Productive infection of CD34+-cell-derived megakaryocytes by X4 and R5 HIV-1 isolates.

abstract：:Serial passage of Ross River virus in chick embryo fibroblasts selected for virus variants altered in their reactions to neutralizing monoclonal antibodies. The E1 and E2 genes of each antigenic variant were sequenced; single nucleotide changes were found in E2 leading to amino acid substitutions at either residue 4 (...

journal_title：Virology

authors： Kerr PJ,Weir RC,Dalgarno L

更新日期：1993-03-01 00:00:00

abstract：:The alphaherpesviruses establish latent infections in sensory neuronal cells, during which a number of latency-associated RNA transcripts (LATs) are produced. The reasons for the production of the LATs, however, and the mechanism by which the LAT region of the genome remains active during latency are unknown. Here we ...

journal_title：Virology

authors： Coffin RS,Howard MK,Latchman DS

更新日期：1995-06-01 00:00:00

abstract：:Coat protein-protected fragments of alfalfa mosaic virus RNA (AlMV-RNA) and tobacco streak virus RNA (TSV-RNA), which were isolated as described [D. Zuidema, M. F. A. Bierhuizen, B. J. C. Cornelissen, J. F. Bol, and E. M. J. Jaspars (1983)Virology, 125, 361-369], were tested for their ability to rebind AlMV coat prote...

journal_title：Virology

authors： Zuidema D,Cool RH,Jaspars EM

更新日期：1984-07-30 00:00:00

abstract：:The influenza A virus nucleoprotein previously expressed in Escherichia coli after fusion to 32 heterologous amino acids has now been purified and tested for its ability to form complexes with RNA in vitro. By using a simple filter binding assay, we show that ribonucleoprotein (RNP) complexes form readily with single-...

journal_title：Virology

authors： Kingsbury DW,Jones IM,Murti KG

更新日期：1987-02-01 00:00:00

abstract：:In situ hybridization of viral DNA fragments to metaphase chromosomes of two chicken T-lymphoblastoid cell lines (MDCC) demonstrated that Marek's disease virus DNA was located in the short arm of chromosome 2 of MDCC-MSB1 and MDCC-RP1 cells and in the short arm of chromosome 4 of MDCC-MSB1 cells. The MDV DNA sequences...

journal_title：Virology

authors： Hirai K,Maotani K,Ikuta K,Yasue H,Ishibashi M,Kato S

更新日期：1986-07-15 00:00:00

abstract：:Recently, the product of equine herpesvirus type 1 (EHV-1) ORF1, a homolog to HSV-1 pUL56, was shown to modulate MHC-I expression and innate immunity. Here, we investigated modulation of respiratory epithelial immunity by EHV-1 pUL56 and compared responses to those of PBMCs, which are important target cells that allow...

journal_title：Virology

authors： Soboll Hussey G,Ashton LV,Quintana AM,Van de Walle GR,Osterrieder N,Lunn DP

更新日期：2014-09-01 00:00:00

abstract：:VP5, a 5'-terminal, small open reading frame in segment A of the aquatic birnavirus (infectious pancreatic necrosis virus, IPNV) genome, encodes a 17-kDa nonstructural protein. We previously reported apoptosis induced by IPNV in a fish cell line. In the present study, we cloned and identified VP5 and tested its functi...

journal_title：Virology

authors： Hong JR,Gong HY,Wu JL

更新日期：2002-04-10 00:00:00

abstract：:Two bipartite begomoviruses, Indian cassava mosaic virus (ICMV) and Sri Lankan cassava mosaic virus (SLCMV), have been isolated from mosaic-diseased cassava originating from central India and Sri Lanka, respectively. ICMV was transmitted with low efficiency from cassava to Nicotiana benthamiana by sap inoculation to g...

journal_title：Virology

authors： Saunders K,Salim N,Mali VR,Malathi VG,Briddon R,Markham PG,Stanley J

更新日期：2002-02-01 00:00:00

abstract：:An essentially complete DNA copy of the ambisense S RNA species of Punta Toro (PT) phlebovirus (T. Ihara, H. Akashi, and D.H.L. Bishop, 1984, Virology 136, 293-306) has been inserted in either orientation into Autographa californica nuclear polyhedrosis baculovirus (AcNPV) in lieu of the 5' coding region of the AcNPV ...

journal_title：Virology

authors： Overton HA,Ihara T,Bishop DH

更新日期：1987-04-01 00:00:00

abstract：:Murine gammaherpesvirus 68 (MHV68) is used as a model to study gammaherpesvirus pathogenesis both in tissue culture systems and in vivo. We used a gene-trapping approach to get insight into cellular factors involved in MHV68 infection. By generating a library of gene-trapped CHO cells, we were able to isolate several ...

