Abstract:
:Sera from 215 non-drug-injecting Toba and Mataco-Mataguayo pure Indians belonging to four communities in northern Argentina were examined using assays that allow differentiation between reactivities due to type-specific antigens of the human T-cell leukemia/lymphoma virus (HTLV). Three of these populations have very little contact with non-Indian groups and reside in remote, isolated areas. HTLV-II type-specific seroreactivity was present in 24 (13.7%) of the 175 Indians older than 13 years of age and in none of the 40 who were of younger ages. None of the Indians had antibodies reacting with HTLV-I type-specific antigen. Seroreactivity was more prevalent and appeared at younger ages in females than in males. The majority of the HTLV-II-seropositive Indians belonged to the more isolated communities. The seroprevalences among the Tobas and Mataco-Mataguayo Indians were comparable. With the exception of a Toba who was positive in a test for Treponema pallidum, no serological evidence of sexually transmitted infections with this spirochete, hepatitis B virus, hepatitis C virus, and human immunodeficiency virus was found among the Indians tested. None of the 55 non-Indian people tested in the region showed HTLV-II type-specific seroreactivity. PCR analysis of DNA isolated from peripheral blood lymphocytes of seropositive Indians confirmed that the virus present in these populations is HTLV-II. Sequence analysis of PCR-amplified genomic segments showed that the virus belongs to the HTLV-II subtype which has been found to be endemic in other Paleo-American Indians.
journal_name
Virologyjournal_title
Virologyauthors
Ferrer JF,Del Pino N,Esteban E,Sherman MP,Dube S,Dube DK,Basombrio MA,Pimentel E,Segovia A,Quirulas Sdoi
10.1006/viro.1993.1631subject
Has Abstract,Author List Incompletepub_date
1993-12-01 00:00:00pages
576-84issue
2eissn
0042-6822issn
1096-0341pii
S0042682283716314journal_volume
197pub_type
杂志文章相关文献
VIROLOGY文献大全abstract::An improved purification procedure for human astrovirus serotype 2 (H-Ast2) has facilitated the isolation of a neutralizing monoclonal antibody (PL-2) directed against one of the major structural proteins (VP26) of H-Ast2. A minor component (VP29) of the virus particles is also recognized by PL-2 antibody. Immunofluor...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1994.1296
更新日期:1994-06-01 00:00:00
abstract::Interferon gamma (IFNγ) has complex immunomodulatory and antiviral properties. While IFNγ is detected in the airways in response to infection with the pneumovirus pathogen, pneumonia virus of mice (PVM; Family Paramyxoviridae), its role in promoting disease has not been fully explored. Here, we evaluate PVM infection ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2014.07.039
更新日期:2014-11-01 00:00:00
abstract::Autoradiography of dodecyl sulfate-impregnated polyacrylamide gels after electrophoresis of the proteins from 32P-labeled cauliflower mosaic virus (CaMV) showed that two of the structural proteins were phosphorylated. These two proteins of 44 and 58 kilodaltons (kd) occur as minor components with some strains of the v...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(80)90294-9
更新日期:1980-11-01 00:00:00
abstract::In an attempt to develop an in vitro human cytomegalovirus (HCMV) latency model system, the growth characteristics of HCMV in a human thyroid papillary carcinoma cell line (TPC-1) were examined. When TPC-1 cultures preheated at 40.5 degrees for 48 hr were infected with HCMV and incubated at a supraoptimal temperature ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(87)90171-1
更新日期:1987-11-01 00:00:00
abstract::Although lentiviruses like HIV-1 are able to infect non-dividing cells, particular resting cells such as non-stimulated primary peripheral blood mononuclear cells (PBMC) are resistant to infection. In contrast to other lentiviruses, SIVsmmPBj can replicate in non-stimulated PBMC. Moreover, SIVsmmPBj-derived, but not H...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2007.03.008
更新日期:2007-08-01 00:00:00
abstract::Thymidine kinase-deficient syrian hamster cells were cotransfected with recombinant plasmids containing the thymidine kinase (TK) gene of Herpes Simplex Virus Type 1, and either intact or partially deleted SV40 T antigen-coding genes. The transformants were selected by their ability to grow in gHAT medium. After selec...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(84)90287-3
更新日期:1984-04-15 00:00:00
abstract::The LP-BM5 retrovirus, a complex containing ecotropic helper, recombinant MCF, and defective retroviruses, causes an immunodeficiency-termed mouse AIDS (MAIDS). Many disease features of MAIDS resemble those of AIDS, including terminal B cell lymphomas. Previously we generated from MAIDS-susceptible C57BL/6 mice cytoly...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1994.1189
