuraminidase inhibitors (NAIs) are used as first-line drugs to treat the infection. However, virus quasispecies can evolve rapidly under drug pressure, which may alter various biological character...

journal_title：Virology

authors： Ge Y,Chi Y,Min X,Zhao K,Wu B,Wu T,Zhu X,Shi Z,Zhu F,Cui L

更新日期：2019-10-01 00:00:00