journal_title：Virology

authors： Jarousse N,Coscoy L

更新日期：2008-04-10 00:00:00

abstract：:The members of the c-myb proto-oncogene family encode sequence-specific transcriptional activators. In T cells, expression of c-myb and the related B-myb gene is induced following mitogenic stimulation. Using a purified recombinant protein, we report here that the human T cell lymphotropic virus type 1 (HTLV-1) LTR c...

journal_title：Virology

authors： Bosselut R,Lim F,Romond PC,Frampton J,Brady J,Ghysdael J

更新日期：1992-02-01 00:00:00

abstract：:The virulence factor of Melon necrotic spot virus (MNSV), a virus that induces systemic necrotic spot disease on melon plants, was investigated. When the replication protein p29 was expressed in N. benthamiana using a Cucumber mosaic virus vector, necrotic spots appeared on the leaf tissue. Transmission electron micro...

journal_title：Virology

authors： Mochizuki T,Hirai K,Kanda A,Ohnishi J,Ohki T,Tsuda S

更新日期：2009-08-01 00:00:00

abstract：:The noncapsid protein expressed from ORF-206 of turnip yellow mosaic virus (TYMV) is autocatalytically processed by a papain-like protease, producing N-terminal 150-kDa and C-terminal 70-kDa proteins. By introducing two methionine residues near the N-terminus of the 70-kDa protein, we have obtained N-terminal amino ac...

journal_title：Virology

authors： Bransom KL,Wallace SE,Dreher TW

更新日期：1996-03-01 00:00:00

abstract：:We previously demonstrated that Bombyx mori nucleopolyhedrovirus (BmNPV) multiplication is restricted in permissive BmN-4 cells upon coinfection with Hyphantria cunea NPV (HycuNPV). Here, we show that HycuNPV-encoded hycu-ep32 gene is responsible for the restricted BmNPV multiplication in HycuNPV-coinfected BmN-4 cell...

journal_title：Virology

authors： Shirata N,Ikeda M,Kobayashi M

更新日期：2010-03-15 00:00:00

abstract：:Multiple RNA species which hybridize to a cloned cDNA probe of the turnip crinkle virus satellite RNA (S-TCV) are found both in virions and in plants infected with virus particles containing S-TCV. At least six of these RNAs appear to be multimeric forms of the satellite RNA based on their migration in denaturing gels...

journal_title：Virology

authors： Altenbach SB,Howell SH

更新日期：1984-04-15 00:00:00

abstract：:A nonhemagglutinating mutant of a 1978 isolate of canine parvovirus (CPV) was derived after repeated passages in the NLFK feline kidney cell line. The mutant CPV was antigenically indistinguishable from wild-type virus when tested with 82 monoclonal antibodies, and it replicated in cat and dog cell lines in culture. S...

journal_title：Virology

authors： Parrish CR,Burtonboy G,Carmichael LE

更新日期：1988-03-01 00:00:00

abstract：:We report the isolation and characterization of HEp-2c cell clones obtained after two successive persistent poliovirus (PV) infections. Once cured, some of the cell clones displayed selective permissivity toward the wild-type Mahoney strain and partial resistance to particular mutants of this strain, including the Sab...

journal_title：Virology

authors： Calvez V,Pelletier I,Couderc T,Pavio-Guédo N,Blondel B,Colbère-Garapin F

更新日期：1995-10-01 00:00:00

abstract：:In transient gene expression assays we observed an increase in expression of the bacterial chloramphenicol acetyl-transferase (CAT) gene, under the transcriptional control of the HIV-1 LTR (pLTR-CAT), when this plasmid was cotransfected into Vero or MRC-5 cells with a plasmid containing either the HCMV immediate early...

journal_title：Virology

authors： Rando RF,Srinivasan A,Feingold J,Gonczol E,Plotkin S

更新日期：1990-05-01 00:00:00

abstract：:We present a case of sexual transmission of HIV-1 predicted to have CXCR4-tropism during male-to-male sexual exposure. Phylogenetic analyses exclude cell-free virus in the seminal plasma of the source partner and possibly point to the seminal cells as the origin of the transmission event. ...

journal_title：Virology

authors： Gianella S,Mehta SR,Young JA,Vargas MV,Little SJ,Richman DD,Kosakovsky Pond SL,Smith DM

更新日期：2012-12-05 00:00:00

abstract：:We have shown that the binding of simian immunodeficiency virus (SIV) to Jurkat T cells expressing CD4 receptor strongly induces mitogen-activated protein (MAP) kinase kinase (MEK) and extracellular signal-regulated kinases 1 and 2 (ERK1/2) and only weakly induces p38 MAP kinase and c-Jun N-terminal kinase (JNK). Simi...