更新日期:1994-04-01 00:00:00
abstract::Norwalk virus (NV) is the prototype strain of a group of noncultivatable caliciviruses that infect humans and cause outbreaks of epidemic acute nonbacterial gastroenteritis. The NV virion is composed of 180 copies of a single structural protein that, when expressed in insect cells infected with a recombinant baculovir...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1996.0112
更新日期:1996-03-01 00:00:00
abstract::The recent development of in vitro hepatitis C virus (HCV) RNA replication systems has provided useful tools for studying the intracellular anti-HCV activity of ribavirin. Ribavirin has been shown to: (1) induce "error catastrophe" in poliovirus, Proc. Natl. Acad. Sci. USA 98, 6895-6900), (2) be a pseudo-substrate of ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/s0042-6822(03)00152-1
更新日期:2003-06-05 00:00:00
abstract::The genomic RNAs of barley stripe mosaic virus (BSMV) were used in experiments involving site-specific cleavage to yield noninfective but functionally active fragments and subsequent restoration of infectious viral RNA by means of religation. The specific fragments were obtained after site-specific cleavage of BSMV RN...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(87)90469-7
更新日期:1987-08-01 00:00:00
abstract::To study the process of membrane fusion in Morbilliviruses, the fusion (F) glycoproteins of Peste des petits ruminants virus (PPRV) and Rinderpest virus (RPV) were expressed transiently in mammalian cells. The recombinant F proteins were found to be localized at the surface of transfected cells. The fusion activity, a...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.2001.1120
更新日期:2001-10-10 00:00:00
abstract::A previous study suggested that the genomes of the arenaviruses native to North America are a product of genetic recombination between New World arenaviruses with significantly different phylogenetic histories. The purpose of this study was to extend our knowledge of the principal host relationships and evolutionary h...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2007.05.031
更新日期:2007-10-25 00:00:00
abstract::Because phosphorylation of the infectious bronchitis virus (IBV) nucleocapsid protein (N) may regulate its multiple roles in viral replication, the dynamics of N phosphorylation were examined. 32P-orthophosphate labeling and Western blot analyses confirmed that N was the only viral protein that was phosphorylated. Pul...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2005.04.029
更新日期:2005-08-15 00:00:00
abstract::We previously analyzed hybrids of Cucumber mosaic virus (CMV) and Tomato aspermy virus (TAV) that contained CMV RNA2 with the 3'-terminal sequence from TAV RNA2. In this article, we scrutinized the RNA3 molecules in these hybrid viruses by Northern hybridization and RT-PCR and found some recombinant CMV RNA3 molecules...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/s0042-6822(02)00050-8
更新日期:2003-02-01 00:00:00
abstract::The Epstein-Barr virus nuclear antigen 2A (EBNA-2A) has been strongly implicated in the EBV-mediated B-cell transformation process. Since EBNA-2A might exert this function through interaction with proteins of the infected cell, we studied the association of EBNA-2A with cellular proteins. Immunoprecipitation of EBNA-2...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1993.1406
更新日期:1993-08-01 00:00:00
abstract::Insertion of a functional splicing cassette into a construct containing the HIV-1 poly(A) site followed by the adenovirus L3 poly(A) site results in both specific stimulation of 3' end processing at the HIV-1 site and an increase in the steady-state levels of RNA processed at both sites. To further evaluate this influ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1996.0556
更新日期:1996-10-15 00:00:00
abstract::Red sea bream iridovirus (RSIV) of the Iridoviridae family is a causative agent of lethal infections in many cultured marine fish species in southwestern Japan. RSIV-induced apoptosis was divided as follows: (1). cell shrinkage and rounding at the early apoptotic stage, (2). cell enlargement at the middle apoptotic st...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2004.02.006
更新日期:2004-05-01 00:00:00
abstract::Previous studies have shown that a 558-bp fragment of human cytomegalovirus (CMV) DNA contained within pCM4127 and designated CMV mtr can morphologically transform rodents cells in vitro. By cotransformation with pCM4127 and a plasmid conferring G418 resistance, pSV2neo, morphologically transformed NIH3T3 cell lines w...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(87)90437-5
更新日期:1987-01-01 00:00:00