journal_title：Virology

authors： Popik W,Pitha PM

更新日期：1998-12-05 00:00:00

abstract：:Little is known about antigen-specific T-cell responses to viruses in teleosts due to a lack of a suitable experimental system using inbred or clonal animals. In the present study we have successfully induced an in vitro generation of virus-specific cytotoxic T-cells (CTLs) from isogeneic ginbuna crucian carp. Respond...

journal_title：Virology

authors： Somamoto T,Okamoto N,Nakanishi T,Ototake M,Nakao M

更新日期：2009-06-20 00:00:00

abstract：:Herpes simplex virus 1 (HSV-1) infection induces changes to the host cell nucleus including relocalization of the cellular protein Upstream Binding Factor (UBF) from the nucleolus to viral replication compartments (VRCs). Herein, we tested the hypothesis that UBF is recruited to VRCs to promote viral DNA replication. ...

journal_title：Virology

authors： Ouellet Lavallée G,Pearson A

更新日期：2015-09-01 00:00:00

abstract：:A mutant (Tbts7) of alfalfa mosaic virus, the coat protein of which is unable to activate the viral genome (the RNA species 1, 2, and 3, which need some coat protein for infectivity) at 30 degrees , can be rescued at this temperature by adding to the inoculum wild-type RNA 3 (the genome part that contains the coat pro...

journal_title：Virology

authors： Smit CH,Jaspars EM

更新日期：1982-02-01 00:00:00

abstract：:Little is known about the neutralization properties of HIV-1 in India to optimally design and test vaccines. For this reason, a functional Env clone was obtained from each of ten newly acquired, heterosexually transmitted HIV-1 infections in Pune, Maharashtra. These clones formed a phylogenetically distinct genetic li...

journal_title：Virology

authors： Kulkarni SS,Lapedes A,Tang H,Gnanakaran S,Daniels MG,Zhang M,Bhattacharya T,Li M,Polonis VR,McCutchan FE,Morris L,Ellenberger D,Butera ST,Bollinger RC,Korber BT,Paranjape RS,Montefiori DC

更新日期：2009-03-15 00:00:00

abstract：:We have recently described the cloning of a portion of the hepatitis E virus (HEV) and confirmed its etiologic association with enterically transmitted (waterborne, epidemic) non-A, non-B hepatitis. The virus consists of a single-stranded, positive-sense RNA genome of approximately 7.5 kb, with a polyadenylated 3' end...

journal_title：Virology

authors： Tam AW,Smith MM,Guerra ME,Huang CC,Bradley DW,Fry KE,Reyes GR

更新日期：1991-11-01 00:00:00

abstract：:The genome of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) contains four structural genes that are homologous to genes found in other coronaviruses, and also contains six subgroup-specific open reading frames (ORFs). Expression of one of these subgroup-specific genes, ORF7a, resulted in apoptosi...

journal_title：Virology

authors： Yuan X,Wu J,Shan Y,Yao Z,Dong B,Chen B,Zhao Z,Wang S,Chen J,Cong Y

更新日期：2006-03-01 00:00:00

abstract：:Human embryo lung cells pretreated with a combination of human leukocyte interferon and acyclovir were infected with human cytomegalovirus (HCMV) and treated daily for 14 days with the same inhibitor combination. After removal of the inhibitors, the incubation temperature was maintained at either 37 or 40.5 degrees. I...

journal_title：Virology

authors： Bucher LJ,Wigdahl B,Rapp F

更新日期：1983-10-15 00:00:00

abstract：:The recent identification of a novel human coronavirus responsible of a SARS-like illness in the Middle-East a decade after the SARS pandemic, demonstrates that reemergence of a SARS-like coronavirus from an animal reservoir remains a credible threat. Because SARS is contracted by aerosolized contamination of the resp...

journal_title：Virology

authors： Escriou N,Callendret B,Lorin V,Combredet C,Marianneau P,Février M,Tangy F

更新日期：2014-03-01 00:00:00

abstract：:The HSV-1 genome is composed of two unique regions (UL and US) flanked by inverted repeats. During the course of DNA replication the two unique regions UL and US invert relative to one another. In this report we present evidence that cleavage is not necessary for genomic inversion to occur. We isolated and characteriz...

journal_title：Virology

authors： Lamberti C,Weller SK

更新日期：1996-12-15 00:00:00

abstract：:Human immunodeficiency virus (HIV) encodes a transacting protein, Rev, which interacts with an RNA element (RRE) to mediate nuclear export of unspliced viral mRNA. Recently, the RNA constitutive transport elements (CTE) from Mason-Pfizer monkey virus (MPMV) and simian retrovirus type I (SRV-1) were shown to render Rev...

journal_title：Virology

authors： Tang H,Xu Y,Wong-Staal F

更新日期：1997-02-17 00:00:00