abstract::The genome of the single-stranded DNA phage f1 contains an intergenic region (IG), 508-nucleotides long, that does not code for any known protein. By use of a system of chimeric plasmids haboring different f1 fragments, we had previously shown that this region contains, in addition to the f1 'functional origin' of DNA...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(83)90136-8
更新日期:1983-10-15 00:00:00
abstract::To examine whether there are HBV variants not yet described which cannot express HBe due to a mutation in the pre-C region, and, if they exist, whether they cause a particular course of infection and disease, we analyzed the HBV genomes of a HBs/anti-HBe positive chronic carrier who had several episodes of acute reexa...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(90)90274-u
更新日期:1990-11-01 00:00:00
abstract::Coronaviruses have a marked tropism for epithelial cells. Entry and release of the porcine transmissible gastroenteritis virus (TGEV) is restricted to apical surfaces of polarized epithelial cells, as we have recently shown (J. W. A. Rossen, C. P. J. Bekker, W. F. Voorhout, G. J. A. M. Strous, A. van der Ende, and P. ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1995.1316
更新日期:1995-06-20 00:00:00
abstract::CD8 T cells play an important role in controlling Ebola infection and in mediating vaccine-induced protective immunity, yet little is known about antigenic targets in Ebola that are recognized by CD8 T cells. Overlapping peptides were used to identify major histocompatibility complex class I-restricted epitopes in mic...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2003.09.016
更新日期:2004-01-05 00:00:00
abstract::A nonhemagglutinating mutant of a 1978 isolate of canine parvovirus (CPV) was derived after repeated passages in the NLFK feline kidney cell line. The mutant CPV was antigenically indistinguishable from wild-type virus when tested with 82 monoclonal antibodies, and it replicated in cat and dog cell lines in culture. S...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(88)90255-3
更新日期:1988-03-01 00:00:00
abstract::The interferon sensitivity of the expression of an influenza-virus hemagglutinin (HA) gene cloned into the thymidine kinase (TK) gene of vaccinia virus was studied in chick embryo fibroblasts (CEF) and Madin-Darby bovine kidney (MDBK) cells. In CEF, the expression of the HA gene is inhibited by pretreatment of cells w...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(92)90740-g
更新日期:1992-05-01 00:00:00
abstract::Hantaviruses are enveloped RNA viruses that belong to the family Bunyaviridae. They are the causative agents of hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). Hantaviruses show a worldwide distribution with specific rodent species as natural hosts. It is known that rodents can tr...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2003.09.006
更新日期:2004-01-05 00:00:00
abstract::We have investigated the role of vif in maedi-visna virus (MVV), a lentivirus of sheep, by studying in vitro replication of vif-deleted MVV in several cell types, and the effects of vif deletion on in vivo infection. By measuring RT activity, we found that in comparison to wild-type MVV, growth of vif-deleted MVV was ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2003.09.044
更新日期:2004-01-05 00:00:00
abstract::The budded phenotype of Autograha californica nuclear polyhedrosis virus (AcNPV BV) has a 64K glycoprotein in its envelope which is important in the ability of the virus to functionally enter host cells. Tunicamycin (TM), an inhibitor of N-linked glycosylation, was used to determine whether the sugar moiety was essent...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(86)90443-5
更新日期:1986-10-15 00:00:00
abstract::Lipid binding properties which are dependent on exposure to acid pH are an important mechanism for the cellular entry pathway for some enveloped viruses and for other macromolecules. Cell-to-cell fusion can be used to demonstrate this function. La Crosse virus, a member of the family Bunyaviridae, fused BHK-21 cells f...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(84)90107-7
更新日期:1984-01-15 00:00:00
abstract::The transcription/replication activity of ribonucleoproteins derived from influenza A primary isolates of human (A/Paris/908/97) or avian origin (A/Mallard/Marquenterre/MZ237/83, A/Hong Kong/156/97) was compared upon reconstitution in mammalian or avian cells, using viral-like reporter RNAs synthesized under the contr...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2006.12.027
更新日期:2007-06-05 00:00:00
abstract::Human adenovirus (HAdV) is a cause of significant morbidity and mortality in immunocompromised patients, especially after stem cell transplantation (SCT). Viral clearance has been attributed to CD4(+) T-cell responses against the Hexon-protein, but the frequency of specific T(HELPER) cells is extremely low or not dete...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2009.10.049
更新日期:2010-02-20 00:00